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3,5-Dichlorobenzylamine

    • Product Name 3,5-Dichlorobenzylamine
    • Alias 3,5-DCBA
    • Einecs 220-123-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    122345

    Name 3,5-Dichlorobenzylamine
    Cas Number 13368-05-3
    Molecular Formula C7H7Cl2N
    Molecular Weight 176.05
    Appearance White to slightly yellow solid
    Melting Point 51-53 °C
    Boiling Point 273-275 °C
    Density 1.34 g/cm³
    Solubility Slightly soluble in water
    Purity Typically ≥98%
    Smiles C1=CC(=CC(=C1Cl)Cl)CN
    Inchi InChI=1S/C7H7Cl2N/c8-6-1-5(4-10)2-7(9)3-6/h1-3H,4,10H2
    Storage Temperature Store at room temperature

    As an accredited 3,5-Dichlorobenzylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 grams of 3,5-Dichlorobenzylamine, sealed with a green screw cap, hazard and identification labels attached.
    Shipping 3,5-Dichlorobenzylamine is typically shipped in tightly sealed containers made of compatible materials to prevent leaks or contamination. It should be packed according to local and international regulations for hazardous chemicals, labeled clearly, and protected from moisture, heat, and direct sunlight during transit. Appropriate safety documentation accompanies each shipment.
    Storage Store 3,5-Dichlorobenzylamine in a tightly sealed container in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers and acids. Keep the storage area away from direct sunlight and sources of ignition. Clearly label the container, and ensure proper ventilation to prevent vapor accumulation. Follow standard laboratory chemical storage guidelines and wear appropriate personal protective equipment when handling.
    Application of 3,5-Dichlorobenzylamine

    Applications of 3,5-Dichlorobenzylamine in Industrial Manufacturing

    As a direct manufacturer of 3,5-Dichlorobenzylamine, we support multiple industrial customers in regulated sectors that require precise chemical performance and traceable quality for advanced synthesis and downstream processing needs. Below are the specialized scenarios where our product delivers value in line with actual end-market practices, supporting industry compliance, reliable formulation, efficient integration, and high-quality finished goods.

    1. Pharmaceutical Intermediate for Antibacterial Drug Synthesis

    In pharmaceutical manufacturing, 3,5-Dichlorobenzylamine acts as a key intermediate in the synthesis of certain benzylamine-based pharma APIs, particularly those targeting bacterial and fungal infections. It enables regioselective amination steps, influencing molecular structure and biological activity while meeting strict regulatory documentation and batch traceability. Downstream processes rely on its purity to minimize side reactions during multi-step syntheses.

    Industry compliance standards

    • EU GMP (Good Manufacturing Practice for APIs, EudraLex Vol 4, Part II)
    • ICH Q7 (Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients)
    • USP <1092> Pharmaceutical Compounding – APIs
    • Chinese Pharmacopoeia ChP 2020 (for relevant registered drugs)

    Typical usage ratio

    • 50–200 g per mole target API, adjusted to batch scale and specific stoichiometry of the amination or condensation reaction step

    Downstream process integration

    • Charged during first or second stage of multi-step organic synthesis in reactor vessels; reacts with halogenated benzenes in presence of base and solvent; followed by extraction, purification, and crystallization to isolate intermediate compounds

    Final product types

    • Semi-synthetic antibacterial agents (e.g., dichlorobenzylamine derivatives APIs)
    • Active pharmaceutical ingredients for topical and oral dosage forms
    • Precursor building blocks for CNS and antifungal medications
    • Research reference standards in pharmaceutical labs

    2. Raw Material in Agrochemical Active Ingredient Synthesis

    Within the crop protection sector, manufacturers use this aromatic amine as a building block in the development of select fungicides and herbicides, specifically for derivatives that require electron-withdrawing substitution patterns. Its controlled reactivity ensures consistent yields and minimal environmental residues, supporting the synthesis of regulated agrochemical actives in compliance with international residue and environmental safety standards.

    Industry compliance standards

    • FAO/WHO Specification for Plant Protection Products
    • ISO 16140:2016 (Microbiology of the food chain)
    • REACH Regulation (EC) No 1907/2006
    • China GB/T 1604-2019 (Quality standard for agrochemical intermediates)

    Typical usage ratio

    • 60–250 g per kg target agrochemical active; ratio depends on the synthetic route and product's designed substitution pattern

    Downstream process integration

    • Added to aniline condensation reactions or nucleophilic aromatic substitution stages in closed reactors; followed by quenching, extraction, and column chromatography used to isolate purified actives before formulation

    Final product types

    • Active ingredients for selective herbicides (chlorinated benzylamine derivatives)
    • Systemic fungicide cores for broad-spectrum field applications
    • Seed treatment micro-emulsions
    • Technical grade pesticide intermediates

    3. Specialty Dye Intermediate for Azo and Phthalein Pigments

    Industrial dye and pigment manufacturers select this dichloro-substituted aromatic amine as an intermediate for colorants that demand chemical resistance and fastness. It facilitates azo coupling and phthalein linkage—producing high-value pigments for plastics, printing inks, and fiber coloration. The purity and consistent performance meet batch color quality and regulatory testing, enabling compliance in tightly monitored applications.

