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3-Furoic Acid

    • Product Name 3-Furoic Acid
    • Alias 3-Furancarboxylic acid
    • Einecs 209-614-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    476719

    Cas Number 488-93-7
    Molecular Formula C5H4O3
    Molecular Weight 112.08 g/mol
    Iupac Name Furan-3-carboxylic acid
    Appearance White to off-white crystalline powder
    Melting Point 133-136°C
    Boiling Point 277°C
    Solubility In Water Slightly soluble
    Density 1.429 g/cm³
    Pka 3.25
    Structure Contains a furan ring with a carboxylic acid group at the 3-position
    Synonyms 3-Furan carboxylic acid, 3-Carboxyfuran

    As an accredited 3-Furoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 3-Furoic Acid, 100g: Supplied in a sealed, amber glass bottle with tamper-evident cap, labeled with hazard warnings and product details.
    Shipping 3-Furoic Acid is shipped in tightly sealed containers, protected from moisture, heat, and direct sunlight. Packages are clearly labeled with hazard information. Standard shipping follows regulations for chemical substances, ensuring safe handling and transport. Appropriate documentation accompanies each shipment to comply with legal and safety requirements.
    Storage 3-Furoic acid should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers and bases. Protect it from direct sunlight, moisture, and extreme temperatures. Ensure proper labeling on the container and keep it out of reach of unauthorized personnel.
    Application of 3-Furoic Acid

    Applications of 3-Furoic Acid in Industrial Manufacturing

    3-Furoic acid acts as a multifunctional intermediate across several industrial sectors. Its chemical structure offers unique reactivity for synthesis, modification, and stabilization of finished goods. Below we specify real-world applications, detailing supply chain use, technical requirements, and downstream process details.

    1. Pharmaceutical Intermediates for Active Ingredients

    3-Furoic acid is a key reagent for manufacturing specific heterocyclic APIs, including certain anti-inflammatory and antimicrobial agents. Its carboxylic function supports amide and ester bond formation during core molecule construction stages. Pharma manufacturers use it where regioselectivity and controlled purity are critical for downstream transformations or crystallization steps.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • EU GMP Part II
    • USP/NF Monograph (for related substances reference)
    • Ph. Eur. reference standards for impurities

    Typical usage ratio

    • 0.1–0.5 molar equivalents in condensation steps, adjusted based on target intermediate requirements
    • Content tracked to <0.1% w/w in final API per compendial limits

    Downstream process integration

    • Feeds directly to amide and ester coupling reactions in GMP manufacturing suites
    • Involved at early route selection and impurity mapping phases in process R&D
    • Removed or crystallized out after forming the core heterocyclic scaffold

    Final product types

    • Nonsteroidal anti-inflammatory drugs (NSAIDs) intermediates
    • Antimicrobial API scaffolds
    • Pharmaceutical-grade bulk intermediates

    2. Food Contact Resin Modification

    3-Furoic acid is used as a comonomer in furan-based polyester or polyamide resins for food contact packaging. It provides thermal stability and barrier properties as an alternative to other aromatic acids without introducing substances of high regulatory scrutiny. Packaging manufacturers select this intermediate for specialty films and containers requiring migration and extractable compliance.

    Industry compliance standards

    • FDA 21 CFR 177.1500 (Polyester Resins for Food Contact)
    • EU Regulation No 10/2011 on Plastic Food Contact Materials
    • BfR Recommendations for food packaging
    • ISO 22000 for food safety management

    Typical usage ratio

    • 1–8% by weight based on total acid monomer feed in co-polymerization
    • Adjusted for desired gas permeability and mechanical property targets

    Downstream process integration

    • Dosed during melt-phase or solution-phase polycondensation process
    • In-line monitored for end-group conversion and residual acid removal
    • Supports control of resin molecular weight and film clarity

    Final product types

    • Food packaging films
    • Coextruded multilayer containers
    • Thermoformable resins for rigid packaging

    3. Agrochemical Synthesis and Herbicide Derivatives

    Major agrochemical synthesis routes use 3-furoic acid to build selectivity-inducing substituent scaffolds in herbicide and fungicide actives. The acid group enables site-specific modifications and precision placement of furan rings in the molecule, which can contribute to enhanced field persistence or uptake characteristics. Process chemists apply it in early-stage intermediate manufacturing with attention to regulatory residue requirements in the final formulation.

