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HS Code |
427389 |
| Chemicalname | 3-Bromostyrene |
| Molecularformula | C8H7Br |
| Molarmass | 183.05 g/mol |
| Casnumber | 588-72-7 |
| Appearance | Colorless to pale yellow liquid |
| Density | 1.41 g/mL at 25°C |
| Boilingpoint | 220-222°C |
| Meltingpoint | -21°C |
| Refractiveindex | 1.597 |
| Purity | Typically ≥98% |
| Flashpoint | 88°C |
| Solubility | Insoluble in water; soluble in organic solvents |
| Smiles | C1=CC(=CC(=C1)Br)C=C |
| Inchi | InChI=1S/C8H7Br/c1-2-7-3-5-8(9)6-4-7/h2-6H,1H2 |
| Synonyms | m-Bromostyrene |
As an accredited 3-Bromostyrene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 100-gram amber glass bottle of 3-Bromostyrene, sealed with a red screw cap and labeled with safety and chemical details. |
| Shipping | 3-Bromostyrene is shipped in tightly sealed containers, typically made of glass or compatible plastic, to prevent leaks and contamination. The packaging is clearly labeled with hazard information. It is transported under cool, dry conditions, away from incompatible substances, and in compliance with all relevant chemical safety and transport regulations. |
| Storage | 3-Bromostyrene should be stored in a tightly closed container under an inert atmosphere, such as nitrogen or argon, to prevent oxidation and polymerization. It should be kept in a cool, dry, and well-ventilated area, away from heat, light, and sources of ignition. Store separately from oxidizing agents, acids, and bases to avoid hazardous reactions. |
Applications of 3-Bromostyrene in Industrial Manufacturing3-Bromostyrene is a specialized monomer and key intermediate, supporting critical developments in several advanced manufacturing sectors. Below, our technical team details major downstream applications, specifying integration methods, regulatory protocols, and end-use conversions adopted by industrial clients worldwide. 1. Pharmaceutical API Intermediate ProductionInnovators in the pharmaceutical sector use 3-Bromostyrene as a selective synthon for constructing styrene-based scaffolds, especially in the synthesis of CNS-active and anti-inflammatory compounds. The aromatic bromide offers high regioselectivity in palladium-catalyzed coupling (e.g., Suzuki-Miyaura), directly feeding advanced intermediate routes for small-molecule therapies. Downstream partners employ this intermediate in controlled, validated batch and continuous flow systems for regulatory compliance and scale-up flexibility. Industry compliance standards
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2. Agrochemical Active Compound SynthesisProducers of modern crop protection chemistries integrate 3-Bromostyrene into aromatic core elaboration for fungicides, herbicides, and insecticides. The brominated styrene structure allows for successive functional group transformations, improving selectivity and biological persistence. Customers employ robust process controls to manage by-product profiles and ensure residue compliance in the final formulation. Industry compliance standards
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3. Electronic and Optoelectronic Polymer SynthesisNext-generation display, OLED, and printed electronics manufacturers employ 3-Bromostyrene as a reactive monomer for specialty conjugated polymers and copolymers. Bromine functionality enables rapid, high-yielding C–C coupling, critical for achieving precise control over molecular weight and electronic bandgaps. These polymers exhibit enhanced charge transport and photophysical performance, tailored for integration into advanced devices. Industry compliance standards
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4. Fragrance and Specialty Monomer SynthesisFragrance ingredient suppliers use 3-Bromostyrene as a selective aryl precursor for downstream alkylation and cross-coupling, leading to musky, woody, and floral aromatic chemicals. Integration into fragrance synthesis allows unique vinyl-aromatic notes and base structures in proprietary formulations. Strict impurity profiles and batch traceability support regulated markets and premium segments. Industry compliance standards
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5. Advanced Resin and Coating Component ManufacturingManufacturers in the thermoset and specialty coatings industry use 3-Bromostyrene as a functional comonomer, imparting improved adhesion and crosslink density in styrene-containing resins. Its integration facilitates efficient grafting and surface modification, which is essential for formulating coatings with enhanced chemical resistance, electrical insulation, and adhesion to challenging substrates. Industry compliance standards
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Everything we deliver in the chemical industry runs on precision and reliability. Among the dozens of specialty chemicals we manufacture, 3-Bromostyrene stands out, not for flash, but for sheer utility in synthesis and research. We work directly with phenyl-based intermediates, and 3-Bromostyrene is a notable building block, useful for a range of organic transformations. Its CAS number, 20439-54-1, stands recognized across regulatory and research databases, but here on the floor, we recognize it by its crisp, faintly aromatic character and the careful balance required to preserve both purity and volume during every run.
