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4-Amino-3-Nitro-N,N-Dimethylaniline

    • Product Name 4-Amino-3-Nitro-N,N-Dimethylaniline
    • Alias 4-amino-3-nitro-N,N-dimethylaniline
    • Einecs 217-959-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    541181

    Chemical Name 4-Amino-3-Nitro-N,N-Dimethylaniline
    Molecular Formula C8H11N3O2
    Molecular Weight 181.19 g/mol
    Cas Number 99-59-2
    Appearance Yellow to orange crystalline powder
    Melting Point 148-150°C
    Solubility Slightly soluble in water
    Density 1.23 g/cm3 (approximate)
    Boiling Point Decomposes before boiling
    Pubchem Cid 7333
    Synonyms N,N-Dimethyl-4-amino-3-nitroaniline
    Storage Conditions Store at room temperature, away from light and moisture
    Smiles CN(C)C1=CC(=C(C=C1N)[N+](=O)[O-])
    Inchi InChI=1S/C8H11N3O2/c1-11(2)7-4-6(9)5-8(3-7)10(12)13/h3-5H,9H2,1-2H3
    Hazard Classification Irritant

    As an accredited 4-Amino-3-Nitro-N,N-Dimethylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 4-Amino-3-Nitro-N,N-Dimethylaniline is packed in a tightly sealed amber glass bottle with hazard labels and product details.
    Shipping 4-Amino-3-Nitro-N,N-Dimethylaniline is shipped in tightly sealed containers, protected from light, moisture, and incompatible materials. It is classified as a hazardous chemical; therefore, it is transported following relevant national and international regulations, including labeling for toxicity and environmental hazards. Special care is taken to avoid physical shock during transit.
    Storage **4-Amino-3-Nitro-N,N-Dimethylaniline** should be stored in a tightly sealed container, away from light, heat, and incompatible substances such as strong oxidizers and acids. Store in a cool, dry, and well-ventilated area, preferably in a dedicated chemical storage cabinet. Ensure proper labeling and follow all regulatory requirements for hazardous organic compounds. Avoid exposure to moisture and ignition sources.
    Application of 4-Amino-3-Nitro-N,N-Dimethylaniline

    Applications of 4-Amino-3-Nitro-N,N-Dimethylaniline in Industrial Manufacturing

    4-Amino-3-Nitro-N,N-Dimethylaniline is a specialized intermediate used chiefly in the synthesis of certain specialty dyes, color developers, and pharmaceutical intermediates. Its selective chemical properties support efficient manufacturing processes in key downstream segments, where precise formulation control and adherence to specific industry standards are critical for product quality and regulatory compliance. Below, we detail its established applications within several advanced chemical industries.

    1. Azo Dye Synthesis for Polyester Fiber Coloring

    This ingredient acts as a key diazo component in the formulation of disperse and solvent dyes used in coloring synthetic fibers, especially polyester. The material’s specific substitution profile enhances the brightness and wash-fastness of yellow and orange shades. It enters the downstream process during the coupling step, where careful control of dosage ensures batch reproducibility and endpoint consistency, complying with textile chemicals regulations and eco-label requirements for synthetic fiber coloration.

    Industry compliance standards

    • OEKO-TEX® Standard 100
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals Manufacturing Restricted Substances List)
    • REACH Regulation (EC) No 1907/2006
    • GB/T 29862-2013 (Identification of Fiber Content in Textiles)

    Typical usage ratio

    • 0.4–3.2% by weight in dye formulation; exact ratio adjusted according to target shade and dye-bath reactivity*

    Downstream process integration

    • Added at the azo-coupling reaction with pre-diazotized aromatic amines to generate target dye precursor
    • Integrated early in the batch or continuous dye synthesis cycle

    Final product types

    • Disperse dyes for polyester textiles
    • Solvent dyes used in plastics and coatings
    • Colorants for PET fiber and film

    2. Photographic Color Developer Production

    Within the color photographic industry, this intermediate supports the synthesis of specific developer agents used in the emulsion layers of color photographic film and paper. Manufacturers rely on this compound when formulating developers that require precise electron-donating and -withdrawing characteristics, ensuring stable image formation and long-term photographic quality that are subject to international photographic standards and processing protocols.

    Industry compliance standards

    • ISO 18902:2013 (Imaging Materials – Processed Films)
    • ANSI IT9.9 (Photographic Processing Chemicals)
    • RoHS (Restriction of Hazardous Substances Directive 2011/65/EU)

    Typical usage ratio

    • 0.05–0.12 molar equivalents per developer batch; determined according to required color density and developer activity

    Downstream process integration

    • Used at the coupling reagent synthesis step for preparing color developer concentrates
    • Introduced in controlled, pH-regulated environments to prevent by-product formation

    Final product types

    • Color film and RA-4 photo paper developers
    • Photographic emulsion stabilizers
    • Press-chemistry color developer kits

    3. Active Pharmaceutical Ingredient (API) Intermediate in Analgesic Synthesis

    This aromatic amine compound functions as a building block for certain non-opioid analgesic APIs, especially for downstream investigation drugs and experimental compounds used in research and limited clinical trials. Process engineers introduce it during the amination or nitration steps of multistep syntheses, emphasizing strict compliance with GMP requirements and detailed batch traceability for pharmaceutical applications where material provenance and purity are mission-critical.

