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3,4-Dinitroaniline

    • Product Name 3,4-Dinitroaniline
    • Alias m-Dinitroaniline
    • Einecs 203-568-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    966051

    Chemicalname 3,4-Dinitroaniline
    Molecularformula C6H5N3O4
    Molarmass 183.12 g/mol
    Casnumber 610-21-3
    Appearance Yellow crystalline solid
    Meltingpoint 169-171 °C
    Boilingpoint Decomposes before boiling
    Solubilityinwater Slightly soluble
    Density 1.599 g/cm³
    Pubchemcid 12448
    Smiles CC1=CC(=C(C=C1N)[N+](=O)[O-])[N+](=O)[O-]
    Synonyms 3,4-Dinitrobenzenamine
    Odor No significant odor
    Stability Stable under recommended storage conditions

    As an accredited 3,4-Dinitroaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100-gram amber glass bottle with a secure screw cap, labeled "3,4-Dinitroaniline," hazard symbols, and handling instructions.
    Shipping 3,4-Dinitroaniline should be shipped in secure, tightly sealed containers, clearly labeled as hazardous. The chemical is sensitive to heat and shock, so transport within compliance of regulations for toxic and potentially explosive solids is required. Shipping must follow UN 2229, class 6.1 (toxic) guidelines, with appropriate documentation and safety data provided.
    Storage 3,4-Dinitroaniline should be stored in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible materials such as strong oxidizers and reducing agents. Keep the container tightly closed and clearly labeled. Store it in a tightly-sealed, corrosion-resistant container, placed in a designated chemical storage cabinet to prevent environmental contamination and ensure safe handling.
    Application of 3,4-Dinitroaniline

    Applications of 3,4-Dinitroaniline in Industrial Manufacturing

    As a direct manufacturer, we supply 3,4-Dinitroaniline (3,4-DNA) to established global sectors, all driven by proven chemistry integration. The following application areas demonstrate its critical downstream roles, governed by sector-specific compliance, proven formulation ratios, defined process points, and resulting in tangible end-use products relied upon by industry leaders.

    1. Agrochemical Synthesis: Herbicide Intermediates

    Producers of selective herbicides use 3,4-Dinitroaniline as a vital building block in the synthesis of dinitroaniline-based herbicide actives, including those targeting grass and broadleaf weed control in commercial agriculture. In these processes, our product undergoes controlled nitration, coupling, and amination stages, determining the efficiency and activity of the final formulation. Integration must consistently meet purity targets to avoid crop phytotoxicity and environmental residue. Specialized usage supports major agrochemical brands formulating for cereal, cotton, and vegetable crops.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products (FAO/WHO)
    • ISO 9001:2015-certified QMS for agrochemical synthesis
    • EU Regulation 1107/2009 (Plant Protection Products Regulation)
    • US EPA Registration for Active Ingredients (40 CFR Part 180)

    Typical usage ratio

    • 0.2–0.8 mol ratio as core intermediate in target synthesis, adjusted for molecular yield and selectivity

    Downstream process integration

    • Added post-nitration to coupling reactors in multi-step synthesis for active herbicide molecules such as pendimethalin, trifluralin, or similar dinitroaniline actives

    Final product types

    • Pre-emergent and selective herbicides in technical concentrate or formulated EC/SC/GR
    • Bulk technical herbicidal APIs

    2. Dye and Pigment Intermediate

    Leading pigment and dyestuff manufacturers incorporate 3,4-Dinitroaniline to synthesize azo, disperse, and sulfur dyes, particularly in colorfast textile, leather, and plastic applications. Its nitro groups introduce unique chromophore properties essential for high-stability colorants. Purity directly influences final dye solubility, heat resistance, and compliance with export textile regulations. Typical use occurs during diazotization and coupling stages, where specific ratios impact batch hue and shade consistency. Our facility supplies tailored grades for deep yellow to orange-red dye synthesis.

