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3-Hydroxy-2-Methyl-4H-Pyran-4-One

    • Product Name 3-Hydroxy-2-Methyl-4H-Pyran-4-One
    • Alias Maltol
    • Einecs 212-673-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    812140

    Chemicalname 3-Hydroxy-2-Methyl-4H-Pyran-4-One
    Molecularformula C6H6O3
    Molecularweight 126.11 g/mol
    Casnumber 496-72-0
    Appearance Yellow to yellow-brown crystalline powder
    Meltingpoint 142-146 °C
    Boilingpoint 359.1 °C at 760 mmHg
    Solubility Soluble in water, ethanol, and methanol
    Density 1.294 g/cm³
    Pka 7.08
    Smiles CC1=COC(=O)C(O)=C1
    Pubchemcid 985
    Iupacname 3-hydroxy-2-methyl-4H-pyran-4-one
    Refractiveindex 1.536

    As an accredited 3-Hydroxy-2-Methyl-4H-Pyran-4-One factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of 3-Hydroxy-2-Methyl-4H-Pyran-4-One, sealed with screw cap and labeled with safety information.
    Shipping **Shipping Description:** 3-Hydroxy-2-Methyl-4H-Pyran-4-One should be shipped in tightly sealed containers, protected from moisture and light. It is typically transported at ambient temperature as a stable, low-hazard substance. Ensure compliance with local and international chemical transportation regulations. Appropriate labeling and safety data sheets (SDS) must accompany the shipment.
    Storage 3-Hydroxy-2-methyl-4H-pyran-4-one should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from direct sunlight and sources of ignition. Keep it away from incompatible substances such as strong oxidizing agents. Ensure storage is in accordance with local regulations and label the container clearly. Use appropriate personal protective equipment when handling.
    Application of 3-Hydroxy-2-Methyl-4H-Pyran-4-One

    Applications of 3-Hydroxy-2-Methyl-4H-Pyran-4-One in Industrial Manufacturing

    3-Hydroxy-2-methyl-4H-pyran-4-one is a specialty intermediate widely used in high-value sectors such as flavor and fragrance compounding, pharmaceutical APIs, fine chemicals, and food additive manufacturing. As the original manufacturer, we support leading companies in each sector with consistent quality, tailored grades, and full documentation support for regulated applications.

    1. Flavor and Fragrance Compounding

    This molecule serves as the core building block for the Maillard-type aroma ingredient known as maltol. It contributes caramellic, bready, and fruity notes in complex food flavor formulations, as well as in tobacco, beverage, and confectionery fragrances. Blenders rely on this intermediate to craft stable, high-impact flavor profiles while meeting evolving purity and residue requirements essential for commercial scale-up.

    Industry compliance standards

    • FCC (Food Chemicals Codex) for maltol derivatives
    • IFRA guidelines on fragrance raw materials
    • EU Regulation No 1334/2008 on food flavorings
    • GB 2760-2024 National Standard (China) for use in food flavorings

    Typical usage ratio

    • 0.05%–0.2% in flavor blends (adjusted based on final aroma intensity and matrix)

    Downstream process integration

    • Enter as a key reactant in flavor compounding reactors, followed by dilution, mixing, and finishing according to batch protocol

    Final product types

    • Commercial food flavor powders, beverage flavor emulsions, tobacco essences, and aroma bases for bakery and dairy sectors

    2. Pharmaceutical Ingredient Synthesis

    As an advanced intermediate, this compound forms the core scaffold of several active pharmaceutical ingredient (API) classes, including certain iron chelators and flavor-masking agents used in oral dosage forms. Strict documentation of purity, elemental impurities, and trace solvents is critical for downstream formulation, and users incorporate it in GMP-controlled synthesis modules to secure regulatory approval for finished APIs and intermediates.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF Monographs for relevant API classes
    • European Pharmacopoeia General Monograph 2034
    • cGMP requirements, including full traceability and impurity profiling

