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4,6-Diaminoresorcinol Dihydrochloride

    • Product Name 4,6-Diaminoresorcinol Dihydrochloride
    • Alias DAR·2HCl
    • Einecs 241-231-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    702065

    Chemical Name 4,6-Diaminoresorcinol Dihydrochloride
    Synonyms 1,3-Dihydroxy-4,6-diaminobenzene dihydrochloride
    Molecular Formula C6H10Cl2N2O2
    Molecular Weight 213.07 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 280-285°C (dec.)
    Solubility Soluble in water
    Cas Number 14516-71-3
    Purity Typically ≥98%
    Storage Temperature Store at 2-8°C
    Hazard Class Irritant
    Hs Code 29222990
    Boiling Point Decomposes before boiling

    As an accredited 4,6-Diaminoresorcinol Dihydrochloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging contains 25 grams of 4,6-Diaminoresorcinol Dihydrochloride, sealed in a clear, labeled amber glass bottle with safety cap.
    Shipping 4,6-Diaminoresorcinol Dihydrochloride should be shipped in tightly sealed, chemical-resistant containers to prevent moisture absorption and contamination. It must be clearly labeled and handled according to applicable regulations for hazardous substances. During transit, store in a cool, dry place away from incompatible materials, with appropriate documentation and safety data included with the shipment.
    Storage 4,6-Diaminoresorcinol Dihydrochloride should be stored in a tightly closed container, in a cool, dry, and well-ventilated area. Protect it from light, moisture, and incompatible materials such as strong oxidizing agents. Store at room temperature (15–25°C) and handle with suitable personal protective equipment. Ensure proper labeling and keep away from sources of ignition or heat.
    Application of 4,6-Diaminoresorcinol Dihydrochloride

    Applications of 4,6-Diaminoresorcinol Dihydrochloride in Industrial Manufacturing

    As a direct manufacturer, we supply 4,6-Diaminoresorcinol Dihydrochloride for several critical industrial sectors where its precise functional properties enable consistent production performance. Each application scenario below reflects the compound’s real-world use in specific manufacturing segments, with focused information on compliance, formulation, processing, and final product output.

    1. High-Performance Hair Dye Intermediate Manufacturing

    Leading personal care producers utilize this material in permanent oxidative hair dye systems to enhance color depth and shade stability. Manufacturers select it as a primary precursor for brown and red tones due to its specific reactivity with coupling agents and oxidizers during the coloring process. The raw material enters the dye precursor stage, where it must achieve both batch-to-batch color uniformity and long-term stability under consumer use conditions.

    Industry compliance standards

    • EU Cosmetic Regulation (EC) No 1223/2009 Annex III–Directive for Hair Dye Substances
    • U.S. Food and Drug Administration (FDA) 21 CFR Part 73 (Color Additives)
    • China National Medical Products Administration (NMPA) Cosmetic Safety Technical Standard
    • ISO 22716: Good Manufacturing Practices for Cosmetics

    Typical usage ratio

    • 0.05–0.2% w/w in the finished dye cream; actual ratio tailored based on target color intensity and formulation type (cream, gel, or liquid systems)

    Downstream process integration

    • Added during the intermediate stage of dye formulation, before final mixing with coupling agents and oxidizing agents; ensures full solubilization and reaction completion prior to viscosity adjustment and packaging

    Final product types

    • Permanent hair coloring creams
    • Professional salon hair dye kits
    • Ready-to-use oxidative dye formulations for home use

    2. Advanced Monomer Synthesis for Polyamide Engineering Plastics

    This compound supports the specialty polymer industry as a valued diamine monomer, particularly where high-temperature and chemical resistance are essential. It acts as a building block in aromatic polyamide (aramid) and specialty polyimide resins, integrated via polycondensation reactions to support structural integrity in technical plastics for electronics and automotive components.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for Resin Manufacturers
    • REACH Regulation (EC) No 1907/2006 for Chemical Registration
    • RoHS Directive (EU) 2015/863 for Electrical/Electronic Applications
    • UL 94 Flammability Testing for Plastics

    Typical usage ratio

    • 5–15 mol% of total diamine component, ratio depends on target polymer backbone rigidity and desired glass transition temperature

    Downstream process integration

    • Directly charged into the polycondensation reactor alongside aromatic tetracarboxylic dianhydrides and other diamines; dissolved and reacted at elevated temperature in aprotic solvents such as NMP or DMAc

    Final product types

    • High-strength composite fibers
    • Precision-molded technical parts for automotive/electronics
    • Dielectric films for flexible printed circuits

    3. Analytical Reagent Production for Spectrophotometric Assays

    Specialty chemical manufacturers employ this compound in the preparation of diazo-coupled reagents used in analytical chemistry, particularly for colorimetric detection kits. Its well-defined redox properties and diazotization activity support accurate measurement of trace metals in water and biological samples, entering the blending step for laboratory-grade diagnostic reagents.

