Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

3-Benzyloxy-4-Methoxybenzaldehyde

    • Product Name 3-Benzyloxy-4-Methoxybenzaldehyde
    • Alias 3-Benzyloxy-4-methoxybenzaldehyde is also known by the alias "4-Formyl-2-methoxyphenyl benzyl ether".
    • Einecs 629-455-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    429033

    Chemical Name 3-Benzyloxy-4-Methoxybenzaldehyde
    Molecular Formula C15H14O3
    Molecular Weight 242.27 g/mol
    Cas Number 37945-18-7
    Appearance White to off-white solid
    Melting Point 84-86°C
    Solubility Soluble in organic solvents such as ethanol, DMSO, chloroform
    Smiles COC1=CC(=CC(=C1)OCC2=CC=CC=C2)C=O
    Purity Typically >98%
    Storage Temperature 2-8°C (Refrigerated)
    Synonyms 4-Methoxy-3-(phenylmethoxy)benzaldehyde
    Odor Odorless

    As an accredited 3-Benzyloxy-4-Methoxybenzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of 3-Benzyloxy-4-Methoxybenzaldehyde, sealed with a screw cap and labeled with safety information.
    Shipping 3-Benzyloxy-4-Methoxybenzaldehyde is shipped in tightly sealed, chemical-resistant containers, protected from light, moisture, and extreme temperatures. Packaging complies with safety and regulatory standards for hazardous chemicals. Appropriate labeling and documentation ensure safe handling during transit. Shipping methods are selected to minimize transit time and risk of exposure or leakage.
    Storage **3-Benzyloxy-4-Methoxybenzaldehyde** should be stored in a tightly sealed container, protected from light and moisture, at room temperature (15–25°C). Store it in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers. Ensure proper labeling and secure storage to prevent accidental release. Use standard laboratory safety protocols for handling aromatic aldehydes.
    Application of 3-Benzyloxy-4-Methoxybenzaldehyde

    Applications of 3-Benzyloxy-4-Methoxybenzaldehyde in Industrial Manufacturing

    3-Benzyloxy-4-Methoxybenzaldehyde serves as a high-purity intermediate and building block for multiple high-value chemical industries. Our production ensures batch-to-batch consistency, supporting customers in regulated and specification-driven manufacturing sectors.

    1. Pharmaceutical Intermediate for Active Pharmaceutical Ingredients (APIs)

    This compound is widely recognized as a key intermediate in the multistep synthesis of various APIs, including selective serotonin reuptake inhibitors and specialty anti-infectives. As the aldehyde group provides a reactive handle, customers use it for the formation of complex heterocycles and as a precursor for the installation of chiral centers under cGMP conditions. Process engineers optimize its coupling or condensation steps by maintaining precise reaction parameters for maximum impurity control, directly impacting downstream crystallization and purification of actives.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guidance
    • US Pharmacopeia (USP) for intermediate specifications
    • EU EudraLex, Volume 4 cGMP for APIs
    • ISO 9001:2015 for quality management

    Typical usage ratio

    • 0.95–1.10 molar equivalents in key condensation step, adjusted for route selectivity and downstream purification recovery

    Downstream process integration

    • Enters synthesis after initial aromatic functionalization, participates in key intermediate coupling before chiral transformation or reduction

    Final product types

    • Active pharmaceutical ingredients for CNS drugs, anti-infective agents, and antihistamines

    2. Specialty Flavors and Fragrance Ingredients

    As a benzaldehyde derivative with controlled aromatic ether and methoxy functionalities, this material is adopted in specialty flavor and fragrance manufacturing by global formulators. It imparts specific floral, balsamic, and vanilla-like notes in compounded bases. Perfume chemists employ it in controlled dosages to balance stability and sensory profiles during the distillation or compounding of complex fragrances. Its purity and batch uniformity are critical in large-scale blending to meet sensory and shelf-life specifications for fine fragrance and flavor house customers.

    Industry compliance standards

    • IFRA (International Fragrance Association) Standards
    • FCC (Food Chemicals Codex) for technical grades
    • ISO 9235: Aromatic natural raw materials guidance
    • EU Regulation (EC) No 1334/2008 on flavorings

    Typical usage ratio

    • 0.1–1.5% by weight for concentrate blending, scaled according to end product compliance and odor threshold

    Downstream process integration

    • Blended post-synthesis of primary fragrance core, incorporated during cold compounding or oil solubilization, followed by filtration and QC sensory evaluation

    Final product types

    • Fine perfumes, luxury candles, flavor syrups for confectionery, and compound flavor bases for beverages

    3. Advanced Materials for Organic Electronics Synthesis

    R&D teams and electronic materials manufacturers utilize this compound as a precursor in the synthesis of functionally substituted aromatic monomers for organic light-emitting diodes (OLEDs) and organic conductive polymers. Controlled reactivity of the aldehyde group in metal-catalyzed cross-coupling reactions allows for the selective formation of tailored molecular backbones. Product consistency and impurity profile remain crucial for electronic film yield and device performance, guiding internal process validation and material qualification.

