|
HS Code |
982491 |
| Chemical Name | 3-Iodo-4-Methoxyaniline |
| Cas Number | 31721-50-9 |
| Molecular Formula | C7H8INO |
| Molecular Weight | 249.05 g/mol |
| Appearance | Light brown to brown solid |
| Melting Point | 61-65°C |
| Purity | Typically ≥98% |
| Solubility | Slightly soluble in water, soluble in organic solvents |
| Smiles | COC1=C(C=C(C=C1)N)I |
| Inchi | InChI=1S/C7H8INO/c1-10-7-3-2-5(9)4-6(7)8/h2-4H,9H2,1H3 |
| Storage Temperature | Store at 2-8°C |
| Mdl Number | MFCD06745667 |
As an accredited 3-Iodo-4-Methoxyaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 25-gram amber glass bottle with a secure screw cap, labeled "3-Iodo-4-Methoxyaniline" and safety/hazard information clearly displayed. |
| Shipping | 3-Iodo-4-Methoxyaniline is shipped in tightly sealed, chemical-resistant containers to prevent contamination and degradation. The package includes hazard labeling per relevant regulations and is handled as a potentially harmful substance. It is transported under controlled conditions, avoiding extreme temperatures, and compliant with safety and hazardous material shipping guidelines. |
| Storage | 3-Iodo-4-Methoxyaniline should be stored in a tightly sealed container, away from light, moisture, and incompatible substances such as strong oxidizing agents. Keep in a cool, dry, well-ventilated area, ideally in a desiccator. Properly label the container and store at room temperature or as specified by the manufacturer. Use appropriate personal protective equipment when handling. |
Applications of 3-Iodo-4-Methoxyaniline in Industrial Manufacturing3-Iodo-4-Methoxyaniline acts as a specialized intermediate for advanced chemical synthesis. As a dedicated manufacturer, we supply this compound to key sectors where precise structure and purity are essential for downstream transformation. Below we present the principal industrial application scenarios, covering compliance, dosage, processing steps, and resulting end products. 1. Pharmaceutical API Intermediate SynthesisPharmaceutical manufacturers incorporate this material as a building block during multi-step synthesis of specific active pharmaceutical ingredients. Its presence enables regiospecific introduction of iodo and methoxy groups on aromatic rings, critical for biologically targeted drugs, especially kinase inhibitors and CNS-active agents. Our standard supports strict traceability and reactivity control required by leading formulation laboratories. Industry compliance standards
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2. Agrochemical Active Ingredient SynthesisFine chemicals producers employ this raw material to create specific fungicidal and herbicidal agents. The controlled introduction of iodo and methoxy substituents influences target selectivity and environmental degradation rate in field-applied formulations. Our material meets required purity thresholds to avoid downstream phytotoxicity or regulatory non-compliance. Industry compliance standards
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3. Dye and Pigment Intermediate ProductionSpecialty pigment and dye manufacturers utilize 3-Iodo-4-Methoxyaniline in azo coupling, sulfur dye synthesis, and development of high-stability colorants for textile and plastic processing. The functional groups impart unique chromophoric shifts and molecular stability, serving applications where high-color fastness is crucial. Industry compliance standards
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4. Electronic Chemical Synthesis (OLED and Advanced Material Precursors)Producers of organic electronic materials integrate this compound into tracks for OLED emitter layer synthesis and advanced functional coatings. The electron-donating methoxy group and halogen content enable precise adjustment of energy band structure in downstream organic semiconductors, critical to optoelectronic device performance. Industry compliance standards
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5. Specialty Chemical R&D: Molecular Probe and Label SynthesisContract research organizations and analytical reagent firms leverage this compound to synthesize molecular probes and bioconjugation labels for imaging and diagnostic applications. Its substitution pattern supports site-specific tagging with radiolabels or fluorophores, demanded by precise structure–activity studies and sensitive detection kits. Industry compliance standards
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From the start, producing 3-Iodo-4-Methoxyaniline has challenged us to uphold both quality and traceability. As a specialized chemical, this compound—known by its CAS number 22907-55-9—brings precision to the field of fine chemical manufacturing. Unlike materials churned out by intermediaries who cannot vouch for the origin of their stock, we walk every step from raw iodine selection to final quality inspection. Each batch leaving our facilities reflects the persistent care practiced by teams who respect the science and the safety tied to the molecule. This respect only grows when considering its wide-ranging roles in synthesis, especially for pharmaceutical intermediates and dye research.