    Industry compliance standards

    • Ecological and Toxicological Association of Dyes and Organic Pigments Manufacturers (ETAD) Code of Practice
    • OEKO-TEX Standard 100 textile safety certification
    • REACH compliance for pigments and dyes (EC 1907/2006)
    • GHS hazardous labeling requirements for pigment intermediates

    Typical usage ratio

    • 5–15% by weight in the aromatic amine or diazo compound input; precise ratio tuned for target chroma and solubility

    Downstream process integration

    • Charged as diazo component or amine source during coupling reaction in batch dye synthesis

    Final product types

    • Azo and disperse dyes for textile dyeing
    • Sulfur dyes for cellulosic fibers
    • Organic pigments for plastics and printing inks

    3. Pharmaceutical Synthesis: API Precursors

    Active pharmaceutical ingredient (API) producers utilize this material as a secondary intermediate for synthesizing select nitroaniline-derived molecules, including investigational antitubercular and antimicrobial agents. Stringent particle and residual solvent control prevent contamination downstream. The raw material undergoes reduction and condensation in GMP cleanroom environments, demanding batch release traceability. Microbial, heavy metals, and nitrosamine limits apply to comply with pharmacopoeia mandates. Supply chain traceability and batch-specific documentation are mandatory for regulated markets.

    Industry compliance standards

    • Good Manufacturing Practice (GMP, ICH Q7)
    • European Pharmacopoeia and USP monographs for nitroaniline precursors
    • 21 CFR Parts 210-211 (US FDA drug production and controls)
    • ICH Q3D (Elemental Impurities)

    Typical usage ratio

    • Stoichiometric input based on the specific API scaffold; generally 1–1.2 equivalents per target unit step

    Downstream process integration

    • Reduction or catalytic hydrogenation under controlled GMP conditions, forming amino-intermediates for condensation with other heterocyclic fragments

    Final product types

    • Intermediate-stage pharmaceutical bulk substances
    • Active antimicrobials and nitroaniline-derived APIs

    4. Polymer Additive Production (Antioxidant Precursors)

    Manufacturers of industrial antioxidants select this compound as a precursor to synthetic stabilizers, especially hindered amine light stabilizers (HALS) and nitroaniline-based antioxidants for plastics and synthetic rubber. Its controlled nitration and subsequent alkylation allow downstream producers to tailor molecular weight and stabilization strength. Ratio depends on target antioxidant type and resin compatibility, with traceability for food-contact or automotive plastics. End-application regulations regarding residual nitro compounds are enforced during final compounding.

    Industry compliance standards

    • FDA 21 CFR 177.1810 (Polymers for food contact materials)
    • EU No. 10/2011 (Plastic Materials and Articles Regulation)
    • ISO 9001:2015 for polymer additive production
    • ASTM D6280-18 (Plastics and Rubbers Testing)

    Typical usage ratio

    • 0.5–5% in additive precursors; adjusted based on required effectiveness and final plastic polymer specification

    Downstream process integration

    • Introduced during initial synthesis of stabilizer molecule, prior to compounding or masterbatch formation

    Final product types

    • HALS antioxidants for polyolefins
    • Polymer masterbatches for packaging and automotive components
    • Stabilizer concentrates for synthetic rubber manufactures

    5. Specialty Chemicals: Analytical Reagents

    Producers of analytical agents and lab diagnostics include this material as a primary standard for nitro group recognition and quantification. High-purity grades are critical for calibration solutions and standardization of spectroscopic methods. Usage follows strict laboratory and industrial quality norms, ensuring no interfering residuals. Ratio selection depends on the sensitivity and detection limits required by the analytical procedure, with in-process controls for trace metal and organic impurity content certified by certificate of analysis.

    Industry compliance standards

    • ASTM E200-19 (Standard Practice for Preparation of Analytical Solutions)
    • ISO/IEC 17025 (Testing and Calibration Laboratories)
    • CFR Title 21 Part 58 (GLP for nonclinical labs)
    • Good Laboratory Practice (GLP)

    Typical usage ratio

    • Prepared as 0.01–1% calibration solution, ratio defined by method sensitivity and analytical protocol

    Downstream process integration

    • Dissolved in solvent matrix for reagent-grade calibration standards; introduced into analytical testing kits

    Final product types

    • Spectrophotometric and colorimetric calibration solutions
    • Reference standards for laboratory analysis
    • Chemical analytical test kits for nitro aromatic quantification

    6. Explosives and Propellant Intermediates

    Defense and specialty pyrotechnics manufacturers use 3,4-Dinitroaniline as a functionalized precursor in the controlled synthesis of certain specialty explosives and propellant modifiers. Its introduction must adhere to strict handling and batch documentation under national defense regulations. Downstream synthesis typically involves controlled amination or condensation stages under elevated precautions. Formulation ratios are dictated by energetic yield and detonation sensitivity, with batch records and chain of custody required for all shipments.

