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3-Methylcinnamic Acid

    • Product Name 3-Methylcinnamic Acid
    • Alias β-Methylcinnamic acid
    • Einecs 209-027-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    269380

    Cas Number 5827-19-2
    Molecular Formula C10H10O2
    Molecular Weight 162.19 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 58-61 °C
    Boiling Point 300 °C (estimated)
    Density 1.129 g/cm3
    Solubility In Water Slightly soluble
    Purity Typically >= 98%
    Synonyms 3-Methylcinnamic acid, m-Methylcinnamic acid
    Iupac Name 3-Methyl-3-phenylprop-2-enoic acid
    Flash Point 110 °C
    Storage Conditions Store at room temperature, dry and well-ventilated area
    Refractive Index 1.576 (predicted)
    Smiles CC1=CC=CC=C1C=CC(=O)O

    As an accredited 3-Methylcinnamic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of 3-Methylcinnamic Acid, labeled with chemical name, CAS number, hazard pictograms, and handling instructions.
    Shipping 3-Methylcinnamic Acid is shipped in tightly sealed containers to prevent moisture and contamination. It must be stored and transported in a cool, dry place, away from incompatible substances. Proper labeling and adherence to local regulations are required. Personal protective equipment is recommended during handling to ensure safety.
    Storage Store 3-Methylcinnamic Acid in a tightly closed container, away from moisture and direct sunlight. Keep it in a cool, dry, and well-ventilated area, ideally at room temperature. Avoid contact with strong oxidizing agents. Ensure good labeling and secondary containment to prevent spills or accidental contamination. Use appropriate personal protective equipment when handling this chemical.
    Application of 3-Methylcinnamic Acid

    Applications of 3-Methylcinnamic Acid in Industrial Manufacturing

    As a direct producer, we supply 3-Methylcinnamic Acid to multiple high-value manufacturing segments. Our experience supports advanced formulation and process requirements, backed by global regulatory compliance and quality monitoring for every shipment.

    1. Pharmaceutical Intermediate for Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

    Active pharmaceutical manufacturing relies on 3-Methylcinnamic Acid as a key intermediate for synthesizing several arylpropionic acid derivatives. R&D and commercial production scale-up use it in the condensation reaction steps, enabling reliable yields and impurity management. Its aromatic structure helps chemists achieve controlled substitution on the propionic acid backbone, critical for selective NSAID APIs. During process validation and commercial lot production, QC implements identification and purity protocols linked to drug master files.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • US Pharmacopeia (USP) monographs for intermediates
    • EU GMP Part II guidelines
    • Certificate of Suitability (CEP) dossier support, where required

    Typical usage ratio

    • 0.3–2.0 molar equivalents in active intermediate synthesis, adjusted for product and side-reaction control

    Downstream process integration

    • Entry at aryl condensation or esterification step
    • Pilot to commercial scale batch reactors
    • In-line HPLC and GC analysis during process
    • Purified for further reaction in API finishing

    Final product types

    • Ibuprofen intermediates
    • Naproxen intermediates
    • Other custom NSAID active ingredients
    • Finished oral and topical pharmaceutical formulations

    2. Fragrance and Flavor Ingredient in Aroma Chemicals Manufacturing

    Manufacturers of synthetic aromatic and flavor chemicals use 3-Methylcinnamic Acid as a direct precursor or modifier in the reaction path for fine fragrance molecules. Its methyl-cinnamate moiety imparts a natural, balsamic note, suitable for controlled esterification and reduction to produce esters and aldehydes. Rigid QC supports compliance with food-grade specifications, and automated process dosing ensures consistent batch-to-batch performance.