To make this compound, we use freshly distilled styrene and handle NBS bromination under strictly controlled conditions. Safety is not a side-note in the process; we run regular checks on our reaction vessels and handling systems to ensure that sub-ppm contamination stays in check, both for product quality and operator health. This process produces a clear, colorless to pale yellow liquid, with a boiling range we monitor carefully to avoid both degradation and loss of volatiles. The product specifications match what advanced end users expect, especially regarding GC purity and isomeric content, because trace impurities can ruin catalyst beds or poison cross-coupling reactions down the line.
We focus on a minimum of 97% GC purity for 3-Bromostyrene, not because it is a market norm, but because years of feedback from research customers and industrial groups have shown that going any lower introduces headaches. At that level, Pd-catalyzed couplings—heck, even Suzuki or Heck-type reactions—become much more predictable. Failures during those steps waste weeks of labor, so end users need confidence that no unknowns creep in due to side reactions or unaccounted-for stabilizers. Unlike a trader or reseller, we know exactly what goes in every drum or carboy because our QC team maps out every lot, and we don’t blend across syntheses.
Researchers lean on 3-Bromostyrene for synthesis because it holds the bromine handle and active double bond, ready for incorporation into all manner of substituted styrenes, biaryls, or conjugated systems. Polymers, OLED intermediates, fine pharmaceuticals—these sectors draw on bromostyrenes for both their reactivity and the control it gives over molecular architecture. Chemists using our product often push for higher purity, so over the years, we further invested in better fractional distillation, cleanroom handling, and documentation traceability down to the batch level. Direct control of the production chain means we can respond quickly when expectations shift, such as a request for extra low moisture content or tighter residual solvent profiles.
Manufacturing 3-Bromostyrene is similar to making para- or ortho-substituted bromostyrenes but brings its own quirks. The meta substitution pattern in 3-Bromostyrene allows for different reactivity in palladium-mediated reactions compared to its ortho- or para-counterparts. In practice, this difference affects both research and process chemistry; we hear directly from customers who see a clear benefit when the meta isomer structure minimizes undesirable side reactions or steric hindrance in their target molecules. That insight comes not from datasheets, but from working hands-on with the process and responding when users report back on yields and downstream compatibility.
Comparing it with bromobenzene or even dibromostyrene, the presence of the vinyl group and single bromine gives chemists increased flexibility—one end can undergo coupling, the other remains unsaturated for further chemistry. The double bond also brings in potential polymerization issues if the material sits too long or gets exposed to heat in storage. As a result, our manufacturing process has to prioritize stability—nitrogen flushing, inhibitor dosing, and clear labelling with recommended storage temperatures. We employ standard labeling protocols and ship quickly to minimize transit-related risks. Only full control of the supply and shipping detail ensures that the material arrives in the same condition as the day it leaves our line.
Unlike some fine chemicals that tolerate a degree of variation, 3-Bromostyrene’s sensitivity shows up in both production and logistics. Handling large volumes means more heat generation during bromination, and the process must stay within a narrow temperature window to prevent side-product formation, such as unwanted polymerization or over-brominated residues. As producers, we pull intermediate samples and run both GC and NMR analyses to check conversion rates and impurity profiles. Every now and then, a run will throw up unexpected figures—a slight spike in dibromo content, for example—which prompts a halt and a reprocessing review, rather than pushing subpar material forward. That might slow delivery, but real-world outcomes show that uncompromising standards save much more than they cost, both for user yields and our own reputational equity.
We receive requests for 3-Bromostyrene in both kilogram and multi-ton batches. Scaling up requires tanks lined to avoid corrosion and fitted with baffles to maximize mixing while minimizing unwanted local heating. We calibrate dosing systems every quarter and maintain strict batch tracking so that every shipment can be traced from raw material to finished product. Our cleanroom bottling minimizes the introduction of oxygen, which in turn reduces the risk of unwanted oxidation or coloration. Once sealed, we store inventory below ambient temperatures, and we recommend that customers avoid repeated heating cycles that might weaken the stabilizer package and let the product turn yellow or viscous over time.
