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HS Code |
392858 |
| Cas Number | 3846-73-7 |
| Molecular Formula | C5H2Cl3NO |
| Molecular Weight | 196.44 g/mol |
| Iupac Name | 3,5,6-trichloropyridin-2-ol |
| Appearance | White to off-white crystalline solid |
| Melting Point | 140-144°C |
| Boiling Point | 325°C (decomposes) |
| Solubility In Water | Moderately soluble |
| Density | 1.66 g/cm³ |
| Flash Point | 183°C |
| Synonyms | TCP; 2-Pyridinol, 3,5,6-trichloro- |
| Odor | Odorless |
| Pka | 6.1 (approximate) |
| Logp | 2.63 |
| Stability | Stable under normal conditions |
As an accredited 3,5,6-Trichloro-2-Pyridinol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White powder, 250g net, sealed in amber glass bottle with tamper-evident cap; labelled as "3,5,6-Trichloro-2-Pyridinol, ≥98% purity." |
| Shipping | 3,5,6-Trichloro-2-Pyridinol should be shipped in tightly sealed containers, protected from moisture and direct sunlight. It must be labeled as a hazardous material and handled according to relevant regulations. Store and transport at room temperature, ensuring containment to prevent leaks or spills and using appropriate personal protective equipment (PPE) during handling. |
| Storage | 3,5,6-Trichloro-2-Pyridinol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Protect from moisture and direct sunlight. Store at room temperature and label the container clearly. Ensure proper personal protective equipment is used when handling to prevent inhalation, ingestion, or skin contact. |
Applications of 3,5,6-Trichloro-2-Pyridinol in Industrial Manufacturing3,5,6-Trichloro-2-Pyridinol serves as a core intermediate for several downstream chemical industries. As a direct manufacturer, we supply this key raw material to sectors with dedicated production protocols, specific technical requirements, and well-defined regulatory controls. Below we detail the principal industrial applications, focusing on formulation, integration points, compliance criteria, and real-world finished products. 1. Agricultural Chemical Synthesis: Herbicide IntermediateThe compound functions as a critical building block in the synthesis of selective herbicides, especially in the triazine class. Manufacturers incorporate it during chlorination and coupling steps that form the active agent in advanced weed control formulations. It is indispensable for firms producing pre- and post-emergent herbicides, where purity and controlled reactivity determine downstream product quality. Industry compliance standards
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2. Public Health and Hygiene: Antimicrobial Active IngredientDownstream manufacturers in the disinfectant and sanitation sector use the compound as a precursor for producing broad-spectrum antimicrobial agents in institutional and public health products. Chlorination reactions involving this intermediate yield active species, especially for water treatment and surface sanitizers, requiring stringent control of residual contents and consistent batch traceability. Industry compliance standards
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3. Pharmaceutical Intermediate: Synthesis of Veterinary ActivesThe compound is processed by veterinary pharmaceutical manufacturers for active pharmaceutical ingredient (API) synthesis targeting antiparasitic and antimicrobial drugs for animal health. Integrated under CGMP environments, it acts as a chloroarene core for subsequent heterocyclic coupling and protection-deprotection reactions in multi-step syntheses. Industry compliance standards
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4. Wood Protection Chemicals: Fungicide and Preservative PrecursorIndustry specialists producing wood protective coatings and preservatives use this molecule to synthesize fungicidal agents designed for high-durability timber processing. Incorporated in formulating actives with proven resistance to wet rot and surface microbial growth, it supports safer, longer-lasting construction and outdoor wood installations. Industry compliance standards
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5. Specialty Chemical Catalysis: Halogenated Pyridine Derivative SynthesisSpecialty chemicals manufacturers utilize the compound as a halogenated pyridine platform for catalyst ligands, corrosion inhibitors, and other advanced fine chemical derivatives. It enters as a reactive intermediate, especially in cross-coupling processes requiring precise regiochemical control and high halogen content to enable downstream selectivity in functionalization. Industry compliance standards
Typical usage ratio
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Competitive 3,5,6-Trichloro-2-Pyridinol prices that fit your budget—flexible terms and customized quotes for every order.
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Working over two decades with pyridinols, we have seen the unique quirks and challenges that come with synthesizing and scaling up 3,5,6-Trichloro-2-Pyridinol. Each batch begins with careful handling of precursor chlorinated pyridines in reactors designed for both safety and flexibility. The product you buy starts long before a drum or bag leaves the plant. Careful attention in every kilo we make drives its reliability for formulators who need consistent quality. Many of our long-term clients in pesticide production, especially for herbicide and insecticide intermediates, demand purity and elemental balance they can measure every time. The slightest deviation can trip up downstream yields or process safety, so we tune our reactors, purify through custom distillation trains, and test until the product profile matches the rigid internal benchmarks we’ve built up over years.