    Industry compliance standards

    • FAO/WHO Food and Agriculture Pesticide Specifications (FAO specification limits for residual raw material)
    • US EPA 40 CFR part 158: Data requirements for pesticide chemicals
    • REACH Annex IX for intermediate registration
    • ISO 9001:2015 for agrochemical production

    Typical usage ratio

    • 0.2–1.5 molar equivalents depending on active structure target
    • Strict content caps at <0.05% in formulated product according to residue guidelines

    Downstream process integration

    • Reacted at stage two or three for heterocycle ring functionalization
    • Feeds batch synthesis reactors with temperature-controlled processes
    • Unreacted portions removed by crystallization or liquid-liquid extraction

    Final product types

    • Selective herbicide actives (furan-substituted analogs)
    • Crop protection intermediates
    • Fungicidal bulk chemicals

    4. Performance Coating and Cross-Linking Agent

    Coatings manufacturers employ 3-furoic acid as a functional cross-linking block in specialty coatings and varnishes, including waterborne systems. The acid improves hydrophobicity and chemical resistance in cured polymer matrices. Formulation chemists use it where regulatory VOC content and durability must align with stringent market expectations for professional and industrial finishes.

    Industry compliance standards

    • Directive 2010/75/EU (Industrial Emissions Directive, VOC limits)
    • ASTM D3359 for coating adhesion
    • ISO 12944 corrosion protection for steel structures
    • RoHS for hazardous substances restriction

    Typical usage ratio

    • 3–7% by solid resin weight
    • Adjusted per end-use performance requirements and cross-link density

    Downstream process integration

    • Added during resin synthesis or as post-modifier in prepolymer stage
    • Mixes with other multi-functional acids or alcohols for desired film properties
    • Cured with heat or light-activated catalysts

    Final product types

    • Industrial anti-corrosion coatings
    • Metal primer systems
    • Protective UV-cured varnishes

    5. Specialty Flavors and Fragrance Ingredient Synthesis

    In the flavors and fragrance domain, regulated quantities of 3-furoic acid provide structural functionality for formulating specialty furanone derivatives and aroma chemicals. Producers select this input for controlled transformation to flavor constituents with GRAS status or listed under relevant regional flavoring directives, taking care to comply with batch record-keeping and traceability mandated by authorities.

    Industry compliance standards

    • 21 CFR 172.515 (FDA – Synthetic flavoring substances)
    • EUFIC list of permitted flavoring substances
    • IFRA Standards for fragrance safety and purity
    • HACCP systems for ingredient traceability

    Typical usage ratio

    • 0.05–0.3% by final batch volume for conversion to furanone aroma molecules
    • Lot-specific adjustments based on flavor system and targeted organoleptic profile

    Downstream process integration

    • Entered at the initial synthesis of lactone and furanone frameworks
    • Undergoes catalytic reduction, cyclization, or esterification in dedicated reactors
    • Subject to repeated purity checks for residual parent compound

    Final product types

    • Natural-identical flavor ingredients (furanones)
    • Complex aroma formulation bases
    • Fine fragrance blend intermediates
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    Certification & Compliance
    More Introduction

    3-Furoic Acid: Putting Experience into Every Batch

    There’s a practical satisfaction that comes with handling a material like 3-Furoic Acid. This isn’t just another box on a catalog list. Over years of producing it, our team has gained a certain respect for what this organic acid can do on a shop floor, in a reactor, and down the pipeline. Customers come for its functional qualities, but we’ve seen the real benefits play out where chemistry meets daily work.

