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3-Phenoxy-Benzaldehyde

    • Product Name 3-Phenoxy-Benzaldehyde
    • Alias 3-Phenoxybenzaldehyde
    • Einecs 246-422-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    719860

    Chemical Name 3-Phenoxybenzaldehyde
    Cas Number 39515-51-6
    Molecular Formula C13H10O2
    Molecular Weight 198.22 g/mol
    Appearance White to light yellow crystalline solid
    Melting Point 47-49°C
    Boiling Point 273°C
    Density 1.19 g/cm³
    Solubility In Water Insoluble
    Smiles C1=CC(=CC=C1C=O)OC2=CC=CC=C2
    Inchi InChI=1S/C13H10O2/c14-10-11-5-3-6-12(9-11)15-13-7-1-2-8-13/h1-10H
    Refractive Index 1.623
    Storage Conditions Store in cool, dry place, tightly closed
    Flash Point 139°C
    Synonyms m-Phenoxybenzaldehyde

    As an accredited 3-Phenoxy-Benzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 3-Phenoxy-Benzaldehyde is packaged in a 100g amber glass bottle with a secure screw cap and hazard labeling for safety.
    Shipping **3-Phenoxy-Benzaldehyde** is shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. Transportation complies with relevant chemical regulations, including labeling and documentation. The product is typically sent by ground or air, based on destination and quantity, ensuring safe transit under controlled temperature and storage conditions to prevent decomposition or spillage.
    Storage 3-Phenoxy-Benzaldehyde should be stored in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizers and acids. Keep the container tightly closed and protected from light and moisture. Ensure proper labeling and use secondary containment to prevent accidental spills. Store at room temperature and avoid prolonged exposure to air.
    Application of 3-Phenoxy-Benzaldehyde

    Applications of 3-Phenoxy-Benzaldehyde in Industrial Manufacturing

    3-Phenoxy-Benzaldehyde plays a crucial role in several distinct chemical manufacturing sectors. As an upstream aroma intermediate and synthetic building block, this raw material supports high-value formulations in the regulated agrochemical, pharmaceutical, and aroma chemical industries. This section outlines real-world application scenarios in which manufacturers have integrated the material into dedicated downstream production processes, addressing formulation specifics, compliance thresholds, and manufacturing control points.

    1. Pyrethroid Agrochemical Synthesis

    3-Phenoxy-Benzaldehyde serves as a core intermediate in the industrial synthesis of pyrethroid insecticides, including permethrin, cypermethrin, and lambda-cyhalothrin. Manufacturers utilize this aldehyde for its crucial phenoxybenzyl moiety, directly impacting the selectivity and potency of resulting actives. The raw material enters the manufacturing workflow as the precursor in the condensation reaction with cyanohydrin intermediates, forming the phenoxybenzyl alcohol structural backbone that defines the efficacy of these crop protection agents. Production lines must comply with strict residual impurity limits set for agrochemicals to ensure downstream batch release compliance and environmental safety.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products (FAO/WHO, e.g. Permethrin TC)
    • EU Regulation (EC) No 1107/2009 concerning the placing of plant protection products on the market
    • US EPA Pesticide Registration Requirements (40 CFR Part 158)
    • REACH Regulation (EC) No 1907/2006 for chemical intermediates

    Typical usage ratio

    • 0.95 – 1.05 molar equivalent relative to cyanohydrin intermediate, adjusted per process yield and purity requirements

    Downstream process integration

    • Condensation reaction with malononitrile or similar cyanohydrin in batch or continuous reactors, followed by reduction and esterification to form active pyrethroid esters

    Final product types

    • Technical-grade pyrethroids (e.g. permethrin TC, cypermethrin TC, lambda-cyhalothrin TC)
    • Formulated insecticides: EC, SC, CS crop protection products

    2. Pharmaceutical Intermediate for Antiparasitic APIs

    Pharmaceutical manufacturers select 3-Phenoxy-Benzaldehyde as an intermediate in the multi-step synthesis of specific antiparasitic actives such as praziquantel. It contributes the phenoxybenzyl group in the precursor stages, with strictly controlled purity and residual solvent levels to meet pharmacopeial specifications for API intermediates. Facilities integrate analytical QC checkpoints post-condensation to comply with Good Manufacturing Practice (GMP) and pharmacopoeial guidelines. Downstream pharmaceutical production requires exact stoichiometry and full traceability from raw material receipt through to final purification.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP/NF monographs for API intermediates (where applicable)
    • EDQM CEP requirements for regulatory filings
    • 21 CFR Part 211 US cGMP regulation

    Typical usage ratio

    • 0.9 – 1.1 molar equivalent relative to keto acid intermediate; optimized per target reaction conversion and purity monitoring

