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HS Code |
497701 |
| Chemical Name | 4,5-Dicyano-2-Aminoimidazole |
| Molecular Formula | C5H3N5 |
| Molecular Weight | 133.11 g/mol |
| Cas Number | 94496-68-9 |
| Appearance | Off-white to light brown powder |
| Melting Point | Decomposes >300°C |
| Solubility | Slightly soluble in water; soluble in DMSO and DMF |
| Purity | Typically ≥98% |
| Storage Conditions | Store at 2-8°C, protected from light and moisture |
| Iupac Name | 2-amino-1H-imidazole-4,5-dicarbonitrile |
| Synonyms | 2-Aminoimidazole-4,5-dicarbonitrile |
| Smiles | N#CC1=NC(=N[C@H]1N)C#N |
As an accredited 4,5-Dicyano-2-Aminoimidazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The packaging for 4,5-Dicyano-2-Aminoimidazole (5 grams) is a sealed amber glass bottle with hazard labeling and product identification. |
| Shipping | 4,5-Dicyano-2-Aminoimidazole is shipped in tightly sealed containers to prevent moisture ingress and contamination. Packaging complies with chemical safety regulations, typically using inert, non-reactive materials. Proper labeling, documentation, and handling instructions are included, and shipments are transported according to national and international hazardous materials guidelines to ensure safe delivery. |
| Storage | 4,5-Dicyano-2-Aminoimidazole should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. Store at room temperature and protect from moisture and light. Use only non-sparking tools and minimize dust generation to avoid inhalation. Proper labeling and secure storage are essential. |
Applications of 4,5-Dicyano-2-Aminoimidazole in Industrial ManufacturingOur production of 4,5-dicyano-2-aminoimidazole supports specialized chemical synthesis workflows across various sectors. We engage directly with manufacturers who require highly selective intermediates for complex downstream reactions, especially where purity and traceability must meet strict international standards. Below, we detail key application domains where this raw material plays a critical, process-specific role. 1. Pharmaceutical Heterocycle SynthesisPharmaceutical companies use 4,5-dicyano-2-aminoimidazole as a core building block for synthesizing advanced heterocyclic scaffolds, particularly in research and commercial routes involving anti-infectives and oncology drug APIs. Manufacturers typically introduce this intermediate in early-stage cyclization or condensation steps, benefiting from its controlled reactivity to construct target molecular frameworks while maintaining stringent impurity profiles as demanded by regulatory authorities. Industry compliance standards
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2. Agrochemical Active Ingredient SynthesisProducers of crop protection molecules incorporate this intermediate in the manufacture of systemic fungicides and selected insecticide actives. The unique cyano-imidazole structure enables the formation of stable heterocyclic systems, which functionalize downstream to deliver molecules with target-specific environmental resistance, essential for registered agrochemical formulations. Each manufacturing campaign requires rigorous mass balance documentation for regulatory inspections. Industry compliance standards
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3. Electronic Materials—Semiconductor IntermediateSemiconductor chemical manufacturers employ 4,5-dicyano-2-aminoimidazole for synthesizing highly conjugated organic compounds, especially precursors for electron-transport layers and advanced photoresist systems in IC fabrication. The compound’s electron-withdrawing structure imparts desirable charge-carrier mobility properties necessary for developing high-purity thin films used in OLED displays and other organic electronics. Quality assurance in these processes mandates tight control over trace metal content and residual impurities. Industry compliance standards
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4. Fine Chemical Intermediate for Colorant ManufacturingManufacturers specializing in dye and pigment synthesis use 4,5-dicyano-2-aminoimidazole in the production of high-performance pigment molecules and specialty dyes. Its reactivity supports the formation of nitrogen-rich chromophores, with downstream products widely used in textile coloring, inkjet cartridges, and performance coatings. Strict batch-to-batch consistency and regulatory documentation on trace impurities are essential throughout scale-up and commercial production. Industry compliance standards
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5. Specialty Polymer Monomer SynthesisSpecialty polymer manufacturers incorporate this intermediate when designing copolymer systems requiring tailored electronic or thermal performance, such as in advanced engineering plastics or membrane technologies. The molecule’s unique functional groups enable controlled copolymerization and site-specific backbone modifications, which are critical for applications involving precise mechanical or filtration properties. Entire process batches undergo documented traceability and monomer conversion efficiency testing prior to product release. Industry compliance standards
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We have been engaged in the manufacture of specialty imidazoles for years, and 4,5-Dicyano-2-Aminoimidazole stands out in our range. Chemistry is never a field that rewards shortcuts, and this compound takes skillful hands and patient processing. Our line, marked by consistency from batch to batch, shows both the reliability and flexibility that continuous production brings. In the laboratory and on the production floor, workers and chemists prioritize material purity and repeatable behavior, both of which we have refined through thousands of hours of feedback and adjustment around actual customer usage.
