Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

3-Acetyl-2,5-Dimethylthiophene

    • Product Name 3-Acetyl-2,5-Dimethylthiophene
    • Alias 3-acetyl-2,5-dimethylthiophen
    • Einecs 247-067-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    609902

    Cas Number 13679-70-4
    Molecular Formula C8H10OS
    Molecular Weight 154.23
    Iupac Name 3-acetyl-2,5-dimethylthiophene
    Appearance Colorless to pale yellow liquid
    Boiling Point 218-220 °C
    Density 1.06 g/cm3
    Flash Point 91 °C
    Refractive Index 1.538 - 1.542
    Solubility In Water Insoluble
    Purity Typically ≥98%
    Smiles CC1=CSC(=C1C)C(=O)C
    Synonyms 2,5-Dimethyl-3-acetylthiophene
    Storage Conditions Store at room temperature

    As an accredited 3-Acetyl-2,5-Dimethylthiophene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of 3-Acetyl-2,5-Dimethylthiophene, securely sealed with a screw cap and labeled with hazard warnings.
    Shipping 3-Acetyl-2,5-Dimethylthiophene is shipped in tightly sealed, chemical-resistant containers, protected from light and moisture. It should be transported as a hazardous material according to local and international regulations, with proper labeling and documentation. Temperature control may be necessary to prevent decomposition. Ensure compatible packaging to avoid leaks or spills during transit.
    Storage 3-Acetyl-2,5-Dimethylthiophene should be stored in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep the container tightly closed and stored away from incompatible materials such as strong oxidizing agents. Use proper chemical storage cabinets and clearly label the container. Follow all institutional safety guidelines and local regulations for chemical storage.
    Application of 3-Acetyl-2,5-Dimethylthiophene

    Applications of 3-Acetyl-2,5-Dimethylthiophene in Industrial Manufacturing

    Our production of 3-Acetyl-2,5-Dimethylthiophene supports specialized downstream industries where tailored aroma, flavor, and chemical signatures are crucial for market differentiation, regulatory compliance, and manufacturing efficiency. Below, we detail principal application fields, each with focused technical information to aid clients in formulation, quality control, and process optimization.

    1. Tobacco Flavoring Solutions

    Tobacco manufacturers rely on 3-Acetyl-2,5-Dimethylthiophene to develop customized aromatic profiles in both traditional and reconstituted tobacco blends. Its introduction enhances the sweetness and complexity of the smoke aroma, contributing to sensory appeal while maintaining consistently regulated flavor notes across product batches. Blending protocols require strict integration to meet national and international safety regulations for oral and inhalable products.

    Industry compliance standards

    • GB 16740 (China tobacco additives hygiene standard)
    • FDA (21 CFR Part 182—Generally Recognized as Safe for flavor use, USA)
    • ISO 10939:2018 (Cigarettes—Determination of total and nicotine-free dry particulate matter)
    • ECHA REACH regulations for non-food consumer products

    Typical usage ratio

    • 0.002%–0.01% w/w, commonly adjusted according to blend base strength and targeted flavor intensity.

    Downstream process integration

    • Incorporation during the top flavoring phase post-curing and cutting, dispersed via ethanol or propylene glycol solvents to ensure homogeneous distribution in the tobacco matrix.

    Final product types

    • Filtered cigarettes with enhanced aroma
    • Cigar fillers and wrappers
    • Roll-your-own and pipe tobacco blends
    • Reconstituted sheet tobacco for reduced-risk products

    2. Food Flavor Formulation (Savory and Roasted Notes)

    Food flavor houses utilize this molecule to impart authentic roasted, meaty, and nutty notes in compounded food flavors, particularly for snacks, cooked meats, and sauces. The component's volatility profile complements Maillard-type flavors and maintains taste integrity through thermal processing, making it highly valued in formulations that undergo high-temperature treatments or require stable shelf characteristics.

    Industry compliance standards

    • IFRA (International Fragrance Association) flavor ingredient guidelines
    • FDA 21 CFR 172.515 (USA—flavoring substances and adjuvants)
    • Regulation (EC) No 1334/2008 (EU—flavoring substances in foods)
    • Japanese Food Sanitation Law—Flavor and Spice Additive List

    Typical usage ratio

    • 0.0002%–0.001% w/w in finished foods; varies by matrix and target flavor strength, limited by sensory threshold and maximum permitted levels.

    Downstream process integration

    • Direct addition into compounded liquid or powder flavor bases during the initial blending stage, before flavor encapsulation or spray-drying for inclusion in baking mixes, soups, or seasoning premixes.

