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3-Phenoxypropionic Acid

    • Product Name 3-Phenoxypropionic Acid
    • Alias 3-PPA
    • Einecs 242-424-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    178114

    Cas Number 2118-84-9
    Molecular Formula C9H10O3
    Molecular Weight 166.18 g/mol
    Iupac Name 3-phenoxypropanoic acid
    Appearance White to off-white solid
    Melting Point 47-49°C
    Boiling Point 305.5°C at 760 mmHg
    Density 1.183 g/cm3
    Solubility In Water Slightly soluble
    Flash Point 139.4°C
    Smiles C1=CC=C(C=C1)OCCC(=O)O
    Refractive Index 1.531

    As an accredited 3-Phenoxypropionic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 3-Phenoxypropionic Acid is packaged in a 100g amber glass bottle with a secure screw cap and clear, labeled markings.
    Shipping 3-Phenoxypropionic Acid is shipped in tightly sealed containers to prevent contamination and moisture exposure. Packaging complies with chemical safety regulations, often utilizing amber glass bottles or high-density polyethylene containers. All shipments are properly labeled with hazard information and accompanied by Safety Data Sheets (SDS) to ensure safe handling and regulatory compliance during transport.
    Storage 3-Phenoxypropionic acid should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizing agents. Protect the substance from direct sunlight and moisture. Store at room temperature and follow standard laboratory chemical hygiene protocols, including labeling and secure storage to prevent unauthorized access or spills.
    Application of 3-Phenoxypropionic Acid

    Applications of 3-Phenoxypropionic Acid in Industrial Manufacturing

    As a direct manufacturer specializing in fine chemical synthesis, we supply 3-Phenoxypropionic Acid that supports multiple established downstream industries. Our material consistently meets stringent quality standards for integration into advanced manufacturing lines. The following application scenarios reflect where our 3-Phenoxypropionic Acid delivers technical and regulatory value, with precise formulation roles, compliance requirements, and detailed process integration, leading to well-documented end products in global markets.

    1. Synthesis of Pyrethroid Insecticide Intermediates

    Our 3-Phenoxypropionic Acid serves as a key building block in the production of pyrethroid intermediates, widely used in agrochemical manufacturing to formulate leading insecticides for crop protection. Producers rely on its high-purity structure for controlled esterification with specific alcohols to form pyrethroid skeletons with targeted biological properties. The material enters the industry’s esterification and halogenation sequences, with its purity and residual profile directly impacting downstream product compliance and residue limits in global agricultural markets.

    Industry compliance standards

    • FAO/WHO JMPR pesticide specification guidelines
    • ISO 17034 for reference material production
    • REACH Annex XVII for substances in chemical plant protection
    • Chinese GB 2763 Maximum Residue Limits for Pesticides in Food

    Typical usage ratio

    • 0.95–1.05 molar equivalents per targeted pyrethroid intermediate, adjusting for reaction pathway and coupling yield

    Downstream process integration

    • Direct charging into esterification reactors with alcohol reactants and catalytic base for pyrethroid backbone assembly
    • Intermediate purification before halogenation, cyclopropanation, or further functionalization

    Final product types

    • Permethrin technical grade
    • Deltamethrin and cypermethrin intermediates
    • Formulated agricultural insecticide active ingredients (AIs)

    2. Pharmaceutical Synthesis of β-Blocker Precursors

    The fine chemical community has established 3-Phenoxypropionic Acid as an intermediate in the multi-step synthesis of certain β-blocker APIs (active pharmaceutical ingredients). Pharmaceutical manufacturers employ strict process control of impurity profiles, sourcing this acid for peptide bond formation or as a synthon for chiral resolution in candidate molecules that underlie cardiovascular therapeutics. Controlled addition correlates with downstream yield and safety data in validated plant-scale processes.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • FDA 21 CFR Parts 210/211 (cGMP)
    • European Pharmacopoeia Monographs (for relevant intermediates)
    • ChP (Chinese Pharmacopoeia) for registered intermediates

    Typical usage ratio

    • 0.8–1.2 equivalents in amide coupling steps, adjusted for stoichiometry and loss on work-up

    Downstream process integration

    • Amide bond formation for active side-chain assembly under controlled anhydrous conditions
    • Purification prior to hydrogenation or chiral separation to secure β-blocker selectivity

    Final product types

    • Intermediate compounds for atenolol and metoprolol synthesis
    • Finished β-blocker API bulk powder
    • Registered pharmaceutical intermediates for CDMO supply chains

    3. Liquid Crystal Monomer Production for Display Technology

    Manufacturers in specialty electronics use 3-Phenoxypropionic Acid as a starting raw material in the synthesis of tailored aromatic esters for liquid crystal monomer formulations. These monomers incorporate specific chain lengths and ring structures crucial to display performance parameters, such as switching speed and optical clarity. The acid enters highly controlled condensation reactions, typically subject to electronic and purity specifications detailed by display panel OEMs.

