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HS Code |
292708 |
| Cas Number | 35074-77-2 |
| Molecular Formula | C17H25NO |
| Molecular Weight | 259.39 |
| Synonyms | 2-(3,5-di-tert-butyl-4-hydroxyphenyl)acetonitrile |
| Appearance | White to off-white crystalline powder |
| Melting Point | 107-110°C |
| Solubility | Insoluble in water; soluble in organic solvents such as ethanol and acetone |
| Purity | Typically ≥98% |
| Storage Conditions | Store at 2-8°C, protect from light and moisture |
As an accredited 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 25 grams, sealed with a red cap, labeled with chemical name, hazard symbols, and supplier information. |
| Shipping | 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile is shipped in tightly sealed containers to prevent moisture and air exposure. It is transported under ambient temperature, with care to avoid heat, ignition sources, and direct sunlight. Proper labeling and documentation are provided in accordance with chemical transport regulations to ensure safe and compliant handling. |
| Storage | 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile should be stored in a tightly sealed container, protected from light and moisture. Keep in a cool, dry, and well-ventilated place, away from incompatible substances such as strong oxidizers and acids. Store at room temperature or as specified by the manufacturer. Ensure proper labeling and follow all applicable safety and chemical hygiene protocols. |
Applications of 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile in Industrial Manufacturing3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile functions as a specialized hindered phenolic antioxidant intermediate, widely adopted in polymer, lubricant, and adhesive manufacturing sectors. As a direct manufacturer, we supply this raw material to multiple industrial customers who apply it in targeted performance formulations compliant with international standards. The following sections outline principal application scenarios based on extensive supplier experience and verified downstream industry requirements. 1. Polymer Antioxidant Synthesis for PolyolefinsThis material serves as an essential intermediate in the industrial synthesis of high-performance phenolic antioxidants, particularly those used to stabilize polypropylene, polyethylene, and other polyolefin resins. Its integration supports long-term thermal and oxidative stability, critical for consistent processing and end-use product lifespan. Downstream formulators precisely adjust its input depending on resin grade, melt index, and required aging resistance. These applications undergo rigid compliance and batch validation protocols during masterbatch, compounding, and pelletizing processes. Industry compliance standards
Typical usage ratio
Downstream process integration
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2. Lubricant Additive ManufacturingFormulators in industrial and automotive lubricant manufacturing utilize this compound to synthesize high-purity antioxidant agents capable of limiting oxidative degradation in mineral oils, synthetic esters, and polyalphaolefin (PAO) base stocks. Its molecular structure enables process chemists to achieve precise thermal stability and protect engine and hydraulic components under continuous operation and elevated temperatures. Manufacturers strictly observe global lubricant standards, considering additive solubility and volatility for each oil grade or grease formulation. Industry compliance standards
Typical usage ratio
Downstream process integration
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3. Adhesive and Sealant Stabilizer ProductionIndustrial-scale adhesive and sealant manufacturers leverage the compound’s antioxidant profile to improve long-term storage stability and heat resistance of polyurethane, silicone, and epoxy-based formulations. By inhibiting peroxide or radical-induced cure degradation, this raw material, after conversion, enables consistent mechanical and optical properties throughout the adhesive lifecycle. Quality control procedures monitor input ratios closely to comply with cross-linking density and color stability benchmarks, especially for structural bonding and sealant systems. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Synthetic Rubber Anti-Ageing Additive SynthesisManufacturers of synthetic rubbers, especially those focusing on EPDM, SBR, and NBR grades, utilize this material as a precursor for non-staining, low-volatility antioxidant agents essential for automotive, appliance, and cable sheathing compounds. Its use directly supports compounders in meeting specifications for ozone, UV, and heat resistance, crucial for elastomer longevity and physical property retention under demanding service conditions. Adjustments in incorporation rates depend on rubber formulation, cross-linking method, and target end-use severity. Industry compliance standards
Typical usage ratio
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5. Polyurethane Foam Stabilizer PrecursorFoam manufacturers deploy this raw material as a crucial building block in specialty antioxidant systems that enhance the oxidative and thermo-oxidative stability of polyurethane flexible and rigid foams. By improving compatibility with polyol and isocyanate components, the resulting antioxidant delivers consistent color, compression set, and aging resistance for finished foams used in demanding automotive, packaging, and furniture applications. Downstream QC enforces exact additive ratios to avoid emission and fogging limit violations in interiors and sealed environments. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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Competitive 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile prices that fit your budget—flexible terms and customized quotes for every order.
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Day in and day out at our synthesis facility, staff members weigh, charge, and blend ingredients that have direct impact on efficiency and product reliability across hundreds of customer sites. Among hundreds of compounds we manufacture, 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile stands out as one of the workhorses for industrial formulation. Known by its chemical formula, C17H25NO, and its characteristic stabilizing action, this compound means business for manufacturers who need robust antioxidant capabilities in their end applications.
