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3-Hydroxy-3-Methyl-2-Butanone

    • Product Name 3-Hydroxy-3-Methyl-2-Butanone
    • Alias Acetoin
    • Einecs 202-315-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    766539

    Iupac Name 3-Hydroxy-3-methylbutan-2-one
    Common Name Acetoin
    Cas Number 513-86-0
    Molecular Formula C4H8O2
    Molar Mass 88.11 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Pleasant buttery odor
    Melting Point -2 °C
    Boiling Point 148 °C
    Density 0.992 g/cm3
    Solubility In Water Miscible
    Flash Point 49 °C
    Refractive Index 1.424
    Pubchem Cid 179
    Smiles CC(=O)C(C)(O)C

    As an accredited 3-Hydroxy-3-Methyl-2-Butanone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 500g bottle of 3-Hydroxy-3-Methyl-2-Butanone comes in a tightly sealed amber glass container with a hazard label.
    Shipping 3-Hydroxy-3-Methyl-2-Butanone is shipped in tightly sealed containers, protected from moisture and extreme temperatures. It should be handled in accordance with safety regulations for flammable liquids. Ensure proper labeling and documentation, and comply with local and international shipping standards for hazardous chemicals to prevent leaks and potential health hazards.
    Storage 3-Hydroxy-3-methyl-2-butanone should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizers and acids. Keep away from direct sunlight and moisture. Ensure proper labeling and access for only trained personnel, and follow all relevant safety and regulatory guidelines during storage.
    Application of 3-Hydroxy-3-Methyl-2-Butanone

    Applications of 3-Hydroxy-3-Methyl-2-Butanone in Industrial Manufacturing

    3-Hydroxy-3-Methyl-2-Butanone, also known as diacetone alcohol, serves as a functional intermediate and specialty solvent across multiple industrial fields. Our manufacturing controls cover purity, consistency, and traceability, meeting the stringent criteria required for integration into regulated downstream products. Below we outline the proven applications and relevant parameters used by clients in their specific industries.

    1. Coatings and Paints Solvent Formulations

    In the coatings sector, formulators leverage this ketone alcohol as a slow-evaporating coalescent and viscosity modifier, supporting both solvent-based and waterborne systems. It stabilizes dispersions, improves flow characteristics, and prevents pigment flooding in the final mix. Blends must consider local VOC legislation and compatibility with binder technologies to ensure regulatory compliance and performance in the end application.

    Industry compliance standards

    • European REACH Regulation (EC) No 1907/2006
    • US EPA 40 CFR Part 59 (National Volatile Organic Compound Emission Standards)
    • SCAQMD Rule 1113 Architectural Coatings
    • OSHA Hazard Communication Standard 1910.1200

    Typical usage ratio

    • 2–10% by weight in solvent blends for industrial coatings
    • Adjustments depend on system solids, resin type, and target evaporation rate

    Downstream process integration

    • Added during the grind or let-down stages of coating production
    • Integrated before final filtration and can be used as a post-additive for viscosity tuning

    Final product types

    • Industrial metal primers
    • Waterborne wood finishes
    • Automotive refinish paints
    • Protective maintenance coatings

    2. Chemical Intermediate for Pharmaceutical Synthesis

    Chemists in API manufacturing employ this compound as a building block for custom syntheses, especially in creating substituted diols and as a protective group or solvent in Grignard and reduction reactions. Its low toxicity profile and reactivity enable compliance with international pharmacopeial guidelines in controlled synthesis environments.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP–NF, EP, JP monographs (process chemical conformity)
    • FDA 21 CFR part 211 (cGMP for finished pharmaceuticals)
    • EU GMP Annex 8 (sampling and testing intermediary chemicals)

    Typical usage ratio

    • 5–25 mol% relative to limiting reactant, depending on step specificity
    • Ratios adjusted by reaction yield targets and residue minimization requirements

    Downstream process integration

    • Charged into reactor during intermediate step
    • Often serves as both reagent and process solvent in multi-step synthetic routes

    Final product types

    • Pharmaceutical intermediates
    • Chiral alcohol derivatives
    • Active pharmaceutical ingredients (e.g., antihistamines, cardiovascular agents)
    • Specialty fine chemicals for R&D

    3. Solvent and Additive in Industrial Cleaning Agents

    Manufacturers of heavy-duty degreasers and precision cleaners use this alcohol for its strong solvency towards oils, waxes, and resins, enabling high soil removal with moderate evaporation. Its chemical stability and low tendency to form peroxides support extended shelf life and consistent batch reproducibility. Special attention is paid to worker exposure and residual limits during formulating and application.

