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HS Code |
437170 |
| Chemical Name | 3-Amino-4-Methylphenol |
| Cas Number | 2835-99-6 |
| Molecular Formula | C7H9NO |
| Molecular Weight | 123.15 g/mol |
| Appearance | Off-white to beige powder |
| Melting Point | 102-106°C |
| Solubility | Soluble in water and alcohol |
| Density | 1.17 g/cm³ |
| Pka | 9.71 |
| Synonyms | 2-Hydroxy-5-methylaniline |
| Structure | Benzene ring with amino group at position 3 and methyl group at position 4 |
As an accredited 3-Amino-4-Methylphenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 100g package of 3-Amino-4-Methylphenol comes in a sealed amber glass bottle with a secure, chemical-resistant screw cap. |
| Shipping | Shipping for 3-Amino-4-Methylphenol should comply with relevant chemical regulations. The product is typically packaged in tightly sealed containers, protected from moisture, heat, and incompatible substances. Proper labeling, documentation, and transport in accordance with local, national, and international hazardous material guidelines ensure secure and safe delivery. |
| Storage | 3-Amino-4-Methylphenol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers and acids. Protect from light and moisture. Store at room temperature and avoid sources of ignition. Ensure proper labeling, and follow all local regulations and safety guidelines for chemical storage. |
Applications of 3-Amino-4-Methylphenol in Industrial Manufacturing3-Amino-4-Methylphenol is a specialty chemical intermediate manufactured for demanding industrial segments. Its unique aminophenol structure enables selective functionalization in synthesis and surface chemistry. Below are industrial application routes where this raw material is integrated for downstream high-value production. 1. Hair Dye Formulation for Cosmetics SectorColorant manufacturers utilize 3-Amino-4-Methylphenol as a coupler component in oxidative hair dye products. Formulators depend on its aminophenolic functionality for stable color shade development, especially in brown, mahogany, and chestnut tone systems. Our plant delivers product meeting direct pigment and oxidation dye requirements, addressing regulatory testing for salon and retail chain distribution. As an essential intermediate, it reacts with oxidizing agents and primary intermediates to generate durable chromatic shades after precise blending and quality control, ensuring batch-to-batch consistency for mass-market hair colorants. Industry compliance standards
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2. Intermediate for Pharmaceutical API SynthesisProcess chemists employ 3-Amino-4-Methylphenol as a structurally specific intermediate in several Active Pharmaceutical Ingredient (API) synthetic routes, particularly for paracetamol analogs and certain antipyretic agents. Controlled reaction parameters allow coupling and selective activation of the aminophenol nucleus. We provide bulk lots with pharmaceutical traceability, particle size uniformity, and impurity control in alignment with GMP auditing, essential for multi-step synthesis leading to final drug substances. Industry compliance standards
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3. Dye and Pigment Manufacturing for Textile FibersDye houses and pigment producers integrate 3-Amino-4-Methylphenol in azo and anthraquinone dye synthesis, particularly where amino group activation supports high affinity for protein and synthetic textile substrates. Its controlled reactivity profiles help develop bright, stable colors after sulfonation and diazotization steps, with each batch optimized for specific fiber compatibility. Rigorous quality documentation and traceability assure compliance with stringent textile safety and environmental regulations while maintaining reproducibility for global apparel and upholstery markets. Industry compliance standards
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4. Corrosion Inhibitor Synthesis for Metal Surface TreatmentManufacturers of corrosion inhibition additives use aminophenol derivatives in tailored molecular designs for metal working fluids, coolant additives, and passivation treatments. 3-Amino-4-Methylphenol’s electron-rich aromatic ring provides chelation sites and surface adsorption, supporting durable inhibitor films on ferrous and non-ferrous alloys. Our production meets purity criteria required for long-run performance, with trace metal, halogen, and organic contaminant screening for automotive, aerospace, and industrial cooling applications. Industry compliance standards
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5. Polymer Modification for Specialty Resin ProductionResin manufacturers employ 3-Amino-4-Methylphenol as a reactive modifier in custom phenolic, epoxy, and polyurethane resins. Its ortho-activated amino-phenol scaffold enables crosslinking and molecular bridge formation, imparting improved thermal stability and chemical resistance to finished polymers. We supply controlled particle size lots and guarantee low ionic contaminant profile essential for specialty resin synthesis utilized in electronics, coatings, adhesives, and composite manufacturing. Industry compliance standards
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For decades, our team at the chemical plant has worked closely with 3-Amino-4-Methylphenol and seen firsthand how its properties set it apart on the production floor and at the lab bench. This molecule, C7H9NO, has proven to be much more than a line item in a catalog to us; it’s one of the products where precise synthesis and careful handling can make a real difference in industrial outcomes. Our model, often referenced under the industry-recognized CAS number 2835-99-6, is supplied with a minimum purity of 99%. Consistency means avoiding setbacks in downstream processes, so we never take shortcuts on quality checks during crystallization and drying.
