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HS Code |
622011 |
| Name | 4-((2-nitrophenyl)amino)phenol |
| Common Name | HC Orange 1 |
| Cas Number | 54381-08-7 |
| Molecular Formula | C12H10N2O3 |
| Molecular Weight | 230.22 |
| Appearance | Orange to brown powder |
| Melting Point | 248-250°C |
| Solubility In Water | Slightly soluble |
| Boiling Point | Decomposes before boiling |
| Einecs Number | 259-407-0 |
| Application | Hair dye intermediate |
| Synonyms | 2-Nitro-4'-hydroxy-diphenylamine |
| Uv Vis Maximum | Approx. 400 nm |
As an accredited 4-((2-nitrophenyl) amino) phenol (HC Orange 1) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The packaging for 4-((2-nitrophenyl)amino)phenol (HC Orange 1), 25 grams, features an amber glass bottle with tamper-evident cap. |
| Shipping | **Shipping Description:** 4-((2-Nitrophenyl)amino)phenol (HC Orange 1) is shipped in tightly sealed, chemically resistant containers, protected from moisture, light, and incompatible substances. Handling requires compliance with transport regulations for hazardous materials, including appropriate labeling and safety documentation. Store and ship at ambient temperature unless specified otherwise by manufacturer guidelines. |
| Storage | Store 4-((2-nitrophenyl)amino)phenol (HC Orange 1) in a tightly sealed container, away from light, moisture, and incompatible materials such as strong oxidizers. Keep in a cool, dry, and well-ventilated area, preferably in a designated chemical storage cabinet. Ensure proper labeling and avoid exposure to heat or open flames. Use appropriate personal protective equipment when handling. |
Applications of 4-((2-nitrophenyl) amino) phenol (HC Orange 1) in Industrial Manufacturing4-((2-nitrophenyl) amino) phenol, commercially known as HC Orange 1, delivers industry-specific value as a high-purity dye intermediate in several targeted manufacturing sectors. As the original producer, we support global partners integrating this material into complex downstream systems demanding regulatory clarity, precision dosing, and controlled reaction conditions for quality-assured final products. 1. Oxidative Hair Dye FormulationLeading hair colorants manufacturers utilize our material as a direct dye component for oxidative and semi-permanent hair dye formulations. Its distinct chromophore structure is selected to produce vivid orange to amber shades in finished products. Our direct supply assures batch consistency and traceability, meeting international product safety demands. Industry compliance standards
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2. Acrylic Fiber and Polyamide Fiber DyeingTextile and synthetic fiber producers employ HC Orange 1 for dyeing polyacrylonitrile and certain polyamide (nylon) fibers, taking advantage of its strong affinity and uniform exhaustion properties. Selection criteria emphasize dye fastness, color reproducibility, and low residual content in effluent streams, meeting strict industrial and environmental expectations. Industry compliance standards
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3. Inkjet and Specialty Printing InksInk manufacturers incorporate our product as a key colorant in high-performance aqueous and solvent-based inkjet inks. Its molecular resonance ensures crisp orange hues and reliable printhead compatibility, particularly in textile printing, packaging, and coding & marking applications, addressing industry-driven demands for durability and brightness in end-use prints. Industry compliance standards
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4. Analytical Reagents and Histological DyesBiomedical and diagnostics laboratories procure pure HC Orange 1 as an ingredient for analytical reagent kits and as a component in histological staining protocols. Controlled manufacturing ensures minimal impurities, supporting high signal resolution in spectrophotometric and microscopy-based methods. Industry compliance standards
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5. Organic Synthesis Intermediate for AgrochemicalsAgrochemical manufacturers integrate HC Orange 1 as a coupling base or chromophoric intermediate in select herbicide and fungicide active ingredient syntheses. Its use supports defined structural modification and chromophoric marker synthesis under tightly controlled plant operating conditions, adhering to agrochemical regulatory and safety regimes. Industry compliance standards
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Working hands-on every week with 4-((2-nitrophenyl)amino)phenol—better recognized in the colorants world as HC Orange 1—lets us see the compound not just as a catalog item but as a practical tool. There’s nothing theoretical about what this orange dye achieves in real-world manufacturing. Each batch comes from solvents, stirrers, and reactors we operate, and we often field calls from customers with specific problems to solve. Bringing their feedback back into the plant, we keep refining what we deliver, not just in the molecule itself but in its utility, stability, and how it integrates into end-use systems.
As an aromatic amine-based phenol compound, HC Orange 1 offers characteristics that fit industrial colorant applications that demand more than simple tinting. We see it perform in oxidative and non-oxidative dye systems, especially in the personal care sector. Hair dye formulators rely on this molecule when looking for a particular vibrant orange shade that retains clarity and doesn’t dull after oxidation. The structure—a nitro group on the phenyl ring—contributes to distinct chromatic behavior, making it stand out compared to simple monoazo dyes.
