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3-Bromo-1-Propanol

    • Product Name 3-Bromo-1-Propanol
    • Alias 3-Bromopropan-1-ol
    • Einecs 214-604-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    270786

    Chemical Name 3-Bromo-1-Propanol
    Cas Number 627-18-9
    Molecular Formula C3H7BrO
    Molecular Weight 138.99
    Appearance Colorless to pale yellow liquid
    Density 1.587 g/mL at 25°C
    Boiling Point 175-177°C
    Melting Point -47°C
    Refractive Index 1.4757 at 20°C
    Flash Point 81°C
    Solubility In Water Soluble
    Pubchem Cid 12272

    As an accredited 3-Bromo-1-Propanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 250 mL of 3-Bromo-1-Propanol, sealed with a screw cap, labeled with hazard and handling information.
    Shipping 3-Bromo-1-Propanol is shipped in tightly sealed containers made of compatible materials to prevent leaks and contamination. It is classified as a hazardous material and transported following regulations for flammable and corrosive substances. Proper labeling, documentation, and storage away from heat, sparks, and incompatible chemicals are strictly observed during shipping.
    Storage 3-Bromo-1-propanol should be stored in a tightly sealed container, away from heat and direct sunlight, in a cool, dry, and well-ventilated area. Keep it separate from oxidizing agents, acids, bases, and strong reducing agents. Ensure proper labeling and avoid sources of ignition. Use secondary containment to prevent leaks or spills and follow all relevant chemical safety regulations.
    Application of 3-Bromo-1-Propanol

    Applications of 3-Bromo-1-Propanol in Industrial Manufacturing

    As a direct manufacturer, we supply 3-Bromo-1-Propanol to a diverse range of industrial sectors. Below, we detail the specific industrial applications, compliance standards, process integration points, recommended ratios, and typical downstream products relevant to each sector where this intermediate plays a vital role in synthesis and production workflows.

    1. Pharmaceutical Intermediate Synthesis

    3-Bromo-1-Propanol sees critical use as a building block in the synthesis of various pharmaceutical APIs and specialty drug substances, especially in manufacturing beta-blockers and other nitrogen-containing heterocyclic compounds. Our material supports controlled halogenation and alkylation steps, especially for active pharmaceuticals that require a precise carbon chain anchoring. Downstream pharmaceutical producers consistently demand high purity for compliance with stringent regulatory and pharmacopoeial standards.

    Industry compliance standards

    • U.S. FDA cGMP (21 CFR Parts 210 & 211)
    • ICH Q7 Good Manufacturing Practice Guide
    • European Pharmacopoeia (Ph. Eur.) monographs
    • Chinese Pharmacopoeia quality standards

    Typical usage ratio

    • 0.8 to 1.05 molar equivalents relative to nucleophilic agent depending on API route; adjusted by product yield, reactivity, and by-product management.

    Downstream process integration

    • Alkylation or halogenation in the early synthetic step
    • Intermediate for introduction of 3-hydroxypropyl side chains
    • Applied under inert atmosphere in jacketed glass-lined reactors
    • Followed by extraction, purification, and downstream isolation of active intermediate

    Final product types

    • Beta-blockers (e.g., propranolol intermediates)
    • Antiviral molecules with nitrogenated side chains
    • Specialty antihypertensive compounds

    2. Agrochemical Active Ingredients Manufacturing

    Large-scale agrochemical production uses 3-Bromo-1-Propanol as an intermediate for the functionalization of active ingredients and precursor synthesis. Chemical manufacturers value it for constructing propanol-derived linkers in herbicides and fungicides, enhancing molecular activity and stability. Batch sizes range from kilogram pilot to multi-ton industrial production, adhering to environmental and product-specific standards.

    Industry compliance standards

    • FAO/WHO Specifications for Pesticides (JMPS)
    • ISO 9001:2015 Quality Management System
    • Environment, Health, and Safety (EHS) Regulation (REACH compliance in EU)
    • U.S. EPA Pesticide Registration Requirements (40 CFR Part 158)

    Typical usage ratio

    • 0.6 to 1.3 molar equivalents, with adjustments based on target molecule structure, reactivity with core pyrazole or triazole rings, and presence of secondary functional groups.

