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HS Code |
603698 |
| Chemical Name | 3,5-Dinitro-2-Methylbenzoic Acid |
| Cas Number | 618-86-0 |
| Molecular Formula | C8H6N2O6 |
| Molecular Weight | 226.15 |
| Appearance | Yellow crystalline powder |
| Melting Point | 178-182°C |
| Solubility In Water | Slightly soluble |
| Boiling Point | Decomposes |
| Density | 1.59 g/cm3 |
| Synonyms | 2-Methyl-3,5-dinitrobenzoic acid |
| Pubchem Cid | 12047 |
| Inchi Key | CVITZOMGFQMHRN-UHFFFAOYSA-N |
As an accredited 3,5-Dinitro-2-Methylbenzoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 25 grams of 3,5-Dinitro-2-Methylbenzoic Acid, tightly sealed with a screw cap and safety label. |
| Shipping | **Shipping Description for 3,5-Dinitro-2-Methylbenzoic Acid:** This chemical should be shipped in tightly sealed containers, protected from moisture and direct sunlight. It is classified as a hazardous material and must be handled with care, using proper labeling and documentation, in accordance with local, national, and international regulations for transport of dangerous goods. |
| Storage | 3,5-Dinitro-2-Methylbenzoic Acid should be stored in a tightly sealed container, away from light, heat, and sources of ignition. Keep it in a cool, dry, well-ventilated area, isolated from incompatible materials such as strong bases and reducing agents. Use proper personal protective equipment when handling, and store in accordance with institutional and regulatory guidelines for hazardous chemicals. |
Applications of 3,5-Dinitro-2-Methylbenzoic Acid in Industrial Manufacturing3,5-Dinitro-2-methylbenzoic acid serves as a specialized intermediate in the synthesis of fine chemicals across multiple industrial segments. As a manufacturer with direct synthesis capabilities, we supply this compound to established downstream sectors that leverage its unique reactivity for targeted, high-value applications. The following sections detail verified usage scenarios, highlighting industry standards, practical formulation rates, integration into end-user processes, and the resulting product categories. 1. Pharmaceutical Intermediate for Active Pharmaceutical Ingredient (API) SynthesisThis compound consistently appears in multi-step organic syntheses within the pharmaceutical sector, particularly as a building block for niche APIs including certain vasodilators and experimental oncology drugs. End users adopt it for the introduction of the dinitrobenzene moiety under controlled GMP environments, often requiring stringent material specifications and documentation. Industry compliance standards
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2. Dye and Pigment Manufacturing IntermediateProducers of specialty azo, nitro, and anthraquinone-based dyes employ this raw material for precise molecular modifications required for custom shade development and stability optimization in high-performance colorants. Its electron-deficient aromatic structure facilitates selective coupling and functionalization for demanding textile and industrial pigment requirements. Industry compliance standards
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3. Agrochemical Active Ingredient SynthesisLeading agrochemical formulators utilize this nitroaromatic acid as an intermediate in the production of crop protection actives. Its functional groups enable chain extension and customized substitution in the synthesis of herbicides and fungicides where chemical stability under field conditions is critical. Industry compliance standards
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4. Synthesis of High-Performance PolymersChemical process engineers sourcing advanced aromatic monomers for specialty polymers employ this acid in the development of nitro-functionalized resins. Its structure aids in producing thermally stable polymers with nitro-aromatic blocks, often required for specialty adhesives, coatings, and engineered plastic materials where conventional monomers fall short. Industry compliance standards
Typical usage ratio
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5. Analytical Reagent ProductionSpecialty reagent manufacturers use this compound as a reference standard and derivatization agent in chemical analysis, particularly for detecting trace amines and nitro compounds in environmental and forensic laboratories. The high purity and consistent structure support its application in calibration mixtures and reaction endpoint controls. Industry compliance standards
Typical usage ratio
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On the production floor, each batch of 3,5-Dinitro-2-Methylbenzoic Acid tells its own story. In our plant, we track every process variable, from the nitration temperature curve to the filtration sequence. The 3,5-dinitro configuration doesn’t just pop up—it requires careful handling of reagents and strict controls over heat and pH. Even with years of making this compound, we respect its stubbornness: dinitro-methylbenzoic acid refuses to give consistent yield unless run parameters stay close to the bone. Every glass-lined reactor and all high-precision pressure filters in our shop have seen their share of both successful and difficult batch records.
