|
HS Code |
116205 |
| Cas Number | 2148-56-3 |
| Molecular Formula | C9H13N |
| Molecular Weight | 135.21 g/mol |
| Iupac Name | 3-phenylpropan-1-amine |
| Synonyms | Benzenepropanamine, 3-Phenyl-1-propanamine |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 242-245 °C |
| Density | 0.964 g/cm³ |
| Melting Point | -18 °C |
| Solubility In Water | Slightly soluble |
| Refractive Index | 1.528-1.531 |
| Flash Point | 98 °C |
| Smiles | C1=CC=CC=C1CCCN |
| Storage Conditions | Store in a cool, dry place, tightly closed |
As an accredited 3-Phenylpropylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 100 grams of 3-Phenylpropylamine, tightly sealed, labeled with hazard information, product name, and batch details. |
| Shipping | 3-Phenylpropylamine is shipped in tightly sealed containers, protected from light and moisture. It should be stored and transported at room temperature, away from sources of ignition and incompatible substances. The container must be clearly labeled, and the chemical must comply with all relevant regulations for safe handling and transportation of hazardous materials. |
| Storage | 3-Phenylpropylamine should be stored in a tightly sealed container, in a cool, dry, well-ventilated area away from sources of ignition. Keep it away from strong oxidizing agents, acids, and moisture. Store at room temperature and protect from light. Label the container clearly and ensure appropriate safety equipment, such as spill containment materials, is readily accessible in the storage area. |
Applications of 3-Phenylpropylamine in Industrial ManufacturingAs a direct manufacturer of 3-Phenylpropylamine, we focus on its validated industrial roles within established downstream chemical synthesis. This section outlines authentic application scenarios where this specialty amine functions as a key intermediate, phrased according to real manufacturing practice, compliance requirements, and integrated process flows. 1. Synthesis of Pharmaceutical Intermediates for Cardiovascular ActivesPharmaceutical companies integrate 3-Phenylpropylamine for constructing intermediates in active molecule synthesis, specifically antihypertensive and vasodilating drugs. The amine group enables efficient reductive amination or nucleophilic substitution, forming key building blocks in multi-stage synthesis. Quality control adheres to strict impurity profiles, and process validation ensures batch reproducibility during API precursor manufacturing. Industry compliance standards
Typical usage ratio
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2. Fragrance Ingredient Synthesis in Aroma ChemicalsManufacturers in the fragrance sector use 3-Phenylpropylamine to produce odorant bases, commonly through alkylation or acylation to form musky, floral, and phenolic compounds. The amine’s structure contributes to key notes in luxury and mass-market perfumes, and process control ensures traceability of precursors according to IFRA restrictions. Industry compliance standards
Typical usage ratio
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3. Agrochemical Intermediate in Selective Herbicide ProductionAgrochemical firms employ 3-Phenylpropylamine to construct amide or imine intermediates during selective herbicide synthesis. The primary amine reacts in controlled conditions to deliver functionalized ring systems with improved biodegradation profiles. Adherence to multinational standards for residual amine and impurity content is mandatory to support registration dossiers and environmental safety requirements. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Precursor for Cationic Surfactant Synthesis in Industrial CleanersChemical formulators utilize 3-Phenylpropylamine as a starting molecule to synthesize quaternary ammonium surfactants, vital for industrial and institutional cleaners. The amine undergoes quaternization or alkylation reactions, introducing cationic head groups that enable unique antimicrobial and surface-active properties. Batch traceability and formulation alignment with industrial and food contact regulations are crucial in downstream workflow. Industry compliance standards
Typical usage ratio
Downstream process integration
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Walking through the production lines, you learn to distinguish materials not just by their chemical names but by their quirks, their reactions, their strengths. 3-Phenylpropylamine is one of those chemicals you come to appreciate for its versatility and reliability. In our experience, its role extends beyond being just another specialty amine. Packing this product every day, we see demand coming from more than one direction: small labs, major pharmaceutical makers, fragrance houses, and even research startups finding new synthetic purposes for its stable, accessible structure. We produce it with a focus on clarity—clear liquid, stable purity, near neutral odor, holding up in storage and handling.