    Industry compliance standards

    • ICH Q7 – Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 211
    • EU GMP Part II (APIs)

    Typical usage ratio

    • 0.7–1.5 molar equivalents per batch of target API intermediate; adjusted to desired conversion rate during synthesis steps

    Downstream process integration

    • Used as an amine nucleophile or nitroaromatic precursor during multi-step organic transformations
    • Dosed at controlled stages in GMP-certified reactors under validated cleaning and transfer protocols

    Final product types

    • Intermediate compounds for experimental non-opioid analgesics
    • Investigational small-molecule candidates

    4. Chemical Markers for Oil Industry Tracer Studies

    Refining and upstream oilfield service companies utilize this compound in formulating chemical markers for process tracing and leak detection. It provides a unique, detectable chromophore that allows robust quantification in multi-phase systems, and its integration must align with environmental and safety standards for tracer chemicals.

    Industry compliance standards

    • API Manual of Petroleum Measurement Standards (MPMS)
    • CFR Title 40 – Environmental Protection (for tracer chemicals)
    • REACH Regulation (EC) No 1907/2006 (as relevant for transport and downstream handling)

    Typical usage ratio

    • 5–80 ppm in oil or process streams; actual concentration set based on detection requirements and equipment sensitivity

    Downstream process integration

    • Blended in as a tracer during hydrocarbon transfer, crude blending, or leak diagnostic protocols
    • Introduced to process lines through automated chemical injection equipment

    Final product types

    • Tracer-tagged crude oil and refined product batches
    • Process diagnostic fluid samples

    5. Precursor for Liquid Crystal Dye Additives

    The electronics and display industry applies this compound as a synthetic building block for specialty dye molecules used as color filters and alignment layer additives in liquid crystal display (LCD) technology. These dyes must meet rigorous photostability and purity specifications, with downstream integration primarily in microelectronic component manufacturing lines governed by strict material and process guidelines.

    Industry compliance standards

    • IEC 61249-2-21:2003 (Materials for printed boards, halogen-free base)
    • RoHS Directive 2011/65/EU (Directive on the restriction of hazardous substances in electrical and electronic equipment)
    • JEITA QC 080000 (Hazardous Substance Process Management System)

    Typical usage ratio

    • 0.2–1.0% by solid content in dye precursor formulation for alignment layer or filter manufacturing; final ratio tuned according to downstream color density and UV tolerance

    Downstream process integration

    • Incorporated at the dye precursor synthesis and post-column purification steps
    • Feeds directly into inkjet or micro-patterning systems for panel manufacture

    Final product types

    • Color filter dyes for LCD and OLED display modules
    • Alignment layer performance additives
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    Certification & Compliance
    More Introduction

    Introducing 4-Amino-3-Nitro-N,N-Dimethylaniline: Applied Chemistry Rooted in Craft

    Understanding What Makes Our Product Distinct

    At the heart of our daily work on the factory floor, 4-Amino-3-Nitro-N,N-Dimethylaniline carries a reputation built not only in laboratory papers but through the results seen across customer applications. Produced through selective nitration and methylation, our batches run with consistency shaped by years of hands-on experience. We work closely with chemists and engineers who depend on steady supply and predictable composition to develop colorants, specialty dyes, and genuine research innovation. We notice performance not by abstract claims but through measurable results: clean spectra, reliable yields, and fewer headaches downstream.

    Our model, labeled by many as superior in both color development and stability, genuinely stands out in the crowd. The most defining features rest inside purity and the way our process limits byproduct formation. Small differences in raw input and water content make big differences later in the workflow. Even a subtle trace of impurities echoes through into the dye, or the advanced intermediates derived from this starting block. We contend with these factors in real time, re-checking each run and never shying away from hands-on troubleshooting.

    Specifications Shaped by Decades of Hands-On Work

    The chemical formula of 4-Amino-3-Nitro-N,N-Dimethylaniline brings together a fine balance: the amino and nitro groups sit on the aromatic ring, with a dimethylamino group micromanaging electron flow. Chemists draw this structure in ink, but as the manufacturer, we see it as something tangible—an orange crystalline solid, typically displaying a melting point in the 90–95°C range, and reliable solubility in polar organic solvents. These are not marketing claims. This is the product that emerges from stainless reactor vessels after every batch. Each lot draws rigorous HPLC and GC checks, not because regulations demand it, but because we’ve lived through the aftermath of trace contamination in finished colorants. The result speaks in consistent grain size, dustless handling, and ease of integration in complex organic synthesis.