    The technical name is 3-Furoic Acid, sometimes called 3-carboxyfuran by those closer to the research bench. The CAS number is well-established: 488-93-7. As an aromatic heterocyclic carboxylic acid, this compound brings a quiet versatility to the table that many overlook if they focus only on the more media-hyped raw materials. Over years of manufacturing, we’ve tuned our processes to turn out a product that holds up even in demanding environments.

    3-Furoic Acid appears as pale, crystalline powder—easy enough to scoop and measure, with a tangible texture that any lab technician recognizes straight away. The structure features a furan ring with a carboxylic group at the third position, which gives it particular reactivity. While this might sound like academic chemistry, the result in the field is what matters: reliable results in esterification, straightforward coupling reactions, and solid performance across many applications.

    A Straightforward Choice for Industry

    Veteran formulators, process engineers, and bench chemists use 3-Furoic Acid across diverse settings. Its most prominent role is as a building block for pharmaceuticals and fine chemicals. We have supplied it to customers working on non-steroidal anti-inflammatory drugs and other specialty projects. The carboxylic group placement leads to useful transformations—amide formation, salt production, additional ring substitutions—without onerous side reactions. This reduces batch variability, cuts out extra purification steps, and brings some predictability into scaling up from beaker to batch reactor.

    The food and flavor industry relies on 3-Furoic Acid for its subtle aroma additives. It bridges the gap between pure furan derivatives and more pungent acids, offering a softer note that blends into complex formulations. We work closely with QA teams who check off each analysis before the drums even leave the loading dock. Their priorities are purity, consistent melting point, and minimal color shift—all of which we monitor with each lot produced.

    This compound finds another life in performance materials. Resin manufacturers value it for introducing polarity and thermal stability to specialty polymers. The furan ring structure is less prone to oxidation than some aromatic analogs and stands up in both harsh and delicate modifications. Here, practitioners need a reliable source of 3-Furoic Acid not only for laboratory prototypes but for full-production runs. This means controlling particle size and minimizing moisture content, both of which influence downstream processing and the final product’s performance profile.

    Model and Lot Consistency: Why It Matters

    We have learned from long hours and repeat orders that minor variations in a batch can ripple downstream—turning procedures that work on a small scale into troubleshooting headaches in production. Our 3-Furoic Acid process relies on both trained eyes and well-maintained equipment. Fundamental controls keep specifications tight, so each shipment delivers on the trust customers place in us. We pay attention to melting range, acid content, residual solvent levels, and trace impurities that can affect reaction profiles or colors in finished products. Our staff tests each batch against a standard reference, not only for regulatory compliance but for the peace of mind that comes with consistency.

    We don’t just ship what the market demands; we listen to the daily realities of those buying our product. High-purity grades, usually above 99%, fit the needs of pharmaceutical and specialty chemical firms, while standard grades work well for customers with broader tolerance. In-house testing, including HPLC, GC, and IR, ensures each order matches the agreed specification. This approach reduces out-of-spec complaints and repeat phone calls—something both we and our customers appreciate.

    What Sets 3-Furoic Acid Apart?

    Practitioners often compare 3-Furoic Acid to its isomer, 2-Furoic Acid. Structurally, these look similar—both have a furan ring with a carboxyl group, but the position makes a world of difference in chemistry and downstream uses. Many find that our 3-position acid introduces different reactivity in formation of esters or amides, giving products unique thermal profiles or solubility advantages. We always encourage direct testing, yet the consistent experience is that 3-Furoic Acid offers a combination of selectivity, gentler reaction conditions, and a distinctive flavor or odor profile.

    Price-conscious buyers sometimes ask why not substitute with more common aromatic acids. Benzoic acid, for instance, comes up often. Our response is simple: substituting changes the outcome, not just the economics. The distinctive electronic arrangement in 3-Furoic Acid enables specific coupling, predictable hydrogen bonding, and processing advantages—especially in demanding pharmaceutical syntheses and specialty polymer production. Years working with quality auditors and R&D chemists have shown us that the right raw material makes downstream hurdles easier to clear.