    Industry compliance standards

    • RoHS Directive (EU) 2015/863—Restriction of hazardous substances
    • IEC 62474 Reportable substances for electrical/electronic products
    • ISO 9001 for traceability and batch recordkeeping

    Typical usage ratio

    • 1.0 equivalent as monomer precursor; loading levels optimized during laboratory scale-up and final compositional adjustment of electronic substrates

    Downstream process integration

    • First charged to reactor in monomer synthesis, then isolated and coupled via Suzuki or Heck-type reactions for final electronic material fabrication

    Final product types

    • OLED emitter layers, photoactive thin films, and organic conductive polymer resins

    4. Agrochemical Building Block in Fungicide Synthesis

    Agricultural chemistry manufacturers apply this synthetic aromatic aldehyde to construct bioactive heterocycles in selective fungicide and herbicide products. It introduces key aromatic functionality in multi-step synthetic schemes where process flow requires high-purity handling, low metal residue, and reproducible reactivity to meet environmental and safety registrations. The ability to withstand strong basic and acidic conditions during downstream cyclization and condensation chemistry ensures robust yields and consistent performance of technical-grade actives.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • REACH Regulation (EC) No 1907/2006 for chemical safety
    • ISO 17025: laboratory testing accreditation for QC

    Typical usage ratio

    • 0.80–1.20 molar equivalents relative to active center, adjusted to optimize yield, minimize byproduct, and meet downstream impurity limits

    Downstream process integration

    • Charged after initial amide or thioester preparation, subjected to condensation and heterocyclization under controlled reflux and pH conditions

    Final product types

    • Technical fungicide concentrates, granules, and liquid herbicide formulations used for crop protection
    Free Quote

    Competitive 3-Benzyloxy-4-Methoxybenzaldehyde prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    3-Benzyloxy-4-Methoxybenzaldehyde: Reliable Ingredient by Direct Manufacturer

    Introduction to Our Manufacturing Practices

    Our commitment to the field of specialty organic synthesis started decades ago, back when quality and reliability meant getting your hands stained alongside your products. Working from the ground up, we’ve come to understand every detail in the process of crafting 3-Benzyloxy-4-Methoxybenzaldehyde, from sourcing high-purity starting materials to managing the final crystallization. This compound, with CAS number 51848-23-8, represents more than another entry in a catalog. It’s the result of a production culture grounded in careful monitoring, experienced hands, and dedication to the needs of fine chemical industries.

    How We Approach Purity and Quality Control

    Every batch we make passes through our own strict quality checkpoints. Over the years, we’ve learned that purity isn’t a bonus—it’s the entire point of the effort. With 3-Benzyloxy-4-Methoxybenzaldehyde, the smallest impurities can end up causing cascading failures in downstream chemical transformations, especially in pharmaceutical intermediate synthesis and advanced material design projects.

    Our production lines rely on freshly distilled reagents and a series of recrystallization steps, matched to each lot’s profile. Instead of relying wholly on off-the-shelf analytical data, we monitor every synthesis step with a full suite of in-house instruments (HPLC, GC/MS, NMR, FTIR). Many of our chemists have stood at the same bench for years, not just running machines but interpreting spectra, catching the hints that only experienced eyes can see when something’s off. This vigilance pays off, especially when a client’s next synthesis hinges on subtle variations in the aldehyde function or when ether protection must remain intact and isolated.

    Product Insights: 3-Benzyloxy-4-Methoxybenzaldehyde

    This aromatic aldehyde, featuring a benzyloxy group at position three and a methoxy group at four, has found a place in countless synthetic pathways. Its structure (C15H14O3, mol. wt. 242.27) bridges the gap between rigid scaffolding and reactivity, making it a favorite among research scientists and production chemists alike. For people outside the synthesis lab, the difference between 3-Benzyloxy-4-Methoxybenzaldehyde and similar benzaldehydes may seem academic, but years of hands-on use have demonstrated otherwise. The position of those substituents can make or break a project’s route efficiency.

    In contrast with its isomers or substituted analogs (like 2-benzyloxy derivatives, or simple vanillin), this compound’s electron-donating properties and steric influences open up distinct reactivity channels. By shielding the aldehyde function with carefully chosen protecting groups during multi-step syntheses, we’ve seen researchers boost yields and cut down side-product formation. Our product’s stability under storage and resistance to undesired oxidation both trace back to the original choices we made in tweaking the purification process years ago.