Chlorinated pyridinols behave differently from simpler aromatics, and this one brings its own signature. With three chlorine atoms at the 3, 5, and 6 positions, this molecule resists many side reactions during downstream applications. We structure production routines to ensure a balance: maximum chlorination, low residual starting materials, and a product with clear, off-white appearance. Not every synthetic route delivers the same ratio of isomers or contaminant profile, and our team worked out analytical methods that help us tune crystal purity and avoid unwanted color bodies. Our years managing this process help keep the product in spec, even as different seasons and feedstock sources roll through.
Our current model of 3,5,6-Trichloro-2-Pyridinol, sometimes referenced by the industry shorthand TCP, is available as a technical grade suitable for industrial synthesis. You won’t find a one-size-fits-all here. We keep purity at 99% minimum by HPLC, moisture below 0.3%, and maximum residual solvents determined by client application. Unlike resellers who might repackage or mix lots, all batches originate from our own continuous system.
Standard packaging involves lined fiber drums, but for clients requiring smaller charging or automated loading, we can transition to heavier-duty HDPE bins. We've learned that minimizing headspace and maintaining low humidity preserves the appearance and flow properties for months in storage. Cases of clumping or discoloration reported by downstream users almost always point to breaks in the supply chain or mishandling during transit — not issues we see leaving our facility under the right protocol.
Formulators rely on 3,5,6-Trichloro-2-Pyridinol as a key starting material for creating selective herbicides and certain organophosphate insecticides. One popular route uses it as a core building block in the synthesis of chlorpyrifos and other complex molecules where the chloro pattern matters. The hydroxyl group on the pyridine ring opens up further derivatization without unpredictable side reactions. In pesticide applications, a shift in quality or byproduct levels can spell millions in lost product yield. For custom chemistry labs or multinational agrochemical companies, there’s little margin for inconsistent intermediates.
Because the molecule is both an intermediate and a useful analytical reference, quality at this stage controls downstream outcomes. Processes that rely on this material often run for weeks, so any dropout in purity or introduction of certain nitrosamines can create regulatory hurdles or halt production. As manufacturers, we’ve built checks at every stage, supported by both batch and continuous analysis, to make sure nothing out of spec moves forward. The rate of technical complaints from our facility remains among the lowest in peer comparison, a point we've worked hard to maintain in both domestic and export contracts.
Every batch of 3,5,6-Trichloro-2-Pyridinol that comes off our reactors tells a story about the flexibility — and sometimes stubbornness — of chemical engineering at scale. In practical terms, the compound can cake or bridge in humid air, especially on rainy days in spring and autumn. To minimize these issues, our storage area holds strict temperature and moisture control. Staff working at packaging lines move drums within hours of sealing and use flush nitrogen to keep oxidation and hydrolysis at bay. We don’t leave product in open bins or unprotected from the environment. Loss to atmospheric moisture or cross-contamination not only degrades purity but frustrates everyone who invested hours in getting the synthesis right.
On more than one occasion, we have worked directly with technical teams from major agrochemical firms to adjust our particle sizing or change the way we vacuum-pack the final product. These small adjustments often make the difference between a product that flows easily during automated charging and one that snags on every conveyor. Such feedback cycles — and the iterative fixes we make in response — drive continuous improvement. Our teams track data by lot and regularly survey clients about downstream performance, not just initial purity.
Some buyers might think all lots of 3,5,6-Trichloro-2-Pyridinol are alike, but our years in manufacturing have put that idea to rest. Smaller synthesis shops can’t always control elemental impurities at trace levels. While these might not show up in standard QC, they surface during downstream synthesis or environmental release tests. Our in-house labs track halide patterns, heavy metals, and residual solvents well below typical regulatory cutoffs.
Another distinction comes in scale. We have invested in supply chain resilience, so backorders or feedstock volatility rarely interfere with contract obligations. During the last global logistics disruption, competitors openly rationed stock and delayed shipments. By comparison, our clients maintained steady production because we pre-stocked key inputs and committed to buffer inventory in dedicated warehouses. For buyers who lock in annual contracts, this translates into stable pricing and less downtime.
Some clients ask about product grades beyond technical – such as extra-fine or low-dust forms. We can deliver custom sieving, but we always caution that changes to particle properties must match application needs. Not every new physical tweak improves actual production. We’ve seen cases where ultra-fine powder plugged process lines or created handling headaches. For most users, our base technical grade solves the daily needs of blending, dissolution, or controlled feed to reactors.
On the regulatory front, our record of compliance with handling and disposal rules stands up to external scrutiny. The chlorinated nature and persistent character of the molecule require careful stewardship, and our operations team holds regular audits alongside national and regional agencies. While not all producers disclose environmental mitigation practices, we build that into process design from the start — investing in fume abatement, solvent recovery, and staff training to keep both product and people safe.
Pesticide developers and researchers at synthesis labs have shared pain points with sourcing inconsistent material. Off-grade imports, for example, may include residual monochloro or dichloropyridines, introducing off-flavors, reactor fouling, or waste disposal issues. Over time, formulation scientists have learned to check their supplies early in the process, saving hundreds of hours in troubleshooting by pinpointing deviations at the source rather than midproduction.
