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3-Methylbenzyl Chloride

    • Product Name 3-Methylbenzyl Chloride
    • Alias m-Chloromethyl toluene
    • Einecs 202-472-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    123586

    Productname 3-Methylbenzyl Chloride
    Casnumber 620-21-1
    Molecularformula C8H9Cl
    Molecularweight 140.61
    Appearance Colorless to pale yellow liquid
    Boilingpoint 206-208 °C
    Meltingpoint -40 °C
    Density 1.075 g/cm3 at 25 °C
    Refractiveindex 1.541
    Flashpoint 91 °C (closed cup)
    Solubilityinwater Insoluble
    Purity Typically >98%
    Synonyms m-Toluyl chloride, 1-(Chloromethyl)-3-methylbenzene
    Storage Store in a cool, dry, well-ventilated area

    As an accredited 3-Methylbenzyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500g amber glass bottle securely sealed, labeled “3-Methylbenzyl Chloride,” featuring hazard symbols, product information, and batch number.
    Shipping 3-Methylbenzyl chloride should be shipped in tightly sealed containers, labeled according to hazardous material regulations. Transport in a well-ventilated vehicle, away from heat, sparks, and incompatible substances. Ensure compliance with local, national, and international shipping guidelines for toxic and corrosive chemicals. Safety documentation must accompany the shipment.
    Storage 3-Methylbenzyl chloride should be stored in a tightly sealed container, in a cool, dry, well-ventilated area away from moisture, heat, and sources of ignition. Keep it away from strong oxidizing agents and acids. Store under inert atmosphere (like nitrogen) if possible, and protect from light. Ensure proper labeling, and use secondary containment to avoid spills or leaks.
    Application of 3-Methylbenzyl Chloride

    Applications of 3-Methylbenzyl Chloride in Industrial Manufacturing

    3-Methylbenzyl Chloride serves as a specialist intermediate in multiple industrial sectors, offering unique reactivity for the synthesis of advanced chemical products. All applications listed below are based on real-world manufacturer experiences, established production routes, and verified client usage across the chemical industry’s core downstream markets.

    1. Pharmaceutical Intermediates Synthesis

    Pharmaceutical ingredient manufacturers incorporate 3-Methylbenzyl Chloride during the construction of key intermediates required for antihypertensive agents, antifungal drugs, and certain CNS-active compounds. Its selective benzylation capacity enables the functional group modifications essential for building complex active pharmaceutical ingredients, facilitating precise molecular tailoring during multi-step organic synthesis campaigns.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP), ICH Q7
    • Pharmacopoeia references: USP, Ph. Eur., JP as applicable for intermediates
    • REACH Regulation (EC) No 1907/2006 (for import/use in the EU)
    • Local APIs/intermediate registration requirements (SFDA, USFDA as relevant)

    Typical usage ratio

    • 0.8–1.2 molar equivalents per mol of core substrate, adjusted based on the targeted intermediate and desired selectivity

    Downstream process integration

    • Introduced in the alkylation or benzylation step after initial core framework assembly, followed by purification and subsequent derivatization reactions

    Final product types

    • Generic API intermediates for antihypertensive drugs
    • Azole antifungal precursors
    • Intermediate compounds for CNS drug research

    2. Agrochemical Intermediate Production

    Major agrochemical groups specify this compound as a key chlorinated benzylating agent for synthesizing intermediates in selective herbicide, insecticide, and fungicide analogues. It allows introduction of methylbenzyl functionality, supporting safer and more biodegradable profiles in the final organochemical formulations through controlled C-aryl functionalization.

    Industry compliance standards

    • FAO/WHO pesticide specifications
    • ISO 9001:2015 Quality Management for agrochemical sites
    • REACH Annex XVII restrictions on hazardous intermediates
    • Globally Harmonized System (GHS) for labelling and transport

    Typical usage ratio

    • 1.0–1.5 molar equivalents per mol of base amine or phenol, dependent on targeted reaction pathway and further substitution steps

    Downstream process integration

    • Charged during Stage II–III of multi-step synthesis, prior to cyclization or heteroatom incorporation and final formulation blending

    Final product types

    • Selective herbicide intermediates
    • Insecticide building blocks
    • Fungicide precursor molecules

    3. Fragrance and Aroma Chemicals

    Producers of specialized aroma compounds exploit the compound’s reactivity for developing novel benzyl-substituted aldehydes and alcohols, which act as character impact ingredients in fine fragrance bases and flavor concentrates. Its introduction enables fine-tuning of olfactive profiles, particularly in spicy, anisic, and woody accord formulations, allowing for consistent batch-to-batch olfactory standards required by global perfumery clients.

