|
HS Code |
586364 |
| Chemical Name | 4-(4-Phenylbutoxy)benzoic acid |
| Cas Number | 38579-93-0 |
| Molecular Formula | C17H16O3 |
| Molecular Weight | 268.31 g/mol |
| Appearance | White to off-white solid |
| Melting Point | 132-135 °C |
| Solubility | Slightly soluble in organic solvents, insoluble in water |
| Purity | Typically ≥98% |
| Storage Conditions | Store at 2-8°C, tightly closed |
| Synonyms | p-(4-Phenylbutoxy)benzoic acid |
| Smiles | C1=CC=C(C=C1)CCCCOC2=CC=C(C=C2)C(=O)O |
| Inchi | InChI=1S/C17H16O3/c18-17(19)14-8-10-15(11-9-14)20-13-7-6-12-16-4-2-1-3-5-16/h1-5,8-11H,6-7,12-13H2,(H,18,19) |
As an accredited 4-(4-Phenylbutoxy)Benzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White, opaque HDPE bottle with tamper-evident seal, labeled “4-(4-Phenylbutoxy)Benzoic Acid, 25g” and safety information in black text. |
| Shipping | 4-(4-Phenylbutoxy)benzoic acid is shipped in tightly sealed containers, protected from light and moisture. It should be handled as a potentially hazardous organic compound, following all standard chemical transport regulations. The package is labeled according to local and international guidelines to ensure safe delivery and compliance with safety standards. |
| Storage | Store 4-(4-Phenylbutoxy)benzoic acid in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, well-ventilated area, away from sources of heat, ignition, or incompatible substances such as strong oxidizers. Clearly label the container and avoid prolonged exposure to air to prevent degradation. Always follow standard laboratory safety and chemical storage guidelines. |
Applications of 4-(4-Phenylbutoxy)Benzoic Acid in Industrial Manufacturing4-(4-Phenylbutoxy)benzoic acid supports specialized production in multiple advanced manufacturing sectors. As an experienced producer, we supply this intermediate directly to leading enterprises that require precise functional properties in organic synthesis, display materials, and pharmaceutical compounds. Below, we detail key application scenarios based on actual industry practice. 1. Liquid Crystal Intermediate for Display Material ProductionThis compound serves as an essential intermediate for synthesizing specific liquid crystal monomers used in advanced display panels, including TFT-LCD and OLED screens. Its unique aromatic structure and chain length contribute to precise phase transition temperatures and thermal stability in nematic and smectic liquid crystal formulations. Major display manufacturers integrate 4-(4-Phenylbutoxy)benzoic acid during the coupling step to achieve tailored birefringence and voltage holding ratios required for high-definition panels. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Pharmaceutical Intermediate for Selective Estrogen Modulator SynthesisThe structure of this compound matches key intermediates required for synthesizing certain selective estrogen receptor modulators (SERMs) and other investigational APIs with aromatic ether groups. GMP-compliant pharmaceutical manufacturers utilize this acid in the early-stage coupling and condensation steps for active pharmaceutical ingredient (API) build-up designed for clinical and veterinary applications. All production follows validated synthetic routes to ensure regulatory clearance and API traceability. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Organic Synthesis Building Block for Plasticizer and Polymer Modifier ProductionIndustrial polymer manufacturers use this compound as a specialty building block to introduce flexible aromatic side chains in functional plasticizers and polymeric modifiers. Its structure enables precise tuning of mechanical and thermal properties in high-performance resins, including polyesters and polycarbonates. Production occurs under continuous feed conditions in reactors designed for large-scale downstream polymer modification. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Specialty Surfactant and Emulsifier Intermediate for Industrial FormulationsSelect industrial surfactant producers incorporate this compound as an intermediate for nonionic and aromatic ether surfactant synthesis. Its aromatic backbone and ether linkage support the formation of stable emulsions in demanding systems, such as metalworking fluids and specialty coatings. Controlled batch processing ensures molecular uniformity and consistent batch-to-batch performance, with dedicated QA on surfactant behavior in finished emulsions. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
|
Competitive 4-(4-Phenylbutoxy)Benzoic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: admin@sinochem-nanjing.com
Flexible payment, competitive price, premium service - Inquire now!
We know our way around the synthesis of aromatic carboxylic acids, and 4-(4-Phenylbutoxy)benzoic acid stands out in our lineup for good reason. We deal with industries and researchers who have an eye for purity and structure, and over the years we have tuned our process to give a product that meets the tightest of project needs. This compound, known for its unique butoxy and phenyl substituents, carries an appeal that extends across the liquid crystal, pharmaceutical intermediate, and material science fields.
There are similar benzoic acids on the market, but our process produces a 4-(4-Phenylbutoxy)benzoic acid that forms the plate-like white crystals every chemist wants to see after a clean recrystallization. Our experience tells us that the presence of both the benzyloxy and the terminal phenyl allows this compound to plug directly into a lot of liquid crystal host matrices. Researchers call out for this exact substitution pattern because the length and bulk of the four-carbon spacer balances fluidity against ordering forces in the critical precursor steps toward complex mesogens and sophisticated optical materials.
