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HS Code |
786982 |
| Chemical Name | 3-Methoxy-2-Methylaniline |
| Cas Number | 57848-46-1 |
| Molecular Formula | C8H11NO |
| Molecular Weight | 137.18 g/mol |
| Appearance | Pale yellow to brown liquid |
| Boiling Point | 259-260 °C |
| Melting Point | N/A |
| Density | 1.07 g/cm3 |
| Solubility In Water | Slightly soluble |
| Flash Point | 111.7 °C |
| Refractive Index | 1.581 |
| Smiles | COc1cccc(N)c1C |
| Pubchem Cid | 5370599 |
| Synonyms | 2-Methyl-3-methoxyaniline |
As an accredited 3-Methoxy-2-Methylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 100-gram amber glass bottle with a screw cap, labeled with “3-Methoxy-2-Methylaniline,” hazard symbols, and handling instructions. |
| Shipping | **3-Methoxy-2-Methylaniline** is shipped in tightly sealed containers, protected from light, moisture, and incompatible materials. It is handled as a hazardous chemical, with proper labeling and documentation in accordance with local, national, and international transport regulations. Use appropriate protective equipment during handling and ensure ventilation during transfer and storage. |
| Storage | Store 3-Methoxy-2-Methylaniline in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of ignition. Keep it separate from strong oxidizers, acids, and bases. Protect from light and moisture. Label storage areas clearly and ensure proper chemical spill containment. Use appropriate chemical storage cabinets for flammable or toxic materials. |
Applications of 3-Methoxy-2-Methylaniline in Industrial Manufacturing3-Methoxy-2-Methylaniline serves as a specialty intermediate in several high-value industrial sectors. As a manufacturer, we supply this compound for tightly regulated production chains, each with advanced QA and compliance requirements. Below we describe the primary downstream markets where this raw material is directly integrated into core production processes. 1. Agrochemical Synthesis: Herbicide IntermediatesAgrochemical producers utilize 3-Methoxy-2-Methylaniline during multi-step syntheses of pyridine-based and aniline-derived herbicides. The material typically undergoes diazotization, followed by coupling or condensation routes with chloro-heterocycles or acid chlorides. End-users must verify trace amine content and control residual oxygenated by-products to conform to agrochemical purity specifications. QC processes require monitoring for fixed limits on residual solvents during formulation and pre-concentration. Final actives are typically formulated to field application standards after downstream salt-formation or formulation adjustments. Industry compliance standards
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2. Pharmaceutical Intermediate Manufacturing: Active Pharmaceutical Ingredient SynthesisPharmaceutical manufacturers employ this aromatic amine to build complex scaffolds for select API production, especially in the synthesis of small-molecule drugs containing methoxyphenyl or methylphenyl motifs. The compound undergoes N-alkylation, acylation, or further transformation as a stage intermediate. Reaction controls demand detailed documentation on impurity profiles, allergen status, and batch-to-batch consistency. Process validation involves scale-up from kilo-lab batches to industrial reactors with continuous monitoring for residual solvents and side-product minimization per ICH guidelines. Industry compliance standards
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3. Dye and Pigment Production: Manufacturing of Specialty ColorantsColorant engineers apply 3-Methoxy-2-Methylaniline as a diazo component in the synthesis of specialty azo dyes and oxidative pigments. The production process focuses on high-tint strength and controlled shade consistency, requiring precise adjustments in coupling conditions and reaction time. Downstream blending utilizes this intermediate for the production of temperature-stable and lightfast pigments intended for plastics and fiber coloration. Careful feedstock qualification, trace metal monitoring, and waste minimization procedures are enforced throughout large-scale operations. Industry compliance standards
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4. Specialty Polymer Additive Manufacturing: High-Performance Plastic ModifiersPolymer compounders integrate this aromatic amine as a reactive modifier or chain stopper in advanced engineering plastics and resins. The material’s functional groups enable targeted adjustment of thermal resistance and UV stability in the final polymer matrix. Process engineers monitor stability during co-polymerization with polyamides or polyesters, utilizing closed-feed loading and nitrogen-blanketed blending. Operators maintain strict traceability according to regulatory frameworks for food-contact or electronics-grade plastics. Industry compliance standards
Typical usage ratio
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Every day in our plant, 3-Methoxy-2-Methylaniline moves from heated reactors through glass-lined pipes. Its light brown sheen always signals the right conditions. We know it by sight, smell, and the way it behaves in the mix. The material's chemical arrangement—an aniline ring with methyl and methoxy groups—delivers precise reactivity. As manufacturers, consistency defines our reputation. If you ever walk across the factory floor, you can see the confidence that comes from years of producing this compound, from the raw materials to the final barrel. A batch that’s off-color or a slight difference in clarity signals a need to double-check ratios or tweak a heater. That hands-on knowledge steers production far better than paper specifications.