    Industry compliance standards

    • OECD Guidelines for Testing of Chemicals (biodegradability and toxicity)
    • US EPA Safer Choice Program
    • REACH Annex XVII restrictions (worker safety labeling)
    • ANSI/AAMI ST79 for medical device cleaning where applicable

    Typical usage ratio

    • 3–20% mass concentration in formulated cleaning mixtures
    • Higher use for industrial equipment cleaning; lower for surface wiping

    Downstream process integration

    • Blended into surfactant or solvent bases during mixing stage
    • Compatible with aqueous and semi-aqueous carrier fluids

    Final product types

    • Metalworking fluids
    • Electronic component cleaners
    • Industrial facility degreasers
    • Precision instrument washing agents

    4. Resin Manufacturing and Modification

    Resin producers utilize this ketone alcohol as a chain stopper, cross-linking agent, or reactive solvent in alkyd, polyester, and acrylic resin synthesis. Its tertiary alcohol structure promotes flexibility in polymer backbones and fine-tunes molecular weight without introducing excessive branching. QC laboratories monitor residuals to guarantee compliance for downstream applications in coatings, adhesives, and plastics.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • Directive 2011/65/EU RoHS (for electronics-polymer use)
    • ASTM D1259 / D2587 (Testing of Resin Systems)
    • EN 71-3 Toy Safety (when used in toy coatings and adhesives)

    Typical usage ratio

    • 1–8% of total monomer/reactant charge during reaction
    • Exact values depend on required degree of polymerization and performance target

    Downstream process integration

    • Introduced as a functional monomer during bulk or solution polymerization
    • Serves both as a chemical modifier and a processing aid

    Final product types

    • Industrial alkyd resins
    • Waterborne acrylics for coatings
    • Polyester resins for fiberglass composites
    • Reactive hotmelt adhesives

    5. Ink and Printing Chemical Solvent Applications

    Producers of flexographic and gravure inks select this compound for its balance of drying rate and leveling. It enhances pigment wetting in aqueous and solvent-based inks, supporting consistent print density on various substrates. Technical teams manage residual solvent levels to comply with environmental and worker safety standards, considering local emissions and global export requirements.

    Industry compliance standards

    • EN 71-9 (Safety of Toys - Organic Chemical Compounds)
    • Swiss Ordinance on Materials and Articles in Contact with Food (SR 817.023.21)
    • US FDA 21 CFR 175.105 (Adhesives in contact with food packaging)
    • US EPA Clean Air Act, Section 112 (Emissions control)

    Typical usage ratio

    • 2–6% by volume in ink concentrate formulations
    • Proportion depends on substrate absorption, press speed, and jet print specifications

    Downstream process integration

    • Added during pigment dispersion or as a post-blend viscosity regulator
    • Used in ink concentrate and ready-to-use blends

    Final product types

    • Flexographic packaging inks
    • Gravure printable films
    • Digital inkjet fluids for commercial printing
    • Specialty printing pastes for textiles

    6. Flavor and Fragrance Intermediate Synthesis

    Specialty manufacturers synthesize aroma chemicals and flavoring agents by incorporating this alcohol as a selective condensation and aldol reaction intermediate. Its mild odor profile and clean conversion minimize off-notes in downstream isolates, with control protocols to ensure food-grade or IFRA-compatible status, depending on the final market.