    Industry compliance standards

    • UN Recommendations on the Transport of Dangerous Goods
    • US ATF explosives manufacturing guidelines
    • EU Regulation (EC) No. 1907/2006 – Annex XVII (Restricted Chemicals in Explosives)
    • ISO 2230 (Explosives and Pyrotechnics: Storage and Handling)

    Typical usage ratio

    • 5–15% as intermediate; final ratio set by output energy, formulation restrictions, and safety margin testing

    Downstream process integration

    • Charged during key step in explosive base structure assembly; processed prior to blending in main charge or propellant system

    Final product types

    • Specialty explosive modifiers for commercial mining
    • Military-grade propellant additives
    • Pyrotechnic initiator compounds
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    Certification & Compliance
    More Introduction

    Direct from the Source: An Honest Look at 3,4-Dinitroaniline

    Experience Forged by Hands-On Chemical Production

    Decades in the industry have shown me that quality and consistency don’t start on the shelf or in a warehouse. They begin inside the reactor — and not just any reactor, but in facilities where each process is tightly controlled and continuously monitored by people who know the difference between adequate and excellent. 3,4-Dinitroaniline stands out among aromatic nitro compounds for its stability and performance profile, characteristics we’ve confirmed and refined through every stage from raw feedstock to finished product. Our experience is rooted not in trading, but making — putting product through its paces at every turn so no surprise waits downstream.

    Getting to Know 3,4-Dinitroaniline

    Ask anyone who has worked the vats: a batch of 3,4-Dinitroaniline isn’t just another commodity. This compound brings a set of attributes that experienced manufacturers and end-users count on. Clear yellow crystalline appearance tells a first story, but the deeper value reveals itself in what happens during application. Chemical purity, particle size, and residual moisture make a real-world difference. For us, these aren't abstract metrics; they’re the fundamentals that drive safe storage and reproducible results.

    Throughout our production line, 3,4-Dinitroaniline is usually supplied in technical grade — high purity to match industrial standards, suitable for synthesis and specialty formulations. Typical melting points hold tight to established ranges, a sign that the process and raw inputs do their job. Analytical checks on every lot screen out anomalies before they matter. Where possible, we push for lower levels of related impurities, because contamination can complicate downstream synthesis or alter how the compound reacts under load.

    Real Uses, Real Work: How 3,4-Dinitroaniline Is Applied

    Many of our industrial partners turn to this material for its value in advanced synthesis. Most commonly, 3,4-Dinitroaniline serves as a precursor in producing herbicides, azo dyes, specialty pigments, and intermediates where the placement of nitro groups defines reactivity. Among other aniline derivatives, this one gives a consistent backbone for building more complex molecules. The formation of stable linkages depends on purity and crystal form; a poorly controlled batch doesn’t just slow things down, it throws off entire process economies.

    Different people have asked what sets this compound apart from alternatives. Take ortho or para substituted dinitroanilines as examples — their physical forms, melting points, and reactivity profiles can divert sharply from those of 3,4-Dinitroaniline. Imagine trying to substitute a 2,4-dinitroaniline when precise coupling reactions are needed; the outcome can fall short because the electron distribution and steric profile shift. In contrast, a consistent supply of our 3,4-structured material lets manufacturers avoid costly reformulation and repeated trials. We recognize these details because we face them on the floor, not just on paper.

    Manufacturing Integrity: From Bulk to Finished Package

    We approach 3,4-Dinitroaniline production as an end-to-end responsibility, beginning with feedstock integrity. Nitration processes involve tight temperature and pH controls, which affect yield quality and impact the scale of secondary by-products. Our staff has run enough campaigns to spot deviations before they become failures; we reject batches that don’t track to spec, because a shortcut at our end just grows into a bigger problem down the chain.