    Industry compliance standards

    • ISO 17034 Reference Material Producer Accreditation
    • ISO 9001:2015 for Analytical Reagent Production
    • OECD Good Laboratory Practice (GLP) for Test Kits
    • US EPA Methods for Wastewater Analysis

    Typical usage ratio

    • 1–5 mg/L as working concentration in finished test solutions; prepared as 0.1–1% w/v stock solutions for certified test kit production

    Downstream process integration

    • Introduced at reagent blending and solution compounding step; undergoes filtration and QC batch testing for analytical sensitivity and specificity before final bottle filling

    Final product types

    • Colorimetric water testing kits
    • Trace metal (e.g., iron, copper) assay reagents
    • Laboratory reference solutions for spectrophotometry

    4. Pharmaceutical Intermediate for Active Pharmaceutical Ingredient (API) Synthesis

    The pharmaceutical sector uses this raw material as a selective building block in multi-step synthesis of certain API precursors, notably for compounds with complex aromatic amine scaffolds. Entry occurs during early-stage functional group transformations—specifically reductive amination or coupling—for regulated manufacture of approved drug substances, where trace impurity control and analytical verification are mandatory.

    Industry compliance standards

    • Good Manufacturing Practice (GMP) per ICH Q7A and EU GMP Guidelines
    • Pharmacopoeial compliance: USP, EP, JP as required by the target API
    • FDA Registration of Drug Establishment
    • ICH Q3A Impurity Profile Standards

    Typical usage ratio

    • Stoichiometric, based on reaction mechanism; 1.0–1.2 molar equivalents in relation to core starting material, optimized for yield and minimal side-reaction

    Downstream process integration

    • Added at the designated step for aromatic amine introduction, frequently under controlled reduction or condensation conditions; followed by intermediate purification and analytical checks for trace-level consistency

    Final product types

    • API precursor intermediates
    • Final drug substances compliant with international pharmacopoeias
    • Regulatory filing reference samples for clinical evaluation
    Free Quote

    Competitive 4,6-Diaminoresorcinol Dihydrochloride prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 4,6-Diaminoresorcinol Dihydrochloride: Precision in Every Batch

    Our Approach to Manufacturing 4,6-Diaminoresorcinol Dihydrochloride

    Manufacturing 4,6-Diaminoresorcinol Dihydrochloride is a journey we know first-hand, forged through years of refining process control and learning what matters for users building end-products that cannot afford surprises. This compound, known among chemists as 4,6-diamino-1,3-benzenediol dihydrochloride, plays a unique role in specialty synthesis, dyestuff development, and high-purity pharmaceutical intermediates. Time after time, we’ve seen demand tighten around the need for both chemical purity and reliable consistency. That is where our plant focuses resources, not only in specification but also in real manufacturing discipline.

    Model and Specifications: Beyond Labels and Numbers

    Every lot leaving our line holds a minimum purity of 99%. We track moisture content, ash, and heavy metal residue as an integral part of daily QC. Rigorous batch sampling ensures no lot stands apart from the next in appearance or reactivity. This strict adherence pays off where mishandled or off-spec chemicals would cause run batch failure downstream—something we refuse to tolerate in our site. As for form, our 4,6-diaminoresorcinol dihydrochloride presents as a free-flowing crystalline powder, with hue and tactile feel closely monitored because appearance often flags subtle quality issues in our experience. We maintain a standard mesh size to aid users during formulation, thought out through customer feedback and in-house trials.

    Using Experience to Anticipate User Requirements

    Researchers and manufacturers face tight regulatory scrutiny and economic pressure. We work closely with users involved in API synthesis, pigment formulation, and functional material R&D. Over multiple years, we’ve been told that the issue isn’t only theoretical purity. It’s batch-to-batch reproducibility, solubility in relevant solvents, and absence of troublesome contaminants that ruin valuable syntheses. So, manufacturing takes on a hands-on character for our team. Reactor temperature windows are monitored for spike detection, purification steps double-checked with both in-process HPLC and endpoint analysis. For users scaling up, receiving material that behaves identically every time reduces validation headaches and keeps costs in check.

