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4-(4-Methoxyphenyl)-1-Butanol

    • Product Name 4-(4-Methoxyphenyl)-1-Butanol
    • Alias p-Methoxyphenylbutanol
    • Einecs 615-095-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    271819

    Chemical Name 4-(4-Methoxyphenyl)-1-Butanol
    Molecular Formula C11H16O2
    Molar Mass 180.25 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 310-312°C
    Density 1.03 g/cm3
    Refractive Index 1.522
    Solubility In Water Slightly soluble
    Smiles COC1=CC=C(C=C1)CCCCO
    Cas Number 22627-32-3
    Purity Typically ≥98%
    Flash Point 140°C
    Storage Conditions Store at room temperature, keep tightly closed

    As an accredited 4-(4-Methoxyphenyl)-1-Butanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4-(4-Methoxyphenyl)-1-Butanol is supplied in a sealed amber glass bottle with a tamper-evident cap and hazard labeling.
    Shipping 4-(4-Methoxyphenyl)-1-Butanol is shipped in tightly sealed containers, protected from light and moisture. It must be packaged according to local and international chemical shipping regulations, clearly labeled, and accompanied by a safety data sheet (SDS). Handle with appropriate precautions to avoid spills or contact during transportation. Store at recommended temperature upon arrival.
    Storage **4-(4-Methoxyphenyl)-1-Butanol** should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, away from sources of ignition, strong oxidizers, and incompatible substances. Ensure labels are clear and containers are stored at room temperature or as specified by the supplier’s safety data sheet (SDS).
    Application of 4-(4-Methoxyphenyl)-1-Butanol

    Applications of 4-(4-Methoxyphenyl)-1-Butanol in Industrial Manufacturing

    As a direct manufacturer of 4-(4-Methoxyphenyl)-1-Butanol, we support a diverse range of industrial sectors that require precise molecular customizations. Below, we describe key downstream application areas, providing detail on compliance systems, dosage benchmarks, manufacturing integration, and end-use products for professional B2B assessment.

    1. Pharmaceutical Intermediate for Antidepressant Synthesis

    In pharmaceutical production, 4-(4-Methoxyphenyl)-1-Butanol acts as a key building block for synthetic pathways towards selective serotonin reuptake inhibitor (SSRI) intermediates. Production chemists select it for its methoxy substitution pattern, supporting safe and effective stepwise construction of critical pharmaceutical scaffolds. Rigorous process controls guide its use in high-purity batch reactions, and compliance with GMP ensures traceability. Substitution efficiency and reaction kinetics determine its targeted inclusion, with QC confirming intermediate purity prior to downstream transformations that lead to active pharmaceutical ingredients.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF Monographs for intermediates (where available)
    • FDA 21 CFR Part 210/211: Current Good Manufacturing Practice for Finished Pharmaceuticals
    • European Pharmacopoeia General Methods (Ph.Eur.)

    Typical usage ratio

    • 0.8–1.2 equivalents relative to core heterocycle, adjusted based on side reaction suppression and molar yield optimization in multi-step synthesis.

    Downstream process integration

    • Early intermediate stage in multi-step organic synthesis of SSRIs and related CNS drug frameworks; introduced during nucleophilic substitution or reduction steps before coupling and protection group removal.

    Final product types

    • Pharmaceutical grade bulk intermediates for further API conversion
    • SSRI class antidepressants (e.g., citalopram derivatives)
    • Analytical reference standards for pharma QC labs
    • Research intermediates for preclinical CNS compound libraries

    2. Fragrance and Aroma Compound Manufacturing

    Manufacturers employ 4-(4-Methoxyphenyl)-1-Butanol in specialty fragrance synthesis for the fine chemicals sector. Its unique structure enables formulation of musk and floral nuances in aroma compositions. Process engineers control its introduction during aldehyde or esterification reactions, yielding high-stability volatiles suitable for luxury fragrances and technical aroma blends. Batch traceability follows IFRA safety guidelines to ensure compliance with end-market regulatory frameworks, with careful monitoring of olfactory thresholds and reactivity during scale-up.