    Industry compliance standards

    • IFRA Code of Practice
    • FDA 21 CFR 172.515 (Flavoring Substances and adjuvants)
    • ISO 9235 for aromatic raw materials (where applicable)
    • Food Chemicals Codex (FCC) acceptance

    Typical usage ratio

    • 0.1–0.8% by weight in finished aroma chemicals
    • Concentration calibrated to intensity, matrix compatibility, and regulatory maximums

    Downstream process integration

    • Addition at aroma intermediate synthesis
    • Catalytic esterification to methyl or ethyl derivatives
    • Vacuum distillation for pure end-use forms
    • QC release on color, purity, and organoleptic profile

    Final product types

    • Methyl-3-methylcinnamate (fragrance base)
    • Niche floral and balsamic perfumery accords
    • Flavor compounds for confectionery and bakery
    • Liquid fragrance compositions for consumer products

    3. UV-Absorber Precursor in Polymer Additives Production

    Chemical additive manufacturers incorporate 3-Methylcinnamic Acid in the synthesis of cinnamate-based UV absorbers for plastics and coatings. The methyl substitution enhances light-stabilizing properties, enabling efficient protection of polymer matrices from photodegradation. In-house and downstream QC validate integration within extrusion or mixing lines, and additive formulators adjust ratios for compatibility with polyolefins, PVC, and engineering plastics. Production adheres to rigorous industrial safety protocols and environmental management for additive processing.

    Industry compliance standards

    • REACH registration for chemical raw materials
    • RoHS Directive 2011/65/EU for restricted substances
    • ISO 9001 production and QC documentation
    • OECD guidelines for safety and environmental impact

    Typical usage ratio

    • 0.05–0.5% by weight in masterbatch or direct additive formulations
    • Variant loading based on polymer type and targeted UV resistance index

    Downstream process integration

    • Co-extrusion or melt blending during plastic compounding
    • Batch dosing to coating resins pre-curing
    • Dry blend or liquid addition for in-process polymer protection
    • Quality monitoring for light transmission and weathering resistance

    Final product types

    • UV-stable plastic sheets and films
    • Outdoor-grade automotive polymer parts
    • Decorative and protective industrial coatings
    • Sunblock or sunscreen film layers

    4. Organic Synthesis Intermediate for Agrochemical Actives

    Leading agrochemical companies use 3-Methylcinnamic Acid as an intermediate reagent for synthesizing herbicide and fungicide active ingredients. Selective hydrogenation and controlled substitution steps leverage its reactivity profile, supporting cost-efficient scale-up from kilogram to multi-ton batches. Traceability covers all shipments, meeting crop-protection industry demands for impurity control and batch documentation aligned with the latest regulatory dossiers.

    Industry compliance standards

    • FAO/WHO Guidelines on Specification Requirements for Plant Protection Products
    • ISO 17025 QC laboratories
    • REACH compliance for active ingredients
    • Country-specific crop protection regulations (EPA, EU, etc.)

    Typical usage ratio

    • 0.25–1.5 molar equivalents in key active synthesis routes
    • Ratio tailored to target active and side-chain modifications

    Downstream process integration

    • Precursor addition during oxidative coupling or hydrogenation
    • Continuous-feed reactor dosing for bulk production
    • Purification and crystallization for intermediate isolation
    • Analytical confirmation using GC-MS and NMR

    Final product types

    • Phenoxy acid herbicide intermediates
    • Novel fungicide base compounds
    • Crop protection concentrates
    • Ready-to-apply agrochemical formulations

    5. Precursor in Dye and Pigment Synthesis for Specialty Colorants

    Specialty dye manufacturers use 3-Methylcinnamic Acid as a building block for synthesizing hydrophobic dyes and pigment dispersions. Its aromatic and unsaturated structure enables integration in azo coupling and condensation routes for high-performance colorants. Custom batch orders often require strict impurity limits, supported by full traceability and consistent supply for industrial textile, ink, and plastic colorant applications.