    Where 4,6-Diaminoresorcinol Dihydrochloride Stands Out From Other Intermediates

    Plenty of aromatic amine compounds exist, yet working with 4,6-diaminoresorcinol dihydrochloride brings specific advantages. Its symmetrical aminated positions on the resorcinol core allow for targeted downstream modifications difficult with many less substituted analogues. Chemists value its ability to act as both an intermediate and a building block for certain pharmaceutical agents and molecular dyes. Our ongoing collaborations with partners indexing their formulation against our material confirm that minimizing side-products in production dramatically reduces downstream purification. The ease-of-handling and solubility profile also set this compound apart from ortho- or para-aminated resorcinol derivatives, which often behave unpredictably or bring higher toxicity.

    We’ve also worked through the common obstacles others in the industry face with commercially available grades. Some suppliers blend or cut material for color uniformity, introducing hidden impurities. Others leave behind organochloride residues or have inconsistent drying protocols, resulting in variable yields. Years of investing in our crystallization and drying facilities prevent the cake formation or caking seen in poorly handled material, allowing for direct use straight from the packaging.

    Practical Use Cases Our Team Coordinates With Users

    4,6-Diaminoresorcinol dihydrochloride often plays a vital role in building up specialty dyes for fiber and film coloring. Pigment chemists using our product highlight how much it helps when every variable is controlled. When downstream color strength and reproducibility matter, minor contaminants mean wasted material and repeat runs—so our focus always circles back to keeping byproduct formation from our line at a practical minimum.

    The pharmaceutical sector frequently relies on this material, especially as a coupling component or protected intermediate for more complex nitrogen-heterocyclic drugs. Scale-up teams in active pharmaceutical ingredient production tell us that skipping further pre-purification steps, thanks to our higher isolation purity and absence of unreacted parent aniline derivatives, saves energy and time. Even outside pharma, we’ve tracked long-term customers developing specialty hardeners or thermoset resins, where a consistent supply of this compound supports process specifications and material certifications.

    Our Insights on Supply Quality Versus Market Norms

    Price pressure runs high, and so naturally does the temptation for producers to take shortcuts. As longtime chemical manufacturers, we’d rather scrap a batch than let a shipment leave that jeopardizes anyone’s process. Working with 4,6-diaminoresorcinol dihydrochloride, contamination sources—particularly by nitro-resorcinol or incomplete reduced species—require sharp process oversight. We address this not just by tightening raw material sources, but also by investing in redundant final purification. For us, customer claims and post-shipment inquiries drop sharply when we continuously audit real-user complaint reports and add their feedback back into our standard operating procedures.

    We have fielded many calls from teams burned by poorly manufactured batches from unknown traders and generic resellers. These situations often play out with downstream batches being ruined by color drift, trace solids clogging lines, or API regulatory submissions failing because the impurity spectra no longer conform to drug master files. Our longest-standing major customer partnerships grew out of stepping in to resolve these problems, not with marketing claims, but with data-sharing and line-by-line QC audit support.

    Learning From Feedback: Balancing Process Safety and User Demands

    Safety in production receives heavy attention in our plant owing to the dangers of aromatic diamine chemistry. We learned—often through hard lessons early on—that maintaining proper exhaust, neutralization, and personal protection protocols does not only protect our team; it preserves the product’s purity as well. Worker cross-contamination or lax area cleaning contribute directly to trace impurities or unexpected reactivity issues. Our production line always operates under strict zone separation, and all personnel undergo rotating batch-signoff to catch protocol drift before it cascades into quality failures.

    User pushback led us a few years ago to re-examine drying cycles to improve the handling characteristics of this material under humid production sites, directly addressing the “clumping” complaint from dye blenders and formulators. Not all production issues resolve easily, and over-drying led us to recalibrate standard specifications following several large-customer process validation runs. Every workaround adds practical insight to manufacturing, and that experience then guides our batch criteria.

    Environmental and Compliance Considerations

    Most chemical makers know the real work begins with regulatory compliance. 4,6-diaminoresorcinol dihydrochloride sits under multiple oversight regimes in key jurisdictions. We never take REACH, TSCA, or FDA guidance lightly, especially given the risk of underestimating impurity carry-over or exposure impact. Our records stay open to customer audit, and we retain batch samples for extended periods for traceability. This is more than paperwork: it directly affects the trust our customers can claim in their own audits and product file submissions.