    Typical usage ratio

    • Variable as determined by API synthesis route; generally 1–1.5 molar equivalents relative to amine or acid components per batch

    Downstream process integration

    • Implemented in the cyclization or condensation stage of multi-step API synthesis, followed by purification, crystallization, and QC release

    Final product types

    • Deferiprone (iron chelator), various flavor-masking excipients, and advanced starting materials for custom APIs

    3. Food Additive Manufacturing

    Downstream processors employ this material as the immediate precursor for approved food additives such as maltol and ethyl maltol, contributing sweet, toasty aroma in finished foods. Industrial food additive plants demand precise impurity control, low heavy metal content, and consistent batch-to-batch color when incorporating this feedstock in their continuous or batch esterification and hydrogenation lines.

    Industry compliance standards

    • FAO/WHO JECFA (Joint FAO/WHO Expert Committee on Food Additives) Specifications
    • U.S. 21 CFR §172.515 – Synthetic flavoring substances and adjuvants
    • China GB 1886.84 (Maltol for food processing)
    • ISO 22000 Food Safety Management System

    Typical usage ratio

    • Typically 98% by mass as maltol precursor, balance made up of catalysts or co-reactants; adjusted for conversion yields in downstream reactors

    Downstream process integration

    • Fed as a starting reagent in batch or continuous reactors for maltol or ethyl maltol synthesis, followed by crystallization and spray drying for standardized additive output

    Final product types

    • Refined maltol, ethyl maltol, and customized sweet flavor blends for confectionery, dairy, bakery, and beverage industries

    4. Fine Chemicals & Chelating Agents

    The unique pyranone structure allows downstream use as a chelation-active intermediate in specialty fine chemical production, such as iron chelates for plant nutrition and analytical reagents. End users select this material to ensure reliable reactivity and stable chelate formation under varying pH and ionic strength, which is essential for both agrochemical and laboratory reagent markets.

    Industry compliance standards

    • REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals, EU)
    • OECD Guidelines for Testing of Chemicals
    • ISO 9001:2015 Quality Management for chemical intermediates
    • Relevant national legislation for chelating agents and micronutrient use in agriculture (e.g., Regulation (EC) No 2003/2003)

    Typical usage ratio

    • 0.5–2.5% w/w depending on metal ion concentration and desired chelation strength

    Downstream process integration

    • Charged into blending vessels during chelate formation, often in aqueous or alcoholic solution, prior to neutralization and solid separation

    Final product types

    • Iron-maltol complexes for micronutrient fertilizers, trace metal analytical standards, and laboratory diagnostic reagents

    5. Specialty Polymer Additives

    In advanced polymer and packaging films sector, downstream formulators add this material to improve thermal processing performance or introduce functional odor-masking layers. Exact dosing and dispersion methods are critical to maintain clarity and mechanical stability in films, especially in multilayer barrier packaging for sensitive food applications.

    Industry compliance standards

    • EU Regulation 10/2011 on plastic materials intended to come into contact with food
    • US FDA 21 CFR 177.1520 (Olefin polymers with additives)
    • Japanese Positive List System for Food Contact Materials
    • ISO 9001/ISO 14001 for polymer additive manufacturing

    Typical usage ratio

    • 0.01–0.3% by weight in masterbatch formulations, adjusted based on dispersion uniformity and food contact migration limits

    Downstream process integration

    • Dosed during masterbatch compounding or direct blending with resin pellets prior to film extrusion or injection molding

    Final product types

    • Anti-odor multilayer films, specialty food packaging liners, and odor-absorbing polymer masterbatches
    Free Quote

    Competitive 3-Hydroxy-2-Methyl-4H-Pyran-4-One prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    3-Hydroxy-2-Methyl-4H-Pyran-4-One: Practical Perspectives from the Manufacturer

    Direct Experience with 3-Hydroxy-2-Methyl-4H-Pyran-4-One

    In the chemical manufacturing world, operational knowledge sets real producers apart from trade-only operations. Our team has managed every aspect of 3-Hydroxy-2-Methyl-4H-Pyran-4-One production for clients who value stability, full transparency, and consistent quality. Over the years, we have fine-tuned synthesis protocols, invested in process improvements, and solved practical issues from raw material sourcing to final drying and packaging. This level of control lets us engage directly with users—flavorists, researchers, and material scientists—ensuring every batch meets intended applications rather than relying on off-the-shelf deliveries.