    Industry compliance standards

    • Oeko-Tex Standard 100 (certification for textile dyes)
    • EN 71-3:2019 (Safety of toys – migration of certain elements)
    • REACH Annex XVII (Restrictions on certain hazardous substances in dyes)
    • ISO 787/5-1980 (General methods of test for pigments and extenders)

    Typical usage ratio

    • 35–120 g per kg pigment, based on the specific dye structure, final color shade, and targeted product strength

    Downstream process integration

    • Introduced at the intermediate synthesis or coupling step for azo dye or pigment formation; often dissolved in an organic phase and reacted with diazonium salts before isolation and purification

    Final product types

    • High-performance azo dyes for printing inks and plastics
    • Phthalein pigments for polyester and acrylic fibers
    • Heat-resistant colorants for technical textiles
    • Pigment concentrates for industrial paints

    4. Intermediate in Chemical Synthesis of Polymer Additives

    Producers of performance polymers and resins utilize this aromatic amine as a precursor for stabilizers and chain modifiers, specifically where chlorine substitution imparts lightfastness, UV stability, or flame retardancy. The compound enters reaction stages targeting tailored additive structures for engineered plastics, ensuring compliance with global food contact and flame resistance regulations.

    Industry compliance standards

    • FDA 21 CFR 177.1520 (Olefins polymers for use in contact with food)
    • UL 94 (Standard for Safety of Flammability of Plastic Materials)
    • GB 9685-2016 (Standards for use of additives in food contact materials in China)
    • RoHS Directive (2011/65/EU) for restricted substances in electrical/electronic applications

    Typical usage ratio

    • 10–85 g per kg additive compound; tailored to achieve the desired stabilizing effect or regulatory compliance in the final plastic matrix

    Downstream process integration

    • Charged into pilot or production-scale reactors during intermediate additive synthesis, often via alkylation, amidation, or urea formation, before additive is compounded into polymer resins through melt kneading or extrusion

    Final product types

    • Light stabilizers for polypropylene or polyethylene
    • Reactive flame retardant additives
    • Processing aids for specialty resins
    • Antioxidant systems for engineering plastics
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    Certification & Compliance
    More Introduction

    Introducing 3,5-Dichlorobenzylamine: Proven Quality from a Dedicated Manufacturer

    The Know-How Behind 3,5-Dichlorobenzylamine

    From decades of hands-on experience, we know that there isn’t much room for error when producing specialty chemicals. 3,5-Dichlorobenzylamine stands out in our line-up. This compound’s full chemical name packs a punch, but in actual practice, it’s the results and reliability our customers focus on. Each drum and batch we create follows a process refined by experience, not just by theory. Over the years, we’ve worked through the production pitfalls—reactor fouling, impurity issues, and achieving purity standards that don’t just look good on paper. In the chemical plant, what matters most is whether the chemical does the job safely, consistently, and predictably.

    Consistent Quality, Direct from the Plant

    We produce 3,5-Dichlorobenzylamine to meet the needs of factories that demand consistency. Far too often, we’ve heard about users switching suppliers only to hit a wall: traces of unwanted byproducts, poor flowability, or contamination popping up in critical reactions. Our quality control doesn’t stop at HPLC readings or a passing GC trace. It means keeping our lines calibrated, staying on top of raw material purity, and not cutting corners when it comes to drying, storage, or transport. Customers who check the specification sheets will see purity levels above 99 percent, but we focus on the performance behind those numbers—smooth crystallization, tightly controlled particle size, and reliable appearance that doesn’t vary from batch to batch.

    Understanding What Sets This Chemical Apart

    Many manufacturers offer a range of dichlorobenzylamines and related intermediates. It’s easy to lose sight of the practical differences between them. In our shop, 3,5-Dichlorobenzylamine distinguishes itself by the position of the chlorine atoms in the benzene ring. This matters in real-world production, since the compound’s reactivity profile and selectivity look quite different from its 2,4- or 2,6-configured cousins. Process engineers know these differences shape the success or failure of downstream reactions—whether they’re synthesizing pharmaceuticals, biocides, or specialty polymers. Subtle changes in starting materials shift yields, switch up side reactions, and alter everything from filtration times to waste treatment.