4,5-Dicyano-2-Aminoimidazole isn’t a commodity. Its molecular structure, with cyano groups at positions 4 and 5 and an amino at position 2, creates unique electron patterns. That’s something you notice straight away during synthetic work. It demands precision in temperature control and the handling of reactive intermediates. Years ago, our early production had to contend with variable yields and unpredictable side reactions. Through process improvements and stubborn attention to the details that matter, we brought yields up and lowered the noise in the chromatograms.
The compound’s appearance—fine, free-flowing powder, white or pale off-white—signals successful exclusion of degradation products. Some competitors accept higher levels of colored impurities due to shortcut purifications. We saw customers run into quenching or reproducibility issues. Our technicians applied staged crystallization and adjusted solvent ratios to address that. Today, the difference comes through in end product performance, especially in highly sensitive synthetic steps or assays.
Purity is a measurement of professional pride on the factory line. For 4,5-Dicyano-2-Aminoimidazole, we target minimum purity levels over 98%. Routine batch analytics include HPLC, NMR, and elemental analysis. ‘Routine’ doesn’t mean mindless – each test is an active crosscheck on both method and material. We support analytical transparency, providing traceable batch data to partners. These details matter because small variations in reactivity cost more than a rework: they can ruin week-long syntheses in the hands of customers. Chemists who rely on our 4,5-Dicyano-2-Aminoimidazole to function as a robust building block get precise control over downstream N-alkylation, ring formation, or pharmaceutical intermediate steps.
Some orders demand tighter controls, where residual solvent or water content drops to below 0.5%. We handle that with post-drying and in-line checks, not just spot checks at dispatch. These procedures result from customer requests and real process headaches—not from standard manuals.
Not every molecule has true versatility, but 4,5-Dicyano-2-Aminoimidazole covers a lot of bases in chemical industries. Its cyano groups make it receptive to further modification—essential in medicinal chemistry where stepwise synthesis wins out over one-pot attempts. End-users turn to this compound to build imidazole-based heterocycles, often integrated into pharmaceutical candidates targeting antiviral or anticancer effects. Our ongoing conversations with researchers tell us most value purity and straightforward scale-up over low price. They want to trust outcomes, not gamble on variable quality.
Lab notebooks fill up with its function as a precursor to fused and substituted imidazoles, especially in research around bioactive small molecules. Peptide mimics, kinase inhibitors, and assorted bioassays run on the backbone our compound provides. In specialty polymers and material science, that electron-withdrawing effect from the cyano groups builds performance into dielectric layers and molecular electronics. Some of our largest orders come from material research teams looking to push imidazole derivatives into new functional films.
We also see steady demand from contract research firms and pharmaceutical scale-up facilities. They need kilogram-lot consistency, not gram-scale curiosity. Our plant infrastructure, designed around process safety and dust containment, lets us offer this at practical lead times.
Customers rarely want columns of raw numbers—they want context and trust. 4,5-Dicyano-2-Aminoimidazole leaves our line with moisture and heavy metal levels below the tough standards set by pharmaceutical applications. Packing lines track temperature and exposure; sealed bags reach the loading dock without risk of humidity pickup or cross-contamination. Supply teams deal directly with technical questions about solubility, stability during shipping, and blending for downstream synthesis. We learned years back that answering chemistry questions with fact, not jargon, builds real partnerships.
We keep particle size within tight bands, since users blending this compound for solid-phase reactions run into trouble with fines or clumps. Standard mesh readings and bulk density checks make their work easier down the line.
Many companies supply related imidazoles and nitriles. Our customers have told us direct comparisons matter, not specification sheets. 4,5-Dicyano-2-Aminoimidazole stands apart from similar-looking materials such as 2-Aminoimidazole or dicyanoimidazole isomers, both in reactivity and in the way it behaves in multistep syntheses. The double cyano substitution changes more than shelf stability; it shifts both nucleophilicity and the activation energy required for downstream reactions. Chemical process teams who tried less-substituted or mixed isomer imidazoles often ran into yield plateaus or unexpected byproducts. Our conversations with process engineers pointed to the need for uniformity, low side-product profiles, and robust scale-up support.
We deliver a product ready for either bench-top proof-of-concept or pilot-scale optimization. Older sources, especially from single-step or batch importers, can show high variability or lack detailed analytical support. Our controlled environment and history of ‘living in the trenches’ of plant-scale chemistry led us to rule out shortcuts. This lets process chemists rely on set stoichiometry and avoid re-developed workups from lot to lot.
Chemical production always raises questions about safety and repeatability, and 4,5-Dicyano-2-Aminoimidazole is no exception. This compound, with its cyano groups, asks for experienced containment and exhaust protocols. Years back, we experienced fugitive emission problems during a process scaleup; that lesson burned in procedures for granular dust control, tailored ventilation, and regular re-training. We work with regulators, not just for compliance but because trust falls apart if downstream users face exposure or cross-contamination.