Chemists and process engineers often highlight 3-Phenylpropylamine’s C9 backbone, which sets it apart in aromatic amines. As manufacturers, we work with this structure in mind, paying close attention during distillation and purification to deliver a product that supports consistent downstream chemistry. You can tell when a batch is right by both analytical data and experience: colorless, low impurity, and free of residual solvents. Our typical material offers a purity of not less than 99% by GC, with only a trace level of water and minimal secondary amines. While these numbers might look like the everyday minimums, we know every decimal point holds meaning for those running scale-up reactions or regulatory submissions.
3-Phenylpropylamine isn’t just “produced”—it’s coaxed into its ideal form by a series of choices at every stage. Operators manage reactor temperature ramps carefully, since aniline derivatives can develop color and byproducts if things run too hot. We run repeated crystallizations and distillations, not just because a spec sheet demands it, but because subtle changes in product state can cause trouble for our downstream customers. Having direct control over each step lets us support not only current bulk orders, but also projects needing unusual grades or tight impurity profiles.
A fresher batch can make all the difference in certain hydrogenation or alkylation steps. Some of our clients want the product shipped out as soon as it clears QC, so we schedule extra pickups. In-house glassware and stainless reactors scale up from a few kilos to multi-ton batches, depending on market pulse. Each time a chemist or operations manager calls us to talk through how things actually go on the floor, it adds to our insight and lets us adapt—sometimes by tweaking purification techniques, sometimes by adjusting logistics for better shelf life.
Over the years, our 3-Phenylpropylamine has served applications across the map. In medicinal chemistry, it’s a recurring motif in intermediate libraries or target leads; you see requests spike ahead of certain regulatory cycles as teams look to secure material for filing. The chemical’s aromatic ring linked to a straight three-carbon amine chain offers both reactivity and selectivity, which process engineers put to work in several catalyst and ligand manufacturing schemes. In our lab, we’ve seen it pulled for aromatic substitution, reductive amination, and even specialty surfactant formulation.
Fragrance and flavor developers reach out for similar reasons—its structure fits well in notes meant to bridge natural and engineered scent profiles. Handling requirements in these industries focus less on chemical reactivity and more on minimizing off-odors and guaranteeing batch-to-batch sensory consistency. Recognizing that, we keep an extra tight rein on distillation conditions and prepack everything in low-permeability drums, catching requests before seasonal runs in the field begin.
Beyond established fields, we’ve seen an uptick in pilot-scale work leveraging 3-Phenylpropylamine in emerging areas: advanced polymers, surface treatments, and specialty coatings. These clients often seek multiple drum lots with rapid turnaround, and the only way to keep up is by holding steady on QA standards that allow us to sign off new customer profiles and guarantee ongoing reproducibility.
You hear questions about how 3-Phenylpropylamine stacks up against other similar amines. We’re hands-on with structures like benzylamine, phenethylamine, aniline, or meta- and para-substituted phenyl derivatives. The biggest difference lies in the side chain: with three carbons between the amino group and the phenyl ring, the molecule avoids some of the issues seen with shorter chains. Phenethylamine and benzylamine, for example, come with different boiling points and reactivity— our material is less volatile and less prone to decomposition under thermal load, which brings handling and storage benefits.
Operators report fewer emissions and easier temperature management in our reactors when working with 3-Phenylpropylamine, compared to its two-carbon cousin (phenethylamine). Physical handling improves as well—high purity means predictable melting/freezing behavior, less tendency to oxidize or darken, and consistent pH control without erratic acid-base balance. Chemists interested in substituent introduction or heterocycle formation often prefer this amine’s lower reactivity toward direct electrophilic attack on the core, which opens more reaction doors, especially in scale-up.
As manufacturers, we never discount the value of visibility. We carry out every stage—from sourcing and hydrogenation to purification and final QC—in our own facilities. Every batch reaches signoff only after a final round in our in-house analytical lab, which runs not only purity checks but also stress tests under simulated shipping conditions. Our chemists pay attention to trace component profiles, using NMR and GC-MS to document every lot and ensure customer records line up with regulatory expectations worldwide.
Product stewardship means staying in close contact with our key suppliers, maintaining full-chain audit trails, and tracking changing rules across markets. We keep safety data up to date, and provide transport documentation stating clear origin. For international clients, clear labeling, tamperproof containers, and full tracking remove much of the guesswork associated with bulk specialty chemicals.