    Once synthesized, the material undergoes controlled crystallization and solid-liquid separation. Agglomerate formation, dusting, and fine particle fractions are closely monitored. Operators know any excess fines slow handling and drive losses before the process even reaches the filter dryers. Product moves to specialized drying stations where moisture is carefully pulled down to minimize risk of caking or microbial growth in storage. The hands involved aren’t just following a checklist; they know what to watch for because the cost of getting it wrong is more than paperwork — it’s credibility lost.

    Bulk storage tanks and packaging lines run under controlled ambient conditions to reduce risk of decomposition. Packing teams, familiar with the subtle signals of proper crystallization, reject off-color or unusual texture. Packaging into sealed containers prevents loss from abrasion and keeps out moisture. We don’t farm this out to third parties — every stage stays under our roof, accountable to our reputation. It’s not uncommon to spot us reviewing drums after labeling, agitating for feedback from our own team rather than waiting for reports from a distant distributor.

    Working Alongside Industry: Not Just a Middleman

    Unlike traders, our relationship with downstream users isn’t superficial. We stand beside formulators and R&D groups tackling process development, troubleshooting, and scale-up. Chemists at specialty chemical groups have visited our floor to see post-synthesis purification first-hand, sometimes asking for minor tweaks in particle size to fit their process lines. They’ve seen that questions on reproducibility aren’t shrugged off. If an application needs micro-size adjustment or tighter impurity windows, we talk through feasibility in direct terms, drawing from plant logs and live production data.

    Our own chemists remain involved in supporting customer evaluation, walking through application studies, not just handing over a sheet of numbers. If a pigment house needs to explore the subtleties in fastness or solubility, we’re prepared to share methods we’ve used in our own QC labs. Sometimes the feedback reveals opportunities — a suggestion to further cut trace aniline impurity led us to recalibrate a purification step. This direct feedback loop rarely holds up in trading; only the manufacturer sees the full scope and can actually pivot the process in meaningful ways.

    Comparing to the Competition: A Practical Perspective

    It’s tempting to treat aromatic nitro compounds as all the same, but years on the job teach otherwise. Some producers stretch cycle times or relax on intermediate purification, cutting overhead per kilogram. This might pass casual inspection, but real process work exposes the difference: inconsistent melt behavior, trace color, or small changes in reactivity begin to show in real application trials. Our operation maintains batch records spanning back decades, and time spent reviewing customer returns points to a clear pattern — tighter QC at the point of manufacture directly cuts downstream problems.

    Differences extend past purity. Batch-to-batch consistency in crystal habit, to cite one example, has real consequences in blending, slurry formation, or metering in continuous systems. One pigment customer documented annual cost savings after switching to our grade, citing lower screen blockage and fewer halts for filter cleaning. Our in-house process engineers see this as validation of attention to particle morphology, not just chemical analysis. There’s no way for a mere trader to influence this level of production nuance.

    We’ve also encountered user requests attempting to replace 3,4-Dinitroaniline with other dinitroanilines — searching for cost savings, or because of supply gaps. Usually, the change results in lower output, unpredictable by-products, or even equipment fouling from particles out of size spec. We advise carefully reviewing the structure-performance relationship before making any swap. Our database of case reports includes dozens of such unsuccessful attempts, a resource we share in technical dialog to help our customers avoid repeating old mistakes.

    Quality Control: Lifting the Veil

    Good product isn’t magic. You arrive at it through a sequence of controlled steps, verified by a QC program that can’t take shortcuts. Our approach is rooted in full traceability. Each lot receives a full panel of tests: chemical purity by chromatography, trace by-products by advanced spectrometry, particle size checks, and moisture balance out to the decimal. Because 3,4-Dinitroaniline serves as a building block in so many sensitive applications, undetected side-products in a batch mean wasted time and money for users on the receiving end.

    Our staff is trained not only to perform analytical routines but to interpret anomalies and challenge results that don’t feel right. For example, our operators track color shift at the point of packaging, flagging even minor departures from standard yellow. A chemical might technically pass spec, but our experience tells us certain color changes can hint at underlying contamination or by-product issues. Acting at this level of attention isn’t about box-ticking; it’s about standing behind our commitments to users who put real trust in their supplier relationships.