    Downstream process integration

    • Grignard or aldol condensation with substituted keto acids, followed by hydrogenation and subsequent cyclization, forming the key structural element of antiparasitic APIs

    Final product types

    • Prazquantel (API), additional anthelmintic actives based on phenoxybenzyl scaffolds
    • Tablet and suspension finished dosage forms (pharmaceuticals for human and veterinary use)

    3. Aroma Chemical Synthesis for Fine Fragrances

    Producers of fine aroma chemicals employ 3-Phenoxy-Benzaldehyde as a building block in manufacturing floral and woody fragrance ingredients. Its unique aldehydic profile provides high-impact top notes and backbone for blending in perfume compositions. Aromatics manufacturers precisely dose this aldehyde into controlled batch acetalization or reduction reactions to yield target aroma molecules, maintaining low-odor impurity levels per IFRA and mainstream industry purity criteria. Blending lines require tight batch tracking to assure consistent olfactory properties and allergen control compliant with global fragrance safety standards.

    Industry compliance standards

    • IFRA Code of Practice (International Fragrance Association)
    • EU Cosmetics Regulation (EC) No 1223/2009
    • Global Fragrance Ingredient Standard (RIFM/IFRA)
    • ISO 9235:2013 Natural Aromatic Raw Materials – Guidelines for Aroma Chemical Production

    Typical usage ratio

    • 0.3% – 1.5% (w/w) of total batch composition in downstream aroma chemical synthesis; precise percentage dependent on desired intensity and end-use product concentration

    Downstream process integration

    • Acetalization, reduction, and subsequent blending in aroma chemical reactors, with in-line GC-MS analysis for quality control of organoleptic and purity parameters

    Final product types

    • Fine fragrance intermediates (e.g. floral aldehydes, phenoxy acetal blends)
    • Luxury perfume compounds and personal care fragrance bases

    4. Synthesis of UV-Curable Monomers for Coating Applications

    Advanced coatings and printing ink manufacturers utilize 3-Phenoxy-Benzaldehyde as a precursor in specialty monomer synthesis. It imparts rigidity and UV stability to acrylate or methacrylate monomers, which are subsequently polymerized for high-resistance, low-yellowing coatings. Its controlled addition early in the reaction sequence determines final polymer network density, influencing cured film properties in automotive finishes and high-performance plastics. Downstream quality lab monitors reactant conversion and color index against automotive OEM and electronics sector standards.

    Industry compliance standards

    • ISO 9001 QMS for coating chemicals
    • ASTM D7767-11 (Standard Practice for UV-Curable Coatings)
    • Automotive OEM paint supplier requirements (e.g. Volkswagen TL 226, GM 9984175)
    • RoHS Directive (2011/65/EU) for electronics coatings

    Typical usage ratio

    • 2% – 8% by weight of initial reaction mixture for monomer synthesis; adjusted based on targeted hardness and cross-link density

    Downstream process integration

    • Incorporated through nucleophilic addition or Michael addition to (meth)acrylic acid derivatives prior to polymerization; post-reaction filtration and distillation steps to refine monomer purity

    Final product types

    • UV-curable monomers for industrial coatings
    • High-durability automotive clear coats, specialty inks for PCB and plastic applications
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    Certification & Compliance
    More Introduction

    3-Phenoxy-Benzaldehyde — A Manufacturer’s Perspective

    Bringing Precision and Purity to Modern Chemistry

    For many years, our work with aromatic aldehydes has followed a straightforward principle: don’t cut corners. 3-Phenoxy-Benzaldehyde represents more than just another compound on the production line. Sitting at a crossroad between tradition and innovation, it plays a decisive role in today’s advanced chemical synthesis. Production never stops being hands-on, and every batch demands more than theory—it insists on meticulous handling, raw material control, and a respect for chemistry sharpened by experience at the reactor.

    We list our 3-Phenoxy-Benzaldehyde under the recognized CAS number 39515-51-0. The typical molecular specification, C13H10O2, reflects high purity and a strong commitment to quality: usually, our lots test above 99% by GC analysis, with color and moisture levels held tightly in check. This direct approach to consistency lets us avoid headaches—both for us and anyone downstream relying on a solid starting material.

    Purpose-Driven Manufacturing

    Demand for this aldehyde comes mainly from the agrochemical sector. It anchors several synthesis routes in the development of pyrethroid insecticides—a field that rarely rewards inattention. Skilled chemists understand how the phenoxy group at the 3-position brings about crucial differences: compared with unsubstituted benzaldehyde or simple p-substituted analogues, our material brings higher selectivity, making it a favorite among research teams formulating innovative crop protection molecules.