    The Crucial Role in Fine Chemical Synthesis

    3,5-Dichlorobenzylamine shows up in advanced organic synthesis, serving as a building block where other amines fall short. Customers in pharma and crop protection reach for this compound when seeking controlled reactivity. In bench-scale R&D and pilot trials, chemists often explore alternatives, but once they scale up, they return to 3,5-Dichlorobenzylamine because of its reliable conversion rates and manageable side product profile. We’ve produced batches for everything from pilot kilo-scale runs up to full commercial volumes, so we’ve tracked these success stories firsthand. Synthetic routes that involve nucleophilic substitutions or N-alkylations lean on this amine, since it delivers clean reaction profiles without the pronounced byproduct peaks seen with less well-defined analogs.

    Physical Characteristics Only a Maker Would Notice

    Many product overviews dwell on melting point and molecular weight. From the manufacturing floor’s perspective, what really counts is how the chemical handles under actual plant conditions. 3,5-Dichlorobenzylamine offers a manageable melting range for charging reactors and doesn’t gum up transfer lines under the proper controls. Its slightly hygroscopic nature means we keep an eye on dehumidification and use airtight packaging. Heat stability is solid enough to support multi-hour synthesis runs. Technicians watching the line know to look out for color drift—a sign of potential degradation or contamination in other products, but a non-issue for properly isolated 3,5-Dichlorobenzylamine.

    Safety, Responsible Handling, and Regulatory Considerations

    Producing and shipping this compound under real-world conditions, we see the safety side up close. 3,5-Dichlorobenzylamine falls in a hazard class where dust control and employee PPE matter every day. It demands robust ventilation and filtered packaging systems to keep trace exposure low. Years’ worth of audits and safety evaluations have shaped our current protocols, from fume hood practices to annual refresher training sessions on spill control. Downstream users appreciate this detail because it logs fewer process interruptions due to off-spec or contaminated material. We comply with all the required local and international shipping classifications, based on direct, up-to-date feedback from cargo handlers and regulatory agencies instead of theory alone.

    Comparing Notes with Industry Alternatives

    People who work in the chemical industry rarely accept generic claims. 3,5-Dichlorobenzylamine competes with a thicket of related compounds and substitutes. Some users try 4-chlorobenzylamine or 2,6-dichlorobenzylamine when cost is the only concern, but that rarely works as planned. Our past experience tells us that even tiny variances in molecular structure lead to issues—unwanted isomers, byproduct build-up in columns, and headaches in analytics. Nothing beats a clean, well-made 3,5- isomer for flexible organic synthesis, especially where N-substituted derivatives form the backbone of a finished molecule. Performance in scale-up, reproducibility in output, and ease of downstream workup tend to pull customers back to the product we make, despite the lure of cheaper, less-defined substitutes.

    Responding to Customer Needs in a Shifting Market

    We’ve watched demand patterns shift over the years. Certain processes consume more 3,5-Dichlorobenzylamine during new product launches, particularly in custom agrochemical intermediates. Sometimes price volatility hits, often due to upstream chlorinated benzene availability or global shipping disruption. As a direct manufacturer, we adjust, putting in buffer stock or qualifying secondary raw materials to keep supplies steady. Traders and resellers might fade from sight during market shortages, but we stand by shipments—even if it means pulling weekend shifts to keep commitments. This approach has held up through disruptions caused by holidays, customs changes, or local regulations.

    What Matters Most—Feedback from the Plant Floor and Lab Bench

    Pure chemical analysis and NMR results tell one part of the story. Operators on the production line, the lab chemists on site using our compound in synthesis—these voices shape our practices. Over time, direct feedback informed tweaks to our drying times, bulk packaging weights, and even the way we layer moisture protection for extended storage. Custom packaging sizes came out of these conversations, not marketing focus groups. We learned that working closely with independent QC labs sometimes reveals outlier results others would miss, so we bake extra review steps into our internal testing regime. Customers return for repeat orders because they see batch-on-batch consistency in action, not just on certificates.

    Customization and Supply Assurance—Built from the Inside

    The market for specialty amines draws in new formulas and blends every year. Delivering unique grades, modified particle sizes, or on-time small lot shipments is not just an add-on—we built these capabilities through trial and error. Our reactors and dryers run on demand, not rigid schedules dictated by resellers. If a pharma client requests an ultra-pure, micronized version for a late-stage intermediate, our technical team works out the dehydration and screening tweaks. Frequent updates with our in-house analytical team, as well as client analytical validation, shape the batch release strategy. We keep careful control over our supply chain so last-minute order changes, new packaging shapes, or specific safety labeling gets handled directly, not as an afterthought.