    Downstream process integration

    • Hybridization with heterocycle cores via nucleophilic substitution
    • Process step typically occurs before methylation or ring-closing reactions
    • Integration in reaction sequences for final formulation of active ingredient
    • Solvent selection and pH control critical for product safety and yield

    Final product types

    • Herbicide intermediates (e.g., 1,3-propanol-based derivatives)
    • Triazole-based fungicides
    • Plant growth regulators using hydroxypropyl building blocks

    3. Surfactant and Functional Polymer Synthesis

    Manufacturers of specialty surfactants, amphoteric agents, and functionalized polymers incorporate 3-Bromo-1-Propanol in the production of modified polyethers and block copolymers. Its primary hydroxyl group and bromine leaving group allow precise chain extension, modification, or end-capping for targeted surface activity. This functionality is essential in high-value applications such as textile auxiliaries, oilfield chemicals, and high-performance coatings.

    Industry compliance standards

    • ISO 14001 Environmental Management
    • REACH (EC No 1907/2006) registration for monomer/intermediate use
    • ASTM D4287 (Polymer manufacturing QC standards)
    • Analysis per OECD chemical safety guidelines

    Typical usage ratio

    • 0.03 to 0.12 parts by weight per 1 part monomer in surfactant copolymerization; adjusted for target molecular weight and hydrophilic-lipophilic balance (HLB)

    Downstream process integration

    • Introduced post-initiation in radical or ionic polymerization
    • Chain transfer or modification reactions for specific polymer end groups or side chains
    • Mixing under temperature-controlled conditions for consistent molecular weight distribution
    • Integrated in pilot and continuous production setups

    Final product types

    • Alkyl or hydroxypropyl functional surfactants (emulsifiers, dispersants)
    • Polyether-based demulsifiers for oil-water treatment
    • Functional block copolymers for coatings and adhesives

    4. Epoxy Resin Curing Agent Preparation

    Within the specialty chemical field, manufacturers utilize 3-Bromo-1-Propanol to introduce reactive hydroxyalkyl groups into amine or thiol curing agents for advanced epoxy resin formulations. This process improves flexibility, adhesive properties, and specific end-use performance across electronics, automotive, and civil engineering composites, requiring precise feedstock management and regulatory adherence.

    Industry compliance standards

    • RoHS Directive 2011/65/EU (for electronics/automotive)
    • ISO 9001:2015 Quality Control
    • UL 94 Flammability Standard for Insulating Materials
    • REACH compliance for handling raw intermediates

    Typical usage ratio

    • 0.1 to 0.25 molar equivalents per mole of amine curing agent; proportion varies by desired final resin network structure and glass transition temperature

    Downstream process integration

    • Added at pre-polymer modification stage
    • Enables functionalization of amine/thiol reactive sites before formulation with epoxide resins
    • Typical operations in batch reactors with real-time spectral monitoring for conversion tracking
    • Downstream blending and degassing prior to final packaging

    Final product types

    • Epoxy curing agents for adhesives and sealants
    • Structural composite matrices
    • Insulating encapsulants for electronics manufacturing

    5. Organic Electronic Material Precursor

    Producers of organic electronic materials employ 3-Bromo-1-Propanol during the synthesis of electron-transporting and hole-blocking layers for OLEDs and photovoltaic applications. The compound’s functional groups facilitate the preparation of custom aryl-alkyl or alkoxy-functional precursors used in thin-film deposition, supporting product safety, purity, and process control as required by high-end optoelectronic manufacturing.

    Industry compliance standards

    • IEC 61249-2-21 Standard for electronic raw materials
    • JPCA-ES-01 (Japan Printed Circuit Association guidelines for functional layer materials)
    • RoHS exemption reference for specialty electronic compounds
    • REACH intermediate registration for electronic sector

    Typical usage ratio

    • 0.2–0.5 molar equivalents relative to aromatic core unit depending on the desired side chain density and molecular weight, optimized by conductivity and film-forming tests

    Downstream process integration

    • Etherification or alkylation reactions for arene modification
    • Applied after core unit synthesis but prior to end-group functionalization
    • Reaction temperature and washing procedures fine-tuned to avoid unwanted byproducts
    • Purified intermediates further processed for deposition or ink formulation

    Final product types

    • Electron-transport and hole-blocking materials for OLED displays
    • Polymeric and small-molecule layers in organic solar cells
    • Functional coatings for printed circuit boards and flexible electronics
    Free Quote

    Competitive 3-Bromo-1-Propanol prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 3-Bromo-1-Propanol: Insights from the Manufacturer

    Our Hands-On Experience with 3-Bromo-1-Propanol

    In our daily work on the production line and in the lab, we’ve seen countless chemicals move through our tanks. Among this league, 3-Bromo-1-Propanol holds a respected place. Any operator or technician with experience preparing halogenated alcohols knows that every batch brings little lessons in chemistry’s stubborn ways. What sets this compound apart isn’t just its clean synthesis or purity — it’s what researchers, formulation experts, and chemists achieve after taking delivery in their own projects. This makes our perspective as a manufacturer valuable — we adjust every synthesis run based on a blend of hands-on handling and feedback from labs across the world.