    Final product types

    • Instant noodle seasoning packets
    • Snack chips and extruded cereals
    • Prepared gravies and sauces
    • Roasted nut coatings and meat analogues

    3. Fragrance Ingredient Manufacturing

    Our product functions as a key building block in the synthesis of fragrance components, delivering sulfurous, caramelized, and burnt sugar nuances in fine fragrance and home care categories. Perfume compounders integrate this raw material for developing signature accords in oriental or gourmand blends, requiring rigorous documentation and traceability throughout the formulation to meet IFRA and cosmetic safety requirements.

    Industry compliance standards

    • IFRA Standards for restricted fragrance materials
    • EU Cosmetic Regulation (EC) No 1223/2009—Annex III: Cosmetic Fragrances
    • RIFM Monograph: Safety assessments for fragrance ingredients
    • Sustainable sourcing codes (RSPO, ISO 16128—Natural and organic ingredients accounting)

    Typical usage ratio

    • 0.001%–0.02% in concentrate, as per fragrance house scent profiles and end-use application requirements; always below published IFRA exposure limits.

    Downstream process integration

    • Blending into middle or base notes during the fragrance oil compounding step; precise metering via automated dispensing for stability and batch-to-batch reproducibility prior to incorporation into finished perfume or candle matrices.

    Final product types

    • Eau de parfum and extrait
    • Scented candles with caramel or coffee notes
    • Room aerosols and car air fresheners
    • Liquid hand soaps and personal wash products

    4. Chemical Intermediate for Sulfur-Containing Heterocycle Synthesis

    Specialty chemical manufacturers adopt 3-Acetyl-2,5-Dimethylthiophene as a reactive intermediate in the creation of more complex sulfur-containing heterocyclic compounds, used in pharmaceuticals, advanced agrochemicals, and electronic materials. Downstream process steps demand trace impurity control and a fully auditable chain of custody to support end-use registration and certification procedures.

    Industry compliance standards

    • ISO 9001 certified production and traceability
    • ICH Q7 GMP for Active Pharmaceutical Ingredients (where used as API intermediate)
    • REACH registration for chemical substances in Europe
    • GLP—Good Laboratory Practice standards for reference intermediates

    Typical usage ratio

    • Used as a stoichiometric reactant (1.0 equivalent) in multi-step synthesis, with quantities tailored by the downstream molecular target and required output scale.

    Downstream process integration

    • Charged into batch reactors with controlled addition at the cyclization or functionalization stage; monitored for reaction completion before separation, purification, and onward conversion to customer-specified heterocyclic entities.

    Final product types

    • Thienopyridine pharmaceutical intermediates
    • Functionalized thiophene-based agrochemicals
    • High-performance organic electron transport materials
    • Analytical reference chemicals
    Free Quote

    Competitive 3-Acetyl-2,5-Dimethylthiophene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    3-Acetyl-2,5-Dimethylthiophene: Guiding Scent and Flavor Manufacturing with Precision Chemistry

    Introducing Our 3-Acetyl-2,5-Dimethylthiophene: Identity and Chemistry Shaped for Results

    Anyone who has spent years in a chemical plant learns to appreciate the intricate role of specialty aroma chemicals. 3-Acetyl-2,5-Dimethylthiophene stands out in our line because it's not just another thiophene derivative. After handling it day in and out—overseeing distillation, tweaking batch protocols, and fielding questions from both technical and creative users—I have seen that its unique chemistry goes far beyond a CAS number or a purity label.

    Our batches of 3-Acetyl-2,5-Dimethylthiophene bear a consistent golden-yellow clarity and flow readily. The compound’s formula, C8H10OS, brings together a five-membered thiophene ring, two methyl groups, and an acetyl group. This structure underpins much of the charm in both savory flavors and complex fragrances. Over time, specialists notice subtle differences between seemingly similar compounds. Every time I pour this liquid for a new project, it reminds me why careful chemical design has a tangible effect on finished products.

    Properties and What Makes This Compound Stand Out

    Years of fielding technical questions have sharpened my view of this material’s advantages. 3-Acetyl-2,5-Dimethylthiophene comes with a specific gravity near 1.06 and a distinct, persistent odor—rich, nutty, gently onion-like—impossible to replicate with cheaper substitutes or blander hemithiophenes. Where other thiophenes fade into a synthetic haze, this one anchors a savory accord and builds body in top notes. Even in the plant, before the drum is sealed, I can tell by scent whether the last distillation run achieved the right balance or where parameter drift has introduced unwanted notes.