We also invested in closed-loop waste management for water and spent solvents. Every kilo produced reflects the feedback loop between what plants need, what regulators demand, and what operators learn by doing the work. Our own teams carry out ongoing risk analyses not as an annual box to tick but as a weekly review, often response to user questions or production surprises.
We learned early on that the best compound in the world is useless if it doesn’t arrive when and where it’s needed. Over the years, we adapted our shipping and storage for 4,5-Dicyano-2-Aminoimidazole to address actual pain points: temperature variation, customs holds, and long-haul transits. Sealed pouches inside hard drums, long shelf-life at ambient conditions, and custom labeling all came from customer feedback rather than from generic guidelines.
Lead times matter to chemists running high-throughput or scheduled scale-ups. Our order system ties plant output directly to scheduling, so we give honest lead times and live updates. Teams at universities, pharmaceutical companies, and industrial research centers want a single batch to last through an entire series. We keep track of repeating orders at the batch level, so each lot matches or improves on the last.
We rarely see two customers with identical applications, but consistency in raw material remains a shared requirement. Every batch receives a unique identification string linked to production logs and analytics. Over the years, our experience showed that hidden batch blending or off-shore tolling creates more customer headaches than it solves. Aligning technical documentation with actual material, not just paperwork structure, builds confidence for audits, regulatory reporting, and in-lab troubleshooting.
Raw data—chromatograms, certificates, analytical spectra—arrive with shipments. Some buyers run confirmation tests; others trust our record. Quality control personnel and regulatory teams have come to rely on full disclosure of trace contaminants as new rules around genotoxic impurities grow stricter. Both large and small firms push for transparency, and we support them from the plant level up.
No process or compound, no matter how refined, escapes ongoing improvement. As analytical expectations rise, so do requests for new grades—chromatography-grade, enhanced stability for long-term storage, or customized particle sizes. Even with many years’ experience, we still run into new questions from the field. Prompt technical support, batch-specific consultation, and follow-up testing close the loop between what goes out the door and how the compound performs in actual use.
In recent years, as more synthetic chemists tackle demanding cross-coupling and ring extension protocols involving 4,5-Dicyano-2-Aminoimidazole, we found that adjustments in bulk density and granulation method could cut downtimes and manual corrections in customer plants. This happened because we listened—not just to procurement teams, but to the chemists who run the reactions. Small improvements, like re-engineering desiccant packs in shipment or changing bag liners, emerged from problem reports, not design committees.
No sales brochure replaces steady, reliable product performance. Researchers and production chemists open bags and load materials with expectations set by years of both good and bad supply experiences. 4,5-Dicyano-2-Aminoimidazole is one of those specialty intermediates that carries disproportionate impact for its size. If it doesn’t meet expectations, whole synthesis flows back up. We take enormous pride in the fact that repeat customers quote yields, track impurities, and note the absence of failed scale-ups directly to our production records, not just catalog entries.
Change in process chemistry is constant. Today’s hot candidate or workflow often shifts seasonally. Because of our long track record supplying 4,5-Dicyano-2-Aminoimidazole, we support discussions around new uses—such as its integration in high-throughput screening or adaptive chemistry platforms. Our technical support does not end at the invoice; every batch delivers a chance to reinforce partnerships by troubleshooting unusual outcomes or tuning parameters for project-specific workflows.
Competition in specialty chemical manufacturing can create pressure for cost-cutting, shortcuts, or imprecise marketing. From years watching the cycles of buyouts, rebranding, and reformulation, we stuck to direct production control for 4,5-Dicyano-2-Aminoimidazole. Process improvements occur in-house, allowing us to update or adapt as both regulatory demands and actual usage shift. Customers feel the difference, not only in product performance but also in the willingness to address questions and act on feedback.
Emerging environmental standards continue to challenge all producers. We integrate waste minimization, solvent recycling, and responsible sourcing of upstream precursors as integral parts of our strategy. This direct engagement with sustainability is not just “greenwashing”—it prevents supply interruptions and earns preferences from buyers facing internal audit.
4,5-Dicyano-2-Aminoimidazole reflects the intersection of technical expertise, persistent improvement, and open communication with end-users. Over years and through thousands of kilograms produced, refined, packaged, and shipped worldwide, we have found that mastery of detail—down to solubility curves, impurity profiles, and shelf life—anchors trust with customers doing demanding research, manufacturing, or product development. The pathway from plant to customer is neither quick nor mechanical, but shaped by operators and chemists committed to material excellence. As technology pushes research into new frontiers, from molecular electronics to innovative medicinal chemistry, we continue strengthening both our process rigor and our engagement with those who rely on our materials to make each new breakthrough possible.