    Industry compliance standards

    • ZDHC (Zero Discharge of Hazardous Chemicals) for dyes
    • OEKO-TEX 100 for textile colorants
    • ISO 787-24 for pigment testing
    • Product Safety Data Sheet (SDS) conformity

    Typical usage ratio

    • 0.2–1.2 molar equivalents in dye and pigment synthesis
    • Range determined by chromophore structure and application end-use

    Downstream process integration

    • Entry at diazotization or coupling reaction
    • High-shear mixing or solvent suspension systems
    • Spray drying or filtration post-synthesis
    • Batch QC for hue, solubility, and fastness

    Final product types

    • Azo and anthraquinone dyes for technical textiles
    • Water-insoluble pigment concentrates
    • UV-stable colorant batches for inks and coatings
    • Performance plastics color masterbatches
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    Competitive 3-Methylcinnamic Acid prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    3-Methylcinnamic Acid: Practical Chemistry for Real-World Solutions

    Getting to the Heart of 3-Methylcinnamic Acid

    Our experience running production halls and laboratory benches has shaped every step in our synthesis of 3-Methylcinnamic Acid. Craftsmen in chemical manufacturing can spot the difference the moment a batch is poured out. The scent, purity, and solid form all matter, and each tells a story about how the product was made and how it will perform in demanding applications. Chemists who’ve worked with cinnamic acid derivatives understand that subtle shifts in molecular shape, position of the methyl group, and even the specific crystallization process impact downstream results.

    The molecule, with the formula C10H10O2, stands slightly apart from the common cinnamic acid due to the methyl group on the third carbon. That change gives more than academic interest: it influences reactivity, melting behavior, solubility in solvents, and even how it smells. Three percent impurity, inconsistent melting, or unwanted color can sink entire production runs for fragrance, pharmaceutical, or specialty flavor customers. Some of our colleagues who use 3-Methylcinnamic Acid in coumarin synthesis, for example, have told us stories about wasting overnight runs because the crystals had tenacious tints or harsh overtones in the aroma profile. We have spent long nights listening to those tales and taken them back to the plant floor to craft a process that responds directly to these needs.

    From Raw Materials to Targeted Properties

    Raw material selection matters. We have stood on receiving docks under early morning lights, rejecting drums of raw toluene that carried too many unknowns. Only with trustworthy feedstock and every charge measured meticulously, do we move toward the condensation step that produces 3-Methylcinnamic Acid in a form trusted by formulators worldwide. The methyl group in the meta-position, as opposed to ortho or para, does not just subtly shift the spectrum—it creates a molecule better suited for some transformations and reactions adrift or prone to side-product formation.

    We have standardized our 3-Methylcinnamic Acid to purity levels greater than 99 percent. This threshold emerges not from arbitrary specification, but through years of tight feedback from R&D clients, flavorists, and pharmaceutical intermediates plants who rely on batch-to-batch reliability. Partners recount scenarios where 96–97 percent acid led to sticky solids, off-white powder, and poor batch-to-batch reproducibility. By dialing in our crystallization, we bring out fine, easy-to-handle crystalline powder with a clean melting point. Qualitative details—like appearance, smell, and free-flowing consistency—might seem minor until they clog a feeder in a high-output mixer or spoil a fragrance pilot blend after hours in the reactor.

    Applications That Demand Precision

    A major portion of our production finds its way into pharmaceutical intermediates. At this bench, accuracy counts. 3-Methylcinnamic Acid serves as a precursor for several specialty drugs and fine chemical intermediates. Process engineers depend on precisely measured, consistently pure inputs to prevent surprises during condensation or amidation. Off-specification acid can introduce color bodies, alter pH, or even led to failed crystallization in subsequent syntheses. Our material has enabled customers aiming for narrow impurity profiles—where even residual solvents or trace metals threaten downstream reactions—to rest easy, as our internal checks clear much tighter margins than most commodity offerings.

    Flavor & fragrance artisans use this acid both for direct blending and as a key building block. Methyl substitution brings a gentle twist to traditional cinnamon and balsamic notes, offering product designers more options than standard cinnamic acid. We’ve seen perfumers and food chemists attract loyal buyers because their formula has the subtlest shift in profile—something only possible when the ingredient comes without “background noise” from chemical traces or off-colors. The methyl group’s exact positioning dramatically shifts aroma, so variants like 2- or 4-methylcinnamic acid will not offer the same warmth or roundness sought by leading cosmetic blenders and high-end food brands.

