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3-(Dimethylamino)Benzoic Acid

    • Product Name 3-(Dimethylamino)Benzoic Acid
    • Alias 3-Dimethylaminobenzoic acid
    • Einecs 211-373-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    532267

    Chemical Name 3-(Dimethylamino)benzoic acid
    Molecular Formula C9H11NO2
    Molar Mass 165.19 g/mol
    Cas Number 99-68-3
    Appearance White to off-white crystalline powder
    Melting Point 157-159 °C
    Solubility In Water Slightly soluble
    Density 1.17 g/cm³
    Pka 4.1 (carboxylic acid group)
    Pubchem Cid 7397
    Iupac Name 3-(Dimethylamino)benzoic acid
    Smiles CN(C)C1=CC=CC(=C1)C(=O)O
    Storage Temperature Room temperature
    Hazard Statements Irritant

    As an accredited 3-(Dimethylamino)Benzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100g amber glass bottle labeled "3-(Dimethylamino)Benzoic Acid," features hazard symbols, CAS number, and secure screw cap closure.
    Shipping 3-(Dimethylamino)benzoic acid is shipped in tightly sealed, chemical-resistant containers, protected from moisture and light. It is handled by trained personnel, according to standard hazardous material regulations. Packaging adheres to UN shipping guidelines, with clear labeling. Transportation is via certified carriers, ensuring safety and compliance with all applicable chemical shipping laws.
    Storage 3-(Dimethylamino)benzoic acid should be stored in a tightly sealed container, protected from light, moisture, and incompatible materials such as strong oxidizers. Store it in a cool, dry, and well-ventilated area, ideally at room temperature. Ensure proper labeling and keep it away from flames or heat sources, as well as from areas accessible to unauthorized personnel.
    Application of 3-(Dimethylamino)Benzoic Acid

    Applications of 3-(Dimethylamino)Benzoic Acid in Industrial Manufacturing

    3-(Dimethylamino)Benzoic Acid provides valuable structural and functional benefits throughout key sectors in advanced manufacturing. As the direct producer, we support global partners by maintaining consistent specification control and batch traceability specific to downstream technical demands. Below, we outline precise deployment details and regulatory guidance for critical application scenarios, grounded in real-world customer feedback and standards adherence.

    1. Pharmaceutical Intermediate for Local Anesthetics

    This material serves as a crucial intermediate during the synthesis of several ester-type local anesthetics, especially when producing agents such as dimethocaine and analogous benzamide derivatives. Manufacturers integrate it into the condensation step with acid chlorides or esterification reactions, where purity and trace amine control affect downstream pharmacological outcomes. Our technical support addresses compliance audit documentation with a focus on pharmaceutical grade parameters from raw intake through API yield.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • USP and EP monographs for related intermediates
    • FDA 21 CFR Part 211 (Current Good Manufacturing Practice for Finished Pharmaceuticals)
    • China Pharmacopoeia (for domestic and Asian supply chain partners)

    Typical usage ratio

    • 0.8–1.2 molar equivalents per targeted anesthetic synthesis batch, based on process-specific stoichiometry; formulation adjusts for impurity control and scalability.

    Downstream process integration

    • Charged to reaction vessels during multi-step syntheses for local anesthetic precursors, typically after base-catalyzed acylation or esterification steps and prior to downstream quenching, purification, and crystallization.

    Final product types

    • Injectable and topical local anesthetic APIs (e.g., dimethocaine, isocaine derivatives)
    • Bulk pharmaceutical intermediates
    • Finished dosage forms (ampoules, gels) after further synthesis and formulation

    2. Synthesis of Functional Dyes and Optical Brighteners

    Widely adopted as a key amine-bearing aromatic acid building block, this compound underpins downstream synthesis of cyanine, rhodamine, and hemicyanine dyes. Its electron-donating group and adjustable reactivity are valued during condensation and coupling stages, allowing consistent hue and stability in high-spec photonic and textile dye applications. End-use product quality in this market directly ties to input raw material batch uniformity and trace ionic content.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (for textiles)
    • ISO 9001 for quality management in pigment and dye manufacturing
    • REACH Regulation (EC) No 1907/2006 for registration, evaluation and use in Europe

    Typical usage ratio

    • 5–15% of total dye batch charge, precisely adjusted according to target wavelength, chromophore intensity, and downstream fiber or substrate compatibility specifications.

    Downstream process integration

    • Fed as a primary or auxiliary aromatic precursor during azo-coupling, condensation, or amidation reactions; typically dissolved in aqueous/organic phase prior to downstream sulfonation or quaternization stages and dye isolation.