    Properties Worth Understanding

    The unique structure of 3-Hydroxy-2-Methyl-4H-Pyran-4-One, sometimes called a derivative of maltol, combines a pyranone ring with well-placed hydroxyl and methyl groups. This combination gives rise to a distinctive aroma profile, robust flavor modifying attributes, and notable chelating abilities. Users may value its gentle caramel, bread crust, or fresh cotton candy olfactory notes, depending on the concentration and matrix. We maintain product purity above 98 percent, checked regularly by HPLC, as even small quantities of side-products or impurity can shift aromatic balance and reactivity.

    Some manufacturers might focus on bulk output without considering that certain byproducts, including higher carboxylic acids or aldehydes, interfere with downstream uses. In our experience, even mundane choices—like the choice of catalyst or drying method—affect both the chemistry and practical results for end users. We monitor these during every batch, not just at the endpoints, to provide stability in both sensory and technical applications. Unlike more aggressive analogs, our preparation preserves the functional hydroxyl group, making the compound compatible with a wider range of food, cosmetic, fragrance, and even pharmaceutical matrices.

    Specification Integrity from Production to Delivery

    Most conversations about specifications focus only on numbers. Our experience shows that meeting a data sheet is just the start. We target tight melting point range, minimal residual solvents, and fully characterized polymorphism in every consignment. We document not only assay but particulate profile, crystal size distribution, and trace residuals. This level of detail comes from years of fielding questions around blendability, dissolution rates, and perceptible color shifts in final formulations. Regular review of our analysis protocols allows us to adapt as our customers’ needs change.

    Through direct collaboration with flavor houses and analytical labs, we have confirmed that those using generic or poorly purified 3-Hydroxy-2-Methyl-4H-Pyran-4-One often see problems at the formulation stage: haze in solutions, off-odors after storage, or inconsistent release in encapsulated systems. Our rigorous QC program includes accelerated stability trials under heat and humidity, because real-world conditions rarely follow the ideal.

    Model and Lot Consistency

    Industrial users sometimes worry about batch-to-batch drift, especially for high-sensitivity flavor and fragrance jobs. Our process tracks key synthesis parameters and keeps a historical bank of reference samples from every lot. By comparing each run to prior gold standards—across spectrum, smell, and solubility—we anchor quality. Some clients request specific particle grades or pre-dissolved systems; we consult directly to determine if a standard specification fits or whether a custom grind, hydrate, or co-crystal variant would serve better. Over time, such customizations often become new benchmarks for broader adoption.

    The value in maintaining a living archive of product runs sits in the ability to quickly trace root causes of any anomaly. Should a user flag a sensory deviation, it takes hours, not weeks, to compare with retention samples, review full batch history, and pinpoint whether time, transport, or formulation is the source. This process not only resolves issues quickly but also strengthens future runs.

    Practical Usage Scenarios

    Most requests for 3-Hydroxy-2-Methyl-4H-Pyran-4-One arise from the flavor and fragrance sector, followed closely by health-related research teams. Our experience supporting both large and small manufacturers makes clear that application shapes the required grade. Food technologists often use it to manipulate sweetness or mask bitterness in stevia blends, chocolate analogs, caramel varieties, and cereal coatings. Here, clarity and odor purity matter more than ever; unwanted sulfur or residual solvents can push flavor over the edge or cause costly product rework.

