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HS Code |
120848 |
| Chemical Name | 3-Chlorobenzaldehyde |
| Cas Number | 19398-61-9 |
| Molecular Formula | C7H5ClO |
| Molar Mass | 140.57 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 213-215°C |
| Melting Point | -3°C |
| Density | 1.243 g/cm3 |
| Solubility In Water | Slightly soluble |
| Flash Point | 98°C |
| Refractive Index | 1.577 |
| Purity | Typically ≥98% |
| Smiles | C1=CC(=CC(=C1)Cl)C=O |
| Synonyms | m-Chlorobenzaldehyde; Meta-Chlorobenzaldehyde |
| Storage Conditions | Store in a cool, dry, well-ventilated place |
As an accredited 3-Chlorobenzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 500 mL amber glass bottle, sealed with a screw cap and labeled "3-Chlorobenzaldehyde, CAS 3407-42-9, hazardous—handle with care." |
| Shipping | 3-Chlorobenzaldehyde is shipped in tightly sealed containers, clearly labeled with hazard information. It should be transported in compliance with applicable regulations for hazardous chemicals, ensuring protection from heat, moisture, and incompatible substances. During shipping, handle with proper personal protective equipment to avoid exposure, and monitor for leaks or spills throughout transit. |
| Storage | 3-Chlorobenzaldehyde should be stored in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible substances such as strong oxidizing agents. Store in a tightly closed, labeled container made of compatible material. Protect from moisture and keep away from ignition sources. Ensure appropriate safety measures and access to spill containment equipment nearby. |
Applications of 3-Chlorobenzaldehyde in Industrial ManufacturingAs an established upstream chemical manufacturer, we supply 3-chlorobenzaldehyde to a range of industries that demand strict process controls and consistent quality for use in advanced formulations. On this page, we outline the key downstream application scenarios where this raw material plays a defined, regulatory-compliant role in end-product synthesis and manufacturing, emphasizing requirements for compliance, formulation, process integration, and finished product outputs. 1. Pharmaceutical Intermediate Synthesis3-Chlorobenzaldehyde functions as a key intermediate in the multi-step synthesis of several active pharmaceutical ingredients (APIs), specifically in the production of anti-inflammatory, antifungal, and antihypertensive drugs. In these applications, manufacturers utilize the aldehyde group for selective condensation, followed by further transformations such as Grignard or reductive amination reactions. The chemical’s purity and traceability remain critical throughout, with strict batch release protocols to meet the stringent demands of regulated drug synthesis environments. Industry compliance standards
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2. Agrochemical Active Ingredient ManufacturingIn crop protection chemistry, 3-chlorobenzaldehyde is commonly applied as an intermediate for synthesizing specific herbicides, fungicides, and insecticides, especially those requiring electron-withdrawing substituents on aromatic rings. Downstream formulators incorporate it into condensation and cyclization steps, supporting the selective construction of heterocyclic active compounds for targeted agricultural applications. Adherence to environmental and occupational safety standards is mandatory, with batch-specific residue and impurity control. Industry compliance standards
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3. Dye and Pigment Intermediate ProductionDye and pigment manufacturers utilize 3-chlorobenzaldehyde for the construction of complex aromatic compounds via Schiff-base formation and subsequent oxidative coupling. Its electron-withdrawing character allows for vibrant color expression in azo and anthraquinone dye systems. Quality assurance focus lies on precursor purity and the minimization of trace contaminants, as these impact color fastness and migration properties in downstream textile or plastics applications. Industry compliance standards
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4. Fragrance and Aroma Chemical SynthesisWithin the fragrance industry, 3-chlorobenzaldehyde acts as a building block to produce specialty aroma compounds, notably for musk, floral, or green odorant ingredients. Producers employ it in controlled condensation reactions with ketones, followed by reduction or ring closures. Stringent allergen content limits and traceability requirements apply, and formulators control the quality of headspace volatiles through careful purification in final distillation steps. Industry compliance standards
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5. Fine and Specialty Chemicals ManufacturingFine chemical producers employ 3-chlorobenzaldehyde as a substrate for constructing custom molecules used in advanced materials, crosslinkers, and stabilizers in the plastics and specialty coatings industries. The compound’s chemical reactivity enables downstream modifications such as sulfonation and alkylation, supporting the design of performance additives and specialty oligomers. From regulatory and customer audit perspectives, quality assurance focuses on impurity fingerprinting and supply consistency for downstream qualification. Industry compliance standards
Typical usage ratio
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In our factory, we spend each day scaling up chemistry that used to fill a beaker—now it fills drums, tankers, and careers. One of the workhorse building blocks for specialty chemicals, 3-Chlorobenzaldehyde, earns its keep because it hits the sweet spot between reactivity and selectivity. People who work with aromatic aldehydes know it: this compound’s unique combination of a chloro-substituent and a formyl group opens doors for numerous synthetic possibilities. Out on the shop floor, we run batches designed not just to meet a spec, but to hold up under scrutiny when customers turn a keen eye on their downstream chemistry.