    Specifications often act as a laundry list, but what matters in a real setting is how the product cooks. Purity usually runs upwards of 98%, generally maintaining tight control on moisture—all critical for downstream coupling reactions. Color and shade consistency avoids surprises on your end product. These concrete properties affect every application, from molecular diagnostics to inkjet dispersions. A lot of what is called ‘acceptable’ on paper brings only frustration in the workshop: clumping powders, erratic shade strength, or flaked purity. Our approach does not default to the minimum; it is calibrated through trials, user feedback, and lessons collected over years.

    How We Prepare 4-Amino-3-Nitro-N,N-Dimethylaniline for Real-World Use

    Manufacturing does not halt at synthesizing the molecule. We think about transport, storage, and user comfort. Packing matters as much as chemical purity. Several clients mentioned static buildup with other materials. We responded with antistatic inner linings and tighter seals. Some need bulk, others call for small drums—an adaptation we handle not out of favor but from continuous dialogue with end users.

    Handling qualities create major differences. This molecule enjoys good stability under ambient storage, but we learned to keep conditions dry as a rule, avoiding product bridging or caking. In our early days, a humid warehouse meant lost cargo after only one summer cycle. Careful storage prevents spoiling and keeps the shelf life to maximum possible periods, which can differ based on climate, but we aim for two years unbroken.

    Downstream compatibility is a question we hear often. We have worked with research and pilot plant teams that want to use this intermediate for coupling reactions. What they see from us is predictable reactivity time after time, batch after batch. Differences you may notice with market alternatives often trace back to trace-level stabilizers or incomplete washing stages in production. These imperfections show up as ghostly impurities in NMR and halt process scale-ups before they even properly begin.

    Where Our Product Finds Its Footing

    The central use for 4-Amino-3-Nitro-N,N-Dimethylaniline ties to colorant and dye synthesis. This molecule stands as a solid junction between high-quality azo dyes and various functional intermediates. Some R&D groups apply it to manufacture advanced photosensitive materials or unique pigments. Each application demands a certain reliability—near-total purity, precise physical form, and the ability to withstand a variety of reaction conditions without shifting shade or spewing out mystery byproducts.

    Over recent years, specialized applications have grown. Researchers experimenting with photochemical sensors count on its distinct chromophoric groups. A few start-ups in the biotech sphere explore its coupling properties for molecular tagging. For established users in fabric, paper, or ink industries, it continues its role as a base for large-scale dye production. We support labs who need single-kilogram lots for discovery work, as well as plant-scale partners drawing from tonnage. Our team often receives requests for guidance alongside orders, giving advice based on both our experience and supply chain contacts. We share what works, and just as importantly, what has failed.

    Direct Experience—Why Differences Matter

    Market options for 4-Amino-3-Nitro-N,N-Dimethylaniline look similar at first glance. Details shift the story. Some manufacturers cut corners on the source aniline, resulting in unwanted trace metals or secondary amines. These turn small differences into major obstacles for end users, especially in strict applications like electronics or medical diagnostics. We source only high-grade starting material certified for organic synthesis, even if it eats into our margins. Years on the chemical floor taught us that rebuilding reputation costs more than upfront savings.

    Shipping is another topic where the difference emerges. Bulk operations from some plants lead to irregular grain sizes, packing inconsistencies, and impossible dust hazards. Our method keeps grain size controlled—a judgment gained by direct feedback from clients who complained about needle-like crystals jamming automatic feeders. We altered drying stages, shifted sieving mesh sizes, and checked the result on our own line. Employees noticed fewer allergic reactions, loaders noted better flow, and production downtime dropped. The improvements stuck.

    Our Quality Control: Not an Afterthought, a Foundation

    Each drum, sack, or container runs through multiple internal control steps beyond any regulator’s checklist. HPLC sampling, wet-chemistry checks, and stability testing provide the data we need, but they follow from the practical. If a sample acts up in our own test bench, we do not ship it. Some companies showcase certificates; we trust process transparency more. Our QC staff work on rotating shifts to maintain fresh eyes and share informal hints: a slight change in odor, unexpected residue, or even a small visual off-color. Once, a batch drifted off tolerance because of an unnoticed variation in a raw nitro compound. Sharp-eyed staff picked it up within hours, and production stopped long enough to isolate the issue.

    Routine matters more than theoretical possibilities. We keep back-reference samples from every outgoing shipment, not from bureaucratic habit, but to allow for cross-verification if any downstream client faces difficulties. In rare cases of user-reported concerns, our technical team pulls the reference sample, cross-examines analysis data, and talks directly with the chemist or engineer. Over almost three decades, these practices have built trust not just with end-users, but with regional safety agencies and university partners.