Our experience with this molecule began decades ago, meeting the growing demand for polymer stabilizers in both domestic and global markets. It became clear over the years that shifting environments—UV exposure, processing heat, oxygen—could break down plastics fast. That’s where 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile took on its central role. Unlike simple phenolic antioxidants, its unique tert-butyl groups and acetonitrile moiety offer stronger resistance to thermal and oxidative degradation. Our formulation operators often compare it to a "guard dog" in the polymer chain, helping protect long-chain molecules from becoming brittle or discolored.
Our chemists point out that this compound carries two tert-butyl groups at the 3 and 5 positions alongside a nitrile side arm at position 4. This arrangement gives 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile a balanced hydrophobic character and excellent solubility profile in a variety of organic solvents. Contrast that with simple BHT (butylated hydroxytoluene): while BHT offers cost efficiency, it can fall short where higher temperatures or harsher environmental factors come into play. The acetonitrile functionality not only raises resistance but lowers volatility, so finished polymers hold up better during both processing and in-use lifetimes.
Many users ask us about consistency and purity. We run every lot of 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile through strict HPLC and GC testing protocols. Purity averages above 99%, and our typical batch size ranges reflect both specialty and bulk supply needs. Our packaging team ensures the finished product moves in moisture-sealed, tamper-proof containers—minimizing contamination risk during shipping and storage. Over the years, we've found this commitment to lot-to-lot consistency critical, since small fluctuations in additive quality can knock entire production campaigns off balance.
A common issue with basic antioxidants—think ordinary phenols or less-substituted derivatives—is their tendency to volatilize or break down during high-temperature extrusion or injection molding. In our plant, development trials demonstrated that 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile resists decomposition at temperatures reaching 250°C and above. Producers working with engineering plastics, polyethylene, or polypropylene keep returning because the material keeps their lines running with fewer interruptions for quality control. Fewer burnt spots, less yellowing, and reliably long shelf life show up at the QC station every time this stabilizer gets included in the base resin blend.
The market houses a diverse array of polymer systems, many with their own quirks. From polyoxymethylene to polystyrene, our data and customer experience demonstrate that 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile blends in smoothly without causing haze, gelling, or bleedout problems. Our knowledge base grew out of troubleshooting with compounders who faced migratory stabilizer issues from cheaper antioxidants. We’ve heard stories where, after switching, they gained not only better dispersion but also passed accelerated aging tests with flying colors.
In the niche field of synthetic lubricants, this antioxidant has carved out its place as a trusted solution for base oil stabilization. Unlike more water-sensitive options on the market, it tolerates incidental moisture without breaking down or depositing sticky residues. Our customers in compressor oils and specialty greases have found measurable improvement in service intervals once their formulas were updated to include our material.
One quality control manager from an automotive component manufacturer described fewer returns due to discoloration and embrittlement once their supplier began blending in our antioxidant, replacing raw materials that could not tolerate high heat cycles. Another polymer chemist from a cable insulation plant found that longer weathering performance in outdoor applications secured new contracts for their product line.
Some batch operators in Asia relayed stories of how older stabilizers condensed out during film extrusion, leaving streaks and rejecting finished rolls, yet switching to 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile cleaned up dozens of runs. This direct field-level performance feedback has shaped our ongoing investment in improving process controls and scaling up to meet surging demand.
Our plant’s layout and instrumentation reflect extensive real-world learning from over a decade in active synthesis. Each synthesis step—alkylation, condensation, recrystallization—operates under continuous direct supervision. Operators monitor pH, temperature, and reactant feed rates to safeguard spectroscopic and chromatographic profiles that match target material performance. We do not release batches until blending, drying, and sieving steps check out at every critical control point.
Where some market suppliers cut corners with recycled solvent or off-spec reactants, we’ve maintained a strict raw material acceptance scheme. Paperwork, supplier QC data, and chain-of-custody records all pass through our in-house lab. Not every manufacturer puts boots on the ground along the raw chemical supply chain—yet in our experience, the payoff comes in fewer surprises and less downtime for customers.
Comparing 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile to standard one-ring phenolic antioxidants, the differences hit at both processing and end-use. Our product manages dynamic exposure—think repeated heating, open airflow, or photo-aging—far better due to its molecular bulk and steric hindrance. This means more resistance to oxidation chain reactions and fewer free radicals in finished materials. Simple antioxidants often struggle to match this grade’s stability, particularly once the actual manufacturing environment puts heat and pressure to the test.
In third-party comparisons against less substituted phenolics or even multi-functional thioesters, our product continually scored better for color retention, mechanical resilience, and migration resistance. Material scientists who evaluate stabilizer residues through migration and extractability tests routinely confirm deeper polymer integration. These findings didn’t just come from literature—they came from production samples cycled through real plants, extrusion lines, and end-user applications. The verdict? More reliable performance for customers counting on their materials to survive extended stress.
