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3-Bromo-2,2-Bis(Bromomethyl)Propanol

    • Product Name 3-Bromo-2,2-Bis(Bromomethyl)Propanol
    • Alias 3-Bromo-2,2-bis(bromomethyl)-1-propanol
    • Einecs 216-885-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    824937

    Chemical Name 3-Bromo-2,2-Bis(Bromomethyl)Propanol
    Molecular Formula C4H8Br3O
    Molar Mass 328.82 g/mol
    Cas Number 3296-90-0
    Appearance Colorless to pale yellow liquid
    Density 2.23 g/cm³ (approximate)
    Solubility In Water Slightly soluble
    Storage Conditions Store at 2-8°C, tightly closed
    Purity Typically 95% or greater
    Synonyms 2,2-Bis(bromomethyl)-3-bromopropan-1-ol
    Ec Number 221-959-7

    As an accredited 3-Bromo-2,2-Bis(Bromomethyl)Propanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 grams of 3-Bromo-2,2-Bis(Bromomethyl)Propanol, sealed with a secure screw cap and hazard labeling.
    Shipping Shipping for 3-Bromo-2,2-bis(bromomethyl)propanol must comply with hazardous materials regulations due to its chemical nature. The product is typically packed in sealed, chemical-resistant containers, labeled appropriately, and shipped via certified carriers. Proper documentation, including safety data sheets, accompanies each shipment to ensure safe handling and regulatory compliance during transport.
    Storage 3-Bromo-2,2-Bis(Bromomethyl)Propanol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from heat, ignition sources, and incompatible substances such as strong oxidizers. Protect from moisture and direct sunlight. Use secondary containment to prevent spillage, and ensure proper labeling. Store at temperatures recommended by the manufacturer, typically at or below room temperature.
    Application of 3-Bromo-2,2-Bis(Bromomethyl)Propanol

    Applications of 3-Bromo-2,2-Bis(Bromomethyl)Propanol in Industrial Manufacturing

    As the original manufacturer of 3-Bromo-2,2-Bis(Bromomethyl)Propanol, we supply this specialty intermediate to established downstream industrial sectors employing controlled halogenation chemistry. The following application scenarios reflect direct integration within validated production environments, emphasizing regulatory compliance, precise formulation ratios, actual processing stages, and commercially proven final products.

    1. Flame Retardant Polyurethane Foam Chemicals

    This molecule serves as a reactive flame retardant monomer in the formulation of flexible and rigid polyurethane foams used in furniture, automotive, and construction. Downstream formulators require halogenated compounds to meet evolving fire safety protocols, and this raw material introduces advanced bromine content into the polymer matrix during the prepolymer blending and polymerization stages.

    Industry compliance standards

    • EN 1021-1/2 (Furniture: Resistance to ignition by cigarettes and matches)
    • FMVSS 302 (Federal Motor Vehicle Safety Standard: Flammability of Interior Materials)
    • GB/T 20286 (China National Standard for Fire Safety in Building Materials)
    • REACH Regulation on flame retardant use (EU; requires Reactivity/Annex XV dossiers)

    Typical usage ratio

    • 3–8% by weight in polyol blends for flexible foam (higher loading for rigid panels; ratio adjusted for desired V-0 rating and mechanical properties)

    Downstream process integration

    • Meticulously metered into polyol premix tanks ahead of isocyanate addition during foam manufacturing; uniform dispersion is critical for fire performance consistency

    Final product types

    • Vehicle seat cushions and dashboards
    • Domestic and contract furniture (sofas, bedding)
    • Thermal insulation panels and spray-applied rigid foam
    • Acoustic foams for transport and architecture

    2. Epoxy Resin Reactive Flame Retardants

    Downstream epoxy producers use this compound as a halogen source for synthesizing advanced flame retardant curing agents and modified resin bases for electronic laminates and coatings. Its three bromine substituents enable regulatory-compliant fire resistance in electrical insulation and printed circuit board (PCB) applications where industry standards prohibit untreated polymer materials.