    Industry compliance standards

    • IFRA Code of Practice (International Fragrance Association)
    • REACH Regulation (EC) No 1907/2006 for chemical safety
    • ISO 9235: Natural Aromatic Raw Materials - Vocabulary
    • COSMOS/Ecocert limits for use in natural perfume bases

    Typical usage ratio

    • 0.1–2% of total aroma concentrate; precise level determined by stability and nose panel assessment for target scent profile.

    Downstream process integration

    • Alcohol or ester synthesis stage; primarily combined with aldehydes for musk note development or incorporated in top/middle note carriers during compounding.

    Final product types

    • Luxury perfume base blends
    • Aroma components for personal care products
    • Air care chemicals for commercial scent systems
    • Fine fragrance modifications for home and personal use

    3. Fine Chemical Intermediate for Agrochemical Actives

    4-(4-Methoxyphenyl)-1-Butanol serves as an intermediate for certain herbicide and fungicide actives, enabling controlled functionalization during agrochemical synthesis. Agrochemical producers rely on its reactivity to introduce specific ether and alcohol groups, which enable targeted biological activity. Stringent adherence to product-specific environmental and toxicological regulations is mandatory at each stage, and in-process verification ensures batch-to-batch consistency for downstream field applications.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • OECD Principles of Good Laboratory Practice (GLP)
    • EU Regulation (EC) No 1107/2009 for plant protection products
    • ISO 9001 for documented process control

    Typical usage ratio

    • Variable, 5–15% of total synthetic batch for targeted chemical modifications—optimized according to final active structure and reaction efficiency metrics.

    Downstream process integration

    • Utilized post-core structure assembly for etherification or chain extension; directly enters pre-purification or crystallization prior to formulation of technical concentrate.

    Final product types

    • Precursor to selected herbicide molecules
    • Fungicide intermediates for broad-acre or specialty crops
    • Technical grade pesticide formulations
    • Agrochemical analytical standards

    4. Specialty Polymer Modifier Synthesis

    High-performance polymer manufacturers select 4-(4-Methoxyphenyl)-1-Butanol as a chain-transfer or end-capping agent in specialty resin formulations. Its specific functional groups contribute to modification of polymer physical properties, including flexibility, UV resistance, and controlled hydrophobicity. Raw material addition requires precise measurement, often during pre-polymerization, and compliance assurance focuses on trace impurities and polymer-grade purity aligned to customer contract specifications.

    Industry compliance standards

    • ISO 9001:2015 for documented quality management in polymer production
    • RoHS 2011/65/EU for restricted substances in electrical applications
    • REACH annexes for SVHC management in European markets
    • ASTM D256 for polymer impact resistance testing (where relevant)

    Typical usage ratio

    • 0.5–3 wt% as a chain-transfer or end-capper; dosage varies according to polymer backbone and required property modification (e.g., for custom acrylic resins, ratio set by target molecular weight and end-group content).

    Downstream process integration

    • Introduced during bulk monomer mixing stage before initiation of polymerization; also used in post-polymerization end-group functionalization for performance resins.

    Final product types

    • High-performance acrylic and polyurethane resins
    • Specialized adhesives for industrial bonding
    • UV-resistant coatings for electronics and automotive parts
    • Hydrophobic or chemically functionalized specialty polymers

    5. Photoinitiator Precursor for UV-Curable Coatings

    Manufacturers of photoinitiator components employ 4-(4-Methoxyphenyl)-1-Butanol as a synthetic feedstock for creating aromatic ether-based initiators in UV-curable varnish and ink production. It enters multistep syntheses where aryl–alkyl functionalities are necessary for compatibility with acrylate or epoxy systems. Process engineers closely monitor its conversion rates, ensuring consistent photoinitiator reactivity and low residuals for high-performance cured films. Regulatory conformity centers around occupational safety, emissions, and downstream product approval.