We do not offer it as another routine chemical. It is a starting material for challenging reactions downstream. Analysts and chemists working on dyes, pigments, and custom pharmaceuticals pick our 3,5-Dinitro-2-Methylbenzoic Acid for its purity. Consistent 99%+ assays mean less surprise on the HPLC and fewer headaches post-synthesis. High-purity means less coloured byproducts, less work at the chromatography bench, better batch-to-batch consistency. In our experience, even a half percentage off-purity can lead to lost time, cleaning columns and reprocessing. Our clients watch chromatograms closely; manufacturers like us sort out the hard parts before the drums even leave the plant gate.
Many recognize this acid as a robust methyl-dinitrobenzoic scaffold. In surfactant or pigment labs, technicians reach for it for its predictable reactions and workable solubility profile. Unlike some other aromatic acids, our product dissolves readily under the right alkaline or polar organic conditions. Through multiple runs, we have dialed in particle distribution—the fine, free-flowing granularity supports both small-lot and dump-to-drum mixing at any scale. That’s crucial downstream, especially if you are laying down consistent intermediates for technical-grade dyes or exploring conjugates in medicinal chemistry. We never cut corners on filtration or drying, and experienced purchasers see this as soon as they open a new drum: off-white, free of visible clumps, ready for the next step.
Chemistry students ask about the difference between 3,5-Dinitro-2-Methylbenzoic Acid and other isomers or related nitrated benzoic acids. The answer lies in field experience—batch makers and lab heads quickly sense how this compound handles differently from 2,4-dinitro analogues or single-nitro substitutes. Take nitration: the 3,5-dinitro pattern means electron density pulls in a way that resists overnitration yet still allows efficient further functionalization. We see routine requests for special lot certifications—some customers require strict halogen or metal trace limits, often tied to sensitive downstream bioconjugate or dye development steps.
Most benzoic acid derivatives look similar in the catalog. This one stands apart through its defined melting range, solubility behavior, and, above all, the reliability of its reactivity. From our own plant’s records—and close feedback from scale-up partners—chemists find it more forgiving than 2,6- or 3,4-dinitrobenzoic acid in condensation reactions. That stability delivers value. Trials run cooler, reaction workups stay simpler, and less time ends up lost purifying the impurity profile that follows touchier isomers.
We go beyond basic purity numbers. Trace water content stays low, not by guesswork but thanks to tight monitoring in our drying step. Granule sizing isn’t just for appearance; uneven particle size can throw a reaction off if you’re dosing into high-shear mixers or automated lines. Quality assurance sets limits for insolubles and color that actually mean something on the plant floor—batches with visible residue or abnormal hue get isolated until we resolve the root cause. No one appreciates load rejections, whether you’re working at the lab bench or prepping for a multi-ton synthesis.
After twenty thousand kilos of production, the details become muscle memory. Any deviation—an unexpected TLC spot, a slow filtration in final washing—brings the team together to root out the issue. We run Karl Fischer titrations, melting point checks, and HPLC profiles on every lot before release. Experienced end-users know the difference real quality makes: it leads to trustworthy intermediate lots and keeps costs in check over the long term.
We don't just scale up recipes from old literature or follow textbook pathways. The reality of 3,5-Dinitro-2-Methylbenzoic Acid production today involves robust solvent recovery, emission controls, and energetic safety reviews. While some players claim to “optimize” by skipping rigorous environmental controls, our approach factors in operator safety, waste stream minimization, and scrubber efficiency. Over the years, our team has developed cleaner synthesis cycles that recover more mother liquor, yield fewer side products, and reduce the load on downstream water treatment.
By putting in the work up front with solvent choices and nitrator vessel configuration, we keep costs contained and deliver consistent performance. This also pays off for customers. Environmental audits matter more than ever, and brands linked to negative supply chain events face real business risk. Our partners count on us to give them more than just a certificate—they rely on us to run compliant, auditable processes that hold up even under third-party review.
We have shipped 3,5-Dinitro-2-Methylbenzoic Acid to dye makers, pharmaceutical research labs, and specialty pigment facilities worldwide. Each application pulls on a different feature, but consistent quality remains the foundation. In organic synthesis, chemists appreciate the acid’s specificity—two nitro groups at meta positions unlock aromatic substitution routes that aren’t possible with other isomers. The methyl group lends increased solubility in organics, and that makes life easier in certain coupling, reduction, or acryloylation protocols.
Some operators use this acid to introduce selectivity into their colorant lines. The position of the nitro groups imparts reliable tone and depth to synthetic pigments, making color-matching and batch correction far easier. In our own pilot studies, we’ve seen product developers move more quickly from bench to pilot scale because our lots maintain the same impurity profile every time. In another area, drug discovery teams rely on the predictable electronic properties of this core for robust linker development—they skip time-consuming batchwise extra purification because our acid leaves little behind to clean up after.
