Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

3-Phenoxytoluene

    • Product Name 3-Phenoxytoluene
    • Alias m-Cresyl phenyl ether
    • Einecs 209-234-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    440569

    Name 3-Phenoxytoluene
    Cas Number 4057-82-9
    Molecular Formula C13H12O
    Molecular Weight 184.23 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 288-290°C
    Density 1.05 g/cm³
    Refractive Index 1.578
    Flash Point 160°C
    Solubility In Water Insoluble
    Smiles Cc1cccc(c1)Oc2ccccc2
    Pubchem Cid 22004

    As an accredited 3-Phenoxytoluene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 100 grams, with secure screw cap; labeled "3-Phenoxytoluene," includes hazard warnings, lot number, and supplier information.
    Shipping 3-Phenoxytoluene should be shipped in tightly sealed containers, protected from physical damage and stored in a cool, well-ventilated area. Transport according to local, national, and international regulations for chemicals. Avoid exposure to heat, ignition sources, and incompatible substances. Properly label all packages and include a Safety Data Sheet (SDS) with the shipment.
    Storage 3-Phenoxytoluene should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. Protect the chemical from light and moisture. Ensure proper labeling and store at room temperature, avoiding excessive heat. Follow all relevant safety protocols and local regulations for handling organic chemicals.
    Application of 3-Phenoxytoluene

    Applications of 3-Phenoxytoluene in Industrial Manufacturing

    As a specialized manufacturer of 3-Phenoxytoluene, we serve industrial sectors utilizing this material as an intermediate in advanced organic synthesis. Our production quality supports integration into tightly regulated processes, providing consistent input for high-specification downstream products.

    1. Agrochemical Active Ingredient Synthesis

    Major agrochemical companies rely on 3-Phenoxytoluene as an intermediate in the production of selective herbicides and insecticides. Its high purity ensures controlled reactivity during etherification and further functionalization, directly impacting the yield and purity of active substances. Process chemists incorporate this material during the early-stage synthesis, often as a building block for phenoxy-substituted aromatic systems, enabling targeted molecular design. Consistent supply supports batch and continuous processing for crop protection agents intended for global export.

    Industry compliance standards

    • ISO 9001:2015 for quality management systems
    • REACH Registration (EU)
    • EPA 40 CFR Part 455 (USA—Pesticide Active Ingredient Manufacturing)
    • China National Standard GB 2763 for pesticide residue controls (as downstream requirement)

    Typical usage ratio

    • 10–20% by molar proportion in early-stage condensation and substitution reactions; adjusted higher for high-yield routes. Formulators select the ratio based on required phenoxy incorporation and downstream reactivity.

    Downstream process integration

    • Charged into batch reactors under controlled inert atmosphere.
    • Participates in Friedel–Crafts alkylation, etherification, and coupling reactions.
    • Undergoes further nitration or halogenation prior to active ingredient assembly.
    • QC monitored for trace impurities affecting biological activity of final APIs.

    Final product types

    • Phenoxy-substituted herbicides (e.g., MCPA-type products)
    • Pyrethroid-class insecticides
    • Intermediate key blocks for further agrochemical customization
    • Crop-specific customized pesticide formulations

    2. Pharmaceutical Intermediate Manufacturing

    Regulated pharmaceutical synthesis routes use 3-Phenoxytoluene as a modular precursor for generating aromatic scaffolds in certain active pharmaceutical ingredients (APIs). Medicinal chemists implement the material in processes demanding precise substitution, benefitting from our batch consistency and documented impurity profiles. The compound feeds into Grignard reactions, Suzuki couplings, and other transformations enabling the construction of bioactive compounds following strict GMP protocols.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • EU GMP Annex 8 for raw material control
    • USP-NF and Ph. Eur. monograph suitability for reference standards (as intermediate raw material)
    • 21 CFR Part 211 (cGMP for Finished Pharmaceuticals, USA, downstream requirements)

    Typical usage ratio

    • 5–15% of total organic phase by mol for multi-step API precursor synthesis; optimized in R&D based on route design, target molecule loading, and minimization of byproduct formation.