    Industry compliance standards

    • UL 94 (Tests for Flammability of Plastic Materials for Parts in Devices and Appliances)
    • IPC-4101 (Base Materials for PCBs – Laminate and Prepreg Requirements)
    • RoHS Directive (Restriction of Hazardous Substances in Electronics/PCBs)
    • IEC 60695-2-12 (Glow Wire Flammability in Electrical Devices)

    Typical usage ratio

    • 2–6% by weight as introduced into resin systems (ratio set by target limiting oxygen index, substrate thickness, and electrical isolation requirements)

    Downstream process integration

    • Typically incorporated at the resin pre-polymerization phase; brominated intermediate reacts to form a covalently bound flame retardant segment within the crosslinked epoxy network

    Final product types

    • Multi-layer printed wiring board laminates
    • Protective coatings for semiconductor components
    • Transformer and relay encapsulants
    • Flame-proof cable sheathing and connectors

    3. Synthesis of Biocide Intermediates for Industrial Water Treatment

    This brominated alcohol acts as a key intermediate in the multi-step manufacture of high-activity biocidal molecules, especially for non-oxidizing, bromine-based industrial water treatment agents. Downstream formulators exploit its dual reactivity, attaching other functional groups to produce biocides with precise activity spectra for recirculating cooling waters, process waters, and paper mill applications.

    Industry compliance standards

    • U.S. EPA FIFRA (Federal Insecticide, Fungicide, and Rodenticide Act) Biocidal Active Approval
    • EU BPR (Biocidal Products Regulation) – Permit for Market Access
    • GB 30981-2020 (China Pesticide Registration Regulation for Industrial Biocides)
    • ASTM E645/E645M (Biocide Efficacy and Residual Detection Methods)

    Typical usage ratio

    • As an intermediate, up to 1:1 molar stoichiometry in chloromethylation or further bromination reactions; downstream finished product inclusion levels typically 0.02–0.15% by weight in end-use water systems

    Downstream process integration

    • Introduced in synthesis step following alkylation, serving as a halogen donor before final coupling and purification to produce technical-grade biocidal compounds

    Final product types

    • Non-oxidizing industrial water biocides
    • Cooling tower and heat exchanger scale-control additives
    • Pulp and paper process antimicrobials
    • Closed system plant water treatment packs

    4. Intermediate in Pharmaceutical Synthesis (Non-API)

    This brominated alcohol finds downstream use exclusively as a protected intermediate for active pharmaceutical ingredient (API) side-chain assembly and blocking group installation in commercial GMP-compliant chemical synthesis lines. Pharmaceutical manufacturers utilize its multi-bromide structure for timed deprotection or as a scaffold for further functionalization, supporting large-volume batch and continuous processing methods.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • USP General Chapter <789> and EU GMP EudraLex Vol 4 (solvent and reagent residual specifications)
    • 21 CFR Parts 210/211 (U.S. FDA cGMP regulations for finished pharmaceuticals)
    • Chinese Pharmacopoeia, Section IV (Intermediates for Bulk Drug Synthesis)

    Typical usage ratio

    • Customized per route; 0.8–1.2 equivalents calculated on limiting reactant in multistep coupling or alkylation reactions, controlled to maintain reaction conversion and minimize impurities

    Downstream process integration

    • Fed under inert atmosphere to reactor vessels during non-aqueous phase or solid-phase synthesis; rigorous in-process testing of residuals prior to workup and purification

    Final product types

    • Intermediate building blocks for small molecule APIs
    • Synthetic protecting group precursors
    • Bromoalkyl sidechain motifs for anti-infective and oncology therapies (not as finished APIs)
    • Advanced pharmaceutical fine chemical intermediates

    5. Specialty Polymer Modifier for High-Performance Plastics

    Polymer compounders incorporate this raw material as a specialty modifier to impart flame resistance and controlled reactivity to engineering thermoplastics, particularly for electronics housing, medical device components, and infrastructure cable insulation. Its reactive sites participate in copolymerization or cross-linking, addressing strict standards for electrical safety and smoke generation control.