    Our track record with custom modifications comes from requests by process development teams looking for a certain performance parameter. Some want particle size limits below 150 microns; others need ultra-high purity or specific drying protocols. Real-world trials have proved that even small differences in 3-Furoic Acid morph into major changes in reactor run times, color developments, or shelf life of the final product. We support these with batch-specific data, not just generic claims.

    Sourcing and Manufacturing: Lessons Learned

    The real test of any raw material is how it performs outside controlled laboratory conditions. We draw our experience not only from fine organic synthesis, but also from the hands-on difficulties that arise during scale-up. Early years included plenty of troubleshooting—filter clogging, odd coloration, reactivity shifts under humidity. Addressing these in practice, not just on paper, built a reliable production process. Today, we use robust furan oxidation and selective carboxylation, followed by a controlled crystallization and careful drying. Small-scale innovations, once proven in-house, are gradually implemented on the full line so customers always receive what their own lab reports tell them to expect.

    We source raw furans with an understanding of upstream volatility; furan pricing swings have taught us to maintain a resilient, geographically diversified supply chain. Our plants follow strict quality standards aligned with major regulatory lists, meeting the benchmarks for fine chemical synthesis. This means more than ticking off box compliance. Each order comes with full traceability, batch data, and responsive support from staff who know the product’s quirks and strength. Our approach helps customers with vital documentation during audits and streamlines regulatory submissions—less time explaining, more time producing.

    Because fine chemical manufacturing rarely pauses for supply chain hiccups, our logistics team monitors not only inventories, but also regional shipment patterns and import regulations. This keeps deliveries trustworthy and keeps customers’ lines running whether the end use is food, pharmaceuticals, resins, or intermediate synthesis. Relationships formed over years mean we anticipate needs and can adjust capacity to handle seasonal spikes or unplanned surges.

    Supporting Responsible Production

    Our process engineers have spent time on sustainable practices. We minimize waste and emissions during synthesis by recycling solvents and optimizing crystallization steps to lower water usage. Continuous improvement comes directly from operator feedback—implementing closed-loop controls, improving energy efficiency, and finding better ways to recapture heat and solvents. These aren’t academic exercises; tight regulations and real environmental commitments shape every decision.

    Analytical chemists on our staff look at not only the main product, but also how trace residues behave over storage time or during further reactions. For downstream users, these insights help avoid unwanted byproducts or unexpected regulatory headaches. Many customers ask for validated stability data as a part of their own submissions. We’ve incorporated this into our routine, knowing it adds a layer of insurance for both sides.

    Common Challenges from the Trenches

    One lesson learned through decades of work with 3-Furoic Acid is that even the best raw material can go off target when stored or handled poorly. We remind every team that this acid prefers sealed packaging away from moisture and bright light. Improper storage can lead to subtle color shifts or minor degradation, which show up months later as unexplained issues in end-use. To prevent this, we use lined drums, double-sealed bags, and rapid shipment cycles to limit product exposure. Our logistics crews train with these practices in mind, recognizing the details that make a difference in quality on arrival.

    The other recurring challenge comes in the handoff between R&D and scale production. Small-lot lab syntheses may work fine with a broad-purity grade, but ramping up to full production highlights the value of tight impurity controls and reproducible melting points. We routinely work with customer technical staffs to fine-tune specifications, so that the batch-to-batch experience matches the chemistry needed—and no one is left troubleshooting after a line stoppage. Communication with procurement and QA teams on their side is as important as the in-lab protocol. Our experience tells us that early coordination, transparency, and shared data resolve most downstream hurdles before they start costing time or material.

    Building Trust through Consistency

    In our experience, trust builds not with slogans but through timely deliveries, transparent batch data, and willingness to address feedback head-on. Many customers send us updates after trial runs, pointing out where a specification adjustment saves them several steps or cuts rework. We respond by refining our own process, validating what works at scale, and delivering improved product with the next run. This feedback loop doesn’t happen overnight; it comes from shared investment in getting the fundamentals right.