    Industry compliance standards

    • IFRA (International Fragrance Association) Code of Practice
    • FCC (Food Chemical Codex) for food-grade derivatives
    • ISO 9235:2013 (Aromatic natural raw materials)
    • EU Regulation 1223/2009 (Cosmetics Regulation)

    Typical usage ratio

    • 0.3–0.6 molar equivalents relative to the aldehyde or alcohol base, tuned for target intensity and regulatory residue limits

    Downstream process integration

    • Applied during the alkylation or acylation steps of aroma compound synthesis, prior to distillation and admixture into finished aroma blends

    Final product types

    • Spicy-floral perfume bases
    • Woody-aldehydic fragrance components
    • Flavoring agents for beverages and confections

    4. Polymer Modifier and Additive Manufacture

    Producers in specialty polymer sectors leverage this compound as a functionalization agent for grafting or crosslinking during the manufacture of ionic liquids, surfactant monomers, and high-performance resins. Its selective reactivity assists in controlling polymer branching, thermal properties, and surface compatibility, especially for engineering thermoplastics and elastomer enhancements.

    Industry compliance standards

    • ISO 9001:2015 for polymer processing facilities
    • RoHS Directive 2011/65/EU (for electronics-related polymers)
    • UL 94 flammability ratings (if applied in electrical components)
    • REACH compliance for monomer/additive traceability

    Typical usage ratio

    • 0.5–1.0% w/w as a co-monomer or chain modifier; exact percentage varies according to polymer matrix and desired property modification

    Downstream process integration

    • Incorporated into the polymerization or post-polymer modification stage, commonly via solution or melt blending, prior to extrusion, molding, or film casting

    Final product types

    • Cationic surfactant-modified polymers
    • Customized engineering plastics
    • Elastomer blends with improved compatibility or antistatic performance

    5. Dye and Pigment Intermediate Synthesis

    Colorant and pigment manufacturers select 3-Methylbenzyl Chloride as a targeted benzyl source for introducing methyl-substituted aromatic rings in azo and triarylmethane dye matrixes. This addition improves chromatic properties, solubility, and fastness, meeting the demands of high-end textile, ink, and plastic coloration processes where specific shades and dispersibility are essential.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (for textile dyes)
    • EN 71-3 (EU safety of toy dyes/pigments)
    • ISO 787/1:1981 (General test methods for pigments and extenders)
    • REACH registration of dye intermediates

    Typical usage ratio

    • 0.9–1.3 molar equivalents per aromatic amine or phenolic precursor, optimized based on desired color depth and fastness requirements

    Downstream process integration

    • Employed at the functionalization phase prior to the final diazotization or coupling step of dye synthesis, followed by purification and dye formulation

    Final product types

    • Methylated azo dyes for textile applications
    • Triarylmethane-based pigment intermediates
    • Ink and plastic colorants with enhanced dispersibility
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    Certification & Compliance
    More Introduction

    Introducing 3-Methylbenzyl Chloride: Our Driven Experience in Specialty Chemicals

    Open Up Opportunities with 3-Methylbenzyl Chloride

    We have watched shifts in the chemical sector over the years, seeing clients and researchers turn their attention to compounds that shape countless innovations. Among them, 3-Methylbenzyl Chloride stands out as a staple intermediate that provides reliable reactivity for complex synthesis. Within our plant walls, years of hands-on adjustment and feedback have built a product that doesn’t just meet a technical definition—it solves real bottlenecks in daily lab and industrial settings.

    Understanding What Makes Our 3-Methylbenzyl Chloride Unique

    We produce 3-Methylbenzyl Chloride as a clear, colorless to pale yellow liquid, carrying the unmistakable, pungent scent characteristic of alkyl chlorides. Its chemical structure, C8H9Cl, points to a methyl group attached to the benzyl ring in the meta position. Over time, our operators have learned that even small adjustments in purification steps have a direct effect on downstream product yields for our partners. Nobody wants trace byproducts in active pharmaceutical ingredient syntheses or resin modifiers, so we track every batch closely for purity—typically no less than 99% by GC—and moisture content.

