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4',7-Dimethoxy-5-Hydroxyisoflavone

    • Product Name 4',7-Dimethoxy-5-Hydroxyisoflavone
    • Einecs 629-478-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    762096

    Cas Number 57386-18-0
    Iupac Name 5-hydroxy-4,7-dimethoxy-3-phenyl-4H-1-benzopyran-4-one
    Molecular Formula C17H14O5
    Molecular Weight 298.29 g/mol
    Appearance Yellow solid
    Melting Point 238-241°C
    Solubility Slightly soluble in water, soluble in organic solvents such as DMSO and ethanol
    Pubchem Cid 83137
    Smiles COC1=C(C=C(C=C1)OC)C2=COC(=O)C3=CC=CC=C3C2O
    Chemical Class Isoflavone

    As an accredited 4',7-Dimethoxy-5-Hydroxyisoflavone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical 4',7-Dimethoxy-5-Hydroxyisoflavone is packaged in a 1-gram amber glass vial, sealed for protection.
    Shipping 4',7-Dimethoxy-5-Hydroxyisoflavone is shipped in securely sealed, chemical-resistant containers to prevent contamination and degradation. It is packed per regulatory standards, including appropriate hazard labeling. The shipment is handled with temperature control if required, and a material safety data sheet (MSDS) is included for safe transport and handling compliance.
    Storage Store **4',7-Dimethoxy-5-Hydroxyisoflavone** in a tightly sealed container, protected from light and moisture. Keep at room temperature or as specified by the supplier, ideally in a cool, dry, and well-ventilated area. Avoid exposure to incompatible substances and ensure the storage area is labeled and secure, following standard laboratory safety protocols for chemical storage.
    Application of 4',7-Dimethoxy-5-Hydroxyisoflavone

    Applications of 4',7-Dimethoxy-5-Hydroxyisoflavone in Industrial Manufacturing

    As an experienced manufacturer specializing in 4',7-Dimethoxy-5-Hydroxyisoflavone, we focus on real-world industrial use cases where this distinctive isoflavone is directly incorporated as an active ingredient or intermediate. The following sections outline established, high-value downstream applications within pharmaceuticals, nutraceuticals, and specialty chemical synthesis, structured to provide production-focused guidance for formulation, quality compliance, and finished product development.

    1. Pharmaceutical Active Ingredients (API) – Hormonal Modulation Agents

    Pharmaceutical companies source 4',7-Dimethoxy-5-Hydroxyisoflavone as a critical component in hormonal modulation drug development, particularly for products intended to support menopausal health or estrogen-related therapeutics. During production, QC teams confirm standardized purity and monitor for specific isomer ratios to meet stringent pharmacopoeia specifications before formulating it with other actives or excipients. Downstream processes leverage its molecular stability under elevated temperatures during granulation or tablet pressing, ensuring performance consistency in oral dosage forms.

    Industry compliance standards

    • United States Pharmacopeia (USP) standards
    • European Pharmacopoeia (Ph. Eur.) monographs for isoflavones
    • Good Manufacturing Practice (GMP, ICH Q7)
    • FDA 21 CFR Part 210/211 for finished pharmaceuticals

    Typical usage ratio

    • 0.5% – 2.0% w/w in API blend, optimized based on target pharmacokinetic outcome and regulatory labeling restrictions

    Downstream process integration

    • Direct blending with microcrystalline cellulose in wet granulation or dry blending steps prior to tablet compression
    • Inclusion during controlled crystallization for solid dosage form uniformity

    Final product types

    • Prescription hormone balancers (oral tablets, film-coated tablets)
    • Standardized isoflavone supplement capsules for clinical use
    • Adjunct pharmaceuticals targeting menopausal symptom relief

    2. Nutraceuticals – Functional Ingredient in Women’s Health Supplements

    Leading nutraceutical producers incorporate this isoflavone into formulations focused on bone density, cardiovascular health, and hormonal balance in adult women’s dietary supplements. Strict source documentation and batch traceability support consumer and regulatory transparency. During product development, the ingredient integrates with other bioactives—often in encapsulation or matrix blending—where the stability against humidity and light proves critical in preserving claimed bioactivity through the shelf life.