    Several years ago, an unexpected regulatory change forced us to bring additional heavy-metal impurity tracking into our analytical template. Rather than scrambling with crisis-station fixes, our team built in analytical redundancies, targeting iron, copper, and lead at low ppm levels throughout our QA workflow. Customer processes, especially for food-contact or pharma applications, now benefit from this, having a much clearer risk profile to present to their stakeholders or boards.

    Partnership Mindset: Sharing Knowledge, Building Trust

    Our years in chemical manufacturing show that transparency does more than reduce headaches for our supply partners—it builds loyalty. Before most shipments, we discuss user process requirements and integration plans. For pharmaceutical supply, we even arrange joint analytical method validation, cross-comparing our in-house validated results with the customer’s own process chromatograms. For pigment or specialty resin formulators, we talk through charging order, solvent compatibility, and packaging preferences, so when the time comes to open a drum, there’s no guesswork or lost time.

    We acknowledge that unexpected issues sometimes emerge. Solvent selection for dissolution, changes in regulatory interpretation, or even weather-influenced logistics can catch even seasoned teams off-guard. Our technical team pursues root-cause analysis, not just for internal learning, but for proactivity with user updates. For example, a recent distribution challenge due to excessive summer humidity in a major market drove us to trial multiple inner liner materials. A simple switch to a more robust, multi-layer liner cut on-site clumping by over 80%, as shown from user-submitted storage and handling evaluations.

    Comparing to Other Manufacturing Approaches: A Closer Look

    Chemists sometimes ask us what distinguishes our 4,6-diaminoresorcinol dihydrochloride from competitors’ versions beyond published purity specs. Our answer draws from our first-hand batch history. Some competitors chase overnight cycle throughput, pushing reductions and oxidations faster at the cost of trace by-products. We deliberately hold process times longer to run QC in real time, catching early departures from target product before they affect an entire lot. Others allow broader impurity windows, banking on downstream user purification. We see this as inefficient and a false economy; most downstream users have no interest in reworking what should be a clean feedstock.

    The advantages also extend into packaging and delivery. Over the years, we trialed several types of vessel and liner combinations at our partners’ request, paying attention to how different user sites handle drum opening or product dispensing. Chemists and operators reported fewer dusting accidents, simpler integration into process steps, and reduced waste with our chosen format. In our own evaluation, these refinements brought down return requests and made bulk use more predictable, easing compliance with occupational safety standards.

    Problems and Continual Solutions: An Open Dialogue With Users

    Every chemical production line faces setbacks—sometimes an unpredictable raw material batch, supplier delays, or a process parameter drift. What distinguishes a committed manufacturer is not spotless records, but immediate attention and forthright communication. Not long ago, a major pigment producer identified a drop in dye consistency and traced it to upstream contamination not picked up by standard testing. Instead of shifting blame, our team added an extra purification step, shared the full investigation, and supplied additional test data to allow their own labs to cross-check. The outcome: a stronger process for both of us, trust won, and a practical template for future troubleshooting.

    We keep improving our analytical methods. Techniques like LC-MS, elemental analysis, and new forms of spectroscopy aid in mapping trace compounds. If a new impurity appears—whether through regulatory tightening or user findings—we build it into our QC flow and update product certificates. We involve the user in analytical transitions, never assuming lab changes are just for our internal scorecard. Shared understanding beats top-down policy every time.

    What The Future Looks Like for 4,6-Diaminoresorcinol Dihydrochloride Manufacturing

    Chemical manufacturing no longer resembles its past. Demands climb for cleaner, safer, and more transparent supply. 4,6-Diaminoresorcinol dihydrochloride production illustrates how small process changes—switching a purification solvent, modifying a pH window, or improving drying technique—produce outsized impacts for users all the way through application and final product approval. We see not just a market for a product, but a platform to learn from every delivered batch. Each customer partnership teaches us more, and that ends up in every lot, every drum, and every shared process note.

    Above all, our promise stands: what leaves our line matches more than an internal document. Over years, chemists, engineers, and plant operators taught us the value of accountability. Our batch history, hands-on process refinements, and ready openness shape what it means to supply 4,6-diaminoresorcinol dihydrochloride that just works—for daily synthesis, for mission-critical production, for moving our industry into the next chapter with confidence.