    Downstream process integration

    • Introduced in the initial aromatic synthesis stage.
    • Stored and handled in closed systems compliant with GMP material controls.
    • Acts as a coupling substrate for subsequent derivatization steps, including acylation, sulfonation, or further etherification.
    • QC programs track batch traceability and impurity carryover for regulatory filings.

    Final product types

    • Non-steroidal anti-inflammatory drug (NSAID) intermediates
    • CNS-active API intermediates
    • Custom small-molecule building blocks for CDMO supply chains
    • Advanced intermediates for patented pharmaceutical substances

    3. Liquid Crystal Monomer Development

    Display technology manufacturers select 3-Phenoxytoluene as a precursor for synthesizing liquid crystal monomers. Its aromatic ether bond enables desirable electronic and structural characteristics for nematic and smectic phase compounds. When processed using controlled chlorination or esterification, the material delivers essential features for liquid crystal alignment and stability. Production uses demand tight control of metal and halide impurities to reduce the risk of contamination in high-purity electronic applications.

    Industry compliance standards

    • ISO 14001:2015 for environmental management in chemical production
    • RoHS Directive (EU Restriction of Hazardous Substances) for electronics
    • IEC 61249-2-21 (halogen-free laminates and prepregs)
    • JIS C5012 (Japan, electronic material specifications)

    Typical usage ratio

    • 15–25% by weight in monomer synthesis batch; further dilution or concentration tailored during monomer polymerization according to end-use requirements in LC mixtures.

    Downstream process integration

    • Subjected to halogenation, esterification, or direct oligomerization in solvent-controlled environments.
    • Material charged after solvent dehydration and under moisture-free conditions to prevent degradation.
    • Processed in closed reaction vessels monitored for purity and process impurities (chlorides, peroxides, etc.).
    • Integration with polymerizable units for finalized LC monomer characteristics.

    Final product types

    • High-purity LC monomers for TFT-LCD panel production
    • Mixture components for advanced display technologies (OLED, AMOLED, e-paper)
    • Alignment layers and additives for liquid crystal alignment optimization
    • Intermediate resins for optical polymer films

    4. Functional Specialty Polymer Synthesis

    Producers of engineering plastics and specialty polymers include 3-Phenoxytoluene in custom formulations to impart specific solubility, thermal, and mechanical attributes. Current applications target poly(aryl ether) resins, where this compound acts as a monomer fragment supplying both flexibility and aromatic stability. Polymer chemists adjust addition levels during melt or solution polymerization, monitoring for chain length and transparency, which are key for high-performance plastic end uses. Our consistency in product appearance and low residual solvent aids in uninterrupted downstream compounding.

    Industry compliance standards

    • ISO 9001:2015 (quality management for specialty chemical production)
    • UL 94 (flammability rating for plastics, downstream requirement)
    • FDA 21 CFR 177.1595 (components of polyethersulfone resins, where applicable)
    • EU 10/2011 on plastic materials intended to contact foodstuffs (for food contact grades downstream)

    Typical usage ratio

    • 8–18% by weight as a comonomer or chain modifier; higher ranges increase polymer softness and solubility, while lower levels maintain rigidity and heat resistance in final molded plastics.

    Downstream process integration

    • Added directly to monomer mix prior to initiation of polycondensation or step-growth polymerization.
    • Incorporated in one-pot synthesis or sequential feeding during polymer chain extension.
    • Batches monitored for viscosity and molecular weight control to meet customer order specs.
    • Purified post-reaction to eliminate unreacted residues and color bodies.

    Final product types

    • Poly(aryl ether ketone) specialty resins
    • Co-polymer masterbatches for thermoplastic compounds
    • Optical grade transparent polymers
    • High-performance engineering plastics for automotive and electronics

    5. Industrial Fragrance and Aroma Compound Production

    Manufacturers of fragrance intermediates utilize 3-Phenoxytoluene for targeted etherification, yielding building blocks for phenolic aroma esters and musk-type perfumes. Flavour and fragrance chemists employ strict distillation and purification to achieve food-contact safe grades, where regulations permit, and maintain consistent batch organoleptics for large-scale functional fragrance manufacture. Control of trace contaminants is emphasized, given downstream safety and odor profile requirements.

