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3,5-Dinitrobenzyl Alcohol

    • Product Name 3,5-Dinitrobenzyl Alcohol
    • Alias m-Dinitrobenzyl alcohol
    • Einecs 209-841-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    576101

    Name 3,5-Dinitrobenzyl Alcohol
    Cas Number 619-84-1
    Molecular Formula C7H6N2O5
    Molecular Weight 198.13 g/mol
    Appearance Pale yellow to yellow crystalline solid
    Melting Point 110-114 °C
    Solubility In Water Slightly soluble
    Density 1.61 g/cm³
    Synonyms m,m-Dinitrobenzyl alcohol
    Pubchem Cid 12485
    Inchi InChI=1S/C7H6N2O5/c10-4-5-1-6(8(11)12)3-7(2-5)9(13)14/h1-3,10H,4H2
    Smiles C1=C(C=C(C=C1[N+](=O)[O-])CO)[N+](=O)[O-]
    Storage Conditions Store at room temperature, protected from light and moisture

    As an accredited 3,5-Dinitrobenzyl Alcohol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 3,5-Dinitrobenzyl Alcohol is packaged in a 25g amber glass bottle, clearly labeled with hazard warnings and chemical information.
    Shipping 3,5-Dinitrobenzyl Alcohol is typically shipped in tightly sealed containers made from compatible materials, protected from light, moisture, and physical damage. It is transported according to regulations for hazardous chemicals, often labeled as harmful or irritant. Proper documentation, handling precautions, and safety measures must be followed during shipping and storage.
    Storage 3,5-Dinitrobenzyl alcohol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of heat, sparks, or open flames. It should be protected from light and incompatible substances such as strong oxidizers and acids. Handle with care, using appropriate personal protective equipment and following relevant safety guidelines for flammable and potentially hazardous chemicals.
    Application of 3,5-Dinitrobenzyl Alcohol

    Applications of 3,5-Dinitrobenzyl Alcohol in Industrial Manufacturing

    3,5-Dinitrobenzyl Alcohol serves as a key intermediate in several highly specialized sectors, delivering unique chemical properties for targeted applications. These applications reflect the material’s established industrial relevance, strict regulatory environment, and tailored process integration as specified by leading downstream manufacturers.

    1. High-Energy Material Synthesis for Explosives and Propellants

    Manufacturers employ 3,5-Dinitrobenzyl Alcohol as a crucial precursor for synthesizing energetic compounds, particularly in the production of insensitive munition explosives and specialized military propellants. Chemical engineers convert it to its nitrate ester or other derivative forms during nitration or condensation, forming energetic compounds with controlled sensitivity and detonation profiles. Facilities adhere to strict process safety, batch documentation, and full traceability to meet both national and international defense regulations governing the handling and conversion of energetic materials.

    Industry compliance standards

    • Military Specifications (e.g., MIL-STD-2105 for explosives sensitivity)
    • International Traffic in Arms Regulations (ITAR)
    • REACH Annex XVII restrictions (Europe)
    • U.S. ATF (Bureau of Alcohol, Tobacco, Firearms and Explosives) storage and processing permits

    Typical usage ratio

    • 10–25% by mass of formulation, adjusted based on target energy output and sensitivity controls

    Downstream process integration

    • Direct addition to nitrate esterification reactors or condensation steps after pre-mixing with plasticizers and stabilizers
    • Closely monitored feeds to limit exothermic spike and ensure batch homogeneity

    Final product types

    • Insensitive munition compositions (e.g., IMX-series, DNB-alcohol-derived explosive fillers)
    • Solid rocket propellant binder additives
    • Detonator and booster charge substrates

    2. Pharmaceutical Intermediate for Active Pharmaceutical Ingredient (API) Synthesis

    Pharmaceutical companies utilize 3,5-Dinitrobenzyl Alcohol as a targeted building block in the multi-step synthesis of APIs, such as certain nitroaromatic drugs or intermediates for central nervous system (CNS) agents. The alcohol group undergoes controlled substitutions or reductions, generating intermediates with stringent purity profiles. All operations—including batch production, purification, and in-process QC—must follow global cGMP and pharmacopeia standards to support regulatory filings and pharmaceutical supply chain traceability.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF Monograph Related Substances Testing (if applicable)
    • EU GMP Vol. 4 Annex 13 for API intermediates
    • FDA 21 CFR Part 210/211 controls

    Typical usage ratio

    • 10–40 mol% as reactant, depending on target intermediate yield and desired synthetic route, with adjustment for in-process losses

