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3-Chlorobenzyl Cyanide

    • Product Name 3-Chlorobenzyl Cyanide
    • Alias Chlorobenzyl cyanide
    • Einecs 214-429-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    360900

    Chemical Name 3-Chlorobenzyl Cyanide
    Cas Number 10217-34-2
    Molecular Formula C8H6ClN
    Molar Mass 151.59 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 254-256 °C
    Density 1.18 g/cm3
    Refractive Index 1.552
    Flash Point 116 °C
    Solubility In Water Insoluble
    Smiles N#CC1=CC(=CC=C1)Cl
    Pubchem Cid 157542
    Storage Conditions Store in a cool, dry, well-ventilated place

    As an accredited 3-Chlorobenzyl Cyanide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100-gram amber glass bottle with a secure screw cap, labeled “3-Chlorobenzyl Cyanide,” includes hazard and safety information.
    Shipping 3-Chlorobenzyl Cyanide is shipped as a hazardous material due to its toxic and irritant properties. Transport requires compliant, secure packaging with appropriate hazard labeling. Shipment must adhere to relevant regulations (such as DOT, IATA, or IMDG), and transport by qualified carriers with shipping documents and Material Safety Data Sheet (MSDS) included.
    Storage 3-Chlorobenzyl cyanide should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from heat sources, open flames, and incompatible substances such as strong bases, oxidizing agents, and acids. Store away from direct sunlight. Properly label the container and keep it in a chemical storage cabinet designed for toxic and volatile chemicals. Use secondary containment if possible.
    Application of 3-Chlorobenzyl Cyanide

    Applications of 3-Chlorobenzyl Cyanide in Industrial Manufacturing

    As an established manufacturer with long-term downstream partnerships, we supply 3-Chlorobenzyl Cyanide (3-CBC) to a range of advanced industrial sectors requiring specialized intermediates. Below, we outline major B2B manufacturing applications, including regulatory standards, industrial formulation practices, functional integration in process flows, and resulting end products in each domain.

    1. Agrochemical Intermediate Synthesis

    Leading agrochemical producers incorporate 3-CBC as a key intermediate during multi-step synthesis of selective herbicides and insecticides, especially for compounds in the arylnitrile and phenoxyalkanoic acid classes. Our material enters the process primarily via nucleophilic substitution or coupling reactions, ensuring controlled conversion and minimal side-product formation. Process chemists monitor purity and isomer content due to strict toxicological profiling required for actives registration across global agricultural markets.

    Industry compliance standards

    • European REACH Regulation (EC) No 1907/2006 for chemical safety
    • US EPA Pesticide Registration (FIFRA compliance)
    • China Pesticide Registration (ICAMA)
    • ISO 9001 and ISO 14001 certified production traceability

    Typical usage ratio

    • 5–12% molar input relative to core herbicide/insecticide backbone, adjusted based on specific active ingredient synthesis

    Downstream process integration

    • Introduced during early-stage active ingredient assembly prior to halogenation or cyanation steps
    • Acts as starting material in custom synthesis for contract manufacturing organizations (CMO)
    • Subject to in-line purity checks via HPLC and GC analysis

    Final product types

    • Herbicide technical concentrates (e.g., arylnitrile compounds)
    • Systemic insecticide technical material
    • Pre-mixed pesticide formulations for cereal and oilseed use

    2. Pharmaceutical Intermediate for Active Ingredient Production

    Major pharmaceutical groups select our high-purity 3-CBC mainly for heterocyclic intermediate construction, notably in synthesis of certain antihypertensive and psychotropic APIs. This raw material enters multi-step organic syntheses, where careful reagent weighting and minimization of trace contaminants directly affect final impurity profiles. Strict adherence to pharmacopoeia requirements and GMP documentation supports audit trails for regulated drug substances.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (Ph. Eur.) and US Pharmacopeia (USP)
    • 21 CFR Part 211 for finished pharmaceuticals
    • ISO 9001 traceability management

    Typical usage ratio

    • Typically 1.5–4% molar equivalent depending on API synthetic pathway, adjusted for batch or continuous flow processes

    Downstream process integration

    • Utilized in early-stage cyclization or condensation reactions forming heterocyclic API cores
    • Subject to residual solvent and byproduct monitoring per ICH Q3C/Q3D
    • Full analytical profile required for DMF submission

    Final product types

    • Active pharmaceutical ingredients for cardiovascular and CNS therapies
    • Key intermediates for contract API manufacturing
    • Regulatory-compliant pharmaceutical starting materials

    3. Fine Chemical Building Block for Liquid Crystal Material Synthesis

    Producers of electronic-grade liquid crystals use our 3-CBC as a building block during the synthesis of biphenyl, cyanophenyl, and related mesogenic compounds. Tight control of isomer purity is essential, as even minor traces impact optical anisotropy and switching characteristics in liquid crystal displays (LCDs). Downstream engineers monitor each input to meet device veneer requirements in high-tech display fabrication.