Our direct involvement on the floor has taught us that no two lots are ever identical without intervention. Process variables—reactor workload, catalyst activity, raw material age—each play a part. We monitor these in real time, adjusting as batches run, because small inconsistencies in precursor purity or moisture can cascade unpredictably. Within our plant, early detection comes from regular inline sampling, and quick corrections mean less offgrade product heading to reprocessing.
Seasoned operators notice the little things—an unusual coloration in a distillate, a slight shift in odor profile, or a minor viscosity change. These don’t show up in standard endpoint testing, but they could signal trouble for an end user. Our intervention shuts off lots that “look right” on paper but don’t pass nose and eye checks familiar only to those who have filled, sealed, and shipped this compound for years.
The hands-on approach allows for rapid troubleshooting: filter upgrades, updated base washing steps, even custom glassware setups. These are tweaks we can implement by walking from the control room to the line, not by sending slow emails through a supply chain maze. Keeping these controls inside the factory lets us respond directly to urgency—whether triggered by a sudden spike in demand, a customer technical question, or a new formulation emerging from R&D.
Experienced chemical buyers know the headaches that come with documentation and compliance. Our compliance teams sit in the same buildings as our production managers, so questions about, say, REACH registration numbers or US import codes get resolved fast. We manage each regulatory filing and keep supporting records for at least a decade—far beyond the legal mandate—because old reference samples have solved more than one customer dispute. Each outgoing drum or container ships with batch analytics, stability data, and declaration of conformance, reflecting hands-on confirmation rather than theoretical extrapolation.
We regard adherence to global and regional standards as a core part of our role: customers receiving 3-Phenylpropylamine know that their storage and usage instructions reflect practical conditions, proven in our own facilities. From container selection to truck scheduling, we don’t cut corners—both for the safety of our workers and for your peace of mind.
The chemical industry has faced a renewed spotlight on sustainability. Direct production gives us room to optimize reactions for lower energy draw and less waste generation. For years, we’ve invested in closed-system reactions and vapor recovery—but the push toward green chemistry has us working on even longer solvent recycling loops. Operators track how much off-spec product and rinse waste leaves our gates monthly, and real efforts go into minimizing unnecessary drumming, repackaging, and short-dated batches.
Our commitment means using less hazardous feedstocks, choosing routes that avoid persistent byproducts, and redirecting spent process waters to in-plant treatment. Off-site, we search for routes to supply 3-Phenylpropylamine using greener precursors; our partners develop biobased benzene alternatives, which (though early) help us measure real long-term improvement against traditional petrochemical benchmarks. By controlling production from the front end, we guarantee our customers’ material comes with traceable sustainability records and meaningful carbon accounting.
Feedback from users on the ground has shaped our approach from the start. A request for a more controlled amine acidity, for instance, led to a tweak in our purification cascade that now delivers material with a narrower pH range upon shipping. A customer targeting high-throughput pharmaceutical screening asked us to minimize particulate generation; our response was to swap filter media and update our final drip points, ensuring a cleaner product with each run.
We keep close ties with formulators who bring back stories of product performance in the real world—chemical compatibility issues, unforeseen side reactions, longevity in storage, and ease of blending with exotic polymers. Each of these interactions sharpens our approach and leads to new QA checkpoints or subtle tweaks in our standard operating procedures.
Being a manufacturer, we’re responsible for the complete journey of 3-Phenylpropylamine from raw material to your plant door. Each production run feeds into a system of continuous improvement, shaped by years of practical experience and daily audits. Our customers expect each drum or flask to perform as the last; meeting that expectation comes from strict controls, not luck or supplier “trust.”
Product reliability is never taken for granted. Downstream projects in high-pressure research or regulated industries rely on upstream suppliers who can keep material steady through market swings, weather disruptions, or feedstock price crunches. Our approach means planned capacity buffers, robust inventory planning, and established redundancy across critical production stages.
Handling 3-Phenylpropylamine from synthesis to shipping underscores a simple truth—only the manufacturer can truly guarantee the character of what leaves the plant floor. Each batch, each container, holds thousands of small decisions and adjustments, each made with the end user’s needs in mind. The pride we take comes from a job done with care, an open line to every buyer, and the confidence that every drum reflects our direct input, our technical expertise, and our persistent drive for improvement.