    Industry compliance standards

    • ISO 14001 for manufacturing environmental management
    • GHS (Globally Harmonized System) for safe handling and labeling
    • OECD Test Guidelines for Photoinitiator Toxicology
    • EN 71-3 for limits on toxic element migration in coatings (when used in toys and packaging)

    Typical usage ratio

    • 2–8 mol% in initial photoinitiator synthesis steps; adjusted by targeted absorption properties and cure speed of the UV coating application.

    Downstream process integration

    • Added during the stepwise arylation or etherification processes; follows through into the preparation of liquid or solid photoinitiator concentrates for final blending with acrylic or epoxy monomers.

    Final product types

    • Photoinitiator active blends for UV-cured varnishes
    • UV ink base compounds for high-speed printing
    • Clear and pigmented coating systems for optical or electronic substrates
    • Industrial adhesives cured by UV light
    Free Quote

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    Certification & Compliance
    More Introduction

    Introducing 4-(4-Methoxyphenyl)-1-Butanol: A Manufacturer’s Perspective

    What 4-(4-Methoxyphenyl)-1-Butanol Really Brings to the Table

    Each batch of 4-(4-Methoxyphenyl)-1-butanol tells a story about what careful chemical craftsmanship achieves. This compound, widely respected among specialty chemicals, stands out in more than simple purity numbers or technical jargon. Its structure, blending a methoxy-substituted phenyl ring with a butanol backbone, lets it offer both hydrophilic and hydrophobic interaction potential. That combination opens doors in synthesis that plain alkyl or aryl alcohols can’t manage. Most manufacturers and research teams who approach us for this product aren’t just searching for another building block — they're looking for a material that actually influences the pathways their chemistry can follow.

    In practical terms, this compound stands out for its robustness during multi-step synthesis. Reactions can run at slightly higher temperatures and in a variety of common solvents, saving time and minimizing pressure on glassware or containment. It’s always easier to work with a material that won’t throw a tantrum halfway through a scale-up. Knowing this helps our production planners feel confident during back-to-back drum-filling shifts — avoiding process upsets and making it possible to keep to timelines even during peak periods.

    Model, Batch Quality, and Our Real-World Specifications

    Working as a direct manufacturer rather than a repacker lets us control the process all the way from raw material selection to the final drumming. For our own 4-(4-methoxyphenyl)-1-butanol, we typically supply a technical and a research-grade product, each designed around the kind of work our clients actually perform. Research labs get material that crosses the 99% purity threshold on GC-FID, drawn from carefully monitored, smaller reactor runs. Bulk and industrial orders, often for fine chemical synthesis, pharmaceutical intermediates, or fragrance base production, receive a robust technical-grade material where tiny traces of noninterfering side products are acceptable provided functional performance remains intact.

    Purity is not just a marketing claim; it’s a quality-of-life issue for chemists running multi-step transformations. For most large-scale reactions, these specifications matter more than any neat phrase on a web page. Standard moisture content is held below 0.2%. We maintain strict controls over solvent and heavy metal residues, staying well under relevant pharmacopeia or REACH-guided requirements. In-house NMR, GC, and LC-MS records back up every batch we send out the door.

    Reflections from the Shop Floor

    Long hours spent on the factory floor or in the pilot plant yield insights no datasheet can ever show. The subtle smell from a finished batch reminds us of earlier days, running smaller glassware reactions, working to optimize every parameter. Watching a production run scale up — sometimes hundreds of liters in a stainless-steel tank — teaches more about temperature control, mixing speed, and efficient workup than any classroom.