    Industry compliance standards

    • RoHS Directive (2011/65/EU, Annex II)
    • International Electrotechnical Commission (IEC) 61249-2-21 standards
    • ISO 9001 and QC per electronics supply chain requirements
    • Independent batch traceability for major display panel OEMs

    Typical usage ratio

    • Ranges from 2–8% mass fraction in liquid crystal precursor synthesis, based on final phase requirement (nematic, smectic, or cholesteric)

    Downstream process integration

    • Fed into organic synthesis steps for mesogen and dopant formation
    • Reaction conditions optimized for minimum impurity carryover
    • QC release according to LC purity and optical rotation parameters

    Final product types

    • Advanced liquid crystal monomers and oligomers
    • Blend components for TFT-LCD and OLED panels
    • Specialty reactive mesogens for electrical and optical films

    4. Dye and Pigment Intermediate Manufacturing

    In specialty dye and pigment manufacturing, 3-CBC functions as a strategic intermediate for the development of cyanine, anthraquinone, and azo-based chromophores. Our product achieves high reactivity with defined stoichiometry during condensation or substitution reactions, critical for color strength and stability in performance-grade dyes. Quality control teams monitor residual chlorine and cyanide content to meet environmental benchmarks and downstream product safety.

    Industry compliance standards

    • EN 71-3:2019 for heavy metals in finished dyes/pigments
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals) v3.1
    • ISO 9001 and ISO 14001 for pigment production management
    • REACH Annex XVII compliance (restricted substances)

    Typical usage ratio

    • 5–15% of the total aromatic input for dye synthesis, tailored to molecular design of final pigment

    Downstream process integration

    • Entry point as a primary aromatic precursor in dye molecule coupling
    • Continuous monitoring during colorant condensation steps
    • Pilot plant and scale-up evaluated for eco-toxicological compliance

    Final product types

    • High-performance pigments for inks and coatings
    • Cyanine dyes for industrial textile processing
    • Specialty colorants for plastic and fiber applications

    5. Chemical Intermediate for Polymer Additive Production

    Polymer additive formulators employ 3-CBC as a precursor for the synthesis of stabilizers and UV absorbers intended for advanced plastics, including polycarbonates and polyesters. Accurate dosing and quality verification ensure low residual content and predictable performance in weather-resistant plastics intended for engineering, packaging, and automotive uses. Manufacturing audits focus on input verification, as well as release testing of final additive purity and migration limits.

    Industry compliance standards

    • EU Regulation (EU) No 10/2011 for plastics intended for food contact
    • US FDA 21 CFR 177 for indirect food additives
    • ISO 9001:2015 quality management for polymer additives
    • UL Yellow Card listing for flame-retardant grades

    Typical usage ratio

    • 1–6% of additive molecular composition, dependent on polymer matrix type and expected lifetime of UV and thermal exposure

    Downstream process integration

    • Incorporated during initial additive synthesis before compounding with base polymer resin
    • Monitored for migration and compatibility with intended plastic formulation
    • Laboratory-scale verification prior to full-scale industrial extrusion or injection molding

    Final product types

    • UV absorbers for outdoor polycarbonate and PET sheets
    • Stabilizing agents in engineering resins
    • Weather-resistant plastic additives for automotive and construction applications
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    Competitive 3-Chlorobenzyl Cyanide prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 3-Chlorobenzyl Cyanide: Direct from Our Production Facility

    Years in Production, Experience Behind Every Batch

    3-Chlorobenzyl Cyanide, model CB-103C, remains a staple in our chlorinated benzyl compound portfolio. Since setting up our first reaction vessels in the late 1990s, daily routines inside our facilities revolve around one clear outcome: total control from raw material handling to end product packaging. A focus on consistency and traceability keeps impurities in check and output standards high, batch after batch. We source benzyl chloride and sodium cyanide through vetted channels with rigorous inspection before they even touch our reactors. Every lot of CB-103C earns its place only after passing real analytical runs in our own lab—the GC, HPLC, and NMR readings don’t lie.

    Looks, Values, and Why It Matters

    In its pure state, 3-chlorobenzyl cyanide forms a crystalline solid or, for some customers, a light-yellow liquid, depending on storage conditions and precise specification. It’s not just about hitting an assay of at least 99%—color, clarity, and melting point often carry real-world consequences for end-product outcomes. We maintain physical parameters such as melting range and solubility tightly inside agreed tolerances, knowing that trusted appearance tells a story by itself in most labs and factories. Our full property sheets are ready for review; here, it’s enough to know that purity and physical characters remain rock-steady year-round.