    Industry compliance standards

    • IEC 62321 for hazardous substance analysis in electronic products
    • RoHS (EU Directive 2011/65/EU) for restriction of hazardous substances
    • Customer-specific QMS and approved supplier list (ASL) requirements
    • ISO 9001:2015 certified production processes

    Typical usage ratio

    • 0.95–1.10 molar ratio relative to diol/phenol core compounds, controlled by desired liquid crystal birefringence

    Downstream process integration

    • Feeding into acid chloride formation, followed by etherification or esterification in high-purity reactors
    • Filtration and fractionation prior to monomer polymerization for LC panel applications

    Final product types

    • Liquid crystal monomer feedstocks
    • Finished LC materials for TFT and IPS display modules

    4. UV-Curable Resin Formulations for Coatings Industry

    In the advanced coatings sector, 3-Phenoxypropionic Acid is valued as a monomeric component in UV-curable acrylic and urethane resins, especially where high thermal stability and scratch resistance are required. Coating formulators precisely meter the acid for copolymerization, optimizing viscosity and adhesion parameters on automated production lines for high-performance flooring, optical, and electronic component coatings.

    Industry compliance standards

    • EU REACH substance registration (No. 1907/2006/EC)
    • ASTM D7767 for UV/EB cure coatings composition
    • ISO 16000 Indoor Air Quality for low-VOC resin systems
    • GB 18582 Chinese indoor paint and coating standards

    Typical usage ratio

    • 2–6% w/w of total resin solids, optimized for desired hardness and curing profile; side chain compatibility may require tuning within this range

    Downstream process integration

    • Inline mixing with acrylic or polyurethane prepolymer bases, followed by photoinitiator incorporation
    • Continuous film casting and UV irradiation for polymer network formation

    Final product types

    • Clear and pigmented UV-curable industrial coatings
    • Protective varnishes for electronics and optical substrates
    • High-durability flooring and automotive topcoats
    Free Quote

    Competitive 3-Phenoxypropionic Acid prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    3-Phenoxypropionic Acid: A Closer Look from the Manufacturer’s Perspective

    Introducing 3-Phenoxypropionic Acid in Daily Production

    We manufacture 3-Phenoxypropionic Acid to meet demands from some of the most critical industries in the chemical landscape. Having worked with this compound for years allows our team to keep up with the changing standards, real-world processing challenges, and the needs of formulators who build their products upon specialty chemicals like this one. The chemical structure of 3-Phenoxypropionic Acid, C9H10O3, shows off a unique blend of phenoxy and carboxylic acid groups—traits that influence its roles across a spectrum of end uses. Our batches come consistently in high purity, and our quality checks focus on trace impurities and packing stability, which always end up affecting downstream yields and finished applications more than spec sheets can show.

    Specifications Built Around Real Usage

    Across requests, nearly every client wants to know more about the technical profile of 3-Phenoxypropionic Acid. We typically offer material as off-white crystals, with purity routinely above 99%. Moisture control matters throughout the process, so we keep water content under 0.5%—drying systems are tuned to guarantee this. Melting point generally falls between 46°C to 48°C, a range that enables handling in typical ambient storage and processing setups. Residual solvents, namely toluene or DMF, sit well below common acceptance criteria due to thorough solvent recovery at our facilities. Additionally, the content of related substances—especially isomeric byproducts and unreacted precursors—remains closely monitored, usually below 0.3%, since any higher levels end up giving off-character signals in most use-case chromatography tests.

    With strict batch-to-batch tracking, our lot records include pH of aqueous solutions, ash values, and appearance notes gathered straight from production chemists. These details stem not from a bureaucratic exercise, but from experience—knowing that small surprises in raw material can occasionally bring larger headaches for formulators later on.

    How We See Quality: Lessons From the Ground Floor

    Building 3-Phenoxypropionic Acid from raw starting materials involves repetitive crystallization, acid-base neutralizations, and extensive purification steps. Routine analysis of each process stage means fewer surprises during packing and shipping. There isn’t much luxury for error—the end markets expect predictable performance. Sometimes, a single missed color change or tiny shift on the IR spectrum forecasts hours lost in reprocessing. Feedback directly from users over the years—especially those manufacturing agrochemical intermediates or specialty esters—keep shaping how we monitor and tighten key parameters. Unreacted starting material, trace solvents, and slight organoleptic differences crop up much more often than industry surveys tend to admit. People, not just testing instruments, double-check every order for abnormalities that only repeated hands-on experience picks up.

    Our production team values consistency. Without it, coatings and specialty intermediates struggle to deliver their mechanical or chemical resistance. Purity alone doesn’t always tell the full story; off-ratio side products and even subtle chiral impurities can throw off reaction chains in ways that software predictions never quite catch.