    Working inside a chemical plant, you quickly learn the difference between numbers on a spec sheet and the reality of scaling up. 3-Phenoxy-Benzaldehyde behaves with a distinctive profile: it brings a faint almond-like odor and appears as a slightly yellow to almost colorless liquid or low-melting solid, depending on ambient temperature and batch storage. Experience tells us to pay attention to even modest impurities—trace byproducts left from phenol etherification steps in upstream synthesis can cast a long shadow on downstream catalysis. That’s why we always push GC-MS and HPLC quality checks past the ‘just acceptable’ mark.

    Our production lines run on practical wisdom: moisture is controlled below 0.1%, as excess water in benzaldehyde chemistry brings risks of side reactions and hydrolytic losses. The boiling point (roughly 331°C under atmospheric pressure) means special care and equipment are needed when distilling or purifying. Even day-to-day handling—protecting drum headspace from air, avoiding light-induced oxidation, or minimizing heat during transfer—calls for a practiced hand. The chemistry is simple in textbooks, but the real world demands much closer attention.

    Reliability in Synthesis — Inside Story

    Anyone in the organic laboratory can tell you: not all aromatic aldehydes behave the same, and each introduces different quirks at the bench. 3-Phenoxy-Benzaldehyde stands apart, mostly due to the electronic influence of its ether linkage coupled with the position on the ring. It’s more stable during storage than some dialdehydes, and inert enough to withstand shipment over long distances without rapid degradation. These details let chemists count on batch-to-batch reliability, whether they’re scaling up synthetic intermediates for pilot-plant trials or preparing a single gram for assay.

    Our colleagues in process engineering often remind us that subtle changes—residue left in a jacketed vessel, a tricky phase change on the drier, a humidity spike during storage—can snowball into something costly down the line. Keeping a close eye on melting point, color (APHA below 25), GC purity, water content, and even odor reflects the reality: most high-value syntheses have little room for rework and can’t afford to chase hidden flaws in starting materials.

    The Role of Transparency and Track Record

    Online catalog spec sheets rarely show the messy side of manufacturing. Take our own records: we track stepwise production yields, log details from laboratory scale to several-thousand-liter reactors, and maintain impurity profiles on every shipment. Regular audits catch problems early.

    Over the years, several multinational partners have audited our processes, laboratories, and storage. They care about every detail—from drum sealing integrity to batch documentation. Over dozens of shipments, we’ve met requirements for traceability, regulatory assurance, and hazardous goods compliance. Our records show this story: real consistency comes from never skipping small things.

    On rare occasions, customers flagged batches for faint color changes or odor deviations. Tracing the cause, we addressed unexpected air ingress during filling, or caught early-stage contamination in the feedstock. These moments strengthen our understanding, not only by reinforcing tighter controls, but by improving our communication with clients’ technical teams. We log every issue and solution for both process improvement and transparency.

    Beyond Commodity Chemicals — Application Experience

    In our daily work, 3-Phenoxy-Benzaldehyde rarely gets treated as a simple raw material. Once it leaves the factory, it might serve dual roles—one batch destined for technical intermediates, another for research synthesis in a global agrochemical pipeline. Downstream users value its performance in Grignard reactions, nucleophilic additions, and condensation chemistry. Some research teams adapt it for advanced ligand synthesis, leveraging the phenoxy group’s influence over reactivity and steric profile.

    In the lab, this aldehyde functions as a valuable building block for creating pyrethroid scaffolds. Even outside large-scale crop-protection chemistry, medicinal chemists sometimes pick it for library synthesis, pursuing unique aromatic frameworks and fine-tuning their molecules’ biological properties. We've supported projects in applied materials too, where 3-Phenoxy-Benzaldehyde’s aromatic backbone serves as a precursor for specialty polymers and resin modifiers, giving end-products improved rigidity or thermal properties.

    Veteran chemists recognize its comparative advantages: greater selectivity vs. p-phenoxy analogues when targeting certain synthetic transformations, and generally fewer issues with oxidation or peroxidation during storage. Unlike simple benzaldehydes, the phenoxy substitution at the 3-position often tips the balance towards preferred yields and cleaner reaction products.

    Challenges—What Factories Actually Face

    No plant environment is free from challenge. Sourcing raw phenols of consistent quality, controlling reaction exotherms on etherification steps, and minimizing off-gas and effluent waste streams force us to adapt and improve working practices. Production teams must be nimble—the smallest abnormality in temperature can prompt runaway side reactions, discoloration, or yields dipping below cost-effective thresholds.

    Worker safety and environmental stewardship demand more than procedural checklists. We engineer our installations to keep exposure under tight limits, supply all operators with full PPE and closed-system transfer lines, and maintain real-time monitoring for any emissions or leaks. Our technical team regularly revisits green chemistry guidelines and upgrades processes to reduce residual byproducts and VOC emissions. These choices don’t just tick boxes—they build the trust that keeps long-term customers close.