    Industry compliance standards

    • FEMA GRAS (Flavor and Extract Manufacturers Association - Generally Recognized as Safe)
    • IFRA Code of Practice (for fragrance applications)
    • EU Regulation (EC) No 1334/2008 (flavouring substances)
    • US FDA 21 CFR 172.515 (Synthetic flavoring substances and adjuvants)

    Typical usage ratio

    • 0.1–5.0% by weight of batch, depending on flavor/fragrance pathway and target concentration
    • Lower ratios for highly potent aroma chemicals

    Downstream process integration

    • Charged during key synthetic steps as a condensation partner or precursor
    • Subject to in-process purity monitoring and downstream distillation

    Final product types

    • Fruit and berry ester concentrate bases
    • Green note aroma chemicals
    • Natural-identical flavorings for beverage applications
    • Solvents for fragrance encapsulation matrices
    Free Quote

    Competitive 3-Hydroxy-3-Methyl-2-Butanone prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

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    Certification & Compliance
    More Introduction

    3-Hydroxy-3-Methyl-2-Butanone: A Closer Look at Our High Purity Product

    Every batch of 3-Hydroxy-3-Methyl-2-Butanone that leaves our facility is the result of deliberate, hands-on process management and extensive expertise. We have dedicated years to developing this specialty compound for refined industries. Having produced it at scale for a variety of applications, we understand the role it plays in organic synthesis, fragrance creation, and pharmaceutical development. Our production lines prioritize consistency, purity, and traceability, which matter much more than surface-level purity claims seen elsewhere. The market often only whispers about these behind the label, but our work doesn’t end at the spec sheet.

    Model and Specifications that Reflect Real-World Needs

    Across years of operation, we found most buyers search for a model that meets exact purity needs. Our 3-Hydroxy-3-Methyl-2-Butanone typically achieves a minimum purity of 99%, determined by independent testing as well as our in-house chromatographic analysis. The compound, stable under ambient conditions in a sealed drum, arrives clear and nearly colorless—each feature directly tied to the input materials, purification steps, and handling practices at the plant.

    Specifications don’t just reflect numbers on a lab report. They mirror daily process discipline—a batch’s water content can reach sub-0.2%, and residual volatiles rarely creep above safe limits. We manage each kinetic step carefully, so the product maintains low impurity levels even at scale, with physical inspection at each transfer point. There’s no substitute for firsthand filtration and vacuum transfer experience, and in our view, this defines genuine quality assurance.

    Direct Applications Supported by Real-World Feedback

    Purchasers of our 3-Hydroxy-3-Methyl-2-Butanone work in fine chemicals, flavors and fragrances, and pharmaceutical intermediates. A good portion goes into the creation of flavors where control of side-products makes or breaks downstream formulations. Over the years, the same flavor houses keep returning, as predictable purity helps avoid costly inconsistencies in finished products.

    Pharmaceutical companies demand certainty in precursor synthesis, trusting us for our transparent process records and batch repeatability rather than flashy marketing. The compound serves as an intermediate where uncontrolled impurities could compromise safety studies. With each lot traceable to raw material source and reactor parameters, we offer that certainty without shortcuts.

    Some of our frequent buyers formulate specialty resins and coatings, finding that the low water and aldehyde content minimizes yellowing, improves reaction conversion, and reduces waste. No marketing claim replaces the daily grind of meeting those process requirements for every shipment.

    Differences That Influence Performance and Customer Trust

    Making 3-Hydroxy-3-Methyl-2-Butanone isn’t a uniform process across producers. Experience in the industry brings respect for these differences. We never approach this as a commodity; every small variation in quality shifts outcomes for end-users.

    Some companies focus on yield and throughput, producing a technical grade compound where trace contaminants easily pass through. These products may seem suitable for less demanding applications. Years of customer feedback taught us that even small differences in isomer content and trace volatiles can cause downstream disruptions. That became clear as we collaborated with multinational fragrance and pharma companies facing batch-to-batch headaches traced to unseen impurities.

    Competitive products may meet stated purity, but overlook color stability or product shelf life. We address these issues through continuous monitoring, tight packaging controls, and by integrating lessons from every quality deviation we've encountered. Seeing how easily off-odors creep into storage tanks, we've adopted better blanketing systems and regular drum inspections—not practices found in every plant.

