Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde

    • Product Name 4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde
    • Alias PC11
    • Einecs 629-022-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    719837

    Chemical Name 4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde
    Molecular Formula C14H10Cl2O2
    Molecular Weight 281.14 g/mol
    Cas Number 241861-08-3
    Appearance White to off-white solid
    Melting Point 84-88°C
    Solubility Slightly soluble in water, soluble in organic solvents
    Storage Conditions Store in a cool, dry place and keep container tightly closed
    Smiles Clc1ccc(cc1Cl)COc2ccc(cc2)C=O
    Inchi InChI=1S/C14H10Cl2O2/c15-12-3-1-11(10-13(12)16)9-18-14-5-7-17-8-6-14/h1,3,5-8,10H,9H2

    As an accredited 4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle with secure screw cap, labeled 4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde, 25 grams, includes hazard and handling instructions.
    Shipping The chemical 4-[(3,4-Dichlorobenzyl)oxy]benzaldehyde should be shipped in tightly sealed containers, protected from light and moisture. Package according to all relevant hazardous material regulations, including proper labeling and documentation. Ensure cushioning to prevent breakage during transit, and ship at ambient temperature unless otherwise specified by the manufacturer or SDS.
    Storage Store 4-[(3,4-Dichlorobenzyl)oxy]benzaldehyde in a tightly sealed container, away from light, moisture, and incompatible substances such as strong oxidizers. Keep the storage area cool, dry, and well-ventilated. Recommended storage temperature is room temperature (15–25°C). Clearly label the container, and ensure access is restricted to trained personnel. Avoid exposure to heat, flames, and direct sunlight.
    Application of 4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde

    Applications of 4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde in Industrial Manufacturing

    We supply high-purity 4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde for specialized industrial use. Our production supports downstream sectors focused on fine chemicals and key intermediates, where regulatory compliance, precise formulation, and consistent quality remain critical for manufacturers pursuing high-value, large-batch synthesis. Explore major sectors and application parameters below.

    1. Pharmaceutical Intermediate for Antifungal Drug Synthesis

    This compound serves as a core intermediate in the synthesis of triazole-class antifungal actives. API manufacturers value its reactivity for constructing benzyloxy-substituted aromatic scaffolds essential in various finished bulk drug substances. Strict manufacturing controls and traceability govern each batch used in regulated pharmaceutical settings.

    Industry compliance standards

    • cGMP (Current Good Manufacturing Practice, ICH Q7)
    • USP & EP API Intermediate Guidelines
    • FDA 21 CFR Part 210/211 for API production
    • ICH Q3A/B (Impurities in New Drug Substances/Products)

    Typical usage ratio

    • 0.6–1.2 molar equivalents per active pharmaceutical ingredient batch, adjusted depending on downstream conversion efficiency and required purity profile

    Downstream process integration

    • Added at benzylic etherification or aromatic aldehyde condensation stage during multi-step synthesis of triazole or imidazole antifungals such as posaconazole and related derivatives

    Final product types

    • Pharmaceutical bulk actives for oral and IV antifungal formulations
    • Registered intermediates for custom contract synthesis

    2. Agrochemical Intermediate for Fungicide Production

    Chemical manufacturers in crop protection employ this molecule as an intermediate for the synthesis of systemic and broad-spectrum fungicides. Unique substitution patterns deliver improved target binding and in-plant stability, making this compound integral to the development of patent-protected actives for cereal and specialty crop protection.

    Industry compliance standards

    • ISO 9001 for agrochemical manufacturing quality management
    • FAO/WHO Specifications for Pesticide Ingredients
    • EU REACH Registration for intermediates
    • China GB 2763 for pesticide residue limits

    Typical usage ratio

    • 5–15% by weight per intermediate reaction stage, varying by downstream target molecule and formulation pathway

    Downstream process integration

    • Utilized in etherification and aldehyde functionalization sequences for constructing benzyloxy-linked fungicidal agents, often upstream from Diels-Alder or cyclization steps

    Final product types

    • Industrial-grade fungicidal actives for formulating SC, WP, and EC crop protection products
    • Custom intermediates for new generation crop chemicals

    3. Fine Chemical Intermediate for Aromatic Ether Synthesis

    Our product is adopted in the production of high-value specialty aromatic ethers used in electronic chemicals, polymer additives, and liquid crystal material synthesis. Fine chemical producers rely on its dichlorinated, functionally-substituted structure to introduce tailored reactivity in advanced material applications requiring strict control over isomeric purity and contaminant profile.