    Outside food, the compound finds a role in personal care items—from enhancing “warmth” notes in perfumes to stabilizing aroma oils against oxidation. We have also supported material scientists experimenting with 3-Hydroxy-2-Methyl-4H-Pyran-4-One as a chelating agent in metal capture or controlled-release matrices. Because this molecule forms stable complexes with transition metals, it opens up formulation options in colorants or active ingredient carriers for other sectors.

    These application-driven approaches surfaced many “hidden” discovery points over the years. For example, one beverage customer traced an unwanted color shift to minute iron contamination binding with the product; our team responded by refining purification to push trace metals far below standard food-grade thresholds. Another personal care developer found that submicron particle sizing increased fragrance longevity and minimized sedimentation in clear cosmetic oils. This kind of problem-solving, based directly on direct feedback, guides how we continue to innovate on both standard and tailored forms.

    Notable Differences from Similar Products

    A question we often hear relates to the difference between 3-Hydroxy-2-Methyl-4H-Pyran-4-One and other similar pyranone derivatives, like maltol or ethyl maltol. From a chemist’s point of view, subtle shifts in atomic arrangement lead to meaningful changes in both organoleptic performance and chemical reactivity. 3-Hydroxy-2-Methyl-4H-Pyran-4-One imparts a more pronounced “toasted” or “caramelized sugar” note compared to the sweeter, gentler impression of maltol or the punchy, almost artificial profile of ethyl maltol.

    Stability under storage and pH also diverges. Our monitoring shows 3-Hydroxy-2-Methyl-4H-Pyran-4-One resists breakdown in acidic systems better than several analogs. End users working in soda, citrus, or acidified food applications report fewer sensory drifts over time when compared to standard maltol. In cosmetic systems, the difference emerges in color stability and resistance to yellowing, especially in transparent gel matrices. For technical and research applications, its chelation ability outpaces maltol, broadening its utility for tasks involving transition metal binding.

    Some labs, focused on antioxidant properties, use our high-purity 3-Hydroxy-2-Methyl-4H-Pyran-4-One as a model compound for radical scavenging studies. The stronger complexation with iron and copper compared to base maltol provides an avenue for further research into shelf-life extension or oxidative stabilization, especially in high-value nutraceuticals or bioactive ingredient preserving systems.

    Addressing Common Issues and Challenges in Handling and Use

    Successful long-term supply of 3-Hydroxy-2-Methyl-4H-Pyran-4-One requires more than basic batch approval. Over the years, we have helped end-users solve a range of decoction, dissolution, and stability issues. Temperature, humidity, and exposure to light play a measurable role in product performance. We recommend moisture-barrier packaging and have tested multi-layer pouches and drums to minimize hydrolysis during transport. Our own transit simulation tests confirm that even a brief spell at high humidity can cause caking—a solvable issue with proper material handling guidance and improved anti-caking agents.

    Handling practices in production-scale use show the value of training. We have documented best practices for weighing, transferring, and mixing to ensure reproducibility in both pilot and full-scale runs. Small changes in batch sequence or mixing order can lead to clumping or reduced dissolution, especially in high-solids applications or where quick breaks in agitation occur. By direct site visits and staff training, we have helped several plants recover processing efficiency and reduce costly downtime.

    One recurring subject is the control of product color. Beyond just meeting the “white to slightly yellow crystalline powder” expectation, the objective remains to deliver a material free of microburns and microscopic dark flecks. These defects can result from overzealous drying or sudden shifts in pH during isolation. We use lower-temperature drying ovens and in-line pH control to cut down on thermally derived color bodies, addressing what one beverage client described as “invisible but impactful” quality detractors.

    Waste minimization and sustainability also attract attention. Our team has improved yield by careful solvent recovery and has worked to minimize energy footprint per kilogram of finished product. By capturing reaction byproducts and reusing wash water, we have not only shrunk our own environmental impact but also promoted cleaner, cost-effective options for our partners in the supply chain.