    Final product types

    • Cyanine and rhodamine class colorants for fabrics
    • Optical brighteners for detergents and cellulose-based materials
    • Laser and printer toner dyes
    • Data storage disc coatings employing lightfast photonic dyes

    3. Corrosion Inhibitor Synthesis for Metalworking Fluids

    In industrial metal finishing and coolant blending, 3-(Dimethylamino)Benzoic Acid acts as an intermediate for the preparation of specialized corrosion inhibitors, particularly where amine-carboxylate ligands are needed to chelate and stabilize active metals. Customers achieve targeted passivation layers that balance protection, foam control, and downstream reactivity with machining oils or water-based systems.

    Industry compliance standards

    • ASTM D4627 (Standard Test Method for Iron Chip Corrosion for Water Dilutable Metalworking Fluids)
    • ISO 6743-13 (Lubricants, industrial oils and related products classification)
    • REACH (for European customers using corrosion inhibitor packages)

    Typical usage ratio

    • 3–8% by weight in corrosion inhibitor formulations; dosage refined based on coolant type, metal substrate, and regulatory maximums for residual aromatic content.

    Downstream process integration

    • First introduced into a pre-neutralization reactor before forming complexing salts or surfactant adducts, then blended into emulsion or semi-synthetic coolant concentrates for fire-off and deployment at metalworking sites.

    Final product types

    • Chemical concentrate corrosion inhibitors for advanced machining operations
    • Lubricating fluids for high-precision cutting, stamping, or forming
    • Protective transit and storage oils for ferrous and non-ferrous metals

    4. Photographic Chemical and Imaging Formulation

    In specialty photography and print imaging chemistry, this aromatic acid supports the synthesis of electron transfer agents and spectral sensitizers required for silver halide and other specialty photoactive emulsions. Its dual functional groups offer process chemists a reliable handle for acylation and dye-linkage steps, contributing to consistent spectral absorption, shelf stability, and grain refinement in light-sensitive coatings.

    Industry compliance standards

    • ISO 18902:2013 Imaging materials – Processed imaging materials – Albums, framing and storage materials
    • ISO 5-4:2009 – Density measurements in photographic industries
    • IEC 60432-3 (Photographic lamp safety, for indirect compliance)

    Typical usage ratio

    • 0.5–2.5% wt in manufacturing emulsifier dyes or coupling agents, evaluated in lab-scale trial runs to match desired photo-response curve and coating thickness of the final assembly.

    Downstream process integration

    • Blended into the sensitizer formulation during batch or continuous mixing, followed by in situ coupling with silver salts or organic activators within the emulsion compounding phase and subsequent coating onto photographic base material.

    Final product types

    • Color photographic paper coatings
    • Inkjet and digital imaging specialty films
    • Emulsified layer chemicals for archival photographic and medical x-ray films

    5. Specialty Polymer Modifiers for Coatings and Adhesives

    As a unique aromatic acid modifier featuring a dimethylamino substituent, this material finds precise use in the preparation of functionalized polyamides, polyesters, and epoxy resin blends. Downstream manufacturers use its nucleophilic site in chain extension reactions, surface-activating end-capping agents, or imidization steps, imparting improved antistatic characteristics, dyeability, or adhesion on treated substrates.

    Industry compliance standards

    • ISO 9001 and ISO 14001 for coatings and resins manufacturing
    • RoHS Directive 2011/65/EU for electronics and industrial adhesives
    • ASTM D882 for polymeric film tensile properties (relevant for performance characterization)

    Typical usage ratio

    • 0.2–1.0% by mass in resin modifier masterbatches or as a terminal group reactant; tailored to polymer backbone and desired surface attributes, with lab-based adjustment depending on Solids Content and Glass Transition Temperature (Tg) targets.

    Downstream process integration

    • Fed directly into melt processing extrusion, solution polymerization, or in the final blending phase for crosslinked adhesives; may require nitrogen-purged kettle system to minimize premature oxidation prior to downstream curing and compounding.

    Final product types

    • Antistatic coatings for electronic components
    • Specialty adhesive films for automotive or industrial laminates
    • Dye-receptive polyester fibers and engineering plastics
    • Crosslinked structural composites for electronics or aerospace
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    Certification & Compliance
    More Introduction

    3-(Dimethylamino)Benzoic Acid: Product Introduction from a Manufacturer’s Perspective

    About Our 3-(Dimethylamino)Benzoic Acid

    Making 3-(Dimethylamino)Benzoic Acid in our facility means dealing with real reactions, tangible purity demands, and hands-on QC work. From raw material sourcing to the final packed drum, the entire process happens under our roof. The appearance of this compound – a pale white to slightly off-white powder – reflects the standards we maintain batch after batch. As a direct manufacturer, we know every detail of its molecular character: C9H11NO2, with a molecular weight that weighs in at 165.19 g/mol. The CAS number 99-68-3 points straight to this identity, and our production matches every technical point expected by those who use the compound in labs or at industrial scale.