    Downstream process integration

    • Entered during multi-stage aromatic substitution or reduction steps, with close monitoring of temperature and solvent polarity
    • Purified post-reaction by recrystallization or chromatography to meet low impurity requirements

    Final product types

    • Nitro-containing pharmaceutical intermediates
    • Custom APIs for research and orphan drug markets
    • Precursors for CNS drug candidates

    3. Specialty Dyes and Pigments Intermediate

    Producers of advanced colorants adopt 3,5-Dinitrobenzyl Alcohol as a functional intermediate for developing azo and nitroaromatic dyes, particularly in applications requiring high thermal stability and UV resistance. The alcohol group introduces greater solubility control in the dye molecules and allows further derivatization with sulfonic and carboxylic acids. The formulation process involves stringent quality control to ensure color consistency and lack of banned amine derivatives, mandated by both industrial partners and consumer goods regulations.

    Industry compliance standards

    • Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH) for azo dyes
    • EN 71-3 Toy Safety Regulation (migration of certain elements in colored plastics)
    • Oeko-Tex Standard 100 limited amine requirement
    • ISO 9001:2015 certified dye plant processes

    Typical usage ratio

    • 5–18% by weight in final dye batch, with ratio optimized for hue depth, solubility, and fastness properties requested by specific end-users

    Downstream process integration

    • Introduced at initial coupling or diazotization to form base dye molecules
    • Further processed with coupling agents for pigment development or granulation

    Final product types

    • UV-stable synthetic dyes for plastics and polymers
    • High-temperature textile colorants
    • Microparticle pigments for digital printing inks

    4. Fine Chemical Synthesis for Research and Development

    Chemical R&D and contract synthesis labs source 3,5-Dinitrobenzyl Alcohol for the preparation of custom nitroaromatic compounds, ligand scaffolds, and probe molecules. Researchers employ precise stoichiometry, often under inert atmospheres, to prevent side reactions and maintain high yields of targeted derivatives. Documentation of synthesis parameters remains critical for supporting intellectual property filings, reproducibility in peer-reviewed studies, and transfer to scale-up facilities. Shipments adhere to established hazardous material handling and reporting protocols.

    Industry compliance standards

    • OECD Good Laboratory Practice (GLP) guidelines for chemical synthesis
    • International Air Transport Association (IATA) Dangerous Goods Regulations
    • EPA TSCA Reporting—Chemical Research & Development Exemption
    • Local institutional health and safety (IHS) policies

    Typical usage ratio

    • Varies based on reaction scale, typically 1–10 mmol per assay, scaled upward for pilot batches

    Downstream process integration

    • Added as core or peripheral functional group in multi-step small-molecule synthesis
    • Strict temperature, solvent, and atmosphere controls throughout reaction cycle

    Final product types

    • Custom nitroaromatic standards
    • Molecular probes and chemical reagents
    • Ligand systems for catalysis research
    Free Quote

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    Certification & Compliance
    More Introduction

    Introducing 3,5-Dinitrobenzyl Alcohol from a Manufacturer’s Lens: Reliable Quality, Consistent Outcomes

    Meeting Real-World Needs in Fine Chemical Synthesis

    In direct synthesis rooms, every step counts. Consistency in intermediates determines how the next stage unfolds. Across multiple batches, 3,5-Dinitrobenzyl Alcohol stands out for its role as a practical building block in both research and industrial-scale production. This aromatic alcohol—with a dinitro substitution pattern at positions 3 and 5 on the benzene ring—offers unique reactivity and selectivity for those seeking robust intermediates in pharmaceuticals, agrochemicals, and specialty dyes.

    On the manufacturing side, attention to detail starts early. A slight impurity in dinitrobenzyl alcohol affects the downstream outcome. Production teams monitor raw material sources and maintain process parameters at every batch. Skilled hands adjust temperatures, manage reaction times, and sample at critical points. Direct feedback from both lab and field applications informs every decision—from batch filtration to drying protocols. It also drives continuous process improvement and has led to material that customers can test, trust, and build upon.

    Common Uses: Efficiency and Functionality in Practice

    This compound isn’t just another aromatic alcohol. Teams in pharmaceutical process development turn to 3,5-Dinitrobenzyl Alcohol because it serves as a versatile intermediate in the synthesis of many active molecules. Its electron-withdrawing nitro groups help direct further substitutions on the aromatic core, making it a valued starting point. In agrochemical discovery, this product shows up repeatedly as a scaffold for pesticide leads. Dyes based on dinitrobenzyl alcohol often display vivid, stable colors because the nitro substitution brings lightfastness and resistance to degradation—factors critical for fabric and material applications.