Years of working with 3-Methoxy-2-Methylaniline taught us that purity influences everything downstream. Each lot leaves our facility after rigorous GC and HPLC analysis, not just because that satisfies paperwork, but because impurities later affect end reactions—fouling catalysts, shifting hues in dyes, or altering pharmaceutical intermediates. The melting point might sound like a trivial number, but here it guides storage and shipping. Too much moisture in the storeroom and you see caking or even slow decomposition. So we keep it sealed in thick-walled drums, nitrogen-flushed, and test small sub-samples regularly instead of waiting for complaints. Every operator here takes those checks seriously.
In the world of amines, 3-Methoxy-2-Methylaniline occupies a stable, reliable spot. Its combination of methoxy (–OCH3) and methyl (–CH3) groups brings a balance of solubility and reactivity. As a raw material for organic synthesis, it often acts as a building block for advanced dyes—where color tone must not drift. A textile customer once described how even a subtle slip in our product’s spectrum rendered an entire barrel of pigment off-shade, costing them weeks of work. Our regular plant meetings discuss those downstream headaches, pushing us to watch for micro-variations by day, not just batch reports.
Besides colorants, the aniline core plays into agricultural chemicals. Its selectivity and functional group orientation open easier routes for clean pesticide intermediates, reducing unnecessary byproduct formation. Our process engineers work to stay ahead of the trend when regulatory controls shift—selecting routes using greener solvents and fewer hazardous reagents without upending reliability. Those process tweaks get reviewed frequently, balancing engineering costs against the practical constraints of keeping the product affordable and consistent for customers relying on continuous supply.
Anyone working with aniline derivatives sees subtle differences add up fast. 3-Methoxy-2-Methylaniline’s methoxy group at the 3-position delivers a milder electron-donating effect compared to straight 2-Methylaniline. That small difference means a safer handling profile, a less aggressive amine, and fewer runaway reactions in electrophilic substitution chemistry. We often compare it directly with 2-Methylaniline (o-Toluidine) and 3-Methoxyaniline when tuning intermediates for customers. Where standard methylated anilines can overreact, this one gives a welcome margin for error and remains more adaptable to variations in acid/base ratios.
The improved selectivity proves particularly useful in fine-chemical applications, especially in the custom synthesis circles where 'good enough' doesn’t cut it. We’ve worked closely with R&D teams from midsize pharma companies who’ve switched over after too many product returns caused by poorly controlled side reactions using other isomers. The methoxy functional group means the product dissolves better in polar solvents, scaling smoothly in continuous flow as well as batch operations—in each case, it takes fewer workups and offers reliable yields on multigram and multikilogram scales alike.
Unlike resellers or traders, manufacturing brings every challenge home. Batch-to-batch reproducibility defines our calendar. Every operator gets trained to watch for time lag in reaction completion. One slip—a little too much heat, a late quench—can trigger a cascade of rework steps. We run every change by the technical team, not just regulatory review. That culture of discipline and problem-solving persists, especially with temperature-sensitive intermediates like 3-Methoxy-2-Methylaniline.
A decade ago, our team invested in closed-loop nitrogen blanketing precisely to deal with the trace oxidation problems that can ruin color and limit shelf life. That one change brought down our reject rates. We learned that downstream blenders who receive wet or oxidized material can lose an entire day recalibrating their lines. Simple in-plant decisions pay dividends years down the supply chain.
On any given shift, we watch fixed and variable costs tick up if a reactor runs overtime, so the process must move cleanly—no nagging contaminant build-ups, no excess byproduct in the mother liquor. 3-Methoxy-2-Methylaniline comes out reliably pure, but only because we keep each unit op clean and prep raw materials right. Raw toluidine and anisole derivatives can vary from supplier to supplier; recognizing and correcting those subtle shifts in precursor purity remains a daily challenge, not a job for automated systems alone. We build shielded supply partnerships, negotiate directly with upstream extractors, and share analytic fingerprints both ways.