    The Realities of Usage: More Than Just a Name

    Clients ask about our 3-Phenoxypropionic Acid for reasons that go far beyond commodity interest. In our largest segments, this compound supports synthesis of ester-linked fungicides, herbicides, and insecticide intermediates. As a manufacturer, it becomes obvious that even a half-percent fluctuation in input material can halve a plant’s profit, especially in continuous or semi-continuous esterification lines. Direct feedback from downstream users who run their plants at full load reveals patterns: high-purity acid translates to longer catalyst life, fewer cleanouts, and reduced batch failures.

    Pharmaceutical intermediate producers cite 3-Phenoxypropionic Acid as part of multi-step reaction schemes. Quality there means more than yield; process validation and consistent impurity profiles are vital, especially for scale-up from lab pilot to full production. Research teams focusing on developing new aromatic carboxylic acid derivatives for active pharmaceutical ingredients demand extremely tight control of known and unknown impurities. Our experience suggests that standard purity thresholds don’t always catch the outlier cases. Regular dialogue with industry labs taught us to invest in high-sensitivity detection methods—both to identify invisible threats and to make sure regulatory submissions run smoothly after drug master file preparation.

    We work with custom blend operations as well—customers who use 3-Phenoxypropionic Acid as a backbone for advanced coatings, specialty resins, and surface treatment agents. Here, the most valued trait isn’t always chemical reactivity. It’s about absence of coloring, low transition temperatures, and the total removal of metallic ions that can poison catalyst beds. Years ago, one paint formulation team flagged trace iron that originated from an upstream valve; fixing the root case and retesting our protocols taught us how easily a sub-ppm contaminant can change a batch color beyond agreed tolerances.

    Comparing 3-Phenoxypropionic Acid to Related Compounds

    3-Phenoxypropionic Acid often gets compared with analogs like 4-Phenoxybutyric Acid or the structurally similar 2-Phenoxypropionic Acid. Many users ask about substitutions, new synthesis routes, or whether an alternative molecule can lower cost or raise yield. Our shop has tested these routes both in pilot-scale and production—3-Phenoxypropionic Acid stands out due to its intermediary reactivity, steric profile, and ability to selectively form esters and amides without excessive byproducts.

    3-Phenoxypropionic Acid provides a phenoxy group directly linked to a propionic acid side chain, which gives it special characteristics not shared by longer-chained or differently substituted acids. 2-Phenoxypropionic Acid, for example, places the carboxyl closer to the aromatic ring, affecting both reactivity and resulting physical parameters—most notably in esterification speed and intermediate solubility. Users notice real-world differences in volatility, processing losses, and reaction selectivity especially as they move to multi-ton scales.

    While both compounds can act as precursors, 3-Phenoxypropionic Acid usually ends up favored for making certain pesticidal esters due to its specific side-chain positioning and ease of downstream purification. Side reactions turn out fewer byproducts than with the 2- analog thanks to reduced ring activation. The propionic skeleton also brings more balanced hydrophobic and hydrophilic properties, making it easier to formulate stable emulsions or suspensions in water-based systems. These subtle factors matter a great deal, particularly in industrial production, where even minor changes in solubility or reactivity can disrupt line speeds or require extra cleanup steps.

    Commitment to Quality—Why Hands-On Experience Matters

    It’s easy to describe 3-Phenoxypropionic Acid with technical numbers or spec tables, but drawing from our years at the reactor and filtration line tells a deeper story. Each batch shows unique behaviors—sometimes a slightly different crystal habit, a material flow property, or a drying time that shifts as seasons change. Summer humidity, winter cold snaps, and even the load on municipal steam impact how product leaves our facility. Holding purity above 99% isn’t a game of checklists—it comes from a constant loop of running pilot batches, dissecting failures, and listening both to the lab data and the production crew’s observations.

    A solid technical team watches for the outliers. Our operators learned that batches dried too quickly sometimes carry a static charge, caking inside drums or making handling tricky at the customer site. Our warehouse crew spotted product discoloration linked to one particular drum liner material; after a short investigation, we swapped it out, getting closer to the neutral, clean crystals that customers expect. Shipping finished chemical is more than just tanks and trucks; it means ensuring the right label, the real purity, and the package integrity, all matched to minimize risk in a real-world supply chain.

    Our company maintains strict records not to impress onlookers but because recovery from a single customer claim costs time, money, and professional relationships. As more downstream users move to green chemistry and cut their solvent loads, the demand for ultra-clean, low-residue 3-Phenoxypropionic Acid grows further. Partnerships with trusted transporters means product arrives in the same condition as it left our floor. Experience across thousands of tons shipped each year lets us navigate customs or regulatory hurdles without keeping buyers waiting.