The debate around antioxidants often touches on safety and environmental persistence. Our production aligns with regulatory expectations for polymer additive ingredients in major global markets. We source all raw intermediates in compliance with prevailing laws and maintain close communication with environmental health experts to keep our material support documentation up to date.
End users working in food packaging or sensitive consumer goods bring forward legitimate concerns about additive migration and human exposure. Our analytical lab runs routine extractability, heavy metal, and residue content checks. By focusing on high purity, we support customer needs for transparency and traceability. Technical representatives frequently consult with downstream users to set realistic migration modeling and support end-to-end material stewardship.
As demand spikes and customer expectations grow more nuanced, continuous investment and R&D become non-negotiable. We recently expanded our purification and finishing lines to unlock larger batch sizes, reduce lead times, and cut down the risk of contamination that can creep in from using undersized vessels or older transfer equipment. Production staff get advanced training not only for instrument operation but for critical troubleshooting—reducing waste and supporting sustainability goals in parallel.
New applications for 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile keep emerging—whether as a stabilizer in biodegradable polymers, a booster for high-performance lubricants, or a specialty additive in coatings and adhesives. Fielding requests from end-users, formulators, and researchers, our technical team uses real trial data to recommend dosing strategies and synergistic blends, helping customers find value beyond the basic molecular profile.
The chemical industry sits at the intersection of regulatory change, customer innovation, and relentless cost pressure. New government directives or shifts in compliance requirements force all manufacturers to adapt quickly. We learned the hard way that investing in compliance—from process documentation to staff certification—builds the trust our partners expect, especially as traceability and global supply chain scrutiny rise.
Protecting finished polymers and lubricants from oxidation isn’t just a matter of inputting the right stabilizer. It demands active process management: quality control, technical troubleshooting, customer feedback loops, and ongoing R&D. Each lot of 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile that leaves our warehouse carries the experience and diligence of a team committed to delivering more than commodity performance—guarding our customer brands against avoidable failure and shelf-life limitations.
Supply chain disruptions, raw material fluctuations, and environmental concerns weigh heavy on all manufacturers. We invest in logistics planning, risk mitigation, and end-to-end transparency. Batch traceability, customer problem-solving, and technical resources all contribute to resilience, securing the reputation of both our own business and those of our end-users—whether their products hit the market in Asia, Europe, or the Americas.
Real partnerships move beyond transaction. We often visit customer plants to review formulation challenges, support switch-over trials, and learn first-hand about bottlenecks or failures. Sometimes we solve problems at the shop floor; other times, solutions come through direct engagement with R&D labs or process engineers. Field observations feed back into manufacturing, guiding process tweaks or changes in fine purification steps that unlock better ease of use for everyone involved.
Staying current with industry certification and safety standards does not end at routine internal audits. Our teams attend technical seminars, keep up with journals, and invest in collaborations with research institutes. While plant operators perfect run-to-run reliability, development chemists hunt for process improvement, new synergies, and value added by small tweaks in formulation. Customer problems are our source for innovation, as real-world performance lives and dies by the quality of the stabilizers inside finished parts.
Supporting technical training for our distributors, partners, and end-users pays off as well. Providing application guidance for migrating from legacy antioxidants, documenting success stories, and troubleshooting blends that don’t deliver builds a knowledge network that benefits everyone in the value chain. It’s this commitment to shared expertise and two-way information that sets manufacturers apart from mere suppliers.
Plant operators and material processors increasingly require more than technical grade or commodity stabilizers—they demand material consistency, reliable performance, and honest support for troubleshooting. Raw materials like 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile answer those demands only if the manufacturer continues to invest in quality improvement, technical training, and customer engagement. We have built our business not only on the ability to synthesize this compound efficiently, but also on the capacity to listen, adapt, and deliver on evolving application needs.
Many sectors—from cable jackets to synthetic lubricants, specialty adhesives to modified polyolefins—lean heavily on high-quality antioxidant additives. As polymer blends grow more advanced and market standards rise, subtle differences in synthesis, purification, or supply can decide future business. We see emerging demand for stabilizers that tolerate harsh compounding, maintain color and mechanical integrity, and do not compromise health or safety profiles. That’s the challenge our product engineering and customer service divisions work to meet with each metric ton shipped.
The story of 3,5-Di-Tert-Butyl-4-Hydroxyphenylacetonitrile at our company is more than a list of chemical features. Its value takes shape in extrusion halls, on production lines, in maintenance logs, and in countless feedback loops with customers. The technical and field teams see—every day—how molecular differences translate into uptime, shelf life, and end-user confidence. Continuous improvement only happens through honest engagement with every challenge, whether it’s formulation drift, regulatory shifts, or customer innovation.
Across industries, one lesson stays the same: it’s the combination of right material and right support that allows companies to meet performance, safety, and sustainability commitments. Every drum or bag of stabilizer we produce serves as an invitation for our customers to share their challenges. Those partnerships—rooted in real-world insight, technical rigor, and daily communication—form the backbone of our promise as a manufacturer of high-performance chemical additives.