    Industry compliance standards

    • ISO 9001 and ISO 14001 for quality and environmental management
    • RoHS (Restriction of Hazardous Substances) for electronic material use
    • REACH registration (EU Regulation EC 1907/2006)
    • Japanese METI requirements for chemical intermediates

    Typical usage ratio

    • 2–10% by weight in batch or continuous aromatic etherification; precise percentage depends on molecular end-use specification and downstream functionalization

    Downstream process integration

    • Introduced after initial aromatic substitution, serving as core substrate for coupling or further derivatization in liquid crystal and electronic-grade polymer assembly

    Final product types

    • Premium aromatic ethers for high-end LCD display manufacturing
    • Additives for engineering polymers and precision electronics

    4. Key Intermediate for Fragrance Ingredient Development

    Fragrance and aroma chemical manufacturers utilize this benzaldehyde derivative in the creation of functionalized aromatic building blocks for fine fragrances, fabric care, and home care scent formulations. The molecular profile allows the synthesis of highly stable, dichloro-functionalized aldehydes and ethers crucial for high-impact, long-lasting aroma compounds used in consumer brands worldwide.

    Industry compliance standards

    • IFRA (International Fragrance Association) Guidelines
    • EU REACH Ingredient Registration
    • US TSCA (Toxic Substances Control Act) for aroma chemicals
    • GMP ISO 22716 for cosmetic ingredient manufacturing

    Typical usage ratio

    • 0.1–1.5% by weight per fragrance ingredient batch, tailored to target aromatic impact, volatility, and downstream formulation requirements

    Downstream process integration

    • Added at aromatic condensation or etherification stages in aroma chemical synthesis sequences, forming higher molecular weight, stable aldehydic notes

    Final product types

    • Functionalized fragrance molecules for perfumery
    • Scented base materials for fine home and personal care products
    Free Quote

    Competitive 4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing 4-[(3,4-Dichlorobenzyl)Oxy]Benzaldehyde: A Manufacturer’s Perspective

    Directly From the Workshop Floor

    Watch the process of chemical manufacturing long enough and patterns reveal themselves. Some molecules earn their keep more reliably than others, working as foundation stones for advanced synthesis or specialty formulation work. 4-[(3,4-Dichlorobenzyl)oxy]benzaldehyde, known by many on our production teams as simply "the dichloro benzaldehyde," marks one of those dependable, high-value intermediates that generate interest with chemists across several industries. Having produced it in batches large and small, we’ve learned its distinctive quirks well — as much from experience as from technical literature.

    Identity and Structure

    Its molecular build features a dichlorinated benzyl group anchored to a benzaldehyde moiety through an ether oxygen. In practical plant terms, this combination delivers a building block with multiple reactive handles. We see its clear white to beige powder form roll off our lines, sent to formulators and R&D teams needing reliable intermediates that retain stability and manage reactivity in equal measure.

    What sets this compound apart is the 3,4-dichloro substitution. Chlorines in those positions on the benzyl ring lend distinctive performance advantages: higher resistance to metabolic breakdown and a real boost in downstream selectivity. Where unchlorinated or monochlorinated ethers sometimes fall short, this dichloro variant keeps its backbone locked in place during challenging reactions — a lesson our synthesis teams have experienced firsthand.

    Quality Built In, Batch After Batch

    Every drum and every bag that leaves our plant tells a story of consistent process control. We’ve built our purification workflow to weed out side-products and minimize trace contaminants — steps that some suppliers skip to cut costs, but we know what happens when downstream users face unpredictable impurities. Taking shortcuts on cleaning and drying introduces variables, and experience has taught us that their problems become ours in the end. Over time, our customers have come to value this attention to process detail. Chemists at pharmaceutical companies and specialty material producers want single-lot consistency in color and purity.

    Adaptability for Critical Applications

    4-[(3,4-Dichlorobenzyl)oxy]benzaldehyde has proven versatile across several sophisticated uses. In synthesis of pharmaceutical intermediates, researchers use its formyl group to fashion molecules with tightly controlled structural geometry. Its ether linkage and chlorinated arm limit undesired side-chain reactions or degradations. While chemists designing agrochemical actives and specialty dyes value this selectivity, the molecule also finds roles in fine-tuning lipophilicity and improving physical properties of target compounds.