Consistency forms the backbone of our manufacturing process. Every flask, every filtration step, and every drying cycle follows procedures honed by years of direct hands-on experience. The typical purity for our 3-Iodo-4-Methoxyaniline exceeds 98%, supported by HPLC and NMR test results. Trace metal analysis, moisture testing, and careful visual inspection occur before packing. Our chemists maintain strict attention to impurities—the types that seem minor on paper, yet can disrupt downstream chemistry or bioactivity. Each crystalline lot is logged with test data and batch numbers, providing clear routes for traceability and regulatory compliance. Instead of relying on third-party assurances, our in-house lab takes responsibility for every analytic result listed.
The reach of 3-Iodo-4-Methoxyaniline extends to those who synthesize complex molecules for medicinal, agricultural, or pigment applications. Over several years of serving custom synthesis clients, we've observed demand grow among R&D teams exploring iodine-driven transformations. The methoxy group paired with the iodo position on the benzene ring gives this compound both selectivity and reactivity in forming C-N, C-O, or cross-coupling bonds—making it attractive for Suzuki, Sonogashira, or Buchwald–Hartwig strategies. Medicinal chemists recognize the unique electronic and steric attributes conferred by this substitution, streamlining the synthesis of certain antitumor, antiviral, and CNS compounds. In more specialized dye formation work, this aniline derivative stands out for its handling of electron-rich and electron-deficient zones, expanding the palette for functional chromophores. Our own technical team continues to interface with researchers to address solubility, reaction yields, and potential impurities that might hinder the purity of their target molecules.
Not all compounds marketed under this name deliver the same level of performance in real-world settings. As the original producer, we field customer samples from nearly every major geochemical region. Fundamental differences arise from small choices: the grade of starting iodine, the reliability of amination steps, and the rigor of post-reaction filtration. More than once, chemists in need of true batch-to-batch consistency have shown us competitive samples. We've seen variations in hue, inconsistent crystallinity, or residual halides—all of which can slow down an otherwise robust process. Our synthesis prioritizes clarity in color, reproducibility in melting point, and low residual inorganic salts. This focus reflects years of learning what actually moves lab-scale discoveries to scalable, viable routes. Our batch records and in-house methods line up with customer-driven audits and feedback, rather than marketing claims that can't be substantiated in routine operations.
Scaling up the production of 3-Iodo-4-Methoxyaniline highlights many truths about chemical manufacturing. Small-lot synthesis, common among laboratory traders or non-integrated workshops, rarely addresses the needs of process chemists who see initial success but then confront bottlenecks. Our operation grew with the demands of both kilo-scale orders and mid-scale pilot programs, letting us develop in-line purification systems, bulk drying setups, and supply chains that remain responsive to spikes in global demand. Instead of improvising with stop-gap approaches or outsourcing stages, we assemble raw material sourcing, process chemistry, solvent recovery, and packaging under one roof. This coordinated approach matches our actual production with customer projections while reinforcing promises made during initial consultation stages.
Much of the market's shortfalls trace back to haphazard storage or transport practices. Air and moisture negatively affect sensitive iodoanilines, introducing risks for darkening or skip reactions. Our site maintains low-humidity climate control, and staff receives constant training on handling actual product, not just theoretical guidelines. In practice, material kept in tight, sealed containers and nitrogen-blanketed vessels holds up without yellowing or caking. Documented shipping protocols further restrict fluctuations in transit conditions, so labs receive the material in the same quality it held at the time of packing. Both new and repeat clients connect our consistency in physical handling with higher downstream confidence—not just for compliance, but for actual results on their end.
As the world tightens compliance requirements for specialty chemicals, manufacturers like us shoulder greater diligence in documenting and authenticating origins. 3-Iodo-4-Methoxyaniline, due to its relevance in regulated sectors, calls for direct oversight rather than reliance on third parties. Our records include raw source documentation and all intermediates tested for compliance. Each product’s lifecycle, from iodine purchase to certificate of analysis, passes regulatory checks expected in the markets we serve. This includes export documentation and compatibility with reach, TSCA, and other frameworks where applicable. Our technical and compliance teams stay updated on regulatory changes, adjusting internal procedures the same moment standards shift globally.
