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4,4'-Oxydiphenol

    • Product Name 4,4'-Oxydiphenol
    • Alias 4,4'-Dihydroxyphenyl ether
    • Einecs 201-944-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    645208

    Chemical Name 4,4'-Oxydiphenol
    Other Names Bis(4-hydroxyphenyl) ether
    Cas Number 1761-19-9
    Molecular Formula C12H10O3
    Molecular Weight 202.21 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 169-171 °C
    Solubility In Water Slightly soluble
    Density 1.32 g/cm3
    Odor Odorless
    Pka Approximately 9.9
    Structure C6H4(OH)-O-(OH)C6H4

    As an accredited 4,4'-Oxydiphenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 4,4'-Oxydiphenol is packaged in a 500-gram amber glass bottle with a secure screw cap and detailed hazard labeling.
    Shipping 4,4'-Oxydiphenol should be shipped in tightly sealed, corrosion-resistant containers, protected from moisture and incompatible materials. It is classified as a hazardous chemical and must comply with relevant transport regulations. Appropriate hazard labeling, safety data sheets, and documentation are required to ensure safe and compliant shipping. Store cool and dry during transit.
    Storage 4,4'-Oxydiphenol should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers and bases. Protect it from light and moisture. Use only non-sparking tools and avoid the formation of dust. Proper labeling and secondary containment are recommended to prevent accidental release or exposure.
    Application of 4,4'-Oxydiphenol

    Applications of 4,4'-Oxydiphenol in Industrial Manufacturing

    As a specialized chemical raw material manufacturer, we support diverse industries with high-purity 4,4'-Oxydiphenol. Our focus spans critical downstream sectors relying on its unique reactivity and structural properties. Below we outline established applications, with practical details on compliance, formulation usage, and downstream integration.

    1. Polyarylene Ether Resin Production

    4,4'-Oxydiphenol is a key monomer in manufacturing advanced polyarylene ether resins, especially polyethersulfone (PES) and polyetheretherketone (PEEK). Producers blend it with dichlorobenzenes under alkali fusion or nucleophilic substitution, leveraging its dihydroxy structure to drive chain extension. Manufacturers require strict control over reaction temperature and monomer purity to ensure the produced polymers meet high strength and thermal performance standards for aerospace, electronic, and automotive applications.

    Industry compliance standards

    • ISO 9001 Quality Management System
    • REACH Regulation (EC) No 1907/2006
    • RoHS Directive 2011/65/EU (for electronics-grade resins)
    • ASTM D6394 for PES resin properties

    Typical usage ratio

    • 20–50% by monomer mass, adjusted according to target molecular weight and final resin properties

    Downstream process integration

    • Monomer blending and dehydration step in the polycondensation reactor, followed by post-polymerization purification and pelletizing

    Final product types

    • High-performance PEEK and PES pellets
    • Glass-fiber reinforced engineering plastics
    • Insulation components for electrical industries
    • Membranes for ultrafiltration and reverse osmosis

    2. Epoxy Resin Hardener Synthesis

    Downstream formulators use 4,4'-Oxydiphenol to synthesize specialty epoxy curing agents, taking advantage of its ortho-dihydroxy phenolic groups. The material enters phenol-formaldehyde condensation routes for novolac-type hardeners and in modified bismaleimide or polyhydroxyamine systems. Consistency in raw material purity is crucial for controlling cross-linking density, reactivity, and chemical resistance in electrical insulation, adhesives, and coatings.