    Industry compliance standards

    • UL 746C (Polymeric Materials – Use in Electrical Equipment)
    • ISO 1043-4 (Polymer additives – Flame retardants listing and identification)
    • IEC 60335-1 (Safety of Electrical Appliances)
    • CSA C22.2 No. 0.17 (Canadian Standard for Flame Resistance in Electric Wiring Materials)

    Typical usage ratio

    • 1–5% by weight depending on polymer base (ABS, HIPS, PC); adjusted for target glow-wire test outcomes and mechanical modulus requirements

    Downstream process integration

    • Fed into twin-screw extruder premix during masterbatch or compound pellet production; precise control of dosing temperature eliminates off-gassing or incomplete reaction

    Final product types

    • High-voltage cable and wire insulation compounds
    • Molded casings for consumer electronics
    • Connector housings and switchgear parts
    • Medical device enclosure components
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    Certification & Compliance
    More Introduction

    3-Bromo-2,2-Bis(Bromomethyl)Propanol: Practical Insights From Direct Manufacturing

    Introduction to Our Approach

    Our factory has spent years refining both the chemistry and the logistics behind specialty halogenated intermediates. Among these, 3-Bromo-2,2-Bis(Bromomethyl)Propanol stands out in our inventory, not only because of its multifaceted uses, but because of the direct results we’ve observed at each stage of production and customer feedback. There are plenty of ambiguities swirling around fine chemicals sold through endless distribution chains, but our experience comes from the actual tank farms, process units, and purification columns that turn raw materials into high-value compounds. This hands-on clarity matters a lot for reliability and performance.

    Product Characteristics Based on Manufacturing Experience

    Chemically known as 3-Bromo-2,2-Bis(Bromomethyl)Propanol, the product often gets referenced by its structural formula—C5H9Br3O—among process engineers and lab heads. It emerges as a colorless to pale yellow crystalline solid under typical storage, and the material’s purity—frequently demanded at over 98% by weight—is not just a paperwork statistic for us. It’s a figure that represents countless analytical runs we run internally, checking GC and NMR outputs to avoid off-ratio blends and to catch trace bromide impurities before they complicate downstream work.

    We do not treat melting point as a casual reference; it often lands between 70-74°C for our regular batches, and hitting this range consistently has proven to be an early warning system for the rare hiccups that occur in bromination runs or in the purification steps. Moisture content—controlled through vacuum drying and monitored by Karl Fischer titration—needs careful attention, especially since certain applications cannot tolerate much water.

    Why This Intermediate Matters: A Manufacturer’s View

    Our teams learned early that 3-Bromo-2,2-Bis(Bromomethyl)Propanol serves as a key intermediate in synthesizing flame retardants, especially for high-performance polymers and textiles. Many customers in the plastics and fibers sector put unique demands on the reactivity and purity of this material. Offgrade batches have real-world consequences—yellowing in final polymers, inconsistent flame resistance, and waste in production cycles. Through trial, error, and partnership with our buyers, the specifics of manufacturing this compound go beyond theoretical chemistry.

    We always stress the importance of consistent bromine content during processing. The trifunctional bromine structure in this molecule brings elevated thermal stability and excellent incorporation into polymer matrices, compared to more basic monobromo compounds. In our experience, this difference often shows up during extrusion and molding. Customers pushing the limits of their flame resistance standards often switch to this molecule after finding that simpler alternatives fail in testing, especially for demanding electronics or automotive applications.

    Differences Based on Firsthand Comparison

    Some may ask about how 3-Bromo-2,2-Bis(Bromomethyl)Propanol compares to other popular brominated intermediates, such as simple bromoalcohols or dibrominated species. In direct use, we see standout differences. The triple bromination gives a stronger flame suppression effect at equivalent dosages—less additive needed for the same performance. This helps processors cut back on overall loadings, which in turn has positive results on mechanical properties and costs.