    Meeting the Expectations of Scientists and Engineers

    Advertising specs and quoting numbers can hardly express the real reason most chemists come back for this particular compound: dependability. In every shipment, we aim to deliver a consistent melting point (usually 97–100°C, depending on trace solvent), a single sharp HPLC peak (area percent greater than 99), and a minimal UV-Vis background. We keep a close dialogue with formulation teams demanding volumes from grams to multi-kilo lots, because every end-use—from organic electronics to medicinal chemistry—demands a slightly different grade. We don’t just shovel powders into drums; we manage lot-by-lot adjustments and supply authenticated reference samples, with no shortcuts.

    Usage: Broad Applications, Specific Demands

    Over the years, we’ve watched 3-Benzyloxy-4-Methoxybenzaldehyde work its way from a research novelty to a central ingredient in pilot plants and industrial R&D. Most commonly, universities and industrial labs select it for complex molecule assembly, where the benzyloxy group gives them a versatile handle for further modifications. In many syntheses, this compound acts as a masked catechol or as a precursor for various heterocycles where selective deprotection matters. A few partners employ it as a key intermediate in active pharmaceutical ingredient (API) synthesis, where failure in a scale-up could mean the loss of an entire trial batch. Our consistent supply and purity minimize the headaches and financial loss associated with failed reactions.

    Material scientists often use derivatives of our product while targeting novel photoactive compounds. In the hands of skilled synthetic chemists, the combination of the electron-rich methoxy group and the benzyloxy protection leads to efficient cross-couplings and regioselective transformations. On more than one occasion, a bit of consultation with a process engineer has sent a customer’s process yield soaring, just by tweaking protecting group removal or solvent polarity. Sharing these lessons makes our job more rewarding—and our partners’ projects more successful.

    Weighing the Real Differences from Lookalike Compounds

    If you’ve had the chance to compare product performance over time, you already know that not every aromatic aldehyde is cut from the same cloth. 3-Benzyloxy-4-Methoxybenzaldehyde’s closest alternatives—4-benzyloxybenzaldehyde, 3-methoxybenzaldehyde, or even unsubstituted parent benzaldehyde—fall short in certain synthetic tasks. The location of the benzyloxy and methoxy groups, combined with their synergy, drives a substantial shift in reactivity profiles.

    Our product’s higher solubility in organic solvents, coupled with predictable electrophilic/nucleophilic balance, gives process chemists fine control over reaction outcomes. Impurity levels in similar products from traders often risk sabotaging yields at scale. We’ve tested competitor samples side by side, watching unwanted peaks creep up during NMR scans or sticking on chromatographic columns. Our in-house product shows reliably clean spectra, sharper melting transitions, and longer shelf stability—attributes that set apart a bench-quality intermediate from an industrial solution.

    Decades spent listening to feedback from formulation chemists helped us refine not just synthesis, but also packaging and shipment protocols. Moisture uptake during transport, exposure to UV during storage, and trace solvent retention used to cause headaches for long-term users. Over time, we solved these issues through packaging upgrades, batch-specific drying procedures, and integrating real-time logistics tracking, minimizing the chance that a kilo’s worth of sensitive aldehyde gets compromised before it even reaches your loading dock. These non-obvious tweaks often separate a true manufacturer from a middleman repackager.

    Behind the Scenes: Analytical Verification

    Our analytical department traces every lot to a certificate of analysis bearing our chemists’ actual signatures, not just rubber-stamped checkboxes. Every test spectrum, from proton and carbon-13 NMR to high-resolution mass spec, is available for client inspection. This transparency developed slowly—born from collaborations with regulatory officers and research partners who pressed for defensible documentation long before “data integrity” became a buzzword in the industry. We retain reference samples of every lot, keeping them archived for follow-up analyses if needed. On more than one occasion, this protocol has helped a returning customer trace back a scale-up issue to their own process environment, clearing doubts about intermediate quality without delay.

    We welcome direct dialogue with R&D chemists and procurement specialists who insist on double-checking batch data. Our attitude is: challenge us, test us, and demand evidence. In large-scale projects, waiting for replacement material can spell disaster—so our focus remains on getting the answers, and the product, into your hands without bureaucratic detours.

    Packaging and Delivery: Real-world Challenges, Real-world Fixes

    Working directly with specialty logistics carriers over the years taught us that customs and packaging obstacles can shut down even the most reliable supply. Sensitive aldehyde intermediates like 3-Benzyloxy-4-Methoxybenzaldehyde don’t travel safely in just any drum or bottle. Early on, we grappled with soft seals, leaching from plastics, or mild oxidation during months-long sea shipments. Over time, we invested in lined, UV-proof containers, inert atmosphere filling, and tailored pack sizes ranging from a few grams for research up to bulk volumes for industrial campaigns. Each packaging milestone followed not just from regulatory guidelines, but from actual failure scenarios we’ve encountered with clients.