    Upgrade Paths: Customization and Technical Collaboration

    Over time, our customers’ needs have changed. Sometimes they require adjustments not found in ordinary product lists—tighter moisture limits, reduced residual solvents, or customized blending for research platforms. We welcome such challenges, not with a templated "customization" promise, but through technical dialogue, trial batches, and live feedback. Our team understands the pain points present in manufacturing specialty dyes using this material. Some partners encountered trouble with inconsistent performance caused by variable lots. We worked alongside them to identify causes—often minute details such as variation in methylating agent or solvent contamination—and corrected procedures accordingly.

    Sometimes, a partner approaches us with new safety or regulatory expectations for export. Our team stays current with REACH and other major compliance standards—not just ticking boxes, but sharing best practices with customer compliance officers. We’ve walked through surprise audits with inspectors from multiple continents, showcasing not just documents but the living systems that govern production and shipping workflow. We supply the certification you need, and, more importantly, the backstory behind every line item.

    Lessons Learned From the Field

    We measure impact one shipment at a time. A few years back, a multinational dye producer reported unexplained performance drops in their signature product. After joint trace analysis, the culprit was a trace byproduct linked to outdated filtration media. We helped them adjust, shared our experience switching to a new medium, and both parties improved. In another case, a research group struggled to upscale their process. They traced their problem to inadequate solubility in their solvent system. Following collaborative troubleshooting, we recommended alternative drying stages that minimized inclusions and reduced surface oxidation, resulting in improved reactivity and batch uniformity.

    First-hand knowledge helps field problems before they scale up. We conduct site visits, engage in phone troubleshooting, and send technical support where warranted, translating production data into useable advice. From granular details on solvent compatibility to the impact of packaging on warehouse conditions, these hands-on interventions show the practical role a manufacturer can play beyond mere product supply.

    Environmental Responsibility Starts at the Source

    Modern chemical supply chains bring their fair share of environmental scrutiny. Our processing protocols focus on solvent reuse and closed-loop filtration. We minimize waste wherever possible, returning spent mother liquor for recycling and capturing volatile emissions using state-of-the-art equipment. Disposal occurs only after extensive neutralization and verification. Employees take environmental monitoring seriously, partly because many live near the site and aim to keep their own community safe. Feedback from partner companies informs our efforts; supply agreement clauses now routinely include emissions and waste minimization commitments. We invite external audits and public reporting as part of our transparency initiative, sharing real emissions data in our annual summaries.

    Sustainable sourcing, from energy inputs to packaging, matters to us beyond legal compliance. We introduced reusable pallets and replaced single-use liners, reducing plastic use year over year. Our aim is to drive meaningful progress by being a practical example for the industry—a philosophy strengthened by direct collaboration with like-minded customers and suppliers. This product, while small in quantity compared to bulk chemicals, still carries responsibility, and we aim to set a standard.

    Looking to the Future

    Some people see 4-Amino-3-Nitro-N,N-Dimethylaniline as just another block in the wall of chemical intermediates. For us, it represents decades of improvement, adaptation, and partnership with end-users across the world. The procedural rigor, attention to handling, and commitment to fair dealing echo through each order shipped. We learn from failures, push boundaries on customization, and seek every opportunity to improve, both for our customers and for our own team.

    As research disciplines evolve—integrating new digital tools, automation, and sustainability challenges—the role of the manufacturer transforms as well. We serve as both supplier and technical partner, standing ready to adapt formulations, packaging, or even documentation practices to meet emerging science and industry demands. The journey stretches beyond compound purity into the landscape of technical support, regulatory adaptation, and collaborative innovation. One drum at a time, one problem solved after another, we continue to build a story where trust, technical depth, and transparent communication matter most.

    Final Thoughts: A Grounded Approach Makes the Difference

    Years on the production line, working side by side with staff trained from the ground up, shape our perspective. 4-Amino-3-Nitro-N,N-Dimethylaniline may fill a specific technical slot in manufacturing dyes, sensors, pigments, or diagnostics, but the quality, reliability, and adaptability built into every batch reflect genuine willingness to listen, learn, and improve. Customers turning to us for their supply do not get boilerplate answers or fixed solutions—they get engagement, honest feedback, and a tangible commitment to ongoing improvement.

    In a changing world, those small details—from powder flow to packaging closures, from traceability in sourcing to real-world technical support—set a product apart more than a catalog page of specifications or regulatory text ever will. The lessons earned in daily practice, from one lot to the next, pose the standard to which we hold every shipment. For us, 4-Amino-3-Nitro-N,N-Dimethylaniline is a product shaped not in theory, but in action, through the hands and insight of those who craft it and those who trust it in their own work.