    Why Differences in Isomers Matter

    Colleagues often ask us how the 3-methyl version differs in real-life usability from 2- or 4-methylcinnamic acid. While this may seem like a minor academic distinction, from a synthetic or flavor perspective, the impact is substantial. The orientation of the methyl group on the aromatic ring influences not just the physical shape but the way reactants interact. We have run side-by-side melt tests and monitored esters formed from each isomer—batch yields, reaction rates, and purity shift dramatically.

    3-Methylcinnamic Acid offers better selectivity for certain electrophilic aromatic substitutions versus its 2- and 4-methyl siblings. Chromatograms don’t lie: less byproduct, tighter peaks, and fewer purification headaches downstream. Even the esterification step, common in fine aroma compound synthesis, produces more consistent outcomes. These differences aren’t theoretical—they become clear every time we run pilot batches and compare yields. Manufacturers of high-value aroma chemicals or intermediates know that a one-size-fits-all approach doesn’t work. Blindly swapping another isomer ends up inviting remediation steps, rework, or lost revenue.

    Real-World Specifications and the Reason Behind Them

    Manufacturing isn’t a white-paper exercise; we see real-world factors at every step of scale-up. So, our technical team believes in spelling out what matters: purity, appearance, and consistency. Our material typically appears as a white to off-white crystalline powder, easily handled by automated feeders yet resilient to atmospheric moisture—critical in open handling environments. Moisture sensitivity runs low, so the material remains free-flowing during production shifts and large-scale decanting.

    Melting point ranges matter for more than regulatory data. Our careful crystallization yields a substance melting consistently in the correct range, giving buyers confidence for direct use or further processing. During a project with a flavors client, several tons destined for food-safe applications delivered under tight timeframes. The technical manager shared that any lags or clumping from off-spec product would have thrown off a week’s output or forced expensive rework. We know these time, cost, and quality pressures, so every batch is tracked and re-verified before packing out. This rigor explains why clients have relied on our acid for more than just spot or intermittent supply—they trust it over years, through scale-ups and process changes.

    What Sets 3-Methylcinnamic Acid Apart in Production Settings

    Some generic suppliers treat cinnamic acid derivatives as mere commodities, but real-world chemistry punishes that mindset. We’ve run trials with competitor batches, faced unexpected performance drops in esterifications, seen lower yields in reactive distillations, and listened to technicians describe the extra hours spent cleaning out clogged lines from sticky, inferior powder. There’s a measurable cost to “almost pure” in production: feeding jams, uneven reactions, or more labor during maintenance shutdowns. With 3-Methylcinnamic Acid, every step—starting with high-purity input, through filtration and drying—signals investment in real-world usability for those running actual facilities.

    Variance in particle size or modest variations in composition force manufacturers into frequent adjustment, costing both time and money. Our process emphasizes reproducible, clean crystals, with minimal fines or oversized pieces, to assure reliable flow rates and dissolving during any scalable protocol. Only this approach keeps things predictable for end-use teams handling flavors, fragrances, and pharma intermediates—areas where trial-and-error wastes more than it saves.

    Supporting Industry Demands Beyond the Lab

    Our teams interact daily with professionals well beyond academic chemistry—maintenance planners, production engineers, R&D innovators, and quality assurance leads. Each uses technical feedback to guide next steps. Over the years, a customer working in next-generation UV absorbers shared that our 3-Methylcinnamic Acid gave them critical performance consistency, supporting a change in product formulation without sourcing headaches. Stability in supply helps our partners stay on schedule and keep their own lines running, avoiding the pinch points that drive up costs.

    Careful batch traceability and transparent quality data provide partners with confidence to maintain regulatory compliance, especially those operating under food, cosmetic, or pharma laws. The world of audits, inspections, and ingredient transparency demands not just a certificate but real, walk-the-floor traceability back to original materials and production logs. Labs looking to certify formulations appreciate being able to confirm process details and see a real commitment to reliability.