In our work, this product often draws attention for its blendability and penetration, especially in hair color. It interacts well with a range of couplers and shows predictability batch after batch. This matters when formulators expect not only vividness but also minimal shift in tone under variable conditions. In formulations where discoloration or "muddying" of color presents a risk, HC Orange 1’s purity and performance under repeated stress tests proves its stability.
Talking about differences among sources, the challenge always comes back to consistency. We have invested in analytical controls on every lot—HPLC retention times and absorbance spectra—because no cosmetic or specialty chemical customer can afford surprises. By producing HC Orange 1 in our own reactors, monitoring every stage, we keep batch-to-batch color differences so tight that commercial users avoid the endless reformulation that often plagues buyers of off-spec or mixed-supply material.
For us, purity isn’t just about numbers. It means less interference from side-products in your downstream formulations. Even when small traces of precursor or isomer sneak past in products from less careful processors, the impact shows up as unpredictable changes in color saturation or fade resistance. We commit to high-purity standards—usually >99% by HPLC (excluding water content)—and not because it looks good on a certificate, but because any relaxation invites customer headaches.
Within the family of aromatic hair colorants, several compounds get compared to HC Orange 1. Aminophenols and nitrobenzene derivatives sit side by side in our lab. The real-world difference emerges in application: HC Orange 1 delivers both intensity and durability in oxidative conditions. Some monoazo or basic dyes may offer similar hue but lose strength in alkaline environments. Customers who tried shifting to purely azo-based colors reported problems with dulling, especially after repeat application and wash cycles. The oxidative stability baked into the structure of HC Orange 1 makes it a long-reaching solution for products subject to frequent washing and light exposure.
Beyond personal care, we often hear from developers in specialty paper and plastic colorants who ran performance trials with alternatives. They note that HC Orange 1 bonds with matrix materials more predictably. Unlike some other nitrophenyl derivatives, ours doesn’t easily migrate or bleed. These traits convince quality-driven manufacturers to stick with this product even at higher unit costs, because they see real net savings over time—less rejected product, fewer in-process adjustments, and more predictable color endpoints.
Each time we ship HC Orange 1, we know it’s headed into hands-on processes, not just laboratory beakers. Hair colorants remain the mainstay, reflecting the product’s original design, but we see growing interest in inkjet and industrial printing applications, along with some specialized textile printing. When working directly with cosmetic chemists, we hear persistent praise for the way our material disperses in semi-solid and high-viscosity bases. Even at high pigment loads, settling stays low and color intensity remains consistent.
Some customers use our technical consultations for formulation tweaks, such as balancing color drift over multiple application cycles or preventing unwanted interactions with metallic packaging. We’ve worked with end-product companies to resolve issues where batch contamination or impurities in other dyes led to color shifts. In several documented cases, switching to high-purity HC Orange 1 eliminated unacceptable drift over long storage periods.
Having supplied this dye into regulated markets for years, we stay tuned to rising scrutiny on aromatic amines and potential trace contaminants. As REACH and North American cosmetic regulations evolve, supply chains keep tightening. Our routines involve validated cleaning and verification cycles to keep every lot compliant, avoiding restricted byproducts and always running full documentation so customers can assure their own safety panels that the dye is up to code.
Testing for material safety, we have refined reclamation steps and continually monitored for mutagenic or sensitization liabilities. Our plant has adjusted conditions over the years—selecting harsher or milder solvents, adjusting reaction times—to deliver material falling reliably below identified thresholds for restricted substances such as aromatic nitrosamines. Our technical team actively participates in regulatory working groups to ensure up-to-date compliance and proactively respond to any new findings about intermediate stability or impurity risks.
Collaborative development covers more than just technical data transfers. Our personnel often join formulation trials with partners in their facilities, helping blend HC Orange 1 with both standard and novel couplers. The lessons from these joint efforts often feed directly into our production protocols. In one example, after repeated reports of inconsistent orange tones in an ammonia-based emulsion, our technical group spent several days on-site at the customer’s plant. They found that interactions with certain secondary amines in the base formula produced minor byproducts, resulting in slight color drift over shelf life. By adjusting our purification sequence and tightening storage protocols, we closed the loop, and the client saw the variance drop below detection.
We have set up remote and on-site troubleshooting for customers facing storage issues under high humidity or frequent thermal cycling. Our research chemists now include accelerated aging profiles in every batch validation. In regions where logistics take longer, such as tropical shipping routes or remote end-markets, we offer alternative packaging that markedly reduces both water uptake and particle aggregation.
In the last three years, demand for HC Orange 1 has shifted in tone and scale. We’ve seen a rise in requests for documentation of environmental fate, toxicity profiles, and renewable sourcing for precursor materials. Our work now frequently includes collaborating with downstream users aiming for eco-certifications or ingredient transparency labels. In response, we provide comprehensive traceability on solvent and precursor batches and have refined our own procurement to minimize exposure to non-sustainable feedstocks. By partnering with upstream raw material suppliers focused on green chemistry innovations, we can anticipate regulatory shifts and consumer demands for lower environmental impact.