    We’re often approached for custom orders — sometimes tighter purity specs, sometimes a demand for fine particle sizes or different solvents. By keeping core manufacturing steps under our direct control, we accommodate these requests more faithfully than outfits who rely on contract synthesis or third-party processing. Whether sending a few kilos for pilot trials or larger lots for full-scale commercial production, the method remains the same: reliable processing, routine checks, and built-in flexibility for those who need it.

    Looking Closer at the Chemistry

    Technical teams sometimes visit our facility, interested in walking through the actual process. Watching these professionals handle the material, they notice its stability during storage and resistance to moisture uptake. Stability in the warehouse means less loss between shipment and synthesis. In practice, that matters just as much as purity on paper. We’ve modified reactor conditions over years of trial: inlet gas flow rates, solvent choices, and temperatures. Tweaks in each variable shave hours off reaction times and boost overall yield, but only real-world experience guides which approach works best for this specific aromatic ether-aldehyde.

    Comparing With Other Benzaldehyde Derivatives

    Manufacturers like us regularly work with various benzaldehyde derivatives. Unsubstituted benzaldehyde, for instance, requires additional protection steps during downstream functionalizations — a headache our compound avoids. Simple 4-alkoxybenzaldehydes often lack the specific reactivity provided by the dichloro benzyl arm. Monochlorinated cousins fall short on chemical robustness, especially under harsher coupling or cyclization reactions. Some end-users pursuing new pharmaceuticals or advanced technical coatings report superior yields and fewer byproducts with our dichloro ether variant.

    Differences become apparent where precision matters: bench chemists see noticeably lower by-product profiles, and resin researchers report improved uniformity in cured product when using this molecule compared to single-chlorine or unchlorinated ethers. It comes down to fewer unwanted rearrangements and a more predictable reaction outcome. Customers bring us their process data directly, showing tighter product specifications on finished goods when starting with our compound.

    Real-World Case Histories

    Working side by side with our clients, we’ve supported dozens of process evaluations. One pharmaceutical development group highlighted time and again how their NMR scans tracked little to no extraneous peaks after using our standard-grade product. Another group, focused on specialty polymers, reported fewer purification steps in final product formulation. Unlike resellers and traders, we get firsthand feedback in real-time, letting us make small, measurable improvements batch to batch.

    During a project with a specialty coatings company, they struggled with incomplete cross-linking reactions using a lower grade, poorly purified compound from another source. Swapping to our 4-[(3,4-dichlorobenzyl)oxy]benzaldehyde, their process ran more smoothly without increase in waste. The finer details — dissolution rates, compatibility with other reactants, and particle size distribution — matter, and we keep these in focus during both process scale-up and daily production runs.

    Support for Advanced Synthesis Routes

    Some chemical intermediates look like simple trade items on paper, but the real-world picture is more subtle. Our plant technicians know that purification steps, solvent selection, and even packaging make a difference. For this compound, small missteps in drying or crystallization mark a real difference in downstream hydrogenations, reductions, or cross-coupling runs. We’ve invested in both closed-system handling and antistatic packaging, reducing risk of compaction, caking, or static buildup that plagues similar compounds from less careful producers. As a result, our customers report smooth powder flow and reduced downtime at their lines.

    Environmental and Safety Considerations Built Into Production

    Years of regulatory oversight and customer audits have forced us to adapt, often before it’s convenient. The dichlorinated nature of 4-[(3,4-dichlorobenzyl)oxy]benzaldehyde calls for careful waste management. Chlorinated byproducts need to be properly contained and processed, and our facility runs higher-grade abatement systems to catch vented organics and chlorine compounds. We favor closed-loop transfer for solvents and intermediates; it’s both a workplace safety measure and a cost savings practice. Operators see the benefits firsthand — reduced exposure incidents and improved air quality within the plant.

    Shipping teams know that moisture control and proper drum sealing reduce risks during transit. By investing in multi-layer packaging with built-in desiccant packs, we limit degradation or clumping after long shipments. Our chemical is labeled clearly, but we’ve moved away from some of the older packaging materials that proved less protective over time. Customers noticed less powder compaction, easier drum opening, and safer handling in receiving bays.

    Meeting Ongoing Regulatory Expectations

    Production standards must match or exceed global benchmarks. We’ve passed audits under several national and international frameworks, which means recordkeeping spans each step from raw material acquisition to labeling to final shipment. Documentation for every batch builds trust, especially for our pharmaceutical development partners. We maintain full traceability on incoming chlorinated aromatics and ensure our lot tracking system can answer traceability questions in a matter of minutes, not days.