    Typical bromoalcohols lack the same functional density, and we’ve watched many a batch fail standard UL-94 flammability tests because the molecular architecture could not support enough bromine atoms without excessive weight or plasticizer-like softening. Our compound sidesteps much of this, striking a better balance between performance and workability. For clients aiming for halogenated intermediates as building blocks in pharmaceutical or agrochemical syntheses, the multiple bromomethyl groups open up variety in downstream functionalizations that would not be possible with simpler monobromo alcohols.

    Manufacturing Challenges and Solutions

    From the manufacturer’s point of view, there isn’t much room for shortcuts in the plant. The triple bromination step often faces issues of selectivity, and we keep a close eye on temperature profiles and reagent addition rates to avoid unwanted side products. Our operators and engineers built much of the process control instrumentation from scratch to ensure reproducibility at scale — not just for laboratory samples, but for drums and bulk shipments.

    Waste management is another real-world concern. We handle considerable amounts of hydrobromic acid evolved during reaction and invest in recovery systems that allow us to recycle or properly neutralize byproducts before discharge. This effort isn’t purely regulatory; better management of byproduct streams improves overall process economics and avoids recurring headaches with waste disposal. For our clients, this has meant more reliable lead times and predictable quality, rather than waiting out mysterious supplier delays.

    End-User Impact Seen Directly

    By dealing with downstream users face-to-face, our team hears repeatedly how minor variations in 3-Bromo-2,2-Bis(Bromomethyl)Propanol specification lead to large swings in end product quality. The high bromine content—almost 75% by mass in the pure compound—lets manufacturers of flame-resistant materials dial in target specifications with less dead weight and fewer processing aids. For advanced applications in electronic casings or automotive interiors, the difference often comes down to passing or failing industry safety codes.

    Unlike some intermediates that live mostly in a lab setting, this ingredient shows its value on a factory floor. Granule color, odor, and even simple density changes can indicate deviations from process set points. Over the years, plant operators have developed rapid in-process checks alongside routine full-panel analyses, so we identify and correct trends early without pausing the entire line. The end users get shipments that slot into their processes right away, instead of chasing unpredictable performance.

    Continuous Quality and Practical Documentation

    Quality assurance stretches further than certificates or neatly typed test results. We believe in batch-specific data: for example, documenting the exact conditions under which each lot was prepared, not just a generic technical data sheet. Many of our clients have visited the site and walked the packaging and QC halls, observing the actual equipment and methods at work. We answer technical inquiries not by quoting literature, but by pulling up real plant logs and analytical charts that show the life cycle of their particular batch.

    Individual shipments often require tailored documentation, depending on user needs. Some industries—especially medical or specialty textiles—demand deeper quantification of trace byproducts, and we run additional analytical panels to meet these requests. We also support customers facing regulatory scrutiny over halogenated materials, preparing submission-ready documentation that passes muster with both internal auditors and external agencies. In practical terms, this reduces project delays and rework for our partners.

    Process Optimization: A Constant Practice

    We do not treat the manufacturing process as a fixed recipe. Over the past decade, our chemical engineers have monitored yield improvements, tracked energy consumption, and tested greener alternatives for solvents. If a formulation can safely substitute a problematic solvent or cut hazardous discharges, we pivot quickly and keep detailed notes on outcomes. These lessons, shared between plant workers and R&D staff, translate into small but important efficiency gains that eventually show up as cost savings or better product quality for our bulk buyers.

    On the ground, this might mean switching out a distillation column tray, adjusting the hold time at specific temperature steps, or automating a mixing phase that was once done by hand. Each change starts with thorough bench trials and ends with real plant-scale evaluation. We rely on technician and operator feedback constantly; experience has shown that small adjustments in batch size or agitation reduce formation of unwanted tars, leading to cleaner end-product and easier downstream filtration. This willingness to listen to every level of the production staff shows in final product consistency.

    Sustainability and Regulatory Considerations

    Increasing environmental scrutiny brings challenges and opportunities. As the primary source of this chemical for several major processors, we have a direct responsibility to minimize the potential impact of brominated organic compounds. To that end, we invest in vapor recovery and closed-system handling from raw material receipt all the way to finished goods packaging. Hypobromous fumes and volatile organic emissions do not get shrugged off; line supervisors check for leaks and system integrity as part of the daily routine, and we’ve found this directly reduces both environmental footprint and rework.