    Industry compliance standards

    • IFRA Code of Practice for fragrance material manufacture
    • EU Regulation (EC) No 1223/2009 on cosmetic products (downstream compliance)
    • FCC (Food Chemicals Codex) for aroma substances (where food grade is produced downstream)
    • ISO 22716:2007 (cosmetics GMP, downstream application)

    Typical usage ratio

    • 3–10% by mass for each reaction batch in etherification or ester formation; formulation varies based on target base note intensity and compatibility with other fragrance ingredients.

    Downstream process integration

    • Added during early step in aroma compound synthesis with controlled heating and solvent choice.
    • Undergoes etherification or acetylation with high-purity catalysts.
    • Extensively purified via repeated distillation and fractional crystallization.
    • Batch-to-batch odour analysis to maintain sensory specification for each supply lot.

    Final product types

    • Musk and floral base notes for perfume concentrate houses
    • Phenolic aroma esters for shampoos, soaps, and air care
    • Fragrance intermediates for industrial and consumer blends
    • Customized aroma building blocks for fine fragrance creators
    Free Quote

    Competitive 3-Phenoxytoluene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    3-Phenoxytoluene: In-House Experience Behind a Proven Chemical Intermediate

    Manufacturing 3-Phenoxytoluene always feels like walking a path we know by heart, each step forged through years of refinement, feedback from long-term industry partners, and constant attention to purity. Unlike the larger catalogue molecules that crowd the fine chemicals market, 3-Phenoxytoluene stands out in practice for its manageable reactivity and predictable behavior through scaling. Its formula—where the methyl group clusters ortho to the oxygen-bearing phenoxy ring—might look simple, but this subtle adjustment delivers some welcome advantages for our downstream users.

    We produce this compound under the designation MPT-37. The process starts in our synthesis workshop using high-grade phenol and toluene derivatives, followed by a careful etherification step that our plant operators manage closely. The aim is clean conversion, minimal side-products, and an end product that can move straight into formulations like agricultural actives or pharmaceutical intermediates. The finished material reads in at a purity exceeding 99% by GC, and each batch brings its own documentation trail—from raw input tracking to batch QC data—because experience taught us the fastest way to lose trust is to let slip on transparency.

    Consistent Handling That Works on the Floor

    Industry customers tell us they most appreciate how 3-Phenoxytoluene doesn’t throw surprises during blending or secondary reactions. Its liquid form at ambient temperature means no one contends with dust or lumping, and the batch-to-batch consistency means operators don’t need to tweak parameters mid-campaign. In scale-up, the molecule keeps stable vapor pressures and manageable flash points, so teams handling drums or bulk tanks don’t get caught off guard.

    As a raw material, it has shown up in everything from herbicide scaffolds to dyes, always performing cleanly. Some of our larger partners in the agrochemical sector rely on MPT-37 for the backbone in selective herbicide synthesis, citing the sharp control it gives during halogenation or downstream sulfonation, without unwanted ring activation. They've tried alternatives from outside and came back to us citing fewer downstream purification headaches—costs drop when unexpected impurities don’t creep in, and the process equipment doesn't gum up.

    Defining the Essential Differences

    Chemical manufacturers quickly recognise where small differences in structure affect plant operations and product quality. 3-Phenoxytoluene behaves distinctly compared to its isomers—4-Phenoxytoluene in particular. That para-isomer may share the same atoms, but its reactivity, melting point, and even tendency toward oxidative discoloration can diverge. Operators in pigment production deal with inconsistent coloring if fed the wrong isomer, and it shows up in downstream shelf stability. Our customers specifically request the meta isomer because, over years of field use, they measured better shelf life in the finished paint systems and more reliable activity in regulated crop protection applications.