    Product flow and consistency also come from packaging expertise. During hot summer months, tanker temperatures soar. We have adjusted our filling and shipment cycles so product does not degrade during transit or storage, evident from customer QC audits. Repeated calls and after-sales discussions led to the adoption of thicker, lined drums that shield the product from atmospheric moisture, an adjustment only manufacturers committed to long-term supply can justify.

    While some competitors prioritize lowest-cost output, our team aims for reliability and actionable feedback. Our traceability goes beyond required paperwork; we link batches to reactor logs dating back over a decade, making root cause analysis possible whenever a question arises. This has prevented more than a few production hiccups down the supply chain for our partners.

    Quality: Not a Tagline, But a Daily Process

    Products like 3-Hydroxy-3-Methyl-2-Butanone function as critical components for finished goods. Our process decisions seek to minimize the chemical noise that confounds analytical work and hurts batch yields for our buyers. Each stage—from hydrogenation to fractionation—brings its opportunities for drift or contamination, which we actively manage with hands-on testing. All of this matters little on a glossy website, but shows up fast during real-world use.

    In one recent example, a customer manufacturing a new active pharmaceutical ingredient discovered inconsistencies from a previous supplier. The issue traced back to micro-impurity levels—something that typically escapes broad QC checks. Our willingness to run additional impurity screens on new lots helped save their project timeline. These aren’t stories often found in marketing copy, yet they form the unspoken backbone of genuine supply partnerships.

    We never rely on batch spot checks alone. Each month, teams meet on the production floor to review outlier data and tweak parameters based on aggregated outcomes, not just individual test reports. Our lab staff see first-hand how process conditions change results, leading to practical improvements in sampling, transfer, or purification. Insights gathered from these routines help us set specification limits anchored in daily reality, not just industry standards.

    Environmental Practices Guided by Experience

    Regulation and sustainability shape the way chemicals get produced, whether or not a buyer asks about it directly. Lived experience in this industry revealed that corners cut today easily become tomorrow’s headaches. Our plant has adopted solvent recovery and vapor recycling systems designed after multiple rounds of practical experimentation. We filter and treat process effluents in real time, reducing waste at the source. Teams monitor emission levels—not simply because it’s required—but because every ton of solvent recycled means both better economics and a lighter footprint.

    Decisions about bulk handling and intermediate storage now reflect years of watching what works and what leads to leaks or over-exposures. Tasks that appear simple, like drum rinsing or valve cycling, receive strict protocols and real-world training. Many of these tweaks arose from operational setbacks and candid staff feedback. Guidelines written from top-down management rarely deliver as much stability as routines forged in the trenches by experienced workers. The result is a safer product, produced in a way that supports both longevity and compliance for staff and downstream partners.

    Meeting Shifting Industry Demands

    Market demand for 3-Hydroxy-3-Methyl-2-Butanone rarely moves in straight lines. Shifts in global shipping routes, raw material costs, and end-market regulation all force regular re-evaluation. Our approach adapts out of necessity; we never treat our process as static. This isn’t always about profit pressures. When COVID-19 disrupted global supply chains, we encountered a surge in requests from pharmaceutical customers seeking reliable alternatives. Timely response required flexible scheduling, overtime production, and close cooperation with raw material vendors. Instead of delaying orders, our teams coordinated with buyers to forecast needs and schedule shipment slots. The trust built during that period now informs much of our ongoing operational priority.

    Few appreciate the tightrope act required to balance capacity expansion against the background noise of price volatility and shifting demand. Additional reactors or storage tanks demand significant investment. We have weighed these decisions by studying not just current order books but also repeated customer conversations. When buyers provide specific feedback on delivery, shelf life, or performance, we log these outcomes and work the findings directly into process revisions. The hands-on manufacturer always listens to users at the end of the chain, because their success keeps the larger machine running.