    For broader compliance, we track international and domestic regulations, including requirements for trace impurities like dioxins or unwanted residuals. Some of our customers supply global multinationals, and their compliance teams rely on our facility audits and testing regimes to check off substance registrations and declarations. While some suppliers treat documentation as an afterthought, our own team pulls plant data directly into customer reports, giving auditors and QC teams confidence.

    Best Practices Learned from Years of Real Production

    Every batch brings new data. Failures and unexpected test results have taught us as much as our successes. Typical best practices include detailed batch traceability, hands-on operator training, and continuing collaboration with raw material suppliers. For 3-Bromo-2,2-Bis(Bromomethyl)Propanol in particular, we have become direct advocates for robust tank cleaning protocols and active monitoring of bromine source quality—a lesson learned from several near-misses where offgrade input nearly derailed an entire production run.

    Another daily discipline involves storage and logistics. We store this product in sealed, inert-lined drums and check for signs of moisture ingress or packaging degradation before releasing any lot. This attention to practical storage not only protects our product, it also saves customers headaches down the line and keeps returns to a minimum. Our warehouse and shipping teams run final visual inspections that spot problems automated sensors sometimes miss. These practices, drilled into each shift and updated by feedback, form the backbone of our real-world commitment to reliability.

    Field Applications: Direct Impact Observed

    Much of our knowledge stems from what happens after our product leaves the gate. We track how users in the plastics processing, flame retardance, and fine chemical synthesis space incorporate our intermediate into their production. Factories often report back on exact performance differences, and these observations inform our process tweaks. For instance, we learned that certain additives or catalysts react differently depending on even minor impurities, and making small processing changes here produced much better color and consistency in end products.

    This feedback loop helps us serve not just chemical distribution houses, but also specialized manufacturers who build their own unique compounds on top of our product. The triple brominated structure opens the door to diverse transformations—nucleophilic substitution, oxidation, and coupling chemistry that would not be feasible with simpler, less reactive compounds. Watching these technical possibilities come to fruition, and seeing the downstream market segments that rely on our effort, gives meaning to the daily routines of our plant teams.

    Growth, Partnership, and the Road Ahead

    Our position as original manufacturer—not intermediary—puts us in a direct relationship with end-users, R&D chemists, and procurement managers. Through open-door technical discussions and transparent process sharing, we enable users to align their requirements with what the plant can achieve. As new regulations, applications, and customer needs evolve, we proactively revisit our material flows, safety protocols, and analytical coverage. Our in-house capacity for modifications and rapid scaling gives customers confidence to approach us with specialty requests, pilot orders, or unique performance specifications.

    We encourage site visits, third-party testing, and collaborative process improvement. Our primary focus remains delivering a brominated intermediate whose utility in flame retardants, pharmaceuticals, and beyond reflects the hard-won consistency of a manufacturer who owns every layer of the supply chain. End users can expect not only predictable quality, but a technical partner prepared to tackle the unexpected side by side with them on the plant floor. Driving improvement, reducing environmental impact, and upholding strict quality are not slogans for us—they are the quiet, persistent actions shaping every drum that leaves our production line.

    Conclusion: What It Means to Manufacture, Not Just Supply

    In an era dominated by resellers and trading firms, true chemical manufacturers serve as a backbone for product reliability and innovation. Years of hands-on chemical processing, process troubleshooting, and direct engagement with downstream users shape each aspect of our offering. With 3-Bromo-2,2-Bis(Bromomethyl)Propanol, this means a compound whose real-world utility and performance have been forged not just through theory, but from thousands of hours in vessel halls, labs, and consultation rooms. Whether your interest lies in advanced flame retardants for polymers or as a key intermediate for specialty synthesis, our commitment as a direct source brings a difference you can measure batch to batch, year to year.