    We have learned, through endless customer feedback, that unreliable chlorination or careless separation can lead to headaches down the line. So we strip back excess toluene, keep chloride impurities minimal, and put effort into managing odor control to support compliance with workplace safety protocols. There’s always a tradeoff between production speed and careful distillation, but we have drawn a line: we will not rush the finish if it means risking the batch’s integrity.

    Meeting Demands Beyond Bulk Supply

    Neighbors in the aromatic intermediates sector often face similar frustrations—reactivity, selectivity, and storage. We’ve fielded calls from research chemists stuck with mixed isomer stocks or poor quality feed. Experience tells us that a consistent product profile frees our clients to focus on core chemistry, not troubleshooting. We designed our 3-Methylbenzyl Chloride process to minimize color development and stabilized it to resist oxidation and hydrolysis under proper storage. Our product comes packed in steel drums and HDPE containers suited for both bulk consumption and laboratory-scale experiments, ensuring ease of handling whether a drum or a small-scale lot is needed.

    How 3-Methylbenzyl Chloride Makes a Difference in Synthesis

    This compound earned its place in the toolbox of pharmaceutical and agrochemical manufacturing, thanks to the combination of the benzyl function with ortho, meta, or para substitution. With the methyl group in the meta position, reactivity takes on a distinct course—nucleophilic substitution becomes easier to control, leading to higher selectivity in key steps. We have supplied 3-Methylbenzyl Chloride to projects focusing on selective etherifications and esterifications. Our team has seen firsthand how subtle differences in isomer structure shift outcomes in final products—yield, isomeric purity, even physical properties of end compounds.

    No two customer stories are quite the same. While some focus on scale-up processes for active drug intermediates, others are engaged in flexible polyurethane production or custom dye manufacturing. In every setting, control over alkylation and subsequent reactions spells the difference between a successful production week and wasted resources. We did not learn this in theory but received it directly from chemists running pilot lots and small-scale campaigns. Our careful approach to chlorination and distillation permits sharper control in these downstream transformations.

    Setting Ourselves Apart: 3-Methylbenzyl Chloride Versus Alternatives

    We often receive questions about how our 3-Methylbenzyl Chloride stacks up against para- or ortho-substituted benzyl chlorides, or even standard benzyl chloride. Chemical nuance matters here. The meta methyl group alters boiling point, solubility, and reaction selectivity. We have measured subtle shifts in behavior during Friedel–Crafts reactions or for the introduction of functional groups such as nitriles or esters. By comparison, the para- and ortho-isomers exhibit different electronic effects on the aromatic ring, which become critical when precise control is demanded in multi-step syntheses.

    We do not claim that one compound will completely replace another. Our work with custom projects—especially in specialty polymers or as building blocks for advanced fine chemistry—shows that end-use requirements shape the selection. Still, one chief advantage of sourcing from an experienced producer is the technical dialogue we sustain. Chemists know we document our analytical results tightly, year after year. Our quality control history supports regulatory needs, whether for pharmaceuticals, agricultural chemicals, or performance materials.

    Safety in Handling and Application

    Years of plant operation taught us that risk lies not simply in the product but in the rigor of our safety controls. 3-Methylbenzyl Chloride, like others in the benzyl chloride group, requires careful storage away from strong bases, oxidizers, and open flames. Our site adheres to strict safety standards—ventilated production lines, process containment, and personal protective gear are routine, not optional. We encourage every client to align their own protocols with these standards. Our technical support team regularly fields questions about safe transfer, ventilation, and emergency procedures. This isn’t box-ticking for us—it’s born from incident review meetings and practical factory experience.

    On large sites with significant output, investing in proper transfer pumps, sealed connections, and vapor scrubbing pays dividends in employee safety and air emission control. We make certain that our product containers leave our site in top condition, clean, sealed, and labeled in alignment with accepted chemical safety regulations.

    From Our Floor to Customer Success

    Feedback from real-world users shaped the way we fine-tune our product. Clients in batch chemical synthesis appreciate not only the purity but also the ease of measuring and mixing—we learned that avoiding excess residual solvents reduces foam and splashing in reaction initiation. In the field of materials science, customers demand traceability. Each lot leaves our production line with analytical documentation confirming the critical aspects: purity, residual solvents, and, where relevant, batch spectra.