Workers in chemical manufacturing will agree: it’s one thing to synthesize a compound on paper, and another to keep every batch up to the exact same level in large-scale reactors. We’ve found that 3-Amino-4-Methylphenol benefits from a slightly slower addition of methylating agent, which helps control para-products during reaction. Years of scale-up experience have shown that a well-controlled pH throughout the amination steps reduces impurity byproducts, especially those that impact color purity.
After synthesis, drying conditions influence not just moisture content, but also powder flow for the next user. Excess moisture from hurried drying increases the clumping, which wrecks dosing accuracy, especially when formulation demands precise weights for colorants or dyes. We’ve learned to tune filtration and drying sequence based on seasonal humidity. This prevents extra time spent breaking up cakes, or worse, sending out a product with a moisture spec outside the customer’s range.
Raw material selection starts the whole process. If we compromise at this first stage—if starting aniline has inconsistent trace metals or residual solvents from an earlier run—downstream steps suffer. We monitor for off-odors and discoloration during every load-in, as these give the best early warnings of a contamination issue. The result is a pale, free-flowing powder with high assay and low heavy metals, suitable for demanding applications.
Our buyers talk about the real frustrations of variable materials. A customer from a specialty dye house once explained how source changes derailed their dye-lot batch production, leading to rework and lost revenue. By keeping our own vertical production in-house, we cut out inconsistencies in batch traceability and provide certificates based on batch runs, not estimated averages. Every new customer batch gets a fresh QC panel run, including HPLC, GC-MS, and Karl Fischer titrations, so downstream blending stays reliable.
3-Amino-4-Methylphenol sees broad use in the synthesis of many colorants and dyes, especially in hair dyes and textile pigments. It features a unique reactivity profile thanks to the combination of an amino group at the 3-position and a methyl group at the 4-position of the benzene ring. These substituents don’t just tweak the molecule; they change how it reacts compared with other aminophenols.
In hair colorant applications, for example, this product supplies a rich source of chromophore precursors. Colorists in the personal care sector select 3-Amino-4-Methylphenol for its reliable tone yield and enhanced intensity, especially in dark brown and black shades. Our experience shows that formulations designed with this compound in mind develop more stable hues over time, avoiding the instability seen with some other aminophenol isomers. In textile dyeing, users get sharp, even coloring that holds up under heat, UV exposure, and frequent washing. Our product’s high purity means less chance of side reactions, so colors stay true and repeat runs stay consistent.
Laboratory results can read similar on paper, but our manufacturing staff have spent enough years with several aminophenol variants to recognize their differences fast, particularly under real-world conditions. For example, 2-Amino-4-Methylphenol, with its amino group in a different ring position, gives a noticeably different shade base and sets much faster in oxidative dye formulations. 4-Amino-2-Methylphenol, on the other hand, while useful, often introduces more volatility in solution stability and can complicate polymerization steps.
We’ve tracked feedback from end users developing new dye formulas. Their main complaint with alternate isomers often lies in unpredictable reactivity. 3-Amino-4-Methylphenol keeps a better performance record for repeat mixing and stable tone, supporting what we see in pilot-scale validation: less fading and a sharper color endpoint. Our research team attributes this to a lower rate of side-path oxidative couplings, keeping product impurities under tighter control.
Manufacturing any aminophenol involves careful attention to protection and waste handling. We maintain closed systems during reaction and transfer, venting through active carbon traps to avoid ambient exposure to powder or vapors. Operators manage all processes from behind control panels with real-time sensors that trigger alarms before issues escalate. Proper PPE, including nitrile gloves, barrier lab jackets, and goggles, isn’t negotiable. We keep first aid stations close at hand; small exposure can irritate skin or eyes, which reminds our team never to shortcut decontamination steps.
Wastewater treatment draws as much attention as reaction chemistry. Our investment in advanced filtration and neutralization systems keeps effluents within regulatory standards, with constant sampling for trace contaminants like aniline residues. Our target is not just passing a local discharge test, but building a reputation for environmental responsibility. Outside audits always get open access to both process logs and emissions readings.
3-Amino-4-Methylphenol’s sensitivity to air and light means packaging gets close attention throughout the filling and dispatch process. We use multi-layer, sealed containers with desiccant pouches for bulk shipments, as well as food-grade inner liners for smaller volumes going to pharmaceutical and cosmetics customers. Long shelf life depends on keeping moisture and air out. We never rely on generic packaging from outside suppliers, instead designing drums and sacks to fit the storage conditions most users encounter—hot, humid regions or cooler, drier warehouses.