    Industry compliance standards

    • UL 94 Flammability Standards (for electrical applications)
    • IEC 61249-2-21 for halogen-free resins
    • ISO 178 for flexural properties of cured systems

    Typical usage ratio

    • 10–35% by total hardener mass; formulation depends on target cure speed and thermal requirements

    Downstream process integration

    • Addition during the prepolymer synthesis stage prior to blending with epoxy resin; mixing occurs under nitrogen atmosphere to avoid premature cross-linking

    Final product types

    • Epoxy tooling boards
    • Structural adhesives
    • Molded electrical encapsulation compounds
    • Protective coatings for printed circuit boards

    3. Synthesis of UV Absorbers for Plastics

    Manufacturers leverage 4,4'-Oxydiphenol in the synthesis of benzotriazole and benzophenone derivatives used as UV absorbers and stabilizers in plastics. This application requires precision in molecular modification and fine-tuning of reaction conditions to prevent by-products that could impact the optical clarity or color stability in high-transparency polymers. The stabilizers serve in rigid and flexible PVC, PET, and polycarbonate formulations.

    Industry compliance standards

    • FDA 21 CFR 178.2010 (for indirect food contact in plastics)
    • EN ISO 4892-2 for artificial weathering testing
    • ISO 14001 Environmental Management (waste control in synthesis)

    Typical usage ratio

    • 0.1–2% as a comonomer or additive precursor, set by UV stability required in the final plastic product

    Downstream process integration

    • Used in the first chemical synthesis step for manufacturing UV absorber intermediates; subsequently isolated, purified, and compounded into plastic masterbatches

    Final product types

    • Outdoor weatherable films
    • Aerospace polymer components
    • Cosmetic packaging
    • Automotive lighting covers

    4. Intermediates for Antioxidant Additives

    Production of hindered phenol antioxidants utilizes 4,4'-Oxydiphenol as a main starting material for dialkylated phenolic structures. The process involves alkylation and esterification, with strict monitoring of product purity and residual phenol content. The antioxidants formulated help control polymer oxidation and extend service life for specialty lubricants, thermoplastics, and elastomers processed in high-shear or high-temperature environments.

    Industry compliance standards

    • OECD Test Guidelines 301 for biodegradability
    • FDA 21 CFR 178.3570 (lubricant antioxidant use)
    • ASTM D4676 for antioxidant performance in polyolefins

    Typical usage ratio

    • 0.05–0.5% based on total polymer or lubricant mass, tuned to application temperature and exposure conditions

    Downstream process integration

    • Alkylation at the initial stage to form dialkyl phenol, followed by esterification to final antioxidant; blending into base oils or polymer resins during compounding

    Final product types

    • Polyolefin plastic granules for packaging films
    • High-performance synthetic lubricants
    • Polyurethane foams and coatings
    • Electrical cable insulation materials

    5. Dye Intermediate Manufacturing for Specialty Colorants

    4,4'-Oxydiphenol serves as an essential intermediate in synthesis routes of azo and anthraquinone dyes, notably those requiring high fastness and chromatic stability. The synthesis typically includes diazotization, coupling, and oxidative cyclization steps. Quality control prioritizes residual unreacted phenol and chromophore development, as downstream customers require precision for color matching in textiles and high-spec inks.

    Industry compliance standards

    • ETAD GMP for colorant materials
    • OEKO-TEX Standard 100 (for textile dyes)
    • ISO 105-C06 for wash fastness testing
    • EU REACH Annex XVII for restricted amines and heavy metals

    Typical usage ratio

    • Varies by dye class, commonly 15–40% in the intermediate synthesis batch, with adjustments based on desired color intensity and solubility

    Downstream process integration

    • Introduced in the diazotization or condensation step; intermediates purified and supplied as powders or dispersions to finished dye makers

    Final product types

    • Reactive and disperse textile dyes
    • Specialty inkjet printing inks
    • Automotive and industrial coatings
    • High-performance plastic colorants

    6. Photographic Chemical Synthesis

    Producers of color photographic developers utilize 4,4'-Oxydiphenol as a core reducing compound in the synthesis of certain color developer agents. The production process involves ethylation or sulfonation of the base material under controlled conditions, delivering high reactivity while minimizing impurity carryover. Final agents must meet strict photograde specifications for use in film and paper processing solutions.