    Beyond paperwork, the way we handle complaints or deviations matters. We’ve built a culture of prompt, open disclosure and corrective action, learning from each reported issue and folding those lessons back into operations. As newer environmental rules arrive, we prepare adjustments ahead of deadlines. Our experience running these lines means no sharp learning curves or missed compliance marks — only smoother production and better partnership with regulatory agencies.

    Technical Partnerships and Knowledge Sharing

    We regularly open our doors to visiting chemists and technical teams interested in production insights. Demonstrating our workflow on site, we emphasize open communication and hands-on learning. Over the years, our plant has hosted collaborative troubleshooting, test mixing, and even custom property tuning for specific industrial needs. By working directly with users, suggestions get incorporated quickly — from changes in particle size distribution to packaging improvements. Such feedback has helped us improve both the product and the way it’s delivered.

    Technical support doesn’t stop at the purchase order. Formulation specialists, R&D chemists, and industrial engineers contact us directly when process changes or new project requirements arise. Whether adjusting grades for medical synthesis or scaling up to pilot plant trials, the knowledge transfer is constant and responsive, drawing from our daily realities in the plant environment.

    Experience-Driven Process Improvements

    Improvements come from real engagement with both equipment and people. Plant technicians spot small drifts in color or smell before quality control tests flag them. We use internal feedback loops to log these observations, discuss probable causes on a regular schedule, and implement solutions that make a visible difference for the next batch. Whether adjusting the temperature profile in a reactor or changing the filter media after solvent exchange, changes are driven by direct observation and trial-backed evidence.

    Mistakes have their place: unplanned downtime during a condenser overhaul, or an unexpected side-product after a new cleaning protocol, have both prompted us to revise procedures. Rather than ignore such lessons, we embed them into process docs and training routines — applied knowledge in action, kept alive batch after batch.

    What Customers Value Most

    By talking to purchasing heads and technical managers, we’ve learned what truly matters isn’t just the listed specifications. They ask where the raw materials come from, how clean the process remains during scale-up, and what happens if a batch doesn’t meet agreed tolerances. In a market full of the same chemical name, subtle differences — in residual solvents, chloride levels, or flow properties — shift buying decisions decisively. We rely on routine, randomly sampled testing for residual metals and color, helping us catch quality drifts early. New customers soon report noticeably smoother processing on their end.

    Longstanding clients return for the reduced risk: fewer product recalls, less batch-to-batch variation, and a direct line to the people who produce and package each drum. Our open-door policy provides reassurance and clear lines of responsibility. When complications arise, our technical teams work shoulder-to-shoulder with customer personnel to troubleshoot and resolve issues on-site or remotely.

    Investments for Long-Term Reliability

    Scaling production rarely comes without a cost — in missed sleep, stressful troubleshooting, or major capital outlays. Expanding our capacity for 4-[(3,4-dichlorobenzyl)oxy]benzaldehyde took years of planning. Each new reactor, filter, or handling system required training and validation, but the payoff comes in predictable schedules and stable supply lines. We take pride in never leaving customers short, even as demand cycles shift or raw material prices fluctuate.

    Investments in worker training, automation upgrades, and waste management deliver returns not only in smooth production, but also in lower operational risk and fewer lost orders. Each improvement aims to knock out a point of potential failure, keeping output steady no matter the external pressures.

    Looking Forward: The Future of this Key Intermediate

    Markets rarely sit still, and neither do our product lines. Clients experiment with new application routes, and we respond by tweaking how the intermediate is produced, processed, or packed. As global interest in advanced pharmaceuticals and specialty polymers grows, demand rises for chemical intermediates that deliver predictable, high-purity performance into even the most regulated pipelines.

    Some customers now request structured documentation for food-contact or medical end uses, others push for low-carbon certifications or more transparent supply chain disclosures. Our long view means anticipating these needs before they shift from nice-to-have to must-have. Years on the floor have built a habit of proactive change rather than reaction, aiming always for both reliability and readiness for what comes next.

    Choosing a Trusted Intermediate Source

    We believe firsthand experience counts more than catalog specs or glossy product brochures. Each kilogram of 4-[(3,4-dichlorobenzyl)oxy]benzaldehyde delivered reflects not only our technical know-how but a firm commitment to service, safety, and ethical responsibility. Our clients — researchers, engineers, buyers — recognize the difference between commodity sourcing and a true partnership. By making our process transparent and ever-improving, we aim to support even the most demanding synthesis and manufacturing challenges for years to come.