    In every batch, small changes in raw material sources show up quickly. We’ve learned to lock in reliable upstream suppliers after only a single poor delivery. Reviewing a GC trace, you spot a sub-percent-level impurity and immediately know whether it comes from a raw aldehyde, a catalyst breakdown, or an inefficient workup. You take nothing for granted. Even the color of the intermediate or the appearance of a trace amount of precipitate at the bottom of a storage drum after a week hints at underlying stability. These little observations define how one batch of 4-(4-methoxyphenyl)-1-butanol differs from another, and ultimately, how well it will stand up in a customer’s hands.

    How Customers Actually Use 4-(4-Methoxyphenyl)-1-Butanol

    Most orders for this compound are headed for demanding applications. Pharmaceutical manufacturers often use it as a key intermediate, capitalizing on the molecule’s dual polarity. The butanol chain reacts smoothly while keeping the aromatic core intact, and the methoxy group adds electron-donating power that can direct subsequent substitutions with far greater selectivity. Chemists working in active pharmaceutical ingredient (API) pathways count on that kind of control; a stray side reaction costs time and money, and may mean weeks of backtracking.

    Fragrance and flavor houses also rely on this molecule's unique profile. The combination of aromatic and aliphatic characters adds both fresh and warm notes to blends. Unlike simpler butanol derivatives or linear aromatic alcohols, the methoxy group elevates olfactory complexity without the harshness that pure phenols sometimes bring. Sophisticated perfumers learn to appreciate the reliability and subtlety of this raw material, especially when every run matches the previous one.

    Polymer chemists can’t always swap in just any alcohol or ether. With this compound’s structure, they can introduce functionalized side chains into specialty resins or develop block copolymers featuring both flexibility and targeted hydrophilicity. Here, reaction reliability means less waste and better mechanical performance in the final product.

    Our Approach to Reliability and Transparency

    Years of manufacturing experience taught us that shortcutting material verification causes far more work than it saves. Each lot, whether destined for a research vial or a bulk shipment, passes through a repeatable series of checks. The first checkpoint is always within our reactor room, where in-line analytics verify the absence of runaway exotherms or off-target byproducts. Once cooled, a sample heads to quality control for GC, HPLC, and NMR checks. By handling everything ourselves, we’ve found problems early and headed off costly rework.

    Our on-site team also collaborates with key customers on custom batch sizes and packaging. If a research customer requests 25kg drums or pharma clients need specific handling safeguards, our filling station pivots accordingly — no detours through a trade house required. Logistical flexibility built in from day one makes real solutions possible.

    Comparing 4-(4-Methoxyphenyl)-1-Butanol to Other Products

    It’s easy to lump all aromatic butanols together, but close comparison reveals where 4-(4-methoxyphenyl)-1-butanol really stands apart. Starting with physical handling: the methoxy group on the para position affects melting point, solubility profile, and even aroma. Standard 4-phenyl-1-butanol lacks some of the nuanced synthetic options brought by the electron-rich aromatic system in 4-(4-methoxyphenyl)-1-butanol. The presence of the methoxy group also means slightly reduced volatility, which translates to safer handling and decreased evaporative loss, valuable characteristics in both small bench reactions and ton-scale storage.

    Looking at downstream chemistry, consider the example of Suzuki coupling or Grignard reactions. The methoxy group not only directs ortho substitutions through activation but also alters reactivity patterns in metal-catalyzed transformations. Pure alkyl or unfunctionalized phenyl butanols don’t allow this level of flexibility. In process development, this seemingly small change can unlock shorter, cleaner synthetic routes, which pay off in reduced solvent consumption, safer workups, and less purification hassle.

    Other suppliers may offer a crude product or one stripped of natural impurities using harsh methods, but our process avoids unnecessary stripping or masking agents, preserving stability. We skip complicated masking fluid additions and don’t rely on off-the-shelf stabilizers that interfere with later chemistry. Our customers appreciate knowing exactly what will show up in their flask, with nothing unknown to complicate synthesis steps.