    Industry compliance standards

    • ISO 9001 (photographic chemical QC)
    • Photographic Activity Test (ISO 18916)
    • ANSI/NAPM IT9.17 for photographic image stability

    Typical usage ratio

    • 10–25% in developer intermediate syntheses, precise dosage set by formulation for developer strength and image tone

    Downstream process integration

    • Sulfonation or alkylation in primary reaction vessel, followed by refining and crystalline isolation; agents supplied to film and paper process chemical plant lines

    Final product types

    • Color developer solutions for analog film
    • Photographic paper developers
    • Color stabilization agents
    • Automated photofinishing system concentrates
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    Certification & Compliance
    More Introduction

    4,4'-Oxydiphenol: Real Performance for Demanding Processes

    From Reaction Vessel to Final Product: Our Approach to 4,4'-Oxydiphenol Manufacturing

    Every batch of 4,4'-Oxydiphenol tells a story of chemistry on the shop floor—mixed, purified, and checked for consistency in our own facilities. Over the years, we have fine-tuned each step to produce material that holds up under the pressures of industrial use. Here, the emphasis falls on quality you can actually verify in the lab and on the line. Our engineers and technicians know where bottlenecks arise, what impurities disrupt downstream applications, and what customers face when things stray from spec.

    Model selection for 4,4'-Oxydiphenol should rest on usage requirements, not marketing gloss. Some applications in liquid crystal displays or high-performance epoxy resins demand exceptionally high purity and rigorously low metal content. Others, including antioxidant production or polymer intermediates, might tolerate broader specifications. We manufacture several grades, with clear labeling and documentation, so plant managers can match lots to their exact needs. Our high-grade 4,4'-Oxydiphenol often achieves purity above 99% by HPLC, with water and residue rigorously minimized after multiple-stage crystallization and filtration. Each batch runs through repeatable, independent assays for any elements that might compromise sensitive reactions—days before product ever leaves our warehouse.

    How 4,4'-Oxydiphenol Fits Into Real-World Chemistries

    We often see engineers reach for 4,4'-Oxydiphenol during the synthesis of specialty polymers. Its symmetrical biphenolic structure bridges two phenol rings via an ether linkage, enabling reactivity that more basic phenols cannot match. This ether bond stands up to more aggressive conditions and fosters crosslinking or extension in polymer backbones, all while preserving electronic stability. In epoxy systems, it anchors rigidity and enhances thermal performance—proven by improved glass transition temperatures and reduced yellowing under load. Small changes in material structure translate into real gains in end-use properties. Several coating plants send feedback about reduced off-gassing during cure and steadier color profiles over multi-year weathering cycles, especially when compared to alternatives like hydroquinone or resorcinol.

    Users in the field describe 4,4'-Oxydiphenol’s impact in resin modification, dye manufacturing, and antioxidant formulations. In dyes, the phenolic groups unlock routes for azo and quinone synthesis, giving designers more freedom over chromophore architecture. We have seen pigment manufacturers shift toward our higher-purity grades to eliminate batch-to-batch drift in their spectral curves. Rubber additive formulators add this compound for its ability to donate hydrogen and scavenge radicals, lengthening the useful life of elastomers exposed to ozone or high heat.

    Standing Apart from Similar Phenolics

    Not all phenolic intermediates serve the same function once batches scale up. 4,4'-Oxydiphenol shares family ties with hydroquinone, catechol, and bisphenol A, but its chemistry unlocks unique opportunities—some of which become apparent only after repeated runs in diverse plant environments. Where 4,4'-Oxydiphenol outperforms hydroquinone usually centers on the rigidity and spacing introduced by the ether bridge; this spacing reduces unwanted side reactions and lets resin networks develop with predictability and less discoloration over repeated thermal cycles. Against catechol or resorcinol, its symmetry and spacing limit uncontrolled branching and random crosslinks, a feature that appeals to electronic materials makers pursuing stable dielectric properties.

