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HS Code |
628053 |
| Chemical Name | 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine |
| Cas Number | 219905-45-8 |
| Molecular Formula | C16H10Cl2N4O2 |
| Molecular Weight | 377.19 |
| Appearance | White to off-white powder |
| Melting Point | 179-181°C |
| Solubility | Slightly soluble in DMSO, insoluble in water |
| Purity | Typically ≥98% |
| Storage Conditions | Store at 2-8°C, protected from light |
| Synonyms | Dichloro-methoxyphenoxy bipyrimidine |
| Smiles | COC1=CC=CC=C1OC2=NC(Cl)=NC(Cl)=C2C3=NC=NC=C3 |
| Inchi | InChI=1S/C16H10Cl2N4O2/c1-24-12-4-2-3-5-13(12)25-15-11-14(17)21-16(18)22-15-10-19-6-8-20-9-7-10/h2-9,11H,1H3 |
As an accredited 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Packaged in a 25-gram amber glass bottle, clearly labeled with chemical name, hazard pictograms, and storage instructions for laboratory use. |
| Shipping | 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine is shipped in sealed, chemical-resistant containers, clearly labeled and securely packaged to prevent leaks or contamination. Standard transport guidelines for laboratory chemicals apply. The shipment complies with relevant regulations (DOT, IATA, IMDG) and includes safety documentation such as the Safety Data Sheet (SDS) for safe handling and emergency response. |
| Storage | Store **4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine** in a tightly sealed container, in a cool, dry, and well-ventilated area away from incompatible substances, such as strong oxidizers or acids. Protect from light, moisture, and direct heat sources. Handle under an inert atmosphere if sensitive to air or humidity. Clearly label the container and ensure appropriate spill containment measures are in place. |
Applications of 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine in Industrial Manufacturing4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine is a specialized intermediate widely used in agrochemical synthesis, particularly as a building block for selective herbicides. Our production and supply focus on the needs of major chemical processing sectors, including large-scale crop protection compounds, fine chemical intermediates, advanced research reagents, and patent-protected synthesis routes for high-value agrochemicals. We maintain strict quality and compliance controls throughout all applications, adapting technical grade and purity specifications to specific manufacturing end uses. 1. Herbicide Active Ingredient SynthesisGlobal crop protection manufacturers incorporate this compound as a core synthetic intermediate in the production of selective post-emergence herbicides targeting broadleaf weeds and grasses. Its unique chemical structure enables stepwise chlorination and etherification reactions critical to the assembly of pyrimidine-class herbicide molecules. Our product maintains consistent reactivity and impurity profiles, supporting high-yield transformations under controlled temperature and solvent conditions typical in bulk herbicide API plants. Industry compliance standards
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2. Pyrimidine-Based Fine Chemical IntermediatesSpecialty fine chemical manufacturers rely on this raw material to construct advanced pyrimidine scaffolds for downstream use in chemical research and laboratory-scale pilot plants. Its highly substituted structure supports nucleophilic substitution, Suzuki coupling, and ring-expansion chemistries developed for bespoke functional molecule synthesis. Production batches undergo strict trace impurity and stability control for advanced chemical R&D and innovation projects. Industry compliance standards
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3. Agrochemical Patent Synthesis Route OptimizationLeading agrochemical R&D centers utilize this compound in the optimization of patent synthesis protocols. Its controlled reactivity and substitution pattern facilitate late-stage diversification of candidate herbicidal compounds, supporting innovation for intellectual property filings and experimental batch scale-up. Continuous feedback on purity, batch consistency, and formulation compatibility helps researchers to minimize process variability and maximize downstream patent value. Industry compliance standards
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4. Custom Synthesis for Agricultural Chemical ResearchSpecialty laboratories and contract synthesis providers employ this substance for the targeted preparation of analogs tested in mode-of-action and resistance studies. Its precise dichloro-methoxy framework makes it essential for generating structure-activity relationship (SAR) datasets, supporting large-scale field trial development and commercial agricultural chemistry rollout plans. We supply research-purity and technical-grade lots to meet varied experimental criteria and analytical method demands. Industry compliance standards
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Every year on the production floor, our team crafts tons of active ingredients that farmers trust for resilient harvests. Among these, 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine stands out for us, not only for its technical difficulty but also for its practical value across the market. Most growers never see the powders or crystals delivered in bulk containers, but for our operators and chemists, the process begins long before the first spray tank mixes or the first weeds curl under the sun.