    Model, Purity, and Form Offered from Our Plant

    We focus on manufacturing 3-Bromo-1-Propanol to specifications that fit modern research standards. Most customers know this chemical simply as 1-hydroxy-3-bromopropane. Sales teams sometimes throw around terms like “reagent grade,” but to us the real value appears on a chromatogram — after distillation, careful washing, and analytical checks. When clients order from our line, they receive material that meets a minimum of 98% purity, verified by GC analysis. In practical terms, chemists find this lets them run cleaner reactions, achieve sharper yields, and minimize leftover contaminants.

    We package and ship the product exclusively as a clear, colorless to slightly yellow liquid — never crystalline solids, never slurries. The density, water solubility, and boiling point all stay within known bounds, batch after batch, proven by regular lab records. What we don’t do is push 3-Bromo-1-Propanol as a one-size-fits-all solution or dress up routine numbers in marketing language. Real reliability for end-users starts from knowing exactly what is inside a drum — nothing added, nothing missing.

    How 3-Bromo-1-Propanol Shows Its Value in Chemical Synthesis

    Operators on the factory floor get to see an often-overlooked side of 3-Bromo-1-Propanol: its behavior during process scale-up and downstream handling. In our experience, this compound works exceptionally well as an intermediate for both smaller research labs and semi-commercial synthesis plants. Its three-carbon chain, bromo group at one end, and hydroxyl group at the other unlock a blend of reactivity. Unlike simple bromoalkanes, this compound provides a dual handle for modifications. Organic chemists use it to whip up esters, ethers, and a wide variety of coupling products.

    The hydroxyl end of the molecule transforms easily in esterification reactions, while the bromo atom allows for easy nucleophilic substitution. A practical example: medicinal chemistry teams use this building block to introduce propanol moieties into active pharmaceutical molecules. Some custom syntheses in the crop protection field adopt it for stepwise elongation of carbon chains. In practice, our clients run everything from test-tube scale reactions in startup biotech labs, to pilot runs in pharma companies seeking exploratory analogues.

    Batch quality plays a major role here. 3-Bromo-1-Propanol’s own reactivity profile makes it both an enabling tool and a potential challenge for researchers. Trace acid contamination or higher bromide impurities upset selectivity in downstream reactions. Through trial, error, and dozens of customer conversations over years, we’ve learned to control both headspace and tank cleanliness. As a result, our facility consistently provides material that behaves predictably whether used for nucleophilic ring openings, substituted ether synthesis, or complex coupling chemistry.

    Comparing 3-Bromo-1-Propanol with Other Halogenated Alcohols

    Many buyers ask us why choose 3-Bromo-1-Propanol over similar compounds. The answer usually starts on a whiteboard where chemists sketch out synthetic routes, mapping sources of carbon, types of leaving groups, and the ease of functional group conversions. Some laboratories turn to 1-Bromo-2-propanol, 2-Bromoethanol, or longer-chain alcohols, expecting similar reactivity. The truth is, each variant slots into niche applications — but no other substitute carries quite the same combination of ease of handling, manageable volatility, and selective transformation that this compound provides.

    Compared to 2-Bromoethanol, for instance, our product provides an extra carbon, spacing functional groups farther apart. This subtle difference grants better access for further modification — an advantage in the hands of a skilled organic chemist aiming for more extended intermediates. On the other hand, using a longer bromoalkanol, such as 4-bromobutanol, often leads to sluggishness in substitution reactions and a higher likelihood of unwanted byproducts.

    From the manufacturing standpoint, purity issues multiply as the carbon chain lengthens. In our experience, controlling bromide content, residual solvent, and trace halogenated side-products grows progressively more challenging. By staying with three carbons, users gain a practical balance between reactivity and process simplicity. That shows up on the lab bench as fewer purification cycles. Our technical team often fields questions about differences in odour, storage stability, and chemical shelf-life among halogenated alcohols. 3-Bromo-1-Propanol strikes a sweet spot: it stores with less risk of spontaneous decomposition than some brominated ethanols, with a boiling point that supports both distillation-based refinement and easy solvent handling in the lab.