During hot summer months, we ramp up insulation and track transit timelines with GPS-linked data loggers; a single shipment stuck in a port in the wrong climate could lose a percentage of usable product if not caught early. We work with forwarders who understand the delicacy of specialty chemicals, not just general cargo.
Chemical manufacturing works best when it runs as a partnership. Over the years, open channels with formulation chemists, lab managers, and purchasing teams have shaped the way we monitor and adjust our processes. Direct feedback led us to change drying cycle parameters after noticing slight caking during summer deliveries to Southeast Asia. A customer’s remark about trace iron content spurred an overhaul of tank cleaning protocols, which cut cross-contamination events by over 80%.
We also run small-batch sample lots on request for customers developing new color blends or testing toxicological compatibility. These samples run through the full battery of our plant’s QC checks, allowing R&D teams outside our company to prepare for scale-up sooner and with fewer surprises. One designer of hair dye formulas pointed out that slight shifts in impurity profile could trigger changes in regulatory filings, meaning each minor improvement on our side can save end users months of paperwork.
A single specification sheet doesn’t guarantee a problem-free material every time. Rigorous in-house QC forms the backbone of how we safeguard batch-to-batch uniformity. Each production run undergoes spectral fingerprinting using advanced HPLC and GC-MS, checked against retained reference samples from prior lots. Further, we back findings with moisture analysis and colorimetric evaluation—essential for dye or pigment houses where even minor shades off target lead to entire production runs lost, not just minor corrections. When discrepancies appear, the lot never leaves our facility.
QC data, including impurity profiles and heavy metals screen, are available on request. For customers working under tight regulatory conditions, these records help with compliance, expedite safety submissions, and speed up the launch for new formulations. All results remain linked by lot code to the actual drums delivered—if a problem arises in the field, we can trace the issue back to a precise date and reactor number in minutes.
Volatility in chemical supply chains has challenged us, especially over the past decade. Global disruptions—from energy price swings to transportation breakdowns—tested our commitment to on-time delivery of 3-Amino-4-Methylphenol. We addressed this by expanding raw material sourcing pools domestically and regionally and partnered with local transporters for short-haul links between factories and ports. Building up buffer stocks in strategic warehouses proved essential; it sometimes meant sitting on costly inventory but prevented customers from having to spot-buy lower-quality substitutes when outside supplies ran short.
We protect production schedules by pre-booking utility needs and maintaining critical spares in the plant warehouse. When a key condenser failed three years ago, we had a replacement on site within a day and avoided missing a shipment. Experience taught us never to depend solely on just-in-time inventory for essential compounds like 3-Amino-4-Methylphenol—manufacturing downtime affects not just us, but everyone up and down the supply line.
The commodity market treats chemicals as swappable goods, but our years in the plant floor and QC lab prove otherwise. Each molecule has its particular set of quirks and trace behavior; for 3-Amino-4-Methylphenol, it’s the color stability under stress, the low impurity profile, and its repeat performance in end-user applications that count. Keeping production under one roof lets us control each step and respond to problems right at the source.
Hands-on involvement with batch records and real-time plant analytics flags trends before they turn into issues. Upgraded sensor tech, routine operator training, and ongoing investments in QC capability keep our production reliable while evolving with market standards and new technical requirements.
Environmental regulation grows stricter each year. We see new reporting requirements for aminophenol production waste streams and dust emissions, and our response has been to invest even more in process containment and waste treatment. Downstream users ask for tighter control over trace metals and residual solvents beyond traditional material grades. We’re piloting further purification and gas-phase analysis steps based on this direct feedback.
Sustainability concerns carry over to customers in cosmetics and textiles: they want assurance that the 3-Amino-4-Methylphenol they source comes from processes with low environmental impact and full traceability. We collaborate with raw material suppliers who operate under transparent codes of conduct and continue to seek green chemistry approaches that cut solvent and energy demand. Every kilogram recycled or saved from waste allows both us and our partners to meet sustainability goals.
Producing 3-Amino-4-Methylphenol at scale involves trade-offs and hard decisions, shaped by real-life constraints in materials, energy, and customer requirements. Our team’s ongoing investment in equipment, quality assurance, open communication, and environmental safeguarding lets us deliver a product that does more than meet a spec sheet – it consistently helps our industry partners formulate new dyes, meet compliance targets, and innovate with confidence.
Direct experience has taught us that every small detail in production, from raw material checks to packing the final drum, counts towards reliable results for our customers. Our company’s approach has always valued thorough oversight and real-world problem-solving. As applications for 3-Amino-4-Methylphenol continue to grow, so does our commitment to quality, safety, and responsible production.