The two pyrimidine rings linked by a phenoxy bridge create challenges in both synthesis and scale-up. These are not textbook reactions. From the raw chlorinated pyrimidine feeds, every lot that moves through our reactors takes precise heat control, careful solvent management, and patient crystallization. Workers keep a close watch on impurity profiles—trace unreacted intermediates or swapped chlorine positions can threaten an entire batch. At every step, from solvent extraction to drying, the human eye and trusted instruments cooperate to guarantee that each kilogram arriving at a formulator’s tank offers high purity and consistent appearance.
We manufacture this compound as a fine, off-white to pale-yellow solid. On a good run, purity does not wander far from the upper nineties, and water content stays below half a percent. Any supplier can talk about clean analysis numbers or matching the common technical standards. What matters more: how easy it handles for downstream customers. Larger particle blends often resist dusting, but can run into trouble with slower dissolution; ultra-fine lots flow smoothly in automatic systems but require tighter control during transport and blending. Over the years, our production depends on feedback from both international formulators and local blenders to strike a balance—never simply what is cheapest or easiest for shipping, but what avoids real-world mixing headaches at factories and job sites.
Units of this compound fuel herbicide products found on farm supply shelves in dozens of countries. The molecule’s bipyrimidine backbone attracts attention for selectivity, working against broadleaf weeds while sparing the primary crop. Control in the field is judged by results, not advertisements or spec sheets. Formulators choose this active because it dissolves well with oil-based emulsifiers, carries stability through hot storage seasons, and maintains potency in diluted formulations. Design teams designing new product lines want an active that tolerates a wider pH range and mates well with additives. There are plenty of active ingredients in our warehouse, yet few that have served in so many branded recipes, both for pre-emergence and post-emergence weed control.
In the chemical business, shelves rarely sit empty of alternatives. Some actives cost a little less; others pack different regulatory baggage or shelf lives. 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine offers a number of practical edges:
In our plant, consistency never comes by accident. There are easier products to make, and we have plenty in our portfolio. This one requires seasoned labor, not only for reaction setup but for troubleshooting the quirks that naturally crop up as the order book shifts. During long summer runs, humidity can sneak into storage tanks or drying rooms. Operators slow down lines, bleed extra nitrogen, or change silo priorities on short notice. It is not some faceless automation ticking boxes, but real people lifting, blending, and adjusting runs on the fly. Training the next generation in these habits protects the quality level that customers expect over the years.
Authorities set strict rules for active ingredients destined for agriculture, from manufacturing emissions to trace impurity controls. Regulations may shift, sometimes with little advance warning, as the science on groundwater fate or non-target species develops. Over time, consumer pressure and data force improvements—safer waste handling, more efficient water scrubbing, better containment of vapor and dust. The process brings heavy investment, both in hardware and real technical know-how, but also delivers a cleaner product that passes regulatory hurdles across the globe. Our environmental team regularly audits effluents and emission points, catching problems before they ever become compliance concerns. Every time a new regulatory limit appears, the lab teams race to adapt synthesis parameters, update testing methods, or modify packaging for safer handling.
Recent years saw container shortages, unpredictable customs slowdowns, and sudden price jumps for key inputs. As a maker—not a distributor—we weather the squeeze differently. In practice, holding deep stocks of starting reagents often kept lines running when others waited for ships. Having our own drying, milling, and packaging lines lets us respond quickly when a key customer alters a spec or asks for a faster turnover. There were days when operators worked double shifts to rescue late contracts; others when a utility outage forced delayed dispatches. We do not hide behind distant warehouses or virtual agents; face-to-face troubleshooting, both onsite and in the field, builds real trust and gets future orders.
Not all chemicals treat people equally. Though this molecule functions safely for labeled uses, production involves real risks. Flammable solvents, chlorinated intermediates, dust in the air—these shape daily routines in our facility. Workers attend rigorous training sessions; safety gear is standard long before regulatory deadlines arrive. Occasional minor incidents—nicked gloves, a heaved drum, clogged scrubbers—lead to new protocols. Years spent on the line breed an attitude of double checks: “Better a late order than a missing finger.” Our company culture values this; we stick with the hands-on teams who deliver quality and look out for one another.