Chemists recognize 3-Chlorobenzaldehyde by its clear, slightly yellow liquid, with a sharp, almond-like odor. Its CAS number is 536-90-3. The chlorine atom sitting in the meta position on the benzene ring changes both the electron distribution and the reactivity pattern compared to the more common para (4-) isomer. This seemingly small shift gives you a compound more resistant to oxidation, with a relatively narrow boiling range favoring controlled synthesis. We manufacture to meet industrial-level purity, typically 99% minimum by GC, to hold impurities in check against the demands of flavor synthesis, pharmaceuticals, and agricultural intermediates. Each batch undergoes melting point, refractive index, and spectral checks before it leaves our site—not as a marketing ploy, but from hard-earned lessons about how even a fraction of percent impurity can destroy a downstream yield.
Down the chain, 3-Chlorobenzaldehyde finds regular work as a core intermediate. Our customers’ products touch everything from personal care to crop science. In pharmaceutical routes, this molecule often steps in as a starting material for antihistamines, anti-hypertensives, and other fine chemicals. In agricultural chemicals, its robust reactivity allows tight control when forming heterocyclic cores—where consistency in incoming aldehydes pays dividends during synthesis. Small changes in the aromatic substitution pattern ripple into significant changes in the biological activity of the end product, making source quality more than a trite phrase.
We’ve watched this market shift in recent years. Several of our customers switched from 4-Chlorobenzaldehyde to the 3- isomer to tweak the bioactivity profile of emerging actives. When new regulations clamped down on trace impurities in flavors and fragrances, we tuned our process to slash trace dichlorinated species and benzyl chloride content. If batches veer outside of a UV cut-off, we don’t ship. From years of hitting these marks, our team knows which step impacts each impurity, and how a simple procedural slip during oxidation can show up two months later on a GC trace. We’ve learned that our technical choices echo across continents and portfolios.
At first, aromatic aldehydes may all look similar—purporting interchangeable utility based on structure. That story unravels quickly on the shop floor. 3-Chlorobenzaldehyde offers distinctive benefits over its close cousins. Compared to chlorination in the ortho or para positions, the meta isomer provides a different reactivity with nucleophiles and electrophiles. This translates directly to the types of condensation products and the relative ease or difficulty of forming Schiff bases, oximes, and hydrazones. In flavor and fragrance chemistry, isomer choice can mean everything: ortho substitution carries steric bulk that chokes certain reactions, while para isomers may drift toward uncontrolled byproduct formation. The meta isomer walks a fine line, supporting specificity in reactions prized by creative chemists.
We’ve worked with clients who needed to experiment with every position before dialing in their product’s properties. Our technical department didn’t just supply material; we partnered through long development cycles and stability assessments. The final usage sometimes depended on product behavior during shelf-life simulations—where our consistently low impurity content made downstream processes repeatable and less risky. We can point to a half-dozen multinational launches that started at a bench with our 3-Chlorobenzaldehyde, including sunscreen stabilizers and new anti-fungal seed coatings.