    Our past experience troubleshooting formulations has shown that certain off-odors or color drifts in other products trace back to poorly controlled synthesis or impurities. Our process draws from years of incremental improvements. Through repeated feedback loops between R&D and production, we track color, clarity, GC spectrum, and residual non-volatile content. Working shoulder-to-shoulder with the technical team, we optimized yield, recyclability of solvents, and the energy profile, but these only matter to customers when they translate to reliability in the final product. The low impurity profile means little chance of unpredictable impact on target applications—a fact more applicable than any certified purity number.

    Meeting Real-World Challenges in Flavor and Fragrance Development

    From the flavor chemist’s bench to the automated filling line, the actual benefit of this molecule shows up in how it adapts to broad tasks. In a savory seasoning, a touch of our 3-Acetyl-2,5-Dimethylthiophene brings round, roasted notes and helps bridge top and mid flavors. It builds complexity in tomato, mushroom, pulse, roasted nut and cooked meat applications. Our largest food company customers often point to its transformative effect in low-dosage usage—just a fraction of a percent delivers noticeable roundness and depth.

    When blending for fragrances, the same compound unlocks subtleties in spicy or smoky bases. It reinforces a warm, textured character that supports both natural and synthetic elements. Perfume formulators searching for authentic roasted or nutty notes have found only a few synthetic molecules that hit the target, and this one has just the right threshold and tone to fit.

    In my years responding to calls about batch consistency and help with application, I have noticed formulators expect not just purity, but repeatable olfactory performance. Our process control framework starts with selection of key starting materials, continues through catalytic acylation, and ends with multi-step purification. Batch release requires side-by-side sensory comparison with retained control samples, not only numbers on a chromatogram.

    Comparisons to Other Related Chemicals

    Anyone familiar with 2,5-dimethylthiophene or acetylthiophene relatives quickly points out the difference on their first trial. Simplified methylthiophenes lack the acetyl-driven depth, often coming through too harsh or sulfurous at trace concentrations. We have handled substitutes that break down more easily, oxidize faster, or throw unpredictable off-notes after blending and storage. This specific molecule, with its dual methyl groups and acetyl moiety on the ring, stays stable and clean under typical warehouse or formulation conditions. We keep retention samples from old production lots for years—oxidation cases rarely trouble us compared to other sulfur aromatics.

    For flavorists, the specificity of the acetyl group’s position determines how the compound behaves under Maillard reaction scenarios or in savory emulsions. I have seen projects fail where a positional isomer led to an unwanted metallic or burnt note; side-by-side, the 3-acetyl position brings roundness and warmth where the 2-acetyl or 4-acetyl isomers stay sharper or go off-key at very low blends.

    Fundamentally, the physical handling brings together something else. Many thiophenic compounds resist dilution or react unpredictably with certain solvents: this product dissolves happily in ethanol, propylene glycol, and commonly used food grade carriers. Our technical team runs routine tests for compatibility and solubility, and we regularly get surprised feedback from customers discovering new uses, from canned soups and spice blends to complex fragrance accords.

    Lessons Learned from Production and Quality Control

    Producing batches month after month gives us a sense of where even minor process shifts lead to perceptible product changes. Downtime nearly always costs more than rigorous quality assurance. By tuning reaction time, catalyst quantity, and distillation endpoints, we keep byproducts below critical thresholds. This cuts down on both downstream waste and regulatory headaches.

    Unlike a distributor or outside marketer, we have full visibility into the entire workflow. Every technician checks the batch at several control points—not just relying on final Certificate of Analysis sheets. Our sensory panel works directly with R&D and the plant. That means if a blend fails for a customer, we can trace the chain-of-custody from reactor charge through to filled drum. A trader can only report what’s given; we fix the root cause on site and can often turn around corrections within the ongoing production cycle.

    One especially important aspect involves keeping cross-contamination out—both with other sulfur aromatics and stronger aldehydes. Any experienced flavor lab knows how quickly small residues can bloom in a high-purity thiophene or spoil delicate applications. Our team uses dedicated lines and regular nitrogen sweeps, minimizing the risk of accidental batch carryover.

    Sourcing and Sustainability: Our Direct Approach

    Long-term procurement of raw materials plays a huge role in product stability. Not every manufacturer invests beyond the short-term, but repeat clients drive us to think long-range. Our core values include direct negotiation with upstream suppliers, not least to guarantee uninterrupted access to primary thiophene feedstock. Over the past decade we’ve endured market shocks—price swings, transportation delays, regulatory reviews of hazardous materials—so contingency planning is not a theory here.

    Through deliberate recycling of solvents and careful waste management, we have reduced both the footprint of daily operations and the cost profile for finished product. I remember tracking solvent usage per batch and seeing nearly a 30% reduction over several years, which made both our operations director and our largest flavor house customers happy. Less process waste flows back as lower impurity carryover, delivering tangible advantages to formulators, especially those with strict regulatory and traceability requirements.