    Then there are comparisons with plain toluene or phenol ether derivatives where ring substitution isn’t selective. Synthetic chemists know these alternative materials tend to bring higher impurity levels after reaction with halogens or sulfonyl chlorides. Bulk chemical suppliers might ship generic materials at low price points, but our partners run cost analysis across the full campaign, including yield loss during purification and labor spent on rework. Long-term relationships with manufacturers have shown that the up-front investment into controlled 3-Phenoxytoluene production pays back in campaign success, less plant downtime, and fewer regulatory surprises at release.

    Day-to-Day Plant Reliability

    On the production line, plant teams don’t want to play detective with every new shipment. We have formalized every step, but it started with just listening to what the shop floor needed fixed last time. Unusual odor, drum sweating, or off-spec coloration usually meant something upstream wasn’t dialed in, so we went back to tweak filtration rates, adjust vacuum strength, or source higher purity toluene. Years of small corrections—sometimes as granular as polishing a vessel surface, or as major as updating line seals—have given us a process that rarely produces off-quality finishes. It feels routine now, but those basics create room for operators to focus on yield, not troubleshooting.

    Attention to handling characteristics goes beyond paperwork. If a shipment develops haze, we track backwards—often it’s a packaging seal issue, or a temperature fluctuation in the logistics chain. We respond in person, watching unloading and storage on customer sites, because recurring issues often come from small mishandling details. The lot-to-lot fingerprinting is tough to fabricate in spreadsheets, so plant managers gravitate toward suppliers who show up at the tank farm, ready to see any problems firsthand. Some customers have asked us to trial alternative drum liners; if it means tighter supply chain control, we do it. This ongoing dialogue with technical teams downstream is the reason we rarely see returns on our lots over the past several years.

    Feedback Loop with the Application Chemists

    Our R&D folks stay in contact with customer application chemists, not just on rare site visits but through a steady back-and-forth. Surface tension, solubility in mixed solvents, and reaction time—details we never assumed would matter so much—often turn up as a determining factor in the end-use setting. We map out where even minor shifts in impurity profiles or isomer distribution interrupt final product specs on their lines.

    Paint and polymer labs have described how trace impurity levels, invisible to most analytical screens, sometimes produce downstream color drift or unwanted cross-linking. 3-Phenoxytoluene—when produced with tight controls—brings the insurance that those “invisible” impurities stay out of the finished goods. We have reformulated our synthesis steps in response to site feedback, especially after one major coatings partner ran a campaign analyzing microcontaminants in ultraviolet-curable formulations. The trial batches that we made—with extra filtration and higher-purity solvents—produced nearly a ten percent drop in off-shade units. That sort of adjustment isn’t possible without open communication and genuine access to real-time performance data from the field.

    Cross-Sector Uses Show the Flexibility of MPT-37

    Some of the less-discussed virtues of 3-Phenoxytoluene come from the breadth of sectors that employ it. Producers in pharmaceutical fine chemical synthesis remark on its predictable stability through lengthy storage. In the flavor intermediate market, a few application chemists highlight its inertness and the fact that neutral aromatic profiles don’t interfere with taste panels. Agrochemical users rely on its selective reactivity and resistance to various oxidizing agents, which maintains activity where other aromatic ethers can fall short. The repeatability is the result of years spent managing variables like feedstock purity, reaction temperature, and post-synthesis polishing.

    We have seen it perform as a key intermediate in anti-microbial agent synthesis and in the construction of more sophisticated specialty chemicals. For instance, several partners working on next-generation dielectric fluids demand the meta isomer’s particular electronic profile. Over time, direct customer input and plant trial feedback cycles have given us a real-world education in just how much the "small" details make an outsize difference in final product performance and commercial practicality.

    Supply Chain Confidence Built In-House

    Trust builds across years and gets tested every time supply chains falter under pressure. Our team has managed to keep up baseline output during both planned plant turnarounds and sudden raw material shortages because we planned buffers not just on paper but on raw material contracts and in process flexibility. You won’t find us dependent on a single supplier for our core aromatics—our input contracts diversify risk, and our QC process screens every incoming batch before it ever reaches the synthesis train.