    Meeting Regulatory Needs Without Cutting Corners

    Working in regulated industries challenges every manufacturer. Traces of unlikely contaminants, like nitrosamines, even in parts-per-billion, call for vigilance — especially for pharmaceutical, food, or cosmetic use. We monitor every batch against expected and novel impurities, drawing both on published research and direct customer feedback. Our regulatory team tracks changes in registration requirements from Europe to East Asia, updating our approach before new guidance becomes mandatory — not just waiting for a recall before taking action.

    Traceability also matters. Each package carries a batch code that links back to a complete record of raw material sources, personnel, and in-process adjustments. No small feat in times where global logistics sometimes sees months between order and fulfillment. Clear documentation at every stage, from raw material arrival to finished good delivery, lets all parties sleep better at night.

    Handling, Storage, and Everyday Lessons

    Even well-understood chemicals deserve everyday respect. On the floor, bulk storage of 4-(4-methoxyphenyl)-1-butanol benefits from standard stainless steel, but careful climate control preserves its fresh, neutral-to-slightly-anisic odor. We learned not to store drums near volatile acids or strong oxidizers. Over the years, we installed dedicated tankage and always allocate separate transfer lines to prevent cross-contamination — mistakes in bulk chemical handling echo in the final analysis reports.

    Spill response doesn’t require heroic measures, but every technician undergoes regular safety updates. Gloves, splash shields, and smart venting keep workplace exposure below the thresholds even state agencies demand. Pumps and lines get regular inspection; outfitting our equipment with simple flow meters catches leaks before drums empty out — experience taught that proactive maintenance beats reacting to late-night alarms.

    Listening to Partners, Improving Everyday

    Unlike a reseller or broker, we know the pressure that comes from a missed delivery. It’s personal when you’ve sweated in the reactor hall or managed a line at three in the morning to fix a clogged filter. Customers want predictable lead times, packaging that withstands rough transportation, and honest updates. We keep communication open about every delay, every process tweak, every improvement, because our reputation travels with each bottle and drum. Our best technical feedback doesn’t arrive through a website form — it comes late at night by phone or during plant visits, where visiting chemists share notes and tweaks they made to our material. We’ve seen a small packaging change, suggested by an overseas customer, result in less product loss during transit and fewer returns. Every improvement lands on our next production update.

    Over the decades, we’ve learned not to chase margin at the expense of reliability. Putting a quality product in the hands of partners building everything from new drugs to complex flavors takes daily attention on the shop floor, in the lab, and at shipping docks. We appreciate every customer who challenges us, who asks about the tiniest impurities or asks for custom documentation. Providing solid answers, based on lab reports and real-world practice, is a point of pride for everyone in our team.

    Why We Stand Behind Every Drum of 4-(4-Methoxyphenyl)-1-Butanol

    Every chemical, especially a nuanced one like 4-(4-methoxyphenyl)-1-butanol, reflects the cumulative choices, labor, and know-how gathered from years in manufacturing. The difference shows in long-term stability, consistent yields, and the trust labs place in our materials. We never treat any delivery as routine. If a process step or packaging design seems like it could work better, we test it ourselves before shipping out the change. No amount of process automation replaces attention to detail or the value of technicians who actually know the difference between a smooth batch and an off-color product.

    This commitment drives every improvement. Every time we prepare a batch, run spectroscopic checks, fill a drum, and ship it out, our team carries the responsibility and pride that come with being makers, not middlemen. Partners counting on our 4-(4-methoxyphenyl)-1-butanol get a product built for their toughest projects — consistent, robust, and always traceable to its source.

    Value Passed Directly On

    Direct manufacturing means every kilogram shipped starts with practical choices made by people who know what hands-on chemistry and industrial reality demand. When results count, so does the source. With 4-(4-methoxyphenyl)-1-butanol, we provide more than a chemical — we offer the quiet confidence born from years of listening, learning, and delivering what those at the lab bench and the plant actually need.