    Discussion with users taught us that older packaging sometimes left residues or allowed air ingress. We responded by switching to newer drum linings and better seals, minimizing the loss of volatile content and keeping product stable even after months of storage. Routine engagement with logistics keeps our shipments reliable, avoiding delays that cause unpredictable schedules for customers.

    Supporting Advanced Applications

    Clients value direct answers. In synthesis of pharmaceutical intermediates, 3-Methylbenzyl Chloride appears as an essential alkylating agent. Thanks to its selectivity and manageable volatility, project teams find it easier to incorporate than more reactive halomethyl analogues. More than one client shared that a switch to our material reduced yield variability—an outcome that brings project savings as well as downstream reliability.

    For agrochemicals, formulators leverage our product’s controlled reactivity to introduce benzyl moieties into active molecules. Yields improve when starting materials are consistent, especially in multi-step syntheses, so we work to ensure our purity and packaging minimize exposure to moisture and light during transit.

    We have also seen steady growth in orders from specialty materials producers. In the creation of custom monomers and cross-linkers, 3-Methylbenzyl Chloride operates as a cornerstone. Its meta-methyl configuration diversifies polymer architectures, allowing clients to push product development in directions that simple benzyl chloride cannot match. In-house, our R&D works directly with customers’ technical leads, providing tailored analysis and process advice to keep projects on schedule and within expected yield ranges.

    Continuous Improvement: Leaning on Experience

    Every lot that leaves our facility carries the touch of our staff’s experience. Years of technical problem solving flow into the decisions we make about purification, storage, transportation, and customer engagement. New challenges constantly enter the market—a regulatory shift, a new export market, revised process specs for a key customer—and we respond by running pilot trials, re-checking analytical methods, and investing in small upgrades to keep both quality and safety at the highest standard possible.

    On more than one occasion, a partner working toward a regulatory filing required not only current data but a multi-year record of stability. We maintain archived documentation as a matter of best practice, supporting both repeat business and new regulatory submissions.

    Why Technical Dialogue Matters

    Sourcing specialty chemicals brings uncertainty, especially as environmental, safety, and product performance standards keep rising. Success hinges on daily conversation between production and customer—questions, feedback, real test data. We make it part of our approach to exchange insights openly, so if oddities appear during downstream reactions, we help troubleshoot and adapt. This exchange improves not just our own 3-Methylbenzyl Chloride; feedback loops improve our entire line of alkyl chlorides and related products.

    Over the last decade, process modifications have made handling safer, while our raw material controls improve consistency. Batch after batch, we stay focused on critical issues—moisture, color, residual toluene, chlorinated byproducts—each one reflecting adjustments made based on hands-on plant learning.

    End Use and the Future of Synthetic Chemistry

    Looking toward what comes next, our outlook remains practical: clients want stability in quality, reliability in delivery, and open lines for technical fixes. Whether 3-Methylbenzyl Chloride lands in a medicinal chemistry lab or a bulk manufacturing process, project managers and chemists alike look for partners with direct production know-how. That’s what keeps our own technical team engaged and motivates us to keep improving.

    New uses for 3-Methylbenzyl Chloride keep emerging as scientists investigate better ways to build molecules for energy storage, medical imaging, or next-generation coatings. Each request for unique packaging, tighter specifications, or technical clarification pushes us to innovate—by testing new purification steps, evaluating alternative raw material sources, even redesigning our production control system for stricter in-line monitoring.

    Our Commitment, Drawn from Daily Operations

    What sets direct manufacturers apart is more than access to the tank farm or on-site laboratories—it’s the unfiltered daily exposure to every aspect of production, shipment, and user experience. We have stood in the middle of night shifts and troubleshooting sessions, ensuring each lot not only meets specs but consistently supports customer deadlines and technical demands. 3-Methylbenzyl Chloride production, at its best, serves as a clear example of how specialty chemicals deserve serious stewardship.

    Feedback, traceability, and improvement drive our day-to-day work. Those approaching demanding syntheses or new formulation projects need not just a product, but a producer ready to listen, adapt, and push technical knowledge forward. Our approach remains straightforward: we anchor our work in real-world challenges, providing a reliable, responsive, and safe route to sourcing 3-Methylbenzyl Chloride no matter how the application evolves.