    We invite long-term customers to review our facility audits, sit in on live batch runs if required, and discuss their own process headaches. Time spent on the ground with user teams brings out insights that lab data might miss—subtle shifts in color, dustiness, or a handling challenge that only shows up in heavy production. These details filter straight into production and QC so that each barrel matches not just technical specs, but also the real-life demands of their operation. New customers often remark on this difference after comparing to bulk commodity suppliers.

    Down-to-Earth Questions We Hear Every Week

    One recurring question concerns 3-Furoic Acid’s shelf life. Our records—and those of regular buyers—show stable performance up to three years from date of manufacture, so long as the product is stored dry and sealed. Some users push past that if storage is ideal, but we stand by routine retesting for older inventory. Another common inquiry focuses on special forms—requesting micronized grades, denser compacts, or tailored moisture content for specific process needs. While customization increases lead time, it saves more time in the long run by reducing on-site adjustment and improving batch-to-batch uniformity.

    Sometimes we’re asked about food-grade or high-purity designations. In these cases, we supply COAs and full documentation for food or pharma applications, with batch-by-batch tracking and detailed analysis. This transparency keeps audits smooth and removes guesswork from end-use registration. The difference shows when new customers familiarize themselves with our retained samples and witness how our procedures adapt to new regulatory frameworks—no last minute scrambles for missing data or paper trails.

    Users also want assurances in global sourcing. Pricing volatility, border controls, and access to timely shipments affect everyone from inbound ingredient managers to on-the-floor operators. Our answer is simple: relationships with multiple vetted raw material sources, forward planning, and willingness to adjust lot size or packaging to meet the realities of changing markets. This approach kept production running during border disruptions, natural disasters, and the odd global crisis.

    Continuous Improvement and Looking Ahead

    Experienced staff know no process stays perfect forever. Feedback from the field shapes ongoing tweaks to our production and quality protocols. Automated monitoring and better data capture make a difference. We use this information, along with direct customer feedback, to refine not only our chemistry but also all the practical parts—packaging, delivery, and documentation. This means looking for even small improvements that make life easier on the customer’s end, such as improved bag linings for drier storage or better labeling for safe handling.

    Regular training and cross-team reviews keep us aligned with ever-tighter regulatory standards. Questions that weren’t even asked five years ago—such as trace impurities at sub-ppm level, or batch isotope analysis—are now common. We stay ahead by benchmarking against the best global producers and incorporating advanced analytics that spot potential issues before they escape the plant gates. Real collaboration between operators and chemists in our facility means no lab is guessing; they know exactly what’s inside each barrel, every time.

    We have always found value in working directly with customers on process integration. Some new applications develop out of side conversations—where a customer faces a sticky synthesis or wants to test a greener route to a long-standing product. Our willingness to modify drying cycles, particle sizes, or even packaging formats gives end-users a smoother transition when adapting existing protocols to their own lines. This acts as a bridge between boutique and bulk, allowing specialty projects to scale without retraining or costly process overhauls.

    Practical Value and the Road Forward

    For us, manufacturing 3-Furoic Acid isn’t just filling drums to spec—it’s about reliability, communication, and taking responsibility for all the moving parts that bring the compound from reactor to real-world use. Our customers’ success stories often come not from the expected, but from the hard-earned adjustments, quick troubleshooting, and willingness to refine both product and partnership over time. Seeing a pharmaceutical launch, a new resin on the market, or a specialty flavor breakthrough with our raw material brings a sense of accomplishment that only comes from consistent, hands-on effort.

    Over years of work, we’ve learned that answering the practical questions—about purity, supply, shelf life, and process impact—matters far more than a brochure filled with buzzwords. What matters is delivering 3-Furoic Acid that meets needs every day, not just on paper but in each operator’s hand, in every QA manager’s record, and on every production line. We believe that the real measure of value is the smooth, predictable performance our product gives, shaped and proven by the many hands along the way from production to application.