    Year after year, processors have counted on this product due to reliable yields and ease of tailoring downstream chemistry. Teams appreciate low byproduct formation and reduced side-reactions—a testament to how upstream quality simplifies bench chemistry. Production chemists in external partnerships have spoken about batch-to-batch repeatability, which saves time during scale-up and pilot runs. Insights like these drive demand, as industry chemists report fewer purification steps and more predictable impurity profiles.

    Manufacturing Standards and Consistency

    In large-scale units, we have seen that temperature control during nitration and reduction defines product purity far more than one might anticipate. Routine, hands-on testing of melting points and chromatographic fingerprints confirms our commitment to genuine batch consistency. Standard production at industrial scale delivers 3,5-Dinitrobenzyl Alcohol with a purity exceeding 99%. Color and odor remain critical quality attributes as well, often indicating subtle differences in trace impurities. Such sensory checks, while less formal, have saved entire runs from costly rework.

    Effective solvent recovery and environmental controls have become a real focus for chemical manufacturing, not just an afterthought or bureaucratic requirement. Closed-loop cooling and scrubbing, solvent distillation, and spent acid neutralization now stand side by side with yield and purity on the plant floor. Investment in analytical instrumentation and staff training reflects both regulatory requirements and market expectations, as more buyers require not only certificates of analysis but transparent proof of sustainable practices behind each kilogram.

    How It Differs from Other Aromatic Alcohols

    Chemically, 3,5-Dinitrobenzyl Alcohol distances itself from simpler analogs by its pronounced electron-withdrawing groups. Nitro substituents at these particular locations alter reactivity in ways plain benzyl alcohol never can. For example, nucleophilic attacks on the benzylic position become easier to control, leading to improved selectivity in alkylation or oxidation reactions compared to products like 4-nitrobenzyl alcohol or unsubstituted varieties. The two nitro groups also enhance the substrate for further functionalization, opening the door to a broader set of derivatives.

    From the manufacturing perspective, the nature of the nitro groups requires more careful control during reduction and purification than other isomers or mono-substituted analogs. It’s not simply a small change in synthetic route; the additional electron-withdrawing power of the two nitro groups influences product stability, shelf life, and even handling procedures. Teams will often note that automated dosing and diligent waste management become more critical with this intermediate compared to mono-nitrated or non-nitrated benzyl alcohols. Batch notes often reflect long-term learnings about filtration speeds, mother liquor reuse, and bottleneck reactions unique to this product.

    Supporting Our Partners: Knowledge Exchange

    Collaborations with process chemists and R&D labs influence more than technical specifications; they shape how we manage raw materials and train production staff. Customers share information about the specific challenges they encounter, such as solubility issues in large-scale crystallization or handling characteristics that affect throughput in continuous production lines. Drawing on these insights, we fine-tune drying times, rework handling steps, and maintain robust packaging standards suited for both research quantities and bulk logistics.

    Partnerships bring feedback loops that reveal new uses. In the past, minor adjustments in how we neutralize post-reaction mixtures or monitor color shifts during crystallization have come from suggestions made by synthetic chemists outside our own ranks. Sharing what works—and what leads to delays or reprocessing—turns the conversation from mere supply-and-demand to direct problem-solving. We routinely update handling guidance and packaging methods based on real, field-level feedback rather than assumptions from a distant office.

    Application Focus: Quality Where It Matters

    The right level of purity matters most in final-stage pharmaceutical intermediates. Researchers need a reproducible product that fits naturally into their synthetic route. No one wants hidden byproducts that complicate purification or require extra column time. Dyes and pigments have similar concerns; any trace impurities affect hue, stability, or longevity of the final application. By keeping impurity profiles tight and documenting each change in process, our technical team assures customers they can build and scale with confidence.

    In practice, shipping an intermediate like 3,5-Dinitrobenzyl Alcohol goes beyond just filling drums to a stated weight. Inspection teams flag off-color batches or sediments that escape drying protocols. New staff receive hands-on training for these sensory and analytical checks—sometimes catching quality issues even before instruments do. In the rare event of a rejected shipment, traceability reports connect every drum back to its production batch, complete with logs of temperatures, pH, and operator notes.

    Sustainability and Environmental Footprint

    From the plant floor, reducing waste streams and optimizing resource efficiency is more than simple compliance. We have redesigned how process water and solvents are recycled, with closed recovery systems and real-time monitoring to reduce both emissions and raw material loss. By moving toward more concentrated reaction conditions, we have cut down process times, resulting in both energy savings and lower production costs. This sustainable approach did not happen overnight; it followed a process of identifying bottlenecks, trialing alternative reactors, and actually running side-by-side comparisons over months rather than hours.