Pharmaceutical-grade and technical users ask for custom packaging, dust-reduced lots, and selective sieved fractions. We meet those demands by running purpose-built lines and scheduling regular quality revues, ensuring no accidental cross-contamination or packaging errors. For smaller-scale R&D, we deliver lab packs with the same thorough batch data as our bulk lots. Larger buyers appreciate our stable supply history—we keep disruptions minimal by buffer-stocking and forecasting based on real production, not guesswork.
Over the years, we have learned that stable production beats risky shortcuts every time. Some competitors chase lower costs by outsourcing steps or relaxing specs, but our view remains unchanged: trust comes from doing the hard work and standing by the result. On every lot, we document synthesis steps, reagent lot numbers, key process variables, and full analytical results. This habit builds traceability and instils confidence in every kilo we release.
Occasionally, process upsets do occur—no chemical plant operates with perfect predictability. When a batch falls out of specification, our team launches root-cause analysis before the drums ever reach a loading dock. This discipline keeps downstream users safe from lost time or contaminated intermediates. By staying true to this approach, we have earned long-term partners who value not just the product, but the reliability behind it.
Customers often weigh our product against alternatives like 2,4-dinitro or 3,4-dinitrobenzoic acid. On-paper specs can look close, so we encourage side-by-side trial runs. 3,5-Dinitro-2-Methylbenzoic Acid stands out through its reproducible reactivity and cleaner profile at typical reaction conditions. We have seen users report higher conversion rates and fewer gelled residues—especially in multi-component condensations or in pigment intermediates—when they switched over.
The methyl group’s presence affects solubility, boiling point, and even downstream colour stability. We tune our process to capture this difference. While it doesn’t suit every purpose, it proves reliable where others cannot. Plants making high-purity access intermediates value the way our acid integrates into their process, providing a smoother synth and a straightforward path to QC release. This usability goes deeper than paperwork; it’s a result of how our team understands both upstream synthesis and the pain points users face downstream.
We keep our ears open. Technical calls, quality surveys, or field visits to our customers reveal new angles for improvement every year. More than once we have retooled a drying cycle, adjusted granularity, or consulted on impurity suppression after feedback from formulation chemists trying new approaches. This loop of listening, learning, and acting creates a better supply chain for everyone involved.
Over the last decade, customer demand for stricter trace metal content, lower volatile organics, and ever-tighter color index limits has only grown. We invested in higher-precision chromatography and elemental analysis, because quality demands grow more complex every year. Instead of pushing the risk down the supply chain, we absorb it up front—so you can ship your own final products with confidence in both performance and safety.
The real world doesn’t care for textbook recipes. Machinery can falter, raw materials vary, and market pressures shift fast. During global supply disruptions or sudden regulatory shifts, we’ve kept our commitments by holding transparent conversations with customers. If a batch looks questionable, we communicate directly, share details, and propose options. Building high-trust relationships with manufacturers, formulators, and researchers means more work, but it pays out when deadlines loom and markets move.
Waste reduction and energy savings matter, not just for compliance but for financial sense. By capturing more solvents and reducing unwanted byproducts, our own material inputs and disposal costs drop. We see this as part of our responsibility as a steward of both chemical tradition and modern sustainability standards. Every improvement makes the process a little cleaner, the batches a little more consistent, and the operators’ jobs safer.
Getting the right lot of 3,5-Dinitro-2-Methylbenzoic Acid makes or breaks entire campaigns. Downstream chemists worry about fewer variables when they use material with a proven record. In the specialty pigment sector, batch tone shift can delay shipping and eat at margins. In pharma research, an off-spec lot introduces days of troubleshooting into timelines no one can afford. R&D managers want more than a generic spec—they demand supplier transparency, adaptable packaging, and process knowledge that runs deeper than a sales catalog.
We meet these challenges by treating every order as a partnership. Our technical staff understands how this acid slots into both established and experimental syntheses. We’ve helped partners troubleshoot scale-up issues, supplied second-lot references for regulatory submissions, and offered tailor-made analytical support for custom applications. This flexibility strengthens both our product profile and our customers’ programs all over the world.
Demand grows for high-purity building blocks that perform under tough conditions. Our experience with 3,5-Dinitro-2-Methylbenzoic Acid proves the value of investment in quality, attention to operation detail, and a strong safety culture. Whether evolving to meet new environmental codes or adapting synthesis routes for cost savings, we believe in open dialogue and transparent performance data. By focusing on both chemical rigor and the needs of end-users, we bridge the gap between traditional manufacturing and modern innovation. Every lot shipped builds our reputation—and we stand behind every kilogram.