    Safety officers in client companies rely on consistency from their chemical suppliers. 3-Bromo-1-Propanol, produced without mixed-halogen contaminants or ambiguous tarring, supports their needs more reliably than blends sold by general resellers or compounds docked at far lower purity. Several years ago, we aligned our process control measures specifically for this product based on end-user safety feedback. Engineers noted fewer vapor-release incidents, and laboratory workers see less variance between delivered batches. Stability over time matters — especially when research depends on reliable intermediate performance.

    Why We Focus on Controlled Synthesis and Quality Monitoring

    Every drum, bottle, and tank we fill represents months of work in improving synthesis lines. Our technical staff track more than paperwork — we read raw data, tune reactors, and manually inspect key intermediates during the run-up to every batch of 3-Bromo-1-Propanol. Chemical manufacturing is both art and science; when something veers off-spec, the cause might come down to a stuck valve as often as a wayward reagent order.

    We start our process with carefully sourced precursors, free of trace elements that might catalyze unwanted side reactions. The bromination stage, a potential choke-point for color impurities and resinous byproducts, receives scrutiny from both plant operators and QA staff. Years of hands-on practice taught us how reaction temperature and mixing rates alter the distribution of side-products. It comes down to countless small details — like knowing the correct wash sequence to minimize halide salts, or the right column size for fractional distillation at commercial scale.

    Customers often ask us about environmental stewardship. 3-Bromo-1-Propanol isn’t a consumer product, but we know full well where the responsibility to minimize waste and emissions lies. We treat brominated wastewater on-site and recycle solvents whenever possible. Not every operation can say that with honesty. By investing in both online process analysis and old-fashioned bench testing, our team is able to provide both traceable quality data and supply stability.

    Product Handling Stories from the Floor

    Every shift at our facility generates new stories about 3-Bromo-1-Propanol’s behavior — some satisfying, some educational. During transfer, the operator sees right away how the liquid’s viscosity and low color make for an easy visual check. There’s an obvious difference from higher molecular weight bromoalcohols, which often pour slower or pick up off-colors on storage.

    Laboratory staff, when prepping a fresh batch for use or QC sampling, comment on the compound’s pleasant lack of excessive odor. This is not the nose-biting effect found in shorter-chain analogues like 2-Bromoethanol. Maintenance teams, tasked with checking pressure seals and vapors during unloading, report that the product remains well-behaved, with very little fuming if stored correctly. The feedback we rely on goes beyond regulatory filings — our process improvement team values these operator notes, and we act on them whenever an opportunity to smooth handling or reduce environmental risks appears.

    There was a year early in our production ramp-up when a minor modification to the bromination stage reduced the yield of unwanted side-products dramatically. The result? Fewer filter media changes, clearer distillate, and a much easier blending process. This hands-on tinkering, born of direct feedback from tank operators and supervisors, now sits at the foundation of our quality process.

    Supporting Research and Scaling Synthesis

    Chemical researchers building new compounds or scaling up syntheses trust 3-Bromo-1-Propanol for its reactivity and predictability. We’ve delivered to hundreds of labs that use this compound in their search for better pharmaceuticals, advanced materials, and even agricultural chemicals. The recurring message from these partners remains clear: a consistently pure, well-characterized 3-Bromo-1-Propanol opens doors to new reaction pathways.

    Low levels of side impurities have an outsized effect on scaling up a process. In pilot plant work, even a hint of over-brominated material stalls reactions and throws off isolation yields. Our experience as a manufacturer supports the needs not just for high purity but day-to-day batch reliability. Every synthesized lot is certified via in-house methods, but our technical group also collaborates with clients who require additional validation or unique application-driven batch customizations. Personal contact between our lab team and client chemists smooths the feedback loop, allowing us to tweak certain parameters, troubleshoot unexpected behavior, or advise on storage and handling.

    Environmental Responsibility in Halogenated Alcohol Production

    Producing halogenated chemicals brings with it weighty environmental and safety responsibilities. Our process improvements are not just about efficiency or cost savings. From an environmental perspective, each runoff stream or vented tank must meet current regulatory targets for bromine release. Wastewater generated during manufacturing undergoes treatment for halide removal before final discharge. In parallel, our solvent recovery systems capture major process solvents, reducing both emissions and the volume of fresh solvent required over time.