Making good 3-Chlorobenzaldehyde doesn’t just happen. We start from monochlorobenzene, passing through selective formylation—Wohl-Ziegler or Gattermann Koch chemistry, depending on batch needs and waste minimization targets. Temperature, solvent selection, and work-up protocols matter. We run these not from rote but because we’ve mapped the knock-on effects of small shifts in process—residual acid content can cause yellowing, too much base invites hydrolysis and degradation. Our teams plan for maintenance outages, raw material slack, and scale-up runs because consistency rides on more than one person’s memory. Process safety sits at the top of the priority stack; we insist on closed reaction controls and scrubbing of off-gases. The sharp odor, while manageable, underscores why leak prevention gets so much attention in our hazard reviews.
Process improvements emerge from within. A few years ago, our operators flagged a recurring color shift in late-winter batches; working with our lab, we traced it to cooling water contamination and a trace byproduct that suddenly spiked at higher flow rates. Fixing that taught us not to take utility consistency for granted, and led to the inclusion of real-time process analytics. Now, batch records tie changes to specific outcomes, and mid-batch sampling keeps us out in front. Our quality and production data don’t just sit in files—they inform every tweak to our process window.
Over the past decade, regulatory scrutiny toward trace contaminants in key fine chemicals has increased. End-users, especially from the pharma sector, keep tightening their impurity requirements. This trend forced many producers, including us, to revisit old batch protocols and add more precise analytics. In our experience, consistent headspace GC, HPLC, and IR checks, combined with operator-driven visual inspections, matter more than any particular technology. Getting to <0.1% total impurities is not just a mark of modern manufacturing—it’s become table stakes. For downstream customers locking in IP or regulatory registration, batch consistency means product launch or delay. That’s how we approached big system investments: not for show, but because our long-term customers needed the confidence to specify our product for their own audits.
In external audits—either for GMP compliance or corporate social responsibility—we open our process to review. Transparency builds trust far more than brochures. Our staff walk auditors through not just flowcharts but actual operational controls that prevent mix-ups and cross-contamination. Many buyers have been with us for years, because we treat each technical question as a partnership, not a burden. Our long relationships with analysts, regulatory specialists, and R&D teams on the customer side let us spot changes in demand early.
Supply chain interruptions have taught everyone hard lessons recently. During extended raw material shortages, we pivoted to hedged supply contracts and invested in recycling solvents where purity held. Planned scale adjustments helped us honor contracts during pandemic disruptions. We worked closely with logistics partners for temperature and odor management, because a leaking drum spells more than just a shipping headache—it means lost weeks for downstream production. These actions aren’t about grandstanding, they’re responses learned from experience, shaped by years inside chemical plants where planning and response make the difference between growth and trouble.
Chemicals like 3-Chlorobenzaldehyde demand attention to safe handling. Our plant follows established best practices for ventilation, monitoring, and material containment. We train new workers not just on emergency procedures, but on why trace leaks cause big downstream problems—inside and outside the plant. Every shipment kicks off with closed loading systems; our site invests in odor abatement even if regulations only require periodic checks. Community safety is embedded into our training, not just signed off in manuals. We hold recurring workshops with operators, maintenance staff, and dispatch teams to keep risk communication direct and real—no fancy language or corporate gloss.
Disposal routes matter, too. Waste from our batches gets directed to permitted treatment partners and, where feasible, recaptured into other chemical processes. Those cycles took effort and patience to build—years ago it meant extra cost, but the return shows in a license to operate and a reputation for reliability. Our site champions transparent emission reporting, periodic third-party process hazard assessments, and community complaint hotlines. Regulators and customers expect facts, not just claims.
Feedback cycles drive our renewals. We routinely invite technical teams from customer companies to tour our facility and review process data. That open-door approach means troubleshooting starts early. If a batch performance falls short on a new end-use, we reach out for samples and run joint investigations, sometimes reformulating process solvents or purification steps to answer their needs. Specialty chemistry isn’t just “sold and shipped”—it’s built on trust earned by getting the next batch and the next project across the finish line.