    Our team tracks both regulatory developments and practical innovations—such as advances in green chemistry or safer waste acid treatment—to incorporate into daily work. These standards keep both staff and neighbors protected and assure industrial customers that responsible production aligns with broader environmental goals. Success at scale involves looking past cost alone; adopting more rigorous process controls and investing in improved filtration equipment persist as ongoing efforts to both meet market demand and reduce the overall ecological footprint.

    Scalability: Lessons Learned from the Production Floor

    Scaling up often reveals difficulties not seen at laboratory scale. Crystallization rates change. Impurities—hardly noticed in the glassware—become significant hurdles by the kilogram. Our manufacturing team maintains both pilot and full-scale reactors, and we have learned that decisions such as coolant circulation speed, agitation power, and even vessel geometry can swing yields and purities by more than one-percent margin. These changes affect not just cost but the real-world usability of the material for our customers.

    Batch control records, empirical temperature and pH profiles, and hands-on experience all shape the final output as much as any theoretical route. Effective scaling comes from knowledge built over years: the right way to time additions, the practical limits of solvent recovery, and countless other “minor” tweaks make or break a run. Avoiding generalized advice, we rely on comparative data and constant operator feedback to maintain standards across small, medium, and bulk batches.

    Technical Support Backed by Experience

    Customers value support based on actual production experience—not just standard responses from an MSDS sheet. Our technical team provides hands-on guidance around storage stability, optimal transfer conditions, and formulation compatibility for intermediates. If a partner reports clumping or unexpected color in a large-volume batch, we investigate both in our own plant and, if possible, at the customer’s site with their process team. This back-and-forth dialogue enables solutions grounded in reality: adjusting packaging atmospheres, rethinking warehouse rotation, or in one case, reevaluating an entire upstream supplier of a critical co-reactant.

    A blend of scientific knowledge and practical, shop-floor insight sets the highest standard for support. Troubleshooting becomes more than checking boxes—it’s about seeing the issue through the eyes of the people actually making or using the product. Our own staff develop expertise not just through manuals but through continual exposure to the full production cycle, from raw material inspection through finishing, packaging, and logistics. The difference shows up not only in technical specs but in customer feedback about fewer delays and more successful launches.

    Compliance, Certification, and Market Expectations

    Maintaining up-to-date documentation for each batch forms the backbone of both regulatory and quality assurance practices. Each lot that leaves the plant arrives backed by trackable records—analytical results, origin of raw materials, process controls, and handling logs. This transparency gives customers in regulated markets, such as pharmaceuticals or crop protection, the assurance required for their own compliance requirements.

    Market expectations evolve quickly. Certifications for quality systems, environmental standards, and safety practices provide buyers and regulatory agencies the evidence needed for audits and traceability. These systems aren’t theoretical: process audits physically walk through the plant, inspecting logbooks and interviewing operators about every step. Lessons from these audits feed directly back into both policy and everyday routines—raising standards across the board and giving customers the confidence to trust the source as much as the specification sheet.

    Adaptability to Customer-Specific Needs

    Even as large-volume batches often drive production schedules, smaller, specialty orders keep new procedures and innovations top-of-mind. Labs running pilot projects, process development units experimenting with scale-up, and industrial formulators pushing boundaries provide the real-world test for batches outside the standardized bulk runs. These orders challenge teams to adjust volumes, drying protocols, or packaging in ways that improve not only immediate results but set new standards for future batches.

    Direct customer conversations guide these adaptations. Whether dealing with seasonal spikes, new application routes, or special storage requirements, open channels for technical and operational dialogue make the difference. Our experience says the smallest requests—say, tweaking granulation or ensuring a specific headspace in packaging—often reveal broader areas for production improvement, resulting in smarter processes at every stage.

    Long-Term Value: More Than a Commodity

    3,5-Dinitrobenzyl Alcohol delivers crucial value to those pushing for breakthroughs in life sciences, crop protection, and functional materials. Its utility as an intermediate means that every kilo conserves both research time and resources, allowing teams to focus on innovation rather than troubleshooting base chemistry. Beyond meeting expected specifications, we aim to foster long-term relationships grounded in transparency, problem-solving, and direct testimony from production experience.

    Every change in the supply chain, regulatory landscape, or process technology ultimately shapes both product and partnership. Over time, the lessons learned—on shifts, in lab benches, during emergency troubleshooting, and through customer calls—become the real foundation for reliability and trust. True quality in 3,5-Dinitrobenzyl Alcohol means not just technical excellence but adaptive, grounded, and direct insight into what keeps industry moving forward.