    Tackling the Real-World Challenges of Manufacturing

    Scale-up from grams to tons brings out flaws fast. Years ago, we saw early batches struggle with yield drop-offs due to side reaction formation. Lab protocols often look foolproof, but heat transfer, crystallizer fouling, and batch residence times each bring their own curveballs. Solving these issues meant building experience—knowing which temperature ramps help, how to judge endpoint visually, and why washing protocols matter at the kilo scale. Careful waste stream management grew out of dealing with actual regulator visits and genuine environmental bottlenecks. All of these lessons now roll into the product we send out by the ton or the small pail—so the person at the other end gets more than just a chemical formula.

    Working Together for Safer, Better Supply Chains

    Shipments crossing borders or regions must land on time and intact. We integrate product tracking, transparent customs documentation, and proof of analysis for every lot. Logistics grow tricky when new import rules come into play, especially for chlorinated aromatics. Our logistics team consists of staff who have handled rejected shipments, customs inspections, and all the paperwork in between. Shortcuts in paperwork or packaging never did us favors—so each outgoing shipment matches not just product requirements, but all declared handling and environmental documentation.

    Supporting Research and Development with Trusted Material

    R&D teams in synthetic chemistry often look for small lots to investigate new synthetic routes. We make it a point to offer both commercial bulk and lab-scale samples. University groups and private-sector research chemists have used our batch-supplied material to validate preliminary yields, examine reactivity, and probe mechanism work. Over the years, more than a few patents mention our supplied compound by name. Working with these teams, we see real dialogue about what works and what blocks progress. Adjustments to solubility, purification, or even color matching sometimes appear minor to outsiders, but in our world, these tweaks can launch a new process line.

    Key Observations from Direct Manufacturing

    Daily life on the plant floor teaches patience and precision. Mechanical issues—leaky valves, clogged filters—surfaced in the early years and kept us humble. Batch reproducibility improved only through ongoing investment: better feed pumps, upgraded analytical controls, and smarter feedback loops between the operators, lab staff, and shipping desk. We keep these lessons close, because well-designed production leads to repeat business, not just glossy marketing claims. Our aim remains simple: deliver a 3,5-Dichlorobenzylamine product that adds confidence to every customer using it, whether that’s a pharma synth, a polymer pilot run, or a scale-up in agrochemicals.

    Looking Toward Industry-Wide Improvements

    As new regulatory demands and quality protocols hit the fine chemical sector, we adapt. Some trends look challenging: stricter traceability, expanded safety data, and mandatory sustainability reporting. While competitors sometimes scramble to react, our plant’s direct control lets us shift priorities and equipment schedules. It’s become clear that supply chain transparency and reliable backward traceability will become even more important—not just to meet rules, but to give our downstream partners peace of mind. We are working to integrate digital batch records, quick-response analytics, and real-time logistics updates directly into our workflow.

    Building Trust, One Batch at a Time

    Trust in specialty chemicals doesn’t come through packaging claims or spec sheets alone. We’ve seen how minor shifts in process control—higher ambient humidity, a missed filtration step—can throw off an entire process for a customer. So we own the details. Every kilo of 3,5-Dichlorobenzylamine leaving our facility has the benefit of direct, accountable oversight. Over time, repeat orders and referrals speak for themselves. It all comes back to genuine, day-in and day-out focus on quality, safety, and the relationships built by keeping promises.

    How 3,5-Dichlorobenzylamine Supports Cleaner, More Efficient Downstream Production

    The demand for greener and more efficient chemistry places pressure on supply chains to provide high-purity raw materials. Our approach to 3,5-Dichlorobenzylamine centers on reducing impurities, optimizing crystallization, and minimizing residual solvents—which helps our customers cut down on purification runs, lower waste generation, and tighten their material balances. Feedback from waste treatment managers shows that our material lowers downstream processing costs, since consistent quality means fewer side reactions and less off-spec cleanup. These savings rarely make headline news, but they drive long-term partnerships.

    Ready for Future Collaborations

    As applications evolve, with new pharmaceutical compounds or advanced polymers on the horizon, our commitment to robust, reliable, and responsively supplied 3,5-Dichlorobenzylamine stands unchanged. We invite candid conversations: whether clients are grappling with a new synthetic intermediate, troubleshooting a tricky conversion, or searching for documentation support on audits, our direct experience is always on the table. Keeping open channels—not just between sales and customers, but between chemists, engineers, and plant managers—means the right solution gets put in place from the first trial kilogram to the hundredth ton.

    Why Direct Manufacturing Experience Matters

    Those who manufacture understand why claims on purity and reliability must match real-life performance. With each production run, we stick to a discipline learned by producing 3,5-Dichlorobenzylamine for diverse applications, from bench scale to tonnage. Each improvement we make to our process, each adaptation to market demand, and every bit of feedback from our customers finds its way into the product. This isn’t a matter of chasing certifications. It’s a matter of delivering what works, batch after batch, because real trust comes from direct accountability and experience.