    Industry compliance standards

    • FDA 21 CFR Part 111 (Dietary Supplement GMPs)
    • EFSA Novel Food Catalogue and Food Supplements Directive 2002/46/EC
    • Japan Food Sanitation Act for food additives
    • Quality and safety testing according to ISO 17025

    Typical usage ratio

    • 10 mg – 40 mg per serving, adjusted by regional regulatory allowances and clinical trial benchmarks

    Downstream process integration

    • Addition post-micronization for direct filling in hard shell capsules or sachets
    • Blending with excipients for direct compression in chewable or effervescent tablets

    Final product types

    • Menopausal support capsules and softgels
    • Bone health effervescent tablets
    • Multinutrient functional blends for cardiovascular support

    3. Cosmetic Actives – Anti-Aging and Skin Brightening Formulations

    Cosmetic manufacturers use our isoflavone in targeted anti-aging creams and serums aimed at improving skin elasticity, firmness, and photoprotection. Documentation supports product claims through ISO-tested stability and clinical batch validation. Ingredient integration takes place following precise dispersion either into the oil phase for emulsions or aqueous gels during the controlled cooling stage to prevent oxidation and ensure molecular integrity.

    Industry compliance standards

    • EU Cosmetics Regulation (EC) No 1223/2009
    • US Personal Care Product Council INCI guide
    • China NMPA safety assessment for cosmetic raw materials
    • ISO 22716 Cosmetic GMP Certification

    Typical usage ratio

    • 0.05% – 0.3% w/w, titrated for clinical claim substantiation and dermal patch test safety margins

    Downstream process integration

    • Homogenization into the oil or aqueous phase prior to emulsion formation for creams
    • Suspension within clear gels or hydrogel matrices at the final cooling stage

    Final product types

    • Anti-wrinkle facial serums
    • Skin-firming emulsions
    • Photoprotective moisturizing creams
    • Spot-correcting brightening gels

    4. Specialty Chemicals – Biochemical Synthesis Intermediate

    Specialty chemical and contract manufacturing organizations procure this raw material as a key intermediate in the synthesis of next-generation bioactive molecules, including advanced isoflavone derivatives for research and pilot plant scale-up. The material enters synthesis streams under precision-controlled reaction environments, where its methylated and hydroxylated groups serve as functionalization sites for further derivatization or coupling reactions, demonstrating high yield and purity retention.

    Industry compliance standards

    • ISO 9001:2015 Quality Management System for chemical manufacturing
    • REACH Regulation (EC 1907/2006) for European markets
    • Globally Harmonized System (GHS) for safe handling and labeling
    • Responsible Care and environmental compliance documentation

    Typical usage ratio

    • Professionally defined based on target molecule yield, typically 1:1 to 1:3 molar ratio in the core synthesis batch

    Downstream process integration

    • Initial charge into the reaction vessel for regioselective methylation, acylation, or coupling steps
    • Multi-step reaction integration with subsequent purification, crystallization, and isolation phases

    Final product types

    • Derivatized isoflavone reference standards
    • Specialty building blocks for new drug research (clinical pre-formulation)
    • Research-grade biochemical compounds
    Free Quote

    Competitive 4',7-Dimethoxy-5-Hydroxyisoflavone prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    4',7-Dimethoxy-5-Hydroxyisoflavone: A Closer Look at a Specialized Isoflavone

    Innovation from Start to Finish

    Every batch of 4',7-Dimethoxy-5-Hydroxyisoflavone tells our story as chemical manufacturers who personally handle each step of production, from starting raw materials to packaging the final product. Over years of hands-on experience with flavonoid compounds, our technical teams have honed both the method and the mindset required to deliver a material that meets strict research and industry standards. In our own laboratories, purification and testing aren’t optional steps; they’re how we confirm each shipment matches the identity and purity required for the most sensitive applications.

    Production Insights and Quality Emphasis

    Among isoflavones, 4',7-Dimethoxy-5-Hydroxyisoflavone stands out. Its crystalline solid form and high purity make it a preferred choice for advanced research and development projects. From designing the synthetic route to isolating the precise product, our engineers monitor all reactions and intermediate steps, avoiding shortcuts that would compromise consistency. In our quality control area, advanced chromatographic and spectroscopic methods—developed in-house—reveal not only the purity but also the low-level trace impurities that competitors with generic approaches often miss. We never rely on old specifications; each lot earns its certificate with real, current tests.