    Purity, Consistency, and the Day-to-Day Challenges

    Every shipment written off under our batch log comes from real work on actual reactors, not a distribution spreadsheet. We run HPLC purity checks, GC-MS for trace analysis, and verify that the melting point falls within the agreed range. In our plant, scaling up means managing solvents and temperatures without cutting corners, which keeps impurity profiles predictable. Purities above 99% are the norm, and we can handle requests for tight controls on heavy metals, water content, or residual solvents.

    Customers working in pharmaceuticals, dyes, agrochemicals, and analytical chemistry want guarantees. We deal with requests like, “We need 50 kg for synthesis trials, can you ship with a full certificate of analysis and origin?” From our end, that means running another round of analytical checks before sealing the drums. Handling those details protects our own name as much as it serves the user at the other end.

    Manufacturing Experience and Real-World Product Knowledge

    Anyone moving chemicals at scale knows how small variances become large problems. Over time, we’ve built up process know-how that reduces variables in every run. You want to avoid hot spots in the reactor, solvent residues under the allowed limits, and maintain pH tightly during crystallization. Our technical team refines work-up steps because issues in the post-run could echo in purity loss or a needle-like crystal structure that makes packing tough. Knowing how to dry the product effectively – without causing yellowing or caking – reflects the hour-by-hour attention that doesn’t show up on glossy brochures.

    Each production record draws on years of adjustments. Perhaps we had a batch last year with slightly higher secondary amine levels, so we modified the amination feed rate and used a new water quench method. Details like these turn what appears to be a textbook synthesis into repeatable reality, and that experience cannot be replaced by outsourcing.

    Understanding Application: From Synthetics to Sensitive Diagnostics

    3-(Dimethylamino)Benzoic Acid does not stay on a shelf for long; customers come for it with clear ideas. In pharmaceuticals, teams use it as a building block for drug intermediates where side-group electronics matter. As makers, we’ve seen those customers push us for ever tighter controls on nitrosamine precursors or insistence on certain solvent residues under pharma guidelines. Meeting European Pharmacopoeia and US standards requires us to adapt our cleanroom protocols, filtration steps, and container handling.

    In the dyes industry, researchers prize its electron-rich aromatic ring to produce tailored colorants. Analytical chemistry users reach for this compound as a reagent, sometimes using it directly for pH-sensitivity studies or as part of complexometric assays. One customer needed material for coupling reactions in solid-phase peptide synthesis and requested assurance that our product came free from common benzoic acid isomers, reducing the risk of chain-termination during their synthesis.

    Even agrochemical formulators request this compound, leveraging the dimethylamino group for unique pesticide or herbicide scaffolds. Others use it to shape library molecules in discovery projects. By keeping the same compound consistent batch after batch, users can match spectroscopic signatures without recalibrating methods, saving both time and money. When a customer approaches us to audit the facility before regulatory approval, we walk them through both our process and our analytical detection methods, giving internal labs absolute transparency about what goes into their pipeline.

    What Sets Our Product Apart?

    Direct manufacturing builds advantages that can’t be matched by third-party intermediaries. We handle the raw aniline upstream, manage the methylation grades, and use in-house crystallization. By keeping everything in-house, the product avoids multiple handlings, repackaging, or variation driven by inconsistent logistics. For example, storing crude intermediates at the right humidity allows us to minimize decomposition, limiting unwanted by-products.

    When resellers repackage or hold compounds longer than intended, peroxide formation or isomer shifts can creep in unnoticed. In our setup, product often moves directly from reactor to drum, with minimal dwell time. That’s where the difference stands out to end-users who run critical tolerance-level assays or require lot-to-lot repeatability. Our staff keeps lines clean, schedules maintenance before bottlenecks hit, and reviews historical production data to catch patterns of drift. Real stories like these set manufacturers apart from those who just pass boxes through inventory.

    Handling Specifications and Meeting User Demands

    We regularly face questions about variations from different end-users, from R&D chemists wanting analytical lots in glass bottles to production engineers ordering by the ton. Some want the lowest chloride possible; others stress photostability or ask about UV cutoff points. Our inventory team works with planners and the lab to segregate lots, mark for special orders, or quarantine material until all parameters pass.

    Specs change over time—one year, a customer orders with no more than 0.05% water; the next year, demand shifts to focus on trace metal content. Accommodating these changes requires actual adjustment in process, not just a new label on the drum. Sometimes the difference between a failed and a passed release comes down to 30 minutes longer drying or a minor tweak in the pH adjustment step.

    Failing to meet a physical attribute request can mean a returned shipment or, worse, an upset partner. We value feedback – both complaints and compliments – because that real-world test drives improvement more than any internal audit.