Across regions, the story varies. European buyers are particularly sensitive to the nitro group’s reactivity and downstream environmental persistence, so we work proactively with waste management consultants to help customers dispose of or neutralize spent baths. In parts of Asia and South America, we’ve been asked for back-integrated support for claims related to workplace safety and exposure minimization, triggering us to invest in enhanced dust control and operator safety systems at our facilities.
Chemical manufacturing should not end at the plant gate. We field technical support for questions ranging from microscale solubility to full-scale mixing protocols. Users regularly share challenges around process upsets or unexpected shade variations. In return, we help diagnose potential causes, which may range from incompatible stabilizers to batch contamination with trace metal ions. For formulators blending HC Orange 1 with peroxide developers or antioxidants, we furnish actual real-process performance data, including rates of fading under standardized light and wash conditions, so they can predict performance with stone-cold confidence.
By keeping documentation and hands-on assistance strong, we foster a level of trust that carries through to the end consumer. After all, any batch failure or color imbalance on the retail shelf often gets traced back upstream. Our goal is to provide the kind of technical partnership that means fewer downstream surprises and a smoother path from pilot batch to mass-market product.
Efficiency and responsibility in production matter to our operation from both an environmental and a cost perspective. Over the past decade, we have moved away from heavier legacy solvents, implemented closed-loop nitrogen blanketing in storage and reaction vessels, and upgraded to energy-efficient reaction conditions. These changes didn’t come just in the name of compliance or public relations; they emerged from observing tangible process improvements—higher yields, better purity, reduced energy consumption, and less waste.
We continue to seek new process chemistries that will deliver HC Orange 1 of equal or better quality while lowering resource intensity. Solvent recovery has become a routine aspect: distillation and filtration systems now collect and recondition much of what once would have gone to waste. With local regulators monitoring discharge, we stay well within environmental permissions for every batch. The plant has also adopted in-process controls to capture energetic exotherms, avoiding instabilities that can sometimes arise in streamlining for scale.
Our commitment reaches into supply chain ethics as well. By choosing raw material suppliers with proven records of both worker safety and environmental stewardship, we try to ensure that every ton we ship stands up to scrutiny from customers, communities, and regulators alike. In an era where every component of consumer products faces examination, this approach builds both resilience and trust.
Evolution in chemical manufacturing is driven by those who use what we produce. Feedback from the field has shaped our methods over years of direct dialog with end users. We owe much of our innovation to customer insights—adjusting drying profiles to suit larger-scale mixing tanks, or tweaking particle size ranges so that mixing in viscous carriers never leads to grittiness or undispersed specks.
Our technical and customer support teams maintain an ongoing log of recurring issues and requests. In the last few product cycles, users have requested ever-tighter tolerances on particle size and moisture content, responding directly to subtle but critical impacts on drying schedules, formulation behavior, and shelf life. We responded by integrating additional steps in final drying and increased lot-wise particle size testing, contributing to smoother runs and less waste in downstream processes.
Increasing conversations now focus on lifecycle analysis. We are involved in collaborative projects to assess not only the cradle-to-gate impacts of HC Orange 1 but also its downstream life, including waste processing and consumer safety. Users share their own data from finished product testing, helping us deepen our knowledge of how the dye behaves under a wider range of conditions than any one lab can simulate in isolation. The flow of information proves essential: new risks surface, best practices coalesce, and incremental improvements take root.
Looking into the future, we see opportunities in markets looking beyond traditional cosmetic uses. Increasing requests come from advanced printing, plastics coloring, and functional coatings, each with unique technical hurdles. For high-performance plastics, resistance to heat and chemical leaching proves vital. Our R&D group continues to push formulations that resist color drift and maintain molecular integrity even under intense processing heat.
Digital printing companies have brought questions about ink formulation stability and dye migration. In response, we are developing enhanced versions and blends to reduce bleed and enhance print durability. In discussing requirements with clients rolling out new product lines, we have worked together, testing different dispersants and optimizing drying and fixation. Through such collaborative R&D, we move closer to market-ready solutions tailored for emerging needs.
Years of producing and troubleshooting HC Orange 1 have made clear that every step counts. Each stage of our process—from selecting raw materials, through refining reaction conditions, to targeted post-synthesis clean-up—directly shapes the outcome. By managing all of this in-house, we remain responsible for every lot that leaves our facility. We do not just deliver a dye; we deliver predictability, reliability, and a quality that users depend on for their own brand success.
We continue to push the envelope, testing new process methods, collaborating with customers on next-generation formulations, and improving our sustainability efforts. Through these efforts, we aim to keep 4-((2-nitrophenyl)amino)phenol a dependable cornerstone for color developers who see every nuance as a chance to build stronger products.