    Model and Specifications

    Our current model of 4',7-Dimethoxy-5-Hydroxyisoflavone (CAS number: 1278-51-3) demonstrates reproducible results across scales. Crystalline material arrives as off-white to pale yellow powders, free-flowing and offering stable shelf-life under recommended storage. Many users notice that our homogeneity and batch-to-batch reliability give them the ability to scale research or production without having to recalibrate their processes. This is no accident. Through tight control of reaction conditions, we keep water content, residual solvents, and non-target impurities in check, with analytical data confirming identity by both NMR and HPLC. Purity frequently exceeds 98%.

    Application in Research and Industry

    Chemists and pharmacologists who select this compound often focus on its distinct methoxy and hydroxy substitutions. These groups change solubility, metabolite profile, and reactivity compared to simple isoflavones. Our compound has carved out a place in academic research, particularly in enzyme modulation, antioxidant pathway studies, and pharmaceutical intermediate work. Others pursue it as a probe for plant-derived bioactives or as a lead for synthesis by selective derivatization. We know these specialties inside and out because we frequently collaborate with university and private sector groups, advising on handling techniques and sharing experience to save time and avoid surprises.

    Practical Differences Compared to Other Isoflavones

    Not all isoflavones behave the same way in the lab. 4',7-Dimethoxy-5-Hydroxyisoflavone resists rapid degradation under ambient conditions—years of handling similar materials taught us which isoflavones oxidize too easily or absorb moisture. Small changes in substitution pattern have big effects on extraction, dissolution, and processing in solid-phase or liquid-phase systems, which explains why some research groups struggled until switching to our consistently produced material. Unlike some analogs, our product shows enhanced solubility in organic solvents without the clumping or settling that wastes time and money. This stems from careful drying and close attention to milling techniques during manufacture.

    ISO-Certified Processes—What That Really Means

    A lot of chemical companies display ISO certifications, but behind the curtain, variability still creeps in. We view these standards as minimums, not targets. Often, an improved method discovered in our pilot plant moves into full production quickly. Analytical reports arrive within hours of finishing each batch, not days after, so the finished product doesn’t sit in limbo awaiting uncertain final approval. Regulatory agencies have inspected our site and walked through our batch records more than once. They saw for themselves that our commitment to traceability and reproducibility goes deeper than anything on a certificate or brochure.

    Supporting Advanced Scientific Inquiry

    Many leading research teams come to us when commercial sources don’t meet requirements, or when unfamiliar byproducts appear. Our experience has shown that slight process tweaks—temperature holds, extra purification cycles—often make the difference between a product that works and one that frustrates. We rarely find that so-called isolated products from smaller shops match our uniformity. The constant feedback loop from our customer base keeps us at the cutting edge, guiding improvements in how we purify, package, and ship 4',7-Dimethoxy-5-Hydroxyisoflavone worldwide. Once, a collaborator in Europe shared their difficulties achieving consistent results from a reseller’s blend; within months, our single-source batches solved the puzzle for them.

    Novel Features: Not Just Paper Claims

    Some claim any isoflavone can substitute for another in basic research. Decades working in fine chemicals proved otherwise. The 4',7-dimethoxy and 5-hydroxy pattern shifts polarity and interaction with biological targets, meaning generic materials simply don’t substitute in screening assays, bioavailability studies, or as chiral building blocks. Our in-house chemists routinely run side-by-side comparisons of isoflavones, tracking everything from solubility to melting point to in vitro reactivity. For example, we observed this compound remains stable in buffered solutions under conditions that degrade similar molecules, which offers tangible time and cost savings to our clients.

    Reliability Across Applications

    Beyond research, our product supports industry—organizations developing nutraceuticals or semi-synthetic pharmaceuticals demand never-changing quality. Because we handle every lot from raw material to packed drum, we have the insight to troubleshoot process deviations before material ships. Some customers feed 4',7-Dimethoxy-5-Hydroxyisoflavone directly into multi-step syntheses; for them, uncontrolled impurities mean expensive rework and batch loss. Learning from manufacturing missteps long ago, our teams put in redundancy at each critical phase, like backup filtration and automated moisture checks. These behind-the-scenes efforts make the difference between an interrupted operation and an effortless one.