From an economic perspective, steady demand in electronic dye and agrochemical sectors shield this product from wild swings, but input volatility means we routinely review synthetic routes to stay ahead of margins. Reducing hazardous solvent use cuts cost and risk. Our in-house pilot facility lets us move from test tube to ton-scale in months, not years. Those cycles of review drive continuous improvement. Familiarity with the reaction’s quirks forged years of trust with downstream users—they know we care about blocking out-of-spec surprises.
Unlike traders, we see finished product through aging, transport, and every seasonal swing in the warehouse. One winter, a minor heating lapse led to premature crystallization—a lesson in logistics we won’t repeat. So now, all stock remains at stable temperature, monitored by on-site staff, not just sensors. Our own warehouse operators tell us every year that reliable container seals have saved entire lots from water uptake. Listening to these boots-on-the-ground reports trumps rigid protocols every time.
Another overlooked risk: the smell. Uncontrolled vapor, though not acutely toxic, brings regulatory scrutiny and neighbor complaints. Our continuous scrubbers and dual-layer seals stabilized air emissions years ago. No substitute for staff who care enough to log every unusual odor spike or drum bulge. We keep regular training updated, not because of compliance, but to protect everyone on-site and preserve reputation over decades, not quarters.
3-Methoxy-2-Methylaniline may show up as a line item in catalogs, but in practice, it’s a foundation for more advanced molecules. Downstream partners rely on this material’s fingerprint—UV/Vis spectra, trace metal content, water percentage. Every quality assurance round runs real analytical checks, not just checkbox paperwork. We’ve learned over the years that rushing a batch, or saving pennies on drying cycles, gets noticed fast once it hits a pilot plant or customer’s chromatography trace. Real consistency attracts the long-term customers who keep a plant running.
Product recalls or rejected loads have a heavy long-term cost, not only monetary but in trust. We invest in detailed retention samples, archiving data, and staying reachable for technical queries. Once, a client flagged a minor GC peak—the QA manager backtracked batch records, reviewed stored samples, and confirmed a shift in raw input that only our layered tracking would have revealed. That kind of integrity, built from direct accountability, doesn’t come from trading platforms or distribution deals. It’s the culture of transparent manufacturing.
Even after decades, we find ways to raise the bar. Last year, process engineers implemented new online analytics to spot impurities before they complete a batch. Small tweaks in reagent addition order improved throughput and further minimized waste. Switching to a safer, less volatile catalyst paid off not just in lower handling risk but in streamlining clean-up. Every change goes through a pilot run, stress-tested during actual production hours, not just on paper.
Environmental compliance warrants ongoing attention. Our wastewater plant handles amine-rich effluent; process changes lowered chemical oxygen demand (COD) output in the last two reporting cycles. Small process changes, like temperature control and slow drip addition rates, made the difference. The entire team—from engineers to the night-shift warehouse crew—engage every improvement cycle, with feedback at every stage.
The reach of 3-Methoxy-2-Methylaniline extends from academic labs to finished consumer goods. We’ve shipped to university research teams attempting new OLED materials and to large dye houses with legacy color formulas. Every application brings unique challenges. Custom blend requests arrive with detailed specs—sodium-free, halogen trace below detection, or dissolved only in pre-selected carrier solvents. Our technical team reviews these demands with our plant supervisors who know the line’s true capability.
Supporting new applications and responding to technical troubleshooting questions remains part of our daily commitment. Whether it’s an upstream extraction problem or an end-use issue with solubility or reactivity, our plant’s years of experience benefit everyone involved.
Having produced this chemical for years rather than sourcing it from shelves, our insights reflect practical experience—temperature swings, subtle purity shifts, impact on downstream users, and value in supporting R&D for evolving applications. Those details would go unnoticed unless you’ve handled the product across seasons, worked through supply chain snarls, and picked up the phone for late-night troubleshooting. We stake our reputation—and our livelihoods—on delivering 3-Methoxy-2-Methylaniline in line with real-world requirements, not generic promises. Each action, from bulk tank sampling to final drum inspection, channels a manufacturer’s connection to what customers truly experience.
For every kilogram shipped, we see a chain of trust in motion: laboratory chemists, production operators, logistics staff, and QC specialists, all working to keep 3-Methoxy-2-Methylaniline coming off the line as expected. Why does it matter? Lives and livelihoods depend on reliable products. Each lesson—whether a tweak in process or a hard-won procedure for drum storage—builds the foundation of trust that makes downstream innovation possible. This attention to detail, born from a manufacturer’s daily reality, stands behind every drum that leaves our site.