We understand what people working in high-precision environments expect. Whether it’s a matter of optimizing transition temperatures for liquid crystals, fine-tuning solubilities in organic syntheses, or creating intermediates that don’t cloud the regulatory picture, each batch we make reflects experience, skill, and relentless attention to detail. Some competitors might overlook subtle isomeric impurity levels, but our methods nail down those key analytic thresholds before we let anything out the door.
Our operation doesn’t just weigh, stir, and collect; we analyze throughout each step, knowing how even minor contaminants can throw off the entire chain of downstream reactions. From the starting phenols through to the alkylation and subsequent carboxylation, we keep tabs on every parameter—solvent loads, reaction times, even the choice of filtration aids in the final isolation. Chromatographic profiles and crystallinity tell us instantly whether we have missed anything meaningful, not just during quality control runs, but as part of the day-to-day workflow.
Other products on the market sometimes display odd off-white tinges or granularity, a sign that precursors or workup protocols haven’t reached the right level. We’re often contacted to troubleshoot materials sourced elsewhere that block up filters or dissolve unevenly. The people working here have seen these issues across years, not just from bench samples but in scaled lots, and our 4-(4-Phenylbutoxy)benzoic acid passes every routine and advanced test we throw at it. Customers usually notice the difference as soon as a sample lands in the lab. It comes down to mindful approaches—recrystallizing from carefully dried solvents, or tracking temperature ramp rates to the decimal through the crystallization point.
We don’t just post a melting point and say the job’s done. For 4-(4-Phenylbutoxy)benzoic acid, we recognize that trace moisture, minor residual solvent, or an overlooked byproduct can mean the difference between a high-clarity polymorphic phase and a hazy sample. Each batch passes through gas chromatography for volatiles and HPLC for trace organics. We track loss-on-drying with calibrated instruments, not simply what a catalog asks for. When our laboratory notes a deviation—even one or two tenths of a percent off the expected mass loss—the whole process gets reviewed, right down to the packaging step. This attention to specifics comes from decades of not wanting to see a batch returned or a client’s project derailed.
Researchers come to us for this molecule because it solves specific bottlenecks in advanced chemistry. In the development of new thermotropic liquid crystal mixtures, its aromatic character combined with the flexible butoxy linker allows designers to dial in melting and clearing points. We’ve interacted with formulators who want precise transition windows for custom display technologies, and every request has driven us to refine our own output. In small molecule OLED and polymer research, this acid often seeds fresh routes to backbone modifications that can’t handle shorter linkers or bulky side chains. It simply behaves more predictably—no unexpected oligomerization, no hidden reactivity.
Pharmaceutical projects often search for these substituted benzoic acids when scaffolding new active pharmaceutical ingredients. The safety, purity, and repeatability we provide are not abstractions; failed scale-ups, patent complications, and regulatory setbacks are very real for our clients. We get calls for documentation and references, but what wins repeat business is the lack of surprises. Every year we see cases where a seemingly minor impurity would pass most standard screens but show up later in stability trials, causing months of setback for an ambitious project. Letting nothing go uncharacterized saves time in places many customers never see.
It’s easy to overlook the small differences between products that share much of their naming structure. We often meet people who have tried other para-alkoxybenzoic acids, thinking one is as good as the next. But the additional phenyl ring in 4-(4-Phenylbutoxy)benzoic acid marks a distinct step up in molecular architecture. Other common materials, such as 4-butoxybenzoic acid or 4-phenoxybenzoic acid, can lack the specific spatial features that let this compound slot seamlessly into more exotic materials. The presence of the four-carbon chain absorbs thermal stress differently, allowing for blends that resist crystallization on cooling, essential in displays and films where phase stability across temperature swings means the difference between working and waste.
Some customers try to swap in simpler alkoxy or aryloxy analogs, but they quickly notice less reliable performance in solvent systems, slow dissolves, or inconsistent results in functionalized polymer synthesis. Lower-molecular-weight analogs tend to crystallize too early, while bulkier groups can wreck the physical properties being targeted in the final application. It’s not just about plugging in another benzoic acid and hoping; it’s about understanding the downstream chemistry. Over the years, we’ve had customers come back after failed attempts with off-the-shelf standards, recognizing that purchasing directly from the original manufacturer brings peace of mind along with the correct grade.
We watch over every step between raw starting materials and finished, packed product. Over time, we’ve seen how seasonal changes, even in humidity or slight shifts in ambient temperature, can affect crystallization and filtration rates. Experience tells us how to slow or speed the cooling, how to judge the end-point of a mother liquor filtration, and when to rework a batch, not just run the numbers. This knowledge has been earned through hands-on learning, scaled-up from a hundred grams to tens of kilos, and this skill shows up every time our material lands on a research bench or production line.
Working directly with our partners, we field technical queries all the time—sometimes about why a previously reliable supplier’s material no longer works in a critical formulation, or how to troubleshoot an unexpected impurity. Often, the issue traces to overlooked details: incomplete drying, surface adsorption of silicates from poor glassware cleaning, or exhausted adsorption beds during solvent purification. None of our competitors can replicate the benefit of a long-running, experienced production team with a focus on this precise family of chemicals.