    Why Application Feedback Reshapes Everyday Practice

    Direct conversations with customers—big flavor manufacturers and small creative labs alike—reinforce the idea that chemical manufacturing never stops at the loading dock. Sometimes a client calls up reporting an unexpected aroma shift or a blending incompatibility. Through partnership work, we learned that minor manufacturing tweaks affect end-user response. Continuous dialogue lets us adjust process parameters before problems escalate.

    Some of the most interesting feedback comes from technicians outside standardized application routes. I’ve talked with R&D teams repurposing the compound in special applications—vegan burger analogs, specialty spices, new beverage bases—each revealing strengths or flaws not predicted on a data sheet. In one project, a customer flagged a subtle shift in nutty character at extremely low dosages; after a face-to-face visit and reworking a filtration step, we solved the odor issue and gained a longer-term partnership.

    The real world reminds us lab performance doesn’t always translate the same outside small scale tests. Whether it’s a new application or traditional savory blend, our job as actual producers is to take feedback seriously and keep lines of communication open. That’s how we keep this product not just relevant, but in demand among exacting users.

    Quality, Traceability, and Risk: A Manufacturer’s Perspective

    In today’s regulated environment, product traceability forms a bedrock for credibility. We maintain itemized production records, batch retention samples, and detailed audit trails—not just to tick boxes, but to quickly answer regulatory or customer inquiries. Over the years, we’ve weathered multi-country inspections, kosher audits, and sudden requests for historical data.

    More than once we’ve had to retrieve archive drums or redocument a vintage batch for customers under global supply scrutiny. This diligence pays off through repeat contracts, but above all, it brings peace of mind. Traders and resellers look for bulk margin; we look for sustained confidence in both product and relationship. When every batch links to a unique code, and every sample matches benchmarks, it makes solving problems—and preventing them—much easier across many borders.

    Risk always sits just outside the door in chemical manufacturing—a lesson learned from shifts interrupted by broken pumps, variable yields, or supply chain upsets. Success demands both rigorous process management and a willingness to adapt when conditions shift. As producers, we balance immediate customer requirements with long-term regulatory trends, evolving safety standards, and shifting raw material profiles—all while protecting end-user confidence in our product.

    Improvements and Future Directions in Specialty Aroma Chemistry

    True product improvement arises from iterative, sometimes messy steps. Each plant trial, customer discussion, or unexpected hiccup brings information that shapes new operating protocols. A few years ago, our team trialed a new in-line filtration system to reduce trace colored impurities. Customers immediately noticed clearer, more neutral solutions, and this change stuck after comparative analysis confirmed superior performance in finished flavors.

    Sustainability trends prompt constant review of every input—we have started testing bio-based solvents, assessing recovery systems, and sharing updates with customers exploring green or vegan labeling claims. The shift toward transparency in ingredient sourcing has nudged us toward even closer partnerships with vetted thiophene suppliers, as well as routine reviews of all auxiliary chemicals and auxiliary process aids. We know regulations keep changing, so our technical compliance team stays in direct contact with legal and customer-facing teams. No middleman or trading house can match a manufacturer’s insight into the shifting rules, incremental product tweaks, and reliability pressures you have to meet.

    Innovation comes most readily from direct user challenges. A major beverage company once asked if our 3-Acetyl-2,5-Dimethylthiophene could match a fading natural extract in a flavor base. After several bench tests, we reworked part of the downstream process to match not just the GC fingerprint but the headspace aroma profile. Those kinds of challenges keep us on our toes. No one approaches new projects—or old ones—with a one-size-fits-all mindset, so continual improvement remains both a necessity and a source of pride.

    Conclusion: Experience Makes the Difference in Every Drum

    From inside the factory, every shift teaches lessons about chemistry and business alike. 3-Acetyl-2,5-Dimethylthiophene doesn’t just ride on a library of published data, but on the daily choices made by real operators, R&D chemists, sensory analysts, and technical support teams. Over the years, continuous listening—both to machines and to people—has shaped a product that does not just “meet specifications” but reliably supports the creativity, safety, and performance targets customers demand.

    For users in food flavoring, fragrance creation, and specialty aroma development, this compound extends choices, unlocks new notes, and brings a consistent sensory impact where lesser variants fall short. The direct experience of making and supporting this chemical provides a kind of assurance no distributor or reseller can match. Relationships built on technical insight, fast response, and honesty about what works and what needs fixing define our work every day. This is how real chemical manufacturing delivers.