    Our operations team tracks every outgoing shipment, sharing real-time updates that allow purchasing managers to plan their downstream workflows. Delayed customs clearance or regulatory holdups aren’t just red tape for us—they’re downtime for our partners, and we’ve built contingency plans with backup inventory in key regions to keep that risk down. In a market prone to ever-changing tariffs or shifts in shipping lanes, these logistical habits form the backbone of dependable chemical supply.

    Looking Ahead: Sustainability and Responsible Manufacturing

    Supplying specialty aldehydes at scale used to mean large waste streams and frequent renewals of hazardous reagents. As we scaled our processes to meet industrial demand, we committed to streamlining our solvent recovery and recycling protocols. Today, our facility features a closed-loop system for most organic solvents, including those used in the production of 3-Benzyloxy-4-Methoxybenzaldehyde.

    We switched to greener alternatives in every stage where existing chemistry allowed, and reengineered distillation setups to decrease emissions and minimize operator exposure. Technically, these improvements sometimes run up our production costs, but the long-term relationships built on trust matter more than squeezing out short-term gains. We’ve worked through industry workshops, audits, and third-party environmental monitoring over the years, not waiting for regulation to nudge us forward.

    We regularly solicit feedback from user labs on reuse of shipping containers, reduction of secondary waste, and compatibility with their own green chemistry initiatives. This dialogue has led to several improvements in product format, including easier-to-weigh low-dust granules and solvent-wet formats for process integration. Building environmental responsibility into innovation, rather than tacking it on at the end, keeps us competitive and keeps your lab in line with the latest sustainability expectations.

    Real Stories, Real Solutions

    Relationships with our clients, whether multinational pharmaceutical firms or single-investigator university labs, hinge on problem-solving rather than catalog sales. Several years back, a contract manufacturer reached out over a persistent yield issue in a photochemical step that used our 3-Benzyloxy-4-Methoxybenzaldehyde. Their team had cycled through half a dozen vendors; only after we reviewed shipment logs and batch data did we pinpoint micro-level peroxide contamination left over from transfer lines at another vendor. Removing that point of contact boosted their project success rate and cemented a long-term partnership.

    Another example comes from an EU-based material science team developing OLED prototypes. Early pilot runs exposed slight yellowing in finished devices, traced back to minor impurities in benzaldehyde intermediates. Using our expanded purification suite, we collaborated directly with their analysts, producing an ultra-high-purity, photo-stable batch that finally unlocked their required device lifetime specs. Everyday stories like these drive innovation not just in the lab but along the entire supply chain—from sourcing to shipping—grounded in solving real, costly problems.

    Connecting the Chemical Supply Chain, One Partnership at a Time

    No automated ordering system or list of certifications can replace direct, knowledgeable consultation between actual manufacturers and their customers. In every kilogram of 3-Benzyloxy-4-Methoxybenzaldehyde we ship, there’s an embedded record of technical insight, manufacturing grit, and long-term trust. As markets and regulatory standards shift, we commit to continuous improvement—not just in our products, but in the transparency, responsiveness, and reliability our partners expect.

    We pay close attention to the feedback cycle, running on-the-fly impurity screens when clients develop new synthetic applications and updating reference documentation based on evolving end-use specifications. Our teams regularly meet with collaborators for technical Q&A, offering guidance on choosing reaction conditions or storage strategies that preserve the product’s performance start to finish.

    What to Expect from Us

    Customers working with us for the first time notice the difference in flexibility and the transparency available in every conversation. Instead of generic service scripts, they receive direct answers to their batch-level questions, troubleshooting tips from process chemists who have worked through the same challenges, and realistic delivery forecasts supported by robust logistics planning. Rather than promising impossible lead times, we communicate proactively about raw material scarcities or shipping irregularities.

    We keep rigorous records of every suggestion and complaint, using those data points to further fine-tune everything from raw material pre-treatment to final product packaging. Our whole operation depends on telling the whole story: not just what makes our product different, but why those differences matter in the context of your project timeline, regulatory review, or product innovation cycle.

    Commitment to True Partnership

    We built our company on the belief that genuine value comes from honest work and deep technical engagement—not just throughput or price point. 3-Benzyloxy-4-Methoxybenzaldehyde, as manufactured here, stands as a testament to the lessons learned across countless successful and failed experiments, regulatory audits, and on-the-ground feedback loops.

    No two labs will use this material in the exact same way. By maintaining open lines for technical collaboration, fast and traceable deliveries, and unwavering focus on lot integrity, we support customers facing ever-rising standards in product quality and compliance. Rather than chasing every new market trend, we refine what works at the bench, in the process bay, and under the auditor’s microscope.

    For those who recognize the irreplaceable value of direct manufacturing knowledge and consistent product quality, our work on 3-Benzyloxy-4-Methoxybenzaldehyde remains as relevant as ever—backed by a team ready to tackle tomorrow’s challenges with today’s experience.