    Our production controls double-check for trace metals and organic byproducts—details that might seem minor until they pop up as conductive points or gels in circuits and coatings. In our experience, customers from the electronics sector are quick to highlight the difference clean, predictable 4,4'-Oxydiphenol makes when compared to lesser-purified phenolic intermediates. A recent project with a display manufacturer confirmed that line performance—conductivity stability, color retention, and defect rates—improved measurably when sub-ppm iron and copper were confirmed by post-delivery analyses of our product.

    Field-Driven Adjustments and Technical Flexibility

    Rarely does one batch resemble the last in terms of technical hurdles. Customers call us after discovering that even a modest uptick in trace chlorinated byproducts can foul catalysts, slow polymerizations, or skew product color. Instead of generic troubleshooting, our plant operators, with years of hands-on lab and vessel work, communicate directly with process chemists to pinpoint source issues. For certain markets, we adapted our final purification to strip out chlorides below detection limits, and we selectively adjust our crystallization protocols to bring sodium and potassium readings lower when required. Many producers do not invest in regular, real-world technical dialogue about these issues, but having the infrastructure on hand gives us tools for rapid response—no need for slow overseas handling or circuitous communication through agents.

    Our experience extends beyond shipping bulk drums. We help formulators predict impact on viscosity, color, and chemical resistance based on small shifts in specification. Repeat users in adhesives and coatings routinely ask for side-by-side samples of standard and low-metal-content grades before contract renewals. This level of support became especially important as regulatory bodies worldwide grew stricter around contaminants in electronics, food packaging, and pharmaceuticals. By running additional in-house analyses, we give our partners confidence in meeting legislative requirements without added paperwork or sourcing delays.

    Consistency, Reliability, and the Real Costs of Downtime

    The disruption caused by inconsistent raw materials rarely makes headlines, but it creates hidden costs in manufacturing. An unplanned plant shutdown, a ruined reactor load, or delivery delays from poorly controlled intermediates can throw off schedules for months. We learned from hard experience that taking shortcuts with quality checks—skipping a chromatography run, glossing over trace contaminant tests—inevitably costs more time and money than careful, routine verification. Every 4,4'-Oxydiphenol lot we release into the supply chain reflects these lessons.

    Consistent product only emerges from continuous investment in process improvements. We replaced several legacy components in our purification system after supervisors and customers reported subtle shifts in material performance under high-temperature application. Instead of relying on external auditors or annual upgrades, our operators handle control charts weekly, tweaking flows and conditions to hit the same performance benchmarks each time. Feedback from partner labs and real user workplaces keeps these controls relevant, not theoretical. This approach minimized deviations and made our lots interchangeable for most users—cutting the risk of line revalidation or unnecessary retesting.

    Product Safety Without Red Tape

    Chemical safety never runs on autopilot, particularly with phenolic intermediates with known toxicity risks. Our own staff carries out routine hazard assessments, sharing any new handling protocols when risk data or workplace conditions change. We supply carriers and storage partners with the exact recommendations that come from practical, day-to-day movement through our facility—not just from manufacturer literature or international guidelines. As a manufacturer that regularly stores bulk lots, we install spill mitigation and ventilation that exceeds regulatory minimums because we know the chaos a poorly contained phenolic spill causes for an entire production wing.

    Our training covers not only product storage and movement, but also addresses common human errors—like hastily capped containers or unscheduled maintenance during transfer. Over the years, several customers have requested on-site walkthroughs or shared video documentation of their handling procedures, eager to improve. Rather than brushing off concerns or referring back to generic documentation, our team records their suggestions and incorporates feedback into future batches, whether that means resizing packaging for easier transfer or updating labels with distinct hazard indicators.

    Environmental Responsibility in Practice

    Actual manufacturing demands a practical environmental approach, not just aspirational policies. Phenolic intermediates, including 4,4'-Oxydiphenol, can create waste streams that complicate both treatment and compliance. Regulations have tightened worldwide, so we outfitted our plants to neutralize effluent through multi-stage treatments and frequent in-process monitoring. Where solvents are used, we recycle at the highest possible rate, balancing efficiency against product integrity. By keeping a close eye on all waste sources from extraction to purification, we reduce environmental risk and keep documentation easily accessible during partner audits or inspections.