Several years ago, a large client flagged isomeric impurities impacting performance in their fragrance applications. Our team worked side by side with their lab, isolating trace formation routes back to raw material variability. By sourcing higher-purity monochlorobenzene and retrofitting filtration units, we slashed impurity carryover. The result was not just a better fragrance intermediate, but a customer relationship that’s lasted over a decade. Each solved problem feeds back to production procedures, raising the bar across our site.
Process optimization doesn’t happen with one-off investments; it’s an ongoing grind. We regularly review solvent and reagent recovery rates, utility consumption, and energy intensity per kilogram made. Waste stream audits and secondary containment checks have helped us catch problems before they grow. Shared learnings move into operator toolkits—the best process tweaks often come from the line, not consultants. During technical reviews, our plant workforce brings firsthand insights about batch anomalies or HVAC quirks that affect sensitive reactivity. From there, we translate lessons straight into chemistry, adjusting run conditions or storage protocols so customers keep seeing the best of what 3-Chlorobenzaldehyde can offer.
End users in pharmaceuticals and high-purity applications demand traceability, not just compliance. We keep detailed batch records for every kilogram shipped, tracking raw material lots, process parameters, and in-process test results. If a customer ever flags a problem, we can trace it to incidents, operator shifts, or even ambient temperature records from the day of production. This level of tracking started because of customer feedback—real-world issues in production, not regulatory mandates—as a way to build certainty across continents and regulatory regimes.
We know how a single off-spec drum can disrupt not just a batch, but an entire product launch. Our technical specialists support end-users through new scale-ups and regulatory submissions, providing data on stability, analysis, and route-of-synthesis to help customers clear agency hurdles. We issue full certificates for each shipment directly from our QA lab, and can supply historical impurity profiles on request. Because many of our partners operate in markets with strict import and registration requirements, we stay active in industry consortia sharing best practices on safe handling, risk assessment, and transport controls. Peer review across sites keeps us honest and ready to answer customer audits.
Projects requiring aromatic aldehydes rarely run smoothly from start to finish. Sometimes unplanned regulatory changes force reformulation; sometimes a critical synthesis step that considered trivial suddenly causes low yield or unexpected off-odors. We take those as learning chances. Close engagement with technical teams keeps us sharp—if a run fails to reach targeted purity or turns up unexpected low-level chlorides, we go back through each stage to pin down the root. Partners tell us often that the ability to sort out issues in real time, without the need for slow formal escalation, sets our plant apart.
As conversations grow about sustainability and “greener” intermediates, we work closely with R&D teams on routes that minimize environmental impact without giving up yield or quality. These partnerships produce incremental gains—small process changes that add up to resource savings and cleaner effluent over time. In a sector where perfection remains elusive, shared goals pull us all forward.
The landscape for aromatic aldehydes continues to shift. Industries now face growing demand for lower carbon footprints, traceability to responsible raw materials, and elimination of compounds flagged by emerging regulatory watchdogs. We see opportunity, not just challenge, in this new era. Upgrading emissions controls, participating in lifecycle studies of our products, and keeping our formulation playbook open to collaboration all help us adapt.
Bringing new 3-Chlorobenzaldehyde applications to life often starts with requirements for higher purity, traceability, and technical support. Our team tracks innovation from bench to factory—watching shifts in catalyst choices, green chemistry approaches, and automated process control. Our advantage stems from blending deep experience in scale chemistry with the flexibility to learn as projects move from lab to tonnage. Over years of manufacturing, we have learned that the decisive factor is often responsiveness: meeting each challenge, each new request, with open data and honest communication. We’ve built a culture of resilience, where problems become case studies for future batches.
Working directly with 3-Chlorobenzaldehyde over so many years shapes not just our skills but our methods. We don't just ship chemical drums; we back our process with data, understanding, and a story running through each reactor, every inspection, and every customer call. Choice of isomer, choice of process, and even choice of dispatch stack up to impact what our partners make next—be that a specialty pharmaceutical ingredient, a crop protection agent, or a new scent profile stepping onto market shelves. With every batch, the proof comes from lived experience: careful process, practical commitment, and a readiness to adapt for each project’s demands. That’s the difference a manufacturer makes, day in and day out.