    Logistics and Packaging: Details That Reflect Experience

    Owning every step from reactor to loading dock lets us solve practical problems on the spot. Our team selects packs based on the product’s hygroscopicity: for long-distance shipments, we use sealed, foil-lined drums and deploy silica gel packs to keep the powder from clumping or yellowing. Clear lot numbering on every carton matches directly to the analytical record, supporting robust tracking. Traceability comes from internal systems, not a third-party ledger.

    Our ship-out crew checks weight, settles powders to avoid shipment losses, and personally signs off on the final seal. These operational routines make sure customers worldwide encounter the same product properties, whether a kilo flies to an R&D lab or a metric ton leaves for industrial futures. Behind the scenes, logistics comes with its own chemistry: temperature swings, customs, regulatory compliance, and documentation for local and international standards.

    Regulatory Compliance and Product Documentation

    As the manufacturer, we deal directly with regulatory bodies and know the steps involved in registering products for different territories. Each shipping order leaves our facility with supporting documentation. Our quality assurance team compiles not only the Certificate of Analysis but also material traceability, and if required, full dossiers supporting REACH or other local obligations.

    With long-term customers, compliance checks involve an open exchange: audits, supplier questionnaires, factory visits, and mutually agreed corrective action lists. No third-party intervention muddies the process – communication happens directly between product engineers and users’ technical staff. Addressing actual site specifics, from effluent handling to GMP procedures, goes beyond compliance and shapes ongoing, practical improvement.

    Technical Support from a Manufacturer’s View

    We field technical questions daily. Our team gets queries about solubility in mixed solvents, compatible reaction partners, or custom packing to reduce exposure in sensitive syntheses. The real advantage comes from our chemists’ hands-on knowledge, honed by actually running each process step.

    Some customers use 3-(Dimethylamino)Benzoic Acid as a precursor in multi-step reactions and ask about minimizing contamination from orthogonal isomers. Others focus on the electrical effects of the dimethylamino group and want to discuss subtle differences in reactivity under varied pressure or temperature. We support those deep-dive discussions because our own staff has faced those experiments and knows the underlying chemistry.

    Responding to Process Disruptions and Batch Failures

    Tough days happen. Sometimes an unexpected impurity appears in the profile, or the product picks up a tint. That’s not a hypothetical concern in a real plant; it’s a Tuesday morning. Our approach: stop shipping, rerun the checks, and communicate the situation. The point isn’t claiming perfection. Instead, it’s taking ownership, troubleshooting fast, and learning from the experience to tighten control.

    Past process upsets have taught us that an extra filtration step or improved nitrogen blanketing can resolve issues before they escalate. By maintaining direct communication with users, we keep expectations realistic. Customers rely on that transparency: better an honest explanation and adjusted timeline than an unreliable product.

    Comparing with Alternative Products and Competitors

    Many compounds function as aromatic acids with amine substituents, but 3-(Dimethylamino)Benzoic Acid carves its niche through both its solubility and reactivity. We’ve compared results side-by-side with para and ortho analogs – they show differing pKa, melting range, and UV absorption. Some buyers have tried switching to para-form, only to find their downstream chemistry responds differently. Our own experiments show even slight differences in substitution pattern affect intermolecular interactions and thus the final yield or color of target products.

    Compared to similar bench-reagent acyl donors or standard benzoic acids, our product regularly shows a narrower melting range and repeatable spectroscopic fingerprint. Customers comment on the speed at which their colorometric assays stabilize with our acid, an edge supported by minimized trace contaminants and proper packing.

    Sustainability in Production

    Managing byproducts and solvent recovery in our factory is a hands-on challenge. We invest energy into waste minimization, driving solvent circulation, and optimizing reaction efficiency. Responsible chemical management isn’t just a slogan – it shows up in the measured volumes of spent wash, the closed containers for hazardous residue, and the recorded numbers at the effluent treatment station.

    Decisions affecting sustainability balance between product purity, operator safety, and running costs. Our engineers experiment with alternative water sources for washing steps or recover overhead distillates in side loops. Each cycle of improvement is driven by the real output – less waste out, stronger product out. Adopting green chemistry where feasible, following legal disposal, and documenting our eco-footprint turns aspirational policies into workaday routines.

    Continuous Improvement and Earning Trust

    Every product we send out the door becomes a reference point for what our company stands for. The strength of 3-(Dimethylamino)Benzoic Acid’s reputation comes from customers who return a year later, pushing for even higher standards or bigger volumes. Continuous improvement is not just about tightening SOPs but listening to what users experience at the bench or on the line. They drive us to pare down moisture, cut out side-impurities, or schedule deliveries that fit unforgiving deadlines.

    Over the years, the greatest praise comes not from industry awards or technical bulletins but repeat business and honest feedback. Knowing that a ton delivered last quarter matched the kilo shipped last week testifies to a cycle of reliability that’s earned by doing the work right—consistently, openly, and with real pride in the chemistry that happens on our floors.