    It is not enough to simply “meet standards.” Our internal audits track water usage, emissions, and byproduct generation in real time, flagging deviations for immediate response. Over the past few years, we reduced solvent consumption per finished kilogram by more than 20 percent after reorganizing our extraction lines and switching to closed-loop recovery systems. Some byproducts, previously routed straight to disposal, now feed secondary processes, generating additional value and reducing landfill contributions. These changes came about through consistent tracking and a willingness to adjust methods, not external pressure.

    Learning from Customer Challenges

    Each time we supply to a new end market, our teams try to understand the actual performance goals and potential pitfalls. In polymer films, even minor discoloration or off-odor can tank an entire production run. For electronics, polymer stability means the difference between failure in a circuit and millions of units passing quality checks. We have walked lines with operators in several regions, watching firsthand the effects of temperature, humidity, and batch consistency on their results. Reports from these plant floors guide the ongoing tweaks in our own processes, such as modifying storage times, humidity controls in packaging, or transport scheduling during peak climate swings.

    Customer-driven trialing brings surprises. One user flagged final product caking attributed back to minor shifts in particle size distribution caused by seasonal temperature changes during transit. Instead of dismissing it, our production and shipment teams revised conditioning and container selection—a solution that would have gone unnoticed without open technical feedback. These experiences build trust and reduce repeat troubleshooting in future deliveries.

    Balanced Innovation and Open Communication

    Experienced manufacturers balance measured innovation with proven practices. Novel purification routes allow us to push for lower impurities and better reproducibility, but not at the expense of plant safety or reliable delivery. Regular collaboration with end-users, quality assurance labs, and academic partners ensures our technical development keeps pace with realistic industrial demands. While the chemical structure of 4,4'-Oxydiphenol stays fixed, our methods and protocols adapt as markets and applications mature.

    Direct, jargon-free communication shortens learning cycles. Whether a customer seeks clarification for a new regulatory requirement or wants a run-down of how temperature swings affect storage, we provide clear, practical guidance. With each partnership, we gather feedback that sharpens our focus—highlighting which material attributes matter most across insulation, paints, adhesives, or specialty chemicals. This culture of transparency stems from seeing firsthand the costs of misaligned expectations and miscommunications between manufacturing and user sites.

    Supporting Research and Next-Generation Applications

    The reach of 4,4'-Oxydiphenol grows as new technologies emerge. Researchers have begun using it as a building block for advanced polymers with tailored conductivity, stability, and resistance profiles. Our facility often works with university and industrial groups, providing small-lot samples and supporting data as they design and test the next generation of molecular architectures. Such partnerships bring new insight into material behavior, reinforcing our own product standards and guiding process improvements.

    Research often uncovers variables that only surface after extensive pilot runs and prototype testing. For instance, a university project exploring biocompatible polymers encountered unanticipated catalyst sensitivity to trace byproducts; after sharing chromatographic findings, we adjusted purification on subsequent lots, improving yields and reducing experimental runs. Partnerships like these keep us accountable to both academic rigor and commercial practicality, allowing the chemical to reach its full potential in future markets.

    The Case for Domestic Production

    Tightened global logistics and rising transportation costs have highlighted the value of experienced, responsive domestic manufacturing. As a producer, we can respond nimbly to sudden market shifts, supply disruptions, or rapid changes in regulatory expectation—without the extended lead times or uncertainties often encountered with imported intermediates. By maintaining full control over formulation, inventory, and technical support, we shield our customers from many common industry challenges. Reliable supply, tested by years of engagement with demanding process sectors, distinguishes us in a landscape often dominated by brokers and offshore suppliers.

    We take pride in the direct accountability that comes from producing 4,4'-Oxydiphenol under our own roof. Here, each batch is born from a combination of hands-on expertise, technical discipline, and meaningful collaboration with those who depend on consistent quality for their own manufacturing success.