    That Niche Edge: Where 3-Chlorobenzyl Cyanide Fits Best

    Over decades, one thing stands clear—demand centers around specialty synthesis. Researchers and production chemists come to us for CB-103C when tailoring active pharmaceutical ingredients, advanced agrochemical intermediates, or rare dye precursors. Take a common situation: One client synthesizes targeted fungicide intermediates with specific activity profiles. Even small shifts in reactivity mean the difference between crop resilience and lost value. With our material, they keep yields where they want and quality control running on plan.

    In another field, certain laboratories pursue aryl nitrile-derived ligands or novel aromatic architectures. They discover CB-103C offers a handle for selective substitution thanks to its particular chlorination and cyanation pattern. Whether working with standard nucleophiles or more exotic transition metal catalysts, they report reliable outcomes, cycle after cycle.

    The real message here: Users count on this compound where reactivity, selectivity, and physical predictability matter far more than price per kilo or mere “good enough” labels.

    Focus on Differences: CB-103C versus Other Benzyl Cyanides

    Many people ask us about differences compared to 2-chlorobenzyl cyanide or unsubstituted benzyl cyanide. The placement of that chlorine atom—at the meta position—creates a specific electronic and steric profile. It influences both the reactivity and downstream performance in multi-step syntheses. Our own trials back this up. For example, in certain nucleophilic aromatic substitutions, 3-chlorobenzyl cyanide reacts cleanly, giving fewer unwanted byproducts than the ortho or para isomers. This lets chemists skip extra purification steps or unnecessary waste disposal.

    Then there’s the issue of shelf stability. We’ve charted storage studies over years for all our cyanide series. CB-103C, under controlled temperature and humidity, resists oxidation and hydrolysis surprisingly well—much better than its ortho-chlorinated cousin, and comparable to many unsubstituted analogs. This matters for anyone who works in regions with variable ambient conditions or slower consumption rates.

    From a safety angle, every benzyl cyanide presents typical precautions; no product can sidestep the need for solid protective procedures and containment measures. Still, we build our packaging and documentation around what we know from real field experience. Most accidents happen from lapses in handling or deviant storage, not from a mysterious property of the chemical itself. Our tech service team tracks patterns and offers in-depth knowledge sharing, not just fine print.

    Challenges We See in the Industry

    It’s tempting to treat cyanide compounds just as a line on a supply list. But this field faces recurring challenges: tightening environmental controls affect both process emissions and site waste, tighter documentation standards demand traceable lot histories for every drum or bottle, and global regulatory shifts add new twists every year. As we refine processes, updates from regulators and end-users keep our production and compliance staff thinking beyond routine. In the last few years, we recalibrated solvent recovery pathways to minimize off-gassing, and newer drum handling stations now capture fugitive emissions that used to go untracked at ports or wholesalers.

    Another challenge is maintaining real transparency in an industry that too often pushes traceability onto downstream partners. That doesn’t fly for us. Every bottle gets its production batch code, full analytics, and chain-of-custody record right from our facility floor to recipient’s door. One audit from a multinational pharmaceutical customer put it best—they no longer run repeat identity or fingerprint checks against every delivery, saving them lab time and reducing uncertainty.

    Then there are the subtle issues: shelf-life drift, lab-to-lab variance in melting point readings or GC peaks, and the temptation for some to cut corners with marginal suppliers. We tackle these with routine cross-checks between lines and sites, frequent round-robin analyses with partners, and a culture where every operator knows the chain only stays strong if every link holds. Ask any long-term buyer—we don’t leave these details to hope or luck.

    Solutions That Work: Building From the Ground Up

    Pointing out industry problems means little without action. That’s why our entire setup—from reactor design to packaging room—focuses on minimizing uncontrolled risks and maximizing hands-on involvement. We designed our systems so cleaning solvents never meet product lines, and every batch passes headspace GC screening to detect potential off-odors or volatile traces. On the staffing side, every supervisor and shift chemist owns their sign-off on documentation, so gaps show up early and corrections happen immediately.

    Documentation remains another big focus. Regulatory and customer audits expect more than a baseline certificate of analysis. We maintain dynamic batch records, real-time incident logs, and regular competence checks for our lab team. Our compliance officers interface directly with both shipping and field partners, translating chemical numbers and test outcomes into plain talk that makes sense not just for inspectors, but for frontline workers who actually use the material.

    Continuous feedback, both from clients and internal teams, provides new ideas for product refinement. Simple things—new bottle types for small labs, improved tamper-evident seals, or alternate label languages—can drastically improve daily outcomes. We believe sharing these insights, instead of hiding problems, makes for better and safer outcomes.