    Materials Handling: Addressing Practical Risks

    3,4-Dinitroaniline, in high concentration and quantity, poses certain risks: dust inhalation, possible sensitization, and environmental hazards if mishandled. From the early days, we realized relying on generic material safety protocols was not enough. We operate dedicated containment and extraction systems in areas where fine dust could form. Production and packing crews receive practical training, reinforced by drills, so reaction time is sharp if a spill or exposure ever occurs.

    Our storage practices include temperature- and humidity-controlled rooms, managed by staff who check physical condition weekly. We log not only compliance data but trends on lot condition — it gives us more lead time if a control needs tuning. Customers sometimes expect generic packaging, but we use high-barrier liners and sealed drums to block out moisture and prevent oxidation. Our decision isn’t about chasing standards for their own sake; it’s a response to real-life spoilage events in the early years, lessons learned sometimes the hard way.

    Addressing Regulations and Market Demands

    Regulatory requirements for aromatic nitro compounds, especially in certain jurisdictions, have tightened over time. Direct experience with audits and registration keeps us on alert. Documentation of origin, chain of custody, and proof of responsible production isn’t a luxury— it’s a barrier for market access. Our plant runs under multiple harmonized standards, and the staff assigned to compliance are chemists, not just administrators. If a market changes its registration obligations, we adjust data reporting and process documentation in real time, never waiting to be caught flat-footed by shifts in supervision.

    End-users notice more than certificates. Confidence grows when they review our audit trails, batch records, and access to live production data — not sanitized summaries. This depth of transparency builds more meaningful trust than any labelling claim. On-site inspections aren’t rare, and we open processes up to review. Direct handling of queries from regulators or customers has taught our commercial staff that real answers beat rehearsed talking points. We hold to that ethic because it’s what built our working relationships in the first place.

    Problem-Solving: Not Every Day Runs Smooth

    Long experience tells us that even proven processes sometimes veer off expectation. We’ve met flares of unknown by-products, sudden supply constraints, and unexpected customer challenges. Surging demand can put pressure on capacity, yet compromising standards never works in the long run. We respond by building buffer stock, documenting alternate routes for synthesis and packing, and maintaining well-drilled teams ready to add shifts when needed. We’ve invested in in-house troubleshooting, from laboratory to plant, so when an out-of-spec result pops up, feedback reaches process engineers without delay.

    Working in close contact with the real material offers perspective unavailable from secondary suppliers. For example, issues in downstream coupling or dye shade have prompted us to work backward through plant records, isolate the production window, and recover the suspected lots. Sometimes the remedy lies in talking face-to-face with the end-user's engineers, iterating through sampling, and making labeled test batches rather than just theorizing from afar. This is only possible through owning the full production chain from raw to finished.

    Toward Sustainable and Responsible Manufacturing

    Disposal and environmental release of 3,4-Dinitroaniline waste streams carries strict oversight. In running our own facility, we treat effluent and solid residuals using established chemical destruction methods. We’ve tested neutralization, incineration, and secondary chemical degradation to minimize offsite disposal. Periodic technology reviews let us trial improved abatement systems, aiming for reductions in off-gases and liquid contaminants. Employees have a real stake in site health, and strong environmental stewardship is the bedrock on which we operate — as returns audits make clear, shortcuts only lead to regulatory and reputational risk.

    Many newer regulations prioritize green chemistry and reduced hazardous waste. We’ve launched projects to design cleaner manufacturing routes, reduce secondary waste, and recycle solvents wherever safe and possible. This ongoing work doesn’t always deliver cost savings immediately, but it grounds us with resilience and market credibility. Feedback from industry partners confirms that an investment in sustainability is now often a qualification barrier, not just a ‘nice-to-have.’

    Conclusions Drawn from the Factory Floor

    Supplying 3,4-Dinitroaniline isn’t a matter of sending out drums and invoices. It’s a process anchored in chemical know-how, a drive for quality beyond minimum checklists, and honest engagement with the practical needs of industrial users. Our approach brings the focus of actual manufacture and the lessons learned from daily production challenges. With us, quality control holds sharp, process transparency runs deep, and the connection with users remains grounded in shared success rather than short-term transaction. The journey of 3,4-Dinitroaniline, through nitration, purification, testing, and delivery, tells a story — and our facility writes it one batch at a time.