    The Real Way Forward: Integrating User Feedback and Scientific Progress

    Engaging directly with partners, rather than just delivering bulk shipments, gives us a first-hand window into what works—and what falls short. For example, end users in food flavoring have pushed for sensory mapping across tens of different matrices; their notes convince us to review trace contaminants, focus sharply on headspace aroma analysis, and chase down causes for “clean” versus “dull” sugar notes. One candy maker highlighted the interplay between manufacturing line heat and product volatility, which led us to adjust our supply chain to minimize transit at critical temperature thresholds. This close loop between field use and factory practice underpins every new tweak or standard update.

    Regulatory compliance and full traceability get constant attention. While 3-Hydroxy-2-Methyl-4H-Pyran-4-One doesn’t face the same scrutiny as some novel ingredients, the direction of travel across global agencies points toward more frequent audits and expanded testing requirements. Our lot-level records and willingness to submit for third-party analysis mean that product recalls or compliance questions find rapid answers, not bureaucratic delays. As food, cosmetic, and pharmaceutical firms face tougher limits on impurities, our own acceptance criteria grow stricter in parallel.

    From time to time, universities and early-stage start-ups approach us for research-scale support or deeper technical advice. Drawing on decades of in-house documentation, we can rapidly pull literature, analytical reports, and application studies, enabling innovative new uses that stretch beyond the traditional flavoring and scent categories. Recent collaborative research led to experimental composites and encapsulation systems harnessing the chelating and aroma features of 3-Hydroxy-2-Methyl-4H-Pyran-4-One in new technical domains.

    Fostering Trust: What Works Best for Long-Term Partnerships

    Real trust builds over meeting demanding challenges, not just filling orders. As actual producers, we understand that a product like 3-Hydroxy-2-Methyl-4H-Pyran-4-One enters sensitive systems, from mass-market foods to medical research pipelines. Any unexplained variation or sudden supply chain glitch can derail entire projects. We address these risks by maintaining detailed logs for every run, flagging microtrends before issues emerge, and investing in better stability studies. Sharing results and tools—like real-time tracking links, reference spectra matching, or case-specific guidance—cements our reputation as problem-solvers, not just suppliers.

    Taking advantage of feedback, we rolled out technical bulletins covering practical topics such as optimal dissolution protocols, blending methods in bulk, and shelf life strategies under varied conditions. Collaborating directly with users—whether on test kitchen trials or pilot plant tinkerings—often uncovers pain points not obvious to outsiders. Addressing these concerns directly and tracing back through the production cycle leaves our team better equipped to tackle future challenges.

    Continuous Improvement: Innovation at Every Level of the Process

    In our day-to-day operations, innovation often means refining seemingly minor process steps, such as switching to a greener extraction solvent that slashes residual levels or deploying faster in-line monitoring tools for purity checks. These choices might not make headlines, but they pay real dividends for both product and partners.

    We encourage internal experiments, from batch scalability studies to exploring downstream processing adjustments that yield finer powders or modify dissolving behavior. Fielding custom requests points us toward new application spaces—like slow-release scent carriers, buffered antioxidant blends, or early-stage pharmaceutical intermediates. New challenges shape not only what we produce but how we produce it, keeping the product both relevant and reliable.

    For suppliers actually invested in their own chemical processes, continuous improvement remains more action than slogan. We track, measure, publish, and adjust, every step backed by real lab data rather than marketing promise. That technical heritage forms the backbone of every lot of 3-Hydroxy-2-Methyl-4H-Pyran-4-One that leaves our plant doors.

    Conclusion: From Raw Material to End Use, Experience Counts

    From bench scale discovery to full-scale production, 3-Hydroxy-2-Methyl-4H-Pyran-4-One presents a landscape shaped by real experience. By investing in direct customer relationships, crystalline process control, and relentless attention to detail, we ensure that every user—whether in food, fragrance, or research—receives what they actually need. Practical awareness, open communication, and ongoing refinement remain the foundation for reliable, effective partnerships in the chemical industry. Like any specialty compound, this product demands hands-on involvement and shared insight at every stage. Our ongoing commitment is born of that shared journey, not just a badge stamped on a drum.