Users on the ground are not interested in generic product brochures. They want assurance on how the product performs across different applications—especially in medicinal chemistry, specialty polymer synthesis, and electronic materials. 3-Bromostyrene takes a central role here as a cross-coupling partner, especially where the substitution pattern can affect bioactivity or electronic behavior. We see repeated orders from labs working on new OLED materials, since having a highly pure, meta-brominated styrene unlocks less straightforward synthesis routes. In pharmaceuticals, our partners request documentation packs—including residual solvent profiles, heavy metal testing, and photostability data—since regulatory submissions live or die on that kind of detail. As actual manufacturers, we document every data point and stand ready to collaborate on additional analytical testing, should a customer’s process or regulatory environment shift.
Not every application needs the same baseline. Production chemists working in polymers might tolerate trace levels of stabilizers or minor volatiles, but fine chemicals destined for pharma or optoelectronics often require even stricter controls. Over years of supplying this segment, we have adjusted protocols, sometimes tailoring drying steps or adjusting the glassware cleaning process in response to analysis feedback. The direct loop between our QC lab and our production line means product evolution never happens in a vacuum; real user input drives every significant tweak we make.
Operating as a primary producer means taking responsibility at every level—not only for purity and supply, but for responsible sourcing, workplace safety, and environmental load. Brominated intermediates have always come with a raft of health and safety considerations. We have invested in training our production team on all specifics of handling, right down to emergency protocols. Our plant runs regular drills, and we audit our documentation trails regularly, in line with international guidelines for quality management and environmental compliance. Every drum and bottle leaves our site with a complete batch trace, keeping our promise of transparency through the entire chain, which is fundamental to building trust with our customers and partners.
We also take steps to minimize waste and emissions associated with bromination processes. This means recapturing and recycling solvents whenever feasible, neutralizing any acidic effluents before discharge, and working with local regulators for continuous improvement of environmental management systems. Small efficiencies here and there build up: solvent recycling, more efficient vacuum systems, and automated controls that keep batch parameters within tighter limits. With every incremental improvement, we reduce both direct costs and longer-term liability, keeping both our customers and the wider community in mind.
The market for 3-Bromostyrene has grown as synthetic routes for advanced materials have become more sophisticated. Yet, the distinction between commodity-grade and high-purity product continues to matter. We compete on more than just price; it’s the hands-on production experience, full chain custody, and capacity for rapid response that keep customers coming back. Longstanding clients often call us to discuss technical issues with a batch or report an unexpected behavior in their process—the fact that we produce what we ship and can trace every sample lets us deal with those issues directly. Transparency and traceability are far more than compliance buzzwords. They serve as our contract with users who want more than an anonymous drum from a third-party lot.
Our technical support team, trained in-house and connected with the main plant, forms a link between product development and practical application. When a customer’s process moves from lab to pilot plant, we consult on special packaging, alternative stabilizer regimes, or adjusted distillation cuts. Real feedback loops, backed by process data and analytical reports, allow iterative improvement—our team understands the language of process chemistry and application optimization because they have direct visibility on every production step.
Chemical manufacturing never stands still. New downstream applications for 3-Bromostyrene emerge every year, spurred by developments in pharmaceutical scaffolds, next-generation lighting, and specialty polymers. Our lab follows global literature and keeps communication channels open with academic groups and industrial consortia. Demand for ever-cleaner materials, tighter specification limits, and greener manufacturing pushes us to revisit legacy processes. Across the organization, we treat every improvement—be it in energy efficiency, product isolation, or analytical validation—as a pathway to strengthen both our product line and the trust customers place in us.
Direct production experience, an unbroken chain of custody, and a commitment to detail—these define our approach to 3-Bromostyrene. Every lot results from hands-on management at every stage: sourcing raw materials, controlling reaction conditions, maintaining equipment, and training staff. We do not rely on intermediaries to ensure standards; our reputation rests firmly on the product as it leaves our doors. Collaborating with both established industry partners and innovative startups has reinforced one core conclusion: consistent, high-quality chemical intermediates create value far beyond their nominal unit price by securing the integrity of synthetic and material science pipelines.
3-Bromostyrene serves as more than just another halostyrene in our catalog—it exemplifies the intersection of technical challenge, user demand, and supply chain reliability. Working as a direct manufacturer, we handle every stage with the depth of experience and pragmatism that comes only from daily engagement on the shop floor and in the analytical lab. Each batch reflects a careful balance between efficiency, safety, environmental considerations, and rigorous QC, with direct feedback informing ongoing product evolution. We welcome engagement from users who expect more than generic intermediates and value transparency, traceability, and technical backing built on actual manufacturer commitment.