    Waste management stands as one of the costliest and most crucial aspects. We install solvent recovery systems to minimize flammable waste production, and recycle process solvents when possible. Batch records detail everything from solvent use to water treatment outputs, supporting both internal audits and customer inquiries.

    Standing Out—What Makes 3-Phenoxy-Benzaldehyde Special

    Direct experience has honed our respect for the difference one molecule can make. Unlike close cousins such as 4-phenoxybenzaldehyde or unsubstituted benzaldehyde, this 3-position analog offers a carefully tuned profile: its electronic properties lend higher selectivity, making it irreplaceable in certain synthetic procedures that demand precision over brute force.

    Chemists report fewer side products in pyrethroid syntheses versus various positional isomers. The phenoxy group’s subtle effect stabilizes the aromatic ring but does not hamper reactivity at the aldehyde carbon. Controls for color and clarity resist rapid breakdown due to oxidation, compared with more vulnerable analogs. For those who value the details, our refinement process aims not just for compliance, but above-market purity and clarity, batch after batch.

    Quality assurance flows straight from manufacturing to application. Tech staff run in-house verifications and log every lot’s physical properties—appearance, melting or freezing point, odor profile, and GC-MS fingerprints. Customers depend on this paper trail, whether they are producing metric tons or just pilot-scale libraries. When an issue does arise, we chase it to the source, document corrective action, and keep the lines of communication open. Trust builds from visible performance, never from marketing talk alone.

    Supporting Real-World Innovation

    Even as trends in chemistry change, our manufacturing priorities don’t. Conserving purity, controlling batch-to-batch variability, and catching side reactions before they become problems form the backbone of our process. Downstream users—R&D teams, process engineers, and pilot plants—rely on a stable and documented supply to keep innovation alive.

    Academic teams sometimes reach out seeking advice on the best way to convert or derivatize our product for new applications. Shared knowledge grows both business and the broader scientific community. Where projects ask for deeper insight—whether on solvent interactions, reactivity with specific nucleophiles, or controlling exotherms in multi-kilogram reactions—we offer real working notes, not just generic advice. Time on the factory floor has taught us that such shared experiences support long-term progress.

    Our plant engineers embrace continuous improvement—testing alternative methods to recover heat, streamlining solvent cycles, and investigating greener reagents when updating equipment or processes. Suppliers and customers value our transparency in sharing both setbacks and breakthroughs. This openness fuels incremental gains that add up in real product consistency and safer operations.

    Solutions—Managing Supply, Risk, and Change

    Stable supply chains depend on forecasting, safety stocks, and clear logistics. We maintain raw material reserves, ensure rapid sample turnaround, and document every transfer for traceability. These habits lessen disruptions caused by trade shifts, port slowdowns, or unforeseen supply hiccups.

    Quality-related risks occupy our engineering and management conversations. We run long-term stability studies, validate shipping containers for evaporation losses, and periodically retrain staff in best-practice handling. Priority shipments double-boxed and sealed under nitrogen illustrate our belief that even small variables can tip the scales between ease and havoc for a customer.

    In scale-up, the road from lab to plant always brings surprises: what flowed smoothly in 100g reactions gives new hurdles at 100kg—mixing rates, heat dissipation, filtration efficiency. We’ve learned from experience that honest feedback, open records, and active troubleshooting make up the difference between recipe and repeatable success.

    We back emerging application areas by partnering with users to adapt 3-Phenoxy-Benzaldehyde to new requirements—investigating custom purifications, particle size management, or tailored packaging. Some upstream partners in biotechnology request ultra-low metal residues, so we optimize washing and filtration. For those focused on sustainability, we support solvent recycling and waste minimization in finished formulations, leveraging our plant’s real-world knowhow.

    Looking Ahead—Sustaining Consistency and Value

    Making high-grade chemical intermediates in the real world means tackling one problem at a time, planning for the unexpected and respecting the craft behind each drum that leaves the gate. In our teams, pride grows out of this process—colleagues pass down lessons, troubleshoot design tweaks, and obsess over batch records because they know customers notice those small details.

    Professional users expect more than a list of technical data—they ask how their supply is managed, what happens if batches deviate, and how issues get addressed. We answer these questions not by hiding behind certificates but by sharing experience, opening up our operations to audits, and delivering on every promise, shipment after shipment.

    3-Phenoxy-Benzaldehyde has gained a stable reputation among those who depend on its reactivity and consistency. Its niche role—serving as the backbone for vital agrochemical and potential pharmaceutical routes—gives us a reason to keep refining, improving, and strengthening our approach. Most of all, we stay committed to honest conversation, rigorous testing, and building the trust that backs every application, whether in research, commercial production, or the next generation of innovation.