    One of the learnings our company took to heart early: the by-products from 3-Bromo-1-Propanol manufacturing can have a lingering impact unless addressed rapidly. This moved us to finalize investments in in-house treatment facilities years before most regional regulations made them mandatory. Every drop of spent acid or residual organic phase receives proper handling. When improvements or new waste treatment steps appear in the academic literature, our technical group runs small-scale pilots to check their real-world impact in our setup.

    Beyond our gates, we work closely with logistics partners and customers to support downstream safety. Proper drum labeling, freezer-compatible packaging, and clear stability data integrate our product into responsible chemical use chains. Through these steps, we feel a direct connection between our role as manufacturer and the broader field of environmental stewardship in chemical science.

    Lessons from Market Feedback and Customer Partnerships

    Our approach to 3-Bromo-1-Propanol has been shaped by years of back-and-forth with end-users, not just from an internal lab perspective. Shortly after we started regular shipments, feedback from a crop science research team highlighted the need for finer particle filtration in the final liquid product. Minute adjustments in filtration led to easier downstream purification on their end, a direct customer-driven improvement. Another story comes from a pharmaceutical synthesis group who reported greater stability in long-term storage than they anticipated, due to purity upgrades we introduced as part of a broader process overhaul.

    Repeatedly, collaborative efforts between our team and users have clarified not only technical specifications but also packaging and dispensing practices. For university and R&D staff, we provide smaller bulk sizes packaged under nitrogen headspace for longer shelf-life, avoiding the frustration of oxidized stocks facing researchers in slower-moving projects.

    We listen carefully to requests for documentation supporting material traceability, and we remain ready to supply impurity profiles when needed. The relationship helps both sides — insights from university researchers and process chemists enable us to predict shifts in usage patterns, from target molecules in early drug discovery to new environmental chemistry research.

    Responding to Industry Trends

    In recent years, the demand profile for 3-Bromo-1-Propanol has shifted. Where the majority of requests once arose from classical organic synthesis shops, multiple industries now access this compound for both established and new synthetic approaches. We keep our ears to the ground, staying informed about both advances in halogenated chemistry and regulatory updates that might impact the transport, storage, or future use of brominated intermediates.

    Regulatory reform and tightening import controls have placed real strain on generic suppliers with less robust documentation or traceable quality systems. As a direct manufacturer, our ability to vouch for each batch and adjust specifications flexibly remains a strong advantage. We work, side by side with users’ compliance and safety teams, to ensure that material moving through our gates measures up, not just to our internal benchmarks but to evolving industrial best practices.

    Looking Forward: Supporting Cleaner, More Efficient Chemistry

    As the chemical industry shifts toward greener synthesis routes and more sustainable processes, our outlook for 3-Bromo-1-Propanol remains cautiously optimistic. The compound’s utility in functional group interconversion and its ready compatibility with existing synthetic toolkits set it apart from more exotic or difficult-to-handle intermediates. We respond to calls for cleaner, less wasteful chemistry by improving internal metrics: less off-spec material, less solvent used, and lower emissions per ton shipped. This cycle of feedback and improvement supports both large-scale users and researchers driving new science.

    Direct interaction with buyers, combined with a careful balance of process optimization and investment in better analytical tools, keeps us honest and grounded. We see future research in catalysis, green solvents, and bio-based synthetic targets as an opportunity for 3-Bromo-1-Propanol to support both established and next-generation chemistry. As the needs of researchers and industry partners change, so too will our practices — grounded in direct production experience, a commitment to safety, and respect for every feedback note that lands in our inbox.

    Conclusion: Honing the Craft of Halogenated Intermediate Production

    Making 3-Bromo-1-Propanol isn’t just about synthesizing another catalog item. Every liter delivered reflects hours of careful control and a long dialogue between hands-on manufacturing, technical support, and the working chemists building the next pharmaceutical, agricultural breakthrough, or advanced material. Our edge comes not from shiny language, but from attention to process, willingness to adjust, and day-by-day engagement with both the technical and human sides of chemical manufacturing.

    For those who rely on 3-Bromo-1-Propanol, quality isn’t a checkbox — it’s the starting point for better science. Our job as manufacturer: keep delivering that promise, batch after batch, guided by experience, supported by honest feedback, and anchored in practical know-how.