    Continuous Improvement Through Practice and Partnership

    Part of our role as manufacturers involves staying out front of emerging demands and methods. Serving custom synthesis and new research calls for rapid adaptation. We upgrade instrumentation, review process control logs, and maintain open channels with our users. Routine isn’t complacency: we revisit methods, tweak parameters, and validate improvements with real-world feedback. Once, when a formulation group requested smaller particle sizes, our process engineers tested several milling protocols and shared comparative data. As a result, we added a fine-mill stage for several clients’ lots, reducing dissolution time and increasing overall yield.

    Packaging Learnings Over Time

    Supplying fine chemicals involves more than production—poor packaging can undo days of careful synthesis. Over years of shipping worldwide, we saw how temperature swings, moisture ingress, and transit shocks impacted appearance and recovery. Our solution: choose packing materials based on compound sensitivity and climate, not cost. We double-seal all hygroscopic materials, add fresh desiccant, and use tamper-evident outer containers. Strong labeling, including lot number and full traceability info, comes straight from our records. With these measures, users report material arriving in the same condition as it left our facility, no matter the season.

    The Reality of Custom Requests

    Some projects demand 4',7-Dimethoxy-5-Hydroxyisoflavone at scales or purities not commonly supplied elsewhere. While many resellers turn away such requests, our in-house synthesis capacity handles both pilot and full-scale demands. Our flexible infrastructure allows quick scale-up or scale-down. Meeting tight timelines became second nature—from bench grams for a university lab to multi-kilogram lots for pharmaceutical firms. Open communication means that if a stability or solubility concern emerges, our technical teams speak directly with the end-user, not through intermediaries. This feedback makes us sharper and more responsive than suppliers who never get their hands dirty.

    Safety and Environmental Responsibility

    Decades in chemical manufacturing teach a company that sustainable processes matter as much as end product. We adopt waste minimization strategies at each stage. Solvent recovery, recycling, and emissions controls aren’t checkboxes—they’re ingrained in daily routines. We document every stage of waste handling in accordance with global requirements and local standards. Most importantly, our people work with 4',7-Dimethoxy-5-Hydroxyisoflavone daily, so we invest in regular safety training, ventilation upgrades, and new monitoring equipment. Our processes evolve to lower exposure risk and minimize environmental impact, supporting both our team and the community.

    Sharing Real-World Experience with Users

    Not every researcher or manufacturer has time or resources to develop isolation protocols or troubleshoot unknown byproducts. Our teams regularly share practical advice: best solvents, effective filtration media, optimal temperatures, and storage advice based on years of actual practice rather than theoretical guidelines. This extends far beyond printed instructions. We’ve visited customer labs, hosted technical webinars, and published case studies featuring tricky applications where a real-world solution made the difference. If a customer faces an issue, odds are we’ve navigated something similar before. This is how trust builds, one batch at a time.

    Change, Challenge, and a Look Ahead

    Our industry doesn’t stand still. New research trends, regulatory shifts, and shifting global supply chains mean adaptation is always underway. We revisit our 4',7-Dimethoxy-5-Hydroxyisoflavone process yearly, seeking safer reagents, higher yields, and greener steps. Sometimes that means retiring a trusted method in favor of a better one. These upgrades come from real-world pressure, not marketing slogans. Feedback from global partners flows right into everyday manufacturing. The compound we deliver today reflects decades of experience, active listening, and continuous learning.

    Partnering with Purpose

    Each unit shipped connects us with people searching for precision, reliability, and partnership in a complex field. Our ongoing mission as a manufacturer is to offer more than raw material; we aim to supply assurance, continuity, and shared know-how. Over time, these practices set our 4',7-Dimethoxy-5-Hydroxyisoflavone apart from a sea of commodity offerings. Researchers, synthesists, and production engineers recognize that the details—how a compound is made and supported—directly shape their own success.

    Conclusion Is Unnecessary—Our Product Speaks in the Results It Delivers

    We continue to refine everything from sourcing to shipment with one goal: letting our customers focus on discovery, production, or analysis, never on uncertainty about what’s in the bottle. 4',7-Dimethoxy-5-Hydroxyisoflavone stands as a testament to practical expertise, direct engagement, and a commitment to do things right without cutting corners. Every lot leaving our facility reflects the pride and responsibility that come from building chemicals the right way, from inside the industry itself.