    Practical Guidance: Using 3-Chlorobenzyl Cyanide in Modern Industry

    A lot of customers ask about the best ways to store and use CB-103C. Our own experience, plus the lessons from hundreds of client installations, point to a few core habits. Always keep containers tightly sealed, away from direct sunlight and sources of moisture. Dedicated storage cabinets or cold rooms, where possible, keep thermal cycling from aging the product before use. Transfer operations benefit from purpose-built containment stations—spills and airborne losses fall to near zero with the right hoods and absorbent mats.

    On the process side, we’ve watched operational teams succeed through small but consistent moves: pre-dissolving the cyanide in the reaction solvent before contact with hard reactants, running slow additions to manage exotherms, and monitoring pH closely throughout the workup. Records and tracking pay dividends—logging temperature and humidity for both product and facility provides an early-warning system for potential degradation. None of these steps require advanced tools, but commitment to procedure marks the difference between routine and crisis prevention.

    Waste management deserves its own mention. Modern industry pays close attention to cyanide-containing waste streams. We provide dedicated guidance for breaking down residues, neutralizing with oxidants, and running spent solutions through validated destruction units. Some customers even return surplus or expired batches for certified off-site neutralization—a policy we support because safety never takes a back seat.

    End-User Collaboration

    Real partnership with end users drives incremental improvement. Some of our best tweaks to the CB-103C process began as requests from longtime partners: tighter impurity thresholds, tailored particle sizes for slurry operations, shifts in packaging design for robotic handling. Geographically, demands vary—agrochemical firms in South America may want longer shelf lives due to humid storage areas, while research labs in Japan ask for micro-lot supply with full spectral libraries attached. We’ve integrated these needs into our standard offerings, but no batch ships out before a customer’s unique requirement receives a final cross-check.

    Direct communication cuts down on confusion. Instead of anonymous service hotlines or third-party handlers, chemists and plant managers call us and get direct answers from people who make the chemical. Quick troubleshooting, documentation tweaks, and off-cycle quality checks stem from this ongoing dialogue. We’ve found this beats generic help-desk or distributor scripts in nearly every instance.

    We do not claim to have solved all challenges for every application, but field dialogue and shared technical insight bring us closer to the mark each year. From early R&D runs to scale-up batches, open exchange accelerates both problem-solving and innovation.

    Analytics and Product Verification

    Authenticity matters more than ever. Each run of 3-Chlorobenzyl Cyanide receives a full analytical panel: GC for organic purity, NMR for molecular fingerprinting, mass spec for batch-to-batch verification, moisture analysis, and spot checks for heavy metals. If anomalies come up, we dig down fast—cross-checking source material logs, production temperature records, and cleaning schedules.

    Old-school habits—such as pulling spot samples randomly during filling, or verifying cap torque on every shipment—complement the modern tools. These steps grew from years watching little oversights mushroom into bigger issues down the road, whether in color drift, odor changes, or off-nominal reactivity. Audited plants frequently ask for physical inspections; our policy opens the line to all regular customers.

    Through ongoing documentation, regular calibration of equipment, and a constant push for transparency, the resulting CB-103C supply consistently earns customer trust, audit signoff, and repeat orders. It’s a cycle built less on marketing and more on sweat, process, and a refusal to shortcut the little things.

    Building for the Future

    Regulations and user expectations climb every year. In practice, that means reviewing solvent systems for environmental impact, increasing recovery on every high-purity chromatograph, and constantly training staff for emerging workplace and environmental standards.

    In the last year, a concentrated push on waste minimization led us to retool filtration and washing steps, bottling not just higher purity but less waste per kilogram. Feedback from partner plants challenged us to dial in even finer impurity specs, and ongoing lab exchanges let our chemists compare readings across global sites. It’s this willingness to chase improvements and foster real-world connections that keeps the product relevant and trusted.

    Why Direct Manufacturing Really Matters

    There’s a line that runs straight from our raw materials through every reactor, quality lab, and packaging bay, ending with world-class specialty chemical in customer hands. No third-party handoffs, no switching between resellers mid-run—just transparent, accountable production. We believe this long-term commitment, built over decades of field experience, answers not just the needs of today’s chemists but those of tomorrow’s innovators. Anyone in this market sees new use cases in active molecules, digital synthesis, and stricter global rules. Building products with predictability and hands-on care puts us in the front row of industry progress.

    Conclusion: A Product Built On Trust and Experience

    3-Chlorobenzyl Cyanide (CB-103C) represents not just a product by chemical structure, but a promise of long-term capability, partnership, and technical depth. Our work in this space stands on daily practice, deep collaboration with users, and steady solutions to the hard challenges facing specialty manufacturing. Keeping these foundations strong drives us to keep building better products—one batch, one customer conversation, and one atom at a time.