    One lesson from the past decade: documentation is only as good as the visibility the customer has. End users need COA detail and reference spectra, but what matters most is consistency in performance—from the first kilogram test batch to full container lots. Customers who started out spot buying now call in with strategic stockpiling orders, especially as regional disruptions or tariffs crop up. Our ability to deliver the same MPT-37 month in and month out, with full backward traceability, provides the kind of insurance that multinationals and independent producers alike consider non-negotiable.

    Regulatory and Sustainability Considerations

    Compliance doesn’t stop once we leave the plant gate. Downstream partners look well beyond just neutralization steps—they track lifecycle impacts and global movement of each container. We invested in updated MSDS, shipping, and import/export paperwork back before regulations ramped up, saving headaches as new disclosure and labeling rules came through. Our experience with restricted substances lists and compliance software means our 3-Phenoxytoluene always arrives ready for its next border, with all declarations in place. Plant investment in solvent recycling and emissions controls keeps audit results clear and customers confident.

    Sustainability goals grow more aggressive each year, especially for global brands. We spent years trimming waste streams—solvent recovery, water minimization, and process heat integration. Customers running environmental impact calculations for next-generation products appreciate being able to reference data on VOC content and waste minimization practices, not just material costs. The discipline required to keep emission rates low and waste streams manageable is something we treat as a competitive advantage; it also ensures compliance in all the jurisdictions we serve.

    Long-Term Value: Lessons from Multiple Campaigns

    We sit through customer “post-mortem” sessions each year, sometimes catching feedback not apparent in initial pilot runs. Someone will mention a downstream bottleneck, a filtration issue, or a spike in maintenance downtime. Every lesson folds back into production—whether in the way we rinse down reactors or adjust our inventory storage systems for better temperature control. A few years back, one batch’s trace impurity led to a full system-isolation protocol now built into every shift. Every iteration teaches something new about risk management and about the low-level details that maintain long-term partnerships.

    Repeat campaigns drive home the importance of stable handling and reliable purity. Some new users have tried substituting lower-grade material sourced from generics, only to return after accounting for the “hidden” costs—off-batch rework, lost yield, and missed delivery schedules. We have shared our cost-per-batch data with longtime partners, showing real savings over time. Lower initial purchase prices do not always add up when weighed against the time operators spend avoiding process upsets or when regulatory fines loom due to small amounts of “mystery” contamination.

    Improvement Never Pauses

    Manufacturing 3-Phenoxytoluene to our own standards pushes us to keep looking for process edges. Installing new in-line purification tech raised our baseline yield and made our effluent cleaner than before. Enhanced QC allowed identification and removal of a class of trace isomeric byproducts undetected by standard testing—a fix that reduced downstream customers' purification steps. We believe that each detail takes on new significance once large campaigns get rolling, because small fluctuations multiply quickly at scale.

    Our approach means never simply accepting “good enough” from the last campaign, but always seeking feedback from both process and application chemists, shipping supervisors, and maintenance techs. Stakeholders across each plant notice—delays decrease, equipment lifespan stretches, unplanned maintenance costs drop. Small improvements, year after year, accumulate into something you won’t see from outside firms who treat 3-Phenoxytoluene as just another line item.

    Reliability on the Ground, Confidence in the Future

    Demand for 3-Phenoxytoluene keeps steady across markets, and our commitment doesn't waver with shifts in supply outlook, regulatory pressure, or sector trends. We keep lines open to our partners, asking for honest feedback and sharing what works. Every time a partner calls us to ask for technical advice or logistical support, it confirms the value of working as a true manufacturer—not just another supplier pulling from an anonymous tank farm.

    We see the manufacturing of MPT-37 as more than a process or a product; it’s the outcome of collaboration, repeated learning, and the persistent drive to deliver reliability batch after batch. The difference between success and plant headaches often comes down to who makes your key intermediates and the care they bring to each shipment. If you want to see firsthand how the right details in chemical manufacturing add up, look to the history of 3-Phenoxytoluene: refinement, feedback, and a promise to keep improving—because plant operators, chemists, and end users deserve no less.