    Responsible Manufacturing for Reliable Chemistry

    We believe long-term partnerships start with trust—honest feedback about strengths and challenges, real transparency in specification, and reliability batch after batch. Scaling from lab to tonnage production presents unexpected problems: sticking, slow dissolving, environmental discharge, and even batch-to-batch color changes. We’ve worked closely with customers to adjust our own crystal size or drying cycles to address those issues, sometimes on short notice, and treat every scenario as a partnership rather than a simple transaction.

    Experienced teams know how poor-quality bulk acids can lead to frequent re-cleaning cycles and short-lived process runs. Consistent form and purity mean less downtime and more predictability for operators, freeing up resources to tackle new projects instead of troubleshooting recurring problems. We work with technical managers to supply supporting data for validation runs, and to help meet evolving supply chain or regulatory expectations.

    Practical Differences from Other Cinnamic Acid Derivatives

    Some chemists wonder whether 3-Methylcinnamic Acid delivers truly unique traits compared to the more common, unmodified cinnamic acid or the 2- and 4-methyl analogs. In our hands, differences show up plainly across yield, downstream versatility, and final product properties. The meta-methyl group’s role becomes most apparent during synthetic upgrades—specific cyclizations or substitutions that would show side reactions or impurity buildup with other isomers. We have run enough trials with alternate methyl substitutions to see how even minor deviations lead to lower output or challenging separation steps in multi-stage syntheses.

    Pragmatically, the aroma and solubility characteristics of 3-Methylcinnamic Acid suit specialized needs in perfumery or food flavoring. Some flavor houses have shared that their signature products could only be delivered with the precise nuance delivered by the meta-methyl group, as shifting that group spoils the desired note or distorts the intended mouthfeel. Other industries, including polymers and coatings, appreciate the consistency of melt and low impurity load, which translates to repeatable performance in large-scale, automated facilities.

    Continuous Improvement: Listening and Adapting

    A manufacturer’s job does not end at the loading dock. Our teams check in with users after each delivery, seeking feedback about packaging, handling, and on-line performance. In one case, a customer using our product in a pharmaceutical intermediate faced clumping issues with other vendors’ supplies, which led to bottlenecking in their feeder lines. Together, we looked at alternate drying and sieving protocols to increase flowability and reduce downtime, customizing the batch for their unique set-up and capacity needs. The goal was more than fixing a symptom—we worked to understand the processing steps, right down to how operators handled the acid across different seasons.

    Another partner working in a new fragrance composition found that switching away from lower-grade supply let them dial in aroma components, stabilize shelf life, and secure repeat orders. We keep such conversations active, ready to adjust our operating parameters or offer technical support for troubleshooting. No large-scale process stays static—batch scale, storage conditions, climate, and even customer base change constantly. We expect and encourage this feedback loop, viewing it as a vital part of robust chemistry supply.

    3-Methylcinnamic Acid in a Global, Evolving Industry

    Across fragrance, flavor, and pharmaceutical fields, the expectations around quality, traceability, and responsible production keep rising. As a producer, we recognize our responsibility extends much further than a purity certificate. Teams in quality, procurement, and regulatory affairs rely on us to prove our commitment through routine stability trials, full process visibility, and immediate technical support. Open records, prompt answers, and reliable backup samples build the foundation for new innovations and help our customers meet evolving regulatory expectations.

    Many partnerships span years and continents, with changing compliance requirements driving new documentation or method validation steps. Our teams internally maintain detailed production records and provide open technical dialogue, enabling smooth approvals for both emerging start-ups and established global players. We encourage open exchange with end-user teams—not just procurement officers—so everyone who encounters our 3-Methylcinnamic Acid in their own labs, lines, or final products gets the reliability and insight they deserve.

    Looking Forward With Confidence

    Chemistry is not built on slogans; it is shaped by every batch, every tonne, every operator’s shift, and every client’s morning. We see each use of 3-Methylcinnamic Acid as a reflection of our own standards, choices, and ongoing commitment to real-world, high-value production. Team-to-team feedback and active collaboration remain at the center of how we manufacture and deliver this specialty acid. Deeper understanding of how a subtle molecular change, reliable process control, and close communication influence performance in actual products and plants inspires us to maintain strict controls, open practices, and active technical support for every partner—now and for years ahead.