4-(4-Phenylbutoxy)benzoic acid doesn’t just go out the door with a certificate of analysis; it leaves with decades of experience and troubleshooting behind it. Our team has participated directly in many of the applications it supports, whether by helping during method development for new display technologies, working through scale-up challenges with pharmaceutical partners, or building new platforms for the next round of polymer hybrids. The kind of support we provide goes beyond numbers in a spec sheet.
Every big project, whether in advanced materials or new medicinal chemistry, involves trade-offs and careful material selection. Our product is rarely the result of an off-the-shelf approach—a discussion about polymorph control or optimal recrystallization solvent can reshape how someone tackles a research hurdle. We often help clients stretch their budgets by advising on recovery and reuse practices, or by customizing the packaging and shipment for sensitive processes that dislike repeated air exposure. These details, sometimes small, highlight the importance of working directly with the original manufacturing source, not a faceless distribution chain that can’t field technical questions.
Every batch we manufacture of 4-(4-Phenylbutoxy)benzoic acid brings together years of iterative improvement: switching filtration media after a performance dip, modifying reaction times based on hands-on monitoring of the precipitation, and regular validation of NMR and MS spectra on every lot. Some competitors take the route of accepting “good enough” because demand can be low or variable. We set our standards higher, refining isolation procedures, and documenting changes so that customers receive an identical product regardless of the production date. This diligence pays off in lower project attrition and smoother regulatory scrutiny for our partners, whether running pilot plant studies or preparing investigational new drug dossiers.
Often, research-oriented customers want to know how well one batch will match another across years. The answer comes from not just our analytical records, but also our institutional memory: the same hands mix, observe, and judge each reaction. Unseen details like the selection of a particular solvent grade, or the swap between two seemingly identical water bath controllers, all get recorded and considered. That is not the kind of diligence that comes from a trader. It comes from running a production facility where setbacks are problems to solve, not shipments to reroute.
We serve a diverse clientele, ranging from R&D groups developing experimental compounds to production facilities targeting scalable intermediates. The need for 4-(4-Phenylbutoxy)benzoic acid often emerges when alternative routes produce too many byproducts or when target properties keep drifting. Our response is direct discussion and solution-building, responding to requests for alternate solvents, custom particle size specifications, or incremental purity grade changes. Through close feedback cycles, we maintain high success rates.
The difference is clear when researchers compare our materials to what is purchased through indirect channels. By adjusting batch sizes or purification pathways based on specific requests, we ensure continuity and reliability. Sometimes, these changes appear minor on paper—a shift in drying technique from vacuum to nitrogen flow, or a reoptimization of precipitation from ethanol to isopropanol—but in practice, the difference can reach full project outcomes. Customers working in demanding synthetic environments come back for this reason: predictable, hands-on problem solving, not catalog numbers and shipping updates.
Long-term relationships matter to us. Repeat customers approach us because they value not just the product, but the willingness to stand behind the material. Over the years, these ties help both sides solve bottlenecks faster, handle scale-up needs more confidently, and anticipate changes in the broader supply chain for rare intermediates like 4-(4-Phenylbutoxy)benzoic acid. Technical conversations happen directly with skilled manufacturing chemists, not through layers of salespeople.
A project can rise or fall on a single impurity or on the small but crucial decision to adjust a protocol. By remaining transparent and responsive, we’ve avoided the pitfalls that plague less-engaged sources. When new regulations, safety concerns, or documentation requirements emerge, we adapt quickly, drawing on years of previous audits and third-party verification. Our partners gain not just a batch of chemical, but a partner in progress and innovation.
Interest in 4-(4-Phenylbutoxy)benzoic acid keeps growing, especially as demands rise for higher-specification materials in both academic and commercial research. Our commitment is to evolve with the needs of those on the bench and in the plant, whether through incremental improvements to our internal analytics or targeted expansions in output capacity.
Every improvement we make—automating a key analysis, tightening temperature controls, or enhancing end-of-line particle screening—aims directly at increased safety, higher performance, and more reliable chemistry for advanced creators. Feedback from seasoned researchers and developers matters here, and we never see a batch go out the door without the team knowing the exact end-application context. That’s the advantage of working with a manufacturer who stands behind the entire lifecycle of the product.
4-(4-Phenylbutoxy)benzoic acid, from the perspective of hands-on manufacturing, is much more than a line in a database. It brings together routine, refinement, and responsiveness, grounded both in the chemistry of aromatic acids and in the realities of lab-bench and industrial-scale needs. The problems we solve stretch from the earliest days of a project through to regulatory submission and commercial ramp-up, and each challenge has sharpened our focus on quality, adaptability, and embedded support.
As the pace of material and pharmaceutical development moves ever faster, the compounds at the base of these advances need trustworthy sources and real knowledge in their production. By building relationships, not just transactions, we ensure that every shipment of our 4-(4-Phenylbutoxy)benzoic acid stands for something beyond certification—it supports discovery, reliability, and the practical progress of applied chemistry worldwide.