    Supporting Research and Development

    Researchers and formulators face increasing pressure to speed up product launches and optimize process economics. We view part of our job as supporting their experiments, from pilot scale to commercial rollouts. Over the past year, our technical team supplied over a dozen R&D groups with product samples and handled non-standard shipping requirements for urgent testing. These collaborations gave us a window into changing guidelines for impurities, packaging, and documentation. Our production runs for R&D batches use the same controls as full-scale lots, which allows for smoother scale-up and fewer process surprises.

    Real innovation doesn’t happen in isolation. A global flavor company once asked us to modify product storage conditions after seeing unexpected shifts in aroma profile. We ran side-by-side stability studies under their stipulated conditions, updated our packaging protocols, and eliminated the issue in subsequent lots. Our best product improvements continue to come from these back-and-forth exchanges with users at the bench and on the factory floor.

    Packaging and Logistics Rooted in Worker Know-How

    Transport and storage of 3-Hydroxy-3-Methyl-2-Butanone present a host of practical challenges. Each step—drumming, tanking, loading, or unloading—carries its own risks that formulas and specs can't predict. Our logistics staff have spent years adapting workflows to changing seasons, load sizes, and customer needs. We track lot numbers by drum and train handling teams to recognize early signs of leaks, temperature swelling, or cross-contamination.

    Packaging choices—such as double-sealed drums and moisture barrier liners—result from real headaches with shipping loss and aging product, not just theory. International buyers increasingly request full documentation on packaging compatibility, so we provide the full chain of custody for each shipment. We back up every decision with field-tested experience rather than abstract claims about safety.

    Unlike traders or resellers, we hold responsibility for every return, spillage, or delay. Our operations team always follows up personally on transport incidents, even years after the initial shipment. This hard-earned trust remains the foundation of long-term customer relationships, outlasting price moves and product cycles.

    Continuous Improvement: Lessons from the Shop Floor

    No process stays perfect, and the lessons often come from unheralded workers on the ground. We maintain open communication channels for production staff, chemists, and shippers to report problems and suggest tweaks. Many advancements in product purity, packaging, or logistics grew from these frontline observations.

    After seeing how micro-leaks during filling damaged a batch two summers ago, our team overhauled seals and introduced enhanced bulk transfer lines. Follow-up testing showed a marked decrease in contaminant ingress. These changes rippled out to benefit every customer, even those unaware of the initial hiccup. The feedback loop between plant operations and customer support forms the backbone of resilient manufacturing, giving a practical focus that can’t be boxed into a catalogue spec.

    Customer Support Runs on Experience—not Promises

    Most issues in chemical supply arise long after a contract is signed. Our support staff draws directly on daily manufacturing knowledge to troubleshoot user concerns. If a customer struggles with storage questions or unusual product behavior, we send technical staff with plant floor experience, not just manuals, to identify and solve the problem.

    For longstanding partners, we often adjust delivery schedules or packaging size in response to changing inventory cycles. Personal relationships with customers let us identify brewing issues before they turn critical. In multiple cases, early warning from our ex-operators saved both parties from costly project delays or losses in high-value batches.

    Ethical Manufacturing and Long-Term Partnerships

    The chemical industry earns its reputation through lived experience, not marketing. As one of the original producers with decades invested in this process, we advocate for standards based on rigorous monitoring, factual reporting, and open collaboration with both customers and regulators. We avoid shortcuts that trade short-term profit for long-term risk, standing by every product that leaves our plant.

    Our footprint in 3-Hydroxy-3-Methyl-2-Butanone comes not just from installed capacity, but from lessons learned, failures adjusted, and ongoing dialogue with an evolving customer base. The goal—stronger applications, fewer disruptions, and reliable outcomes—gets built batch by batch, with every operator, chemist, and shipper sharing responsibility.

    Summary: Experience Built into Every Drum

    Buyers seeking 3-Hydroxy-3-Methyl-2-Butanone weigh many variables that data sheets can't capture. Choosing a hands-on manufacturer means tapping into a system where product history, process fine-tuning, and hard-won expertise converge. Every lot leaving our lines reflects this collective dedication, shaped by open exchange, real-world adaptation, and a genuine commitment to supporting industries that power daily life. For us, producing this compound is not just a process, but a continual investment in reliability, safety, and customer trust.