We differentiate 3-Iodo-4-Methoxyaniline not only from generically similar iodoanilines but from every other meta- and para-substituted aniline variant that ends up on the chemist’s bench. A similar-looking compound—one bearing a bromine or a methyl group instead of iodine or methoxy—performs differently in both cross-coupling efficiency and biological applications. Over time, our R&D and customer feedback revealed that the iodo-and-methoxy pairing improves yields in Sonogashira and Suzuki reactions compared to plain iodoanilines or their bromo counterparts. Reaction rates accelerate, and side products drop measurably. In the context of medical chemistry or pigment design, these changes reveal themselves not through theoretical studies but through submitted product samples, successful clinical candidates, or brighter chromophores in finished goods. An authentic batch made directly at the source skips the cascading problems seen in resold intermediates that lack strong documentation.
As professional manufacturers, we know that chemical innovation and environmental consciousness intersect in daily routines. Dealing with iodoanilines brings unique risks: used solvents, excess halides, and energetically loaded intermediates. Over a decade’s worth of plant operation, we've invested in solvent recovery systems that channel over 80% of process solvents for direct re-use, slashing the environmental toll and input costs. All waste iodides undergo staged neutralization and safe disposal or reclamation. We treat both product and byproduct as streams affecting both workplace safety and community relations, not simply compliance box-ticking. Real-world experience processing multi-ton volumes makes our approach to hazard minimization informed not by formulas but by lessons learned on real equipment, by familiar hands.
Customers’ priorities have taught us that timely answers about availability and shipping windows hold as much weight as purity metrics. Not every order is routine: customized packing, rush requests, multi-modal delivery—each demand direct, unfiltered communication with real staff at the production site. As direct producers, we bridge R&D intent with manufacturing constraints, giving usable feedback on scheduling, lead times, and batch production limits. Rather than passing questions onto anonymous suppliers, our chemists, account handlers, and shipping coordinators keep exchanges direct and grounded in our own day-to-day realities. These conversations shape improvements in product quality and customer service, feeding back into every run we produce.
Producing specialty chemicals like 3-Iodo-4-Methoxyaniline involves a basket of unavoidable risks—from volatile feedstock prices to changing demand cycles in specialty chemicals and pharmaceutical intermediates. Over many years of operation, we’ve learned that contingency stocks, genuine raw material partnerships, and in-house process control weather these storms better than spotmarket buys or last-minute import windows. Our staff's experience with production-scale chemistry, regulatory filings, and logistics means we catch emerging supply chain issues well before they morph into actual shortages or unplanned downtime. By standing behind our own QC and supply chain logic, we cut through much of the noise and uncertainty that tangles third-party merchants. Practical adaptation—whether it means shifting batch sizes, reserving capacity for strategic partners, or rapid certification for entering new regulatory zones—comes not from generic procedure but from accumulated practice.
Years of practice as a manufacturer place us in regular contact with end users—process chemists, R&D managers, quality controllers—from every corner of the globe. Each interaction, whether it involves challenging a protocol, troubleshooting a yield issue, or dissecting an impurity profile, adds layers to our technical base. 3-Iodo-4-Methoxyaniline’s performance is validated not only by our test data but by hundreds of project reports, collaborative problem-solving sessions, and even failures that pointed the way toward better handling or synthesis methods. Feedback flows back into our workflow, and we regularly invite client audits, process walkthroughs, and open conversations about improvement points. These exchanges—grounded in real-world usage and consistently reinforced with new data—help ensure our product evolves along with advances in application science.
Manufacturing 3-Iodo-4-Methoxyaniline comes with rewards and challenges shaped by global shifts in research, regulation, and end-use diversity. As research into new functional molecules expands, so does interest in highly pure, well-documented starting materials. Our efforts now reach beyond commodity sales, pushing toward collaborative partnerships where secure supply chains, shared technical data, and mutually defined standards matter most. We make ongoing investments in training, analytical methods, and better environmental controls not just to tick off compliance boxes but to assure those who trust us that their own standards can be met or exceeded. Commitment to transparency, technical rigor, and the daily realities of chemical processing remain the foundation for every synthesis and every shipment of 3-Iodo-4-Methoxyaniline that passes from our team into global hands.
Operating as a direct manufacturer of 3-Iodo-4-Methoxyaniline offers visibility, reliability, and access impossible to match through indirect channels. Clients relying on this specialty grade for research or production encounter fewer surprises and more verifiable results because each stage—from initial synthesis to final QA—remains under our active, ongoing supervision. Through years of practical service, technical feedback, and process optimization, we strive to embody the values and standards expected by those for whom every milligram counts, every impurity matters, and every shipment impacts a wider process. In this way, our role as a true producer goes beyond simply offering a product; it anchors the success of those who depend on consistent, high-performance intermediates to drive their own discoveries forward.