Alongside technical control, product stewardship shapes practical use. We invest in detailed knowledge transfer with factory clients, helping bridge the gap between chemical supply and production challenges. Sometimes this means sending technical staff for onsite troubleshooting. Other times, it involves creating detailed handling guides or reviewing procedures at customer sites. We have seen other manufacturers treat this type of product as just another commodity — a recipe for frustration in specialty applications.
We encourage users to work with us on custom storage and dosing solutions. Adding desiccant, selecting the right drum lining, or recalibrating auger feed rates can all extend shelf life or improve throughput. These are common sense fixes that carry real economic benefit. Each step represents a layer of reliability — something we sweat over in our own plants, and which pays off across the value chain.
The feedback loop between our plant and our clients’ process lines shapes the way we improve batch after batch. Tracking these collaborative fixes over several years, we’ve shrunk downtime, trimmed raw material wastage, and kept product recalls to a rare occurrence. In a world where every delay or rework counts against productivity and cost structure, these small operational gains make a real difference.
Demand for 3,5,6-Trichloro-2-Pyridinol continues to track with both global agricultural trends and efforts to tighten chemical regulation. Recent years brought wider scrutiny of impurity profiles, sustainable sourcing, and transporter safety in major supply contracts. We invested in analytical upgrades and independent third-party audits not to win awards, but to keep an edge in markets that punish inconsistency.
Changing regulatory landscapes sometimes force tighter controls on impurity classes or shipment labeling. For example, countries expanding environmental monitoring flag any non-compliance with trace halogenated organics. Because we run our entire workflow under transparent process controls, adapting to new standards takes weeks, not months.
The shift toward more sustainable agrochemicals also encourages buyers to look upstream, questioning not just price and purity but lifecycle impact and byproduct management. We field more technical questionnaires than ever from global clients, intent on tracking every aspect of the intermediate’s footprint. As a manufacturer, direct answers come easily — our data isn’t filtered through a chain of resellers, and our process improvements go straight into the product, not just the paperwork.
For those wondering about price stability, we point to investments in scrubbers, waste minimization technology, and feedstock controls. These keep externalities in check and help us offer contract stability over multi-year agreements. While market pricing still swings with global trends, our track record shows smaller spikes and fewer force majeures than other producers relying on “spot” or off-spec blending.
No chemical process reaches perfection, and we openly acknowledge the obstacles along the way. Sourcing high-purity chlorinated feedstocks in tight demand seasons puts pressure upstream. Where some would cut corners, we opt for locking in long-term contracts and qualifying multiple suppliers.
Waste stream management around chlorinated intermediates also raises persistent challenges. We double down on solvent recovery and work through routine process audits. Beyond regulatory compliance, minimizing chlorinated waste carries practical benefits: it keeps operational costs lower and reassures clients facing their own regulatory reviews.
Process safety remains central, especially with the persistent toxicity of pyridinols and their derivatives. Our training programs, engineering controls, and emergency response setups aren’t optional — they are integral to steady output and the kind of supply reliability that clients count on. We retain experienced engineers and chemists, not only to hit production targets but to innovate new purification routes, troubleshoot at scale, and respond quickly to client demands as regulations or final product requirements shift.
Direct experience shapes every aspect of how we produce and supply 3,5,6-Trichloro-2-Pyridinol. Unlike trading houses or independent distributors, we own the process, from raw input all the way to loading dock. This means fewer surprises for downstream users, less hidden variation in lot-to-lot quality, and a level of support that stems from actually making — not just moving — chemical goods.
Engineers on our team routinely analyze real-world failures, sharing insights into why certain impurity spikes or handling problems occur. That granular knowledge turns into process tweaks, manufacturing upgrades, or customer training sessions. Mistakes make for better operators, and every challenging batch deepens our understanding of the product’s personality.
We work with users who value transparency and technical partnership. Open dialogue about product fit, risk management, and innovation drives collaborative solutions. Our goal is to keep improving so each client draws maximum value from their investment, whether formulating legacy compounds or researching next-generation chemistries.
Whether feeding high-capacity reactors for crop protection or testing small-batch syntheses in the lab, users of 3,5,6-Trichloro-2-Pyridinol benefit from products built on deep process knowledge and stubborn attention to detail. Our offering stands out not just for chemical purity but for the combined expertise and technical foresight behind every drum. Clients approach us with new requirements, critical constraints, and process improvements. We treat those as the sparks that drive industry forward.
While technical specifications matter, real value comes from the cumulative experience rolled into every production run, every batch note, every support exchange. That’s the difference our team brings to the table for users who need a chlorinated intermediate that delivers reliability under real manufacturing conditions.
No batch leaves our plant without a full review and confidence in its performance. Our customers know the difference because we hear back from them after every successful campaign, and from the rare hiccup that exposes needs for further innovation. In a changing marketplace, anchored by shifting regulations, global demand, and a push toward more responsible production, we believe manufacturing leadership comes from this persistent cycle of improvement and hands-on collaboration.