Trust does not rise from slogans or sales pitches; it grows one shipped order at a time. Repeat formulators keep coming back after their QC teams confirm the same batch results year after year. Some have conducted audits, tracking everything from dock to warehouse; others ask to see dust controls, water samples, or accident records. We do not hide poor runs, and we do not push product out the door simply to fill this quarter’s targets. Years spent in the chemical trade have convinced us: Doing right by long-term customers beats churning a higher volume of one-off deals.
No two markets run on the same calendar or face the same challenges. Some buyers demand larger lots for large-scale pre-emergence blends; others require fine-milled active for small-batch tank mixes in specialty crops. The required regulatory paperwork may differ wildly—one region insists on specific residue data, another on detailed environmental fate summaries. Our export team works in step with on-the-ground compliance experts to ensure smooth customs clearance and support after the first containers land. Small delays compound into missed growing windows, so rapid response to paperwork changes or shipment reroutes builds loyalty overseas as surely as chemical purity at home.
Making a dependable active ingredient starts in the plant, but innovation comes from the lab. Process chemists continually explore greener synthesis routes, lower solvent usage, and alternative reagents to cut waste or reduce hazardous byproducts. Some of our runs now employ solvent recycling loops that recovered thousands of liters last year alone, shrank disposal burden, and helped cut costs straight to the customer. Our research teams tack on more stability trials in response to customer feedback; new packaging formats—like moisture-tight bags or custom palletization—result from requests overseas. It’s a cycle: plant veterans raise production pain points with the science team, and new bench trials feed back improvements for the next run. From top management to apprentice operators, everyone has a stake in making each lot just a notch better than the last.
Rumors occasionally rise that all actives might someday be imported; few see the value in skilled hands and local supply. Our decades of in-house experience with this compound say otherwise. Years invested in direct supervision, in-house troubleshooting, and hard-won lessons in process control pay off when quick pivots or sudden quality challenges appear. Machines help, but they cannot replicate a foreman’s judgement on a borderline filtration setting or a technician’s nose for contaminated solvent. Holding control at every link—from raw material reception through loading onto outbound trucks—lets our team catch problems earlier and deliver a level of consistency unmatched by hands-off bulk resellers.
Few end-users realize the work behind a kilogram of high-purity 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine. Distributors want seamless paperwork; formulators want reliable delivery windows; end-user blenders need predictable performance. We open regular communication channels, from real-time lot tracking to technical bulletins on best handling practices. When a blender in another country reports a solubility issue in a new formulation, our technical team investigates causes—particle size spread, unexpected dusting, or temperature variance. Adjustments may lead us to tweak a drying profile for an upcoming lot or suggest changes in the downstream formulation. These dialogs build a partnership—not just a vendor-buyer relationship.
Every batch we ship carries heavy responsibilities. Used carelessly, actives can harm more than target weeds, threaten worker safety, or drift to nontarget crops. The science on resistance management shapes how, and how often, these molecules should be deployed. We contribute to stewardship research efforts, supply detailed label update guidance, and respond quickly to question from regulators or advocacy groups. It is not about polishing public image; it comes from knowing that real people work and live where our products are used, just as real hands make those same products back in our factory.
Every chemical plant faces generational turnover. Veteran operators train newcomers to recognize real-world danger signs—strange reactor noise, odd dust patterns, the subtle chemical odors that precede a runaway reaction. Chemistry degrees matter, but practical instruction turns theory into safe, profitable operation. Our senior chemists take pride in sparking curiosity, not just compliance, among the new recruits. Across small towns and industrial districts, these jobs bring stability and reputation. Being able to tell a neighbor that the product in their hands came directly from our crew carries weight.
As pressure grows to feed more people with fewer resources, the world’s farms depend on practical, reliable chemistry. 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine keeps fields clean and yields high when applied in line with the best agronomic and stewardship practices. Our goal goes beyond just meeting today’s orders. We adapt to evolving field needs, shifting environmental standards, and new resistance threats, always with a focus on integrity, safety, and an open channel to end users. In every ton dispatched, our manufacturing team sees more than product—we see the trust placed in us, and the responsibility to deliver on every promise made, batch by batch, season after season.