    Responding to Regulations and Market Trends

    The regulatory world for chemicals like 3-Phenoxypropionic Acid tightens every year, whether that’s due to REACH requirements, local environmental guidelines, or growing pressure to document life-cycle impacts. We respond proactively—changing how we source phenol, improving effluent treatment, and regularly testing batches for persistent organic pollutants or banned byproducts.

    As concerns mount about plant safety and environmental health, especially around phenol derivatives, more users dig into trace metal content and impurity carryover. We’ve equipped our labs with better GC-MS and HPLC tools to catch emerging targets, not just those flagged by the customer. Our technical team works closely with buyers to provide in-depth batch histories, not simply certificates of analysis. These open files help downstream users with their own audits, and improve the entire chain’s ability to track quality from source to application.

    Recycling takes on new urgency in recent years, so our process optimization tracks effluent, distillation residues, and energy use meter by meter. Routine updates ensure that our finished product holds up not just against today’s standards, but whatever rules a region might introduce in the coming years. Lab teams report quarterly on process emissions, and operators on shifts propose tweaks—often small but impactful—to reduce waste without impacting yield or schedule.

    Challenges and Solutions Learned Over Time

    Plant chemists and operators have seen just about every type of hitch, from pumps losing prime during a batch run to unexpected residues after aging in storage. Sometimes, the reality of chemical production runs counter to textbook explanations. Batch failures might tie to a single faulty gasket, or to lab glassware rinsed less thoroughly than assumed. Our team learned to run parallel checks, not rely solely on automated sensors, and to talk through each anomaly. When customers report unexpected results in a downstream formulation, our first calls go to those who know the product handling firsthand.

    Improvements seldom come from sweeping changes. Instead, incremental gains—tweaking the recrystallization solvent, extending drying phases, adopting more robust internal batch trace numbers—drive longer-term stability. Feedback loops include not only customer returns but voluntary reports on how 3-Phenoxypropionic Acid performed in benchmark reactions, during pilot runs, or under stress tests like aging in high humidity. Our adjustment process often uncovers subtle issues: variation in barrel liner thickness, minor shifts in pH of rinsing water, or changes in local tap water mineral content. Since real-world chemical manufacturing involves so many moving parts, only consistent documentation and honest post-mortems deliver meaningful, sustainable fixes.

    Trends Shaping the Future of 3-Phenoxypropionic Acid

    Demand has shifted with the global move toward greener formulations and tighter hazard classification. Clients need 3-Phenoxypropionic Acid that holds up under reduced solvent conditions, works with alternative catalysts, and carries a proven track record for both synthetic efficiency and environmental stewardship. The drive for biodegradable, lower-toxicity final products places even greater scrutiny on source materials. To match this, we push for more selective synthesis, continuing to adapt our processes and broadening the analytical techniques we employ to guarantee fewer trace unknowns.

    In the past, much of the market for 3-Phenoxypropionic Acid linked to cost per ton and ease of shipment. That has shifted, as both regulatory hurdles and end-user requirements place more value on transparency, traceability, and technical support. Industrial R&D teams increasingly want origin stories for their raw materials, pathways for waste minimization, and guarantees on absence of certain classes of impurities—some legislated, some driven by private certification.

    As additive manufacturing, custom coatings, and new classes of crop protectants roll out, 3-Phenoxypropionic Acid moves from a background player to a visible, regulated, and specified intermediate. This trend pushes us to track each production stage, engage directly with formulation researchers who try new synthesis routes, and test for emerging contaminants or regulatory targets even before they hit widespread notice.

    The Human Element—What Keeps the Work Honest

    Manufacturing specialty chemicals like 3-Phenoxypropionic Acid means relying as much on experience as on equipment. Every year brings up new questions from curious buyers: “Is this batch safe with a new catalyst?”, “Why did our test batch show slight color variance?” or “Can you guarantee every drum carries less than 1 ppm of a certain byproduct?” Only a history of real troubleshooting, open dialogue, and the willingness to adjust production schedules matches demand for flexibility and quality.

    Our facility’s record shows dozens of cases where fixing a single minor defect—be it tweaking reaction pH, changing drying airflow, or trialing a new inert liner—led to higher yield, faster batch turnaround, or greater customer satisfaction. This comes not from luck but from constant iteration, investment in skilled hands, and respect for the feedback loop running all the way from the reactor to the end user.

    Trust builds through transparency. End users do not just buy chemical—they buy the history, the method, the vigilance behind every batch. 3-Phenoxypropionic Acid might look simple on a datasheet, but day-to-day experience tells a deeper story. Each production run gives the chance to learn, refine, and deliver material that does its job—without surprises, setbacks, or the kinds of invisible flaws that derail whole projects.

    For us, it’s about more than molecules. It’s about learning from every outcome—planned or surprise—so every drum of 3-Phenoxypropionic Acid reflects not just chemical precision, but the working knowledge and integrity of those who made it.