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HS Code |
368954 |
| Cas Number | 2216-35-5 |
| Molecular Formula | C9H11Cl |
| Molecular Weight | 154.64 |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 228-230 °C |
| Melting Point | -22 °C |
| Density | 1.049 g/cm3 |
| Refractive Index | 1.535 |
| Flash Point | 94 °C |
| Solubility In Water | Insoluble |
| Purity | Typically ≥98% |
| Synonyms | α-Chloro-3,4-dimethyltoluene |
| Smiles | CC1=CC(C)=CC(CCl)=C1 |
| Ec Number | 218-672-2 |
| Un Number | UN 2689 |
As an accredited 3,4-Dimethylbenzyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 3,4-Dimethylbenzyl Chloride is packaged in a 250 mL amber glass bottle, sealed with a screw cap and safety labeling. |
| Shipping | 3,4-Dimethylbenzyl Chloride is shipped in tightly sealed containers, away from heat, sparks, and open flames. It is classified as a hazardous material due to its flammability and corrosiveness. Shipping must comply with local and international regulations, including proper labeling, documentation, and using appropriate secondary containment to prevent leaks or spills. |
| Storage | 3,4-Dimethylbenzyl Chloride should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat, sparks, and open flames. Keep away from incompatible substances such as strong oxidizers, bases, and acids. Avoid exposure to moisture. Store in a designated chemical storage area and ensure proper labeling. Use secondary containment to prevent leaks or spills. |
Applications of 3,4-Dimethylbenzyl Chloride in Industrial Manufacturing3,4-Dimethylbenzyl Chloride serves as a key intermediate in downstream chemical processes requiring selective benzylation, particularly for specialty chemicals, agrochemicals, pharmaceuticals, and polymer additives. Our production is vertically integrated and optimized for consistent purity, traceability, and precise specification control. 1. Synthesis of Specialty Agrochemical IntermediatesAgrochemical manufacturers incorporate 3,4-Dimethylbenzyl Chloride to build complex active ingredients for herbicide and pesticide formulations. Its selectivity and reactivity support targeted alkylation steps, ensuring high-yield conversions with minimal by-product formation. The intermediate typically undergoes nucleophilic substitution or further functionalization in the presence of controlled catalysts and stoichiometry, resulting in enhanced process efficiency and reproducibility. Product use requires strict compliance with agrochemical regulatory dossiers for global market access. Industry compliance standards
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2. Pharmaceutical Intermediate ManufacturingPharmaceutical companies use 3,4-Dimethylbenzyl Chloride as a protected benzylation agent during multi-step synthesis of drug substances. This raw material supports the introduction of a stable side chain while maintaining critical enantiopurity through controlled conditions. Our production plant offers batch traceability and low residual impurity levels, which meet ICH Q7 GMP requirements. The material enters routes for antihypertensive, antipsychotic, and selective CNS drug development, where side chain integrity directly impacts pharmacological activity and regulatory acceptance. Industry compliance standards
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3. Advanced Polymer Modifier SynthesisDownstream polymer manufacturers apply 3,4-Dimethylbenzyl Chloride in the preparation of high-performance polymer modifiers and cross-linking agents. It acts as a functionalizing compound to introduce specific alkyl groups onto polyolefins or specialty resins, optimizing mechanical strength and chemical resistance. During the customization of engineering plastics, the chemical enters either as a pre-polymer block or as a grafting monomer, dependent on targeted end-use requirements. Consistent batch purity supports repeatable product performance and compliance with key industrial standards. Industry compliance standards
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4. Synthesis of Fragrance and Aroma CompoundsThe fine chemical and fragrance sector uses 3,4-Dimethylbenzyl Chloride to synthesize aromatic compounds by controlled alkylation. The material supports selective side chain modifications in essential oil derivatives and musk analog production, where high-purity intermediates safeguard sensory quality and regulatory compliance. The compound’s reactivity profile ensures precise conversion to target aldehydes or alcohols, minimizing trace impurities that impact olfactory character. Process reliability and impurity control play critical roles for manufacturers serving regulated consumer markets. Industry compliance standards
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5. Advanced Dye Intermediate ProductionDye and pigment manufacturers use 3,4-Dimethylbenzyl Chloride as an alkylating agent for producing advanced dye intermediates. Its controlled reactivity enables synthesis of benzylated chromophores and functional dye precursors used in textile, leather, and ink industries. Integrated into multistep routes, this intermediate supports high color yield while controlling side reactions. Production stability and impurity minimization ensure compliance with consumer safety and environmental directives for dyed goods and printing inks. Industry compliance standards
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Competitive 3,4-Dimethylbenzyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
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3,4-Dimethylbenzyl Chloride stands out in the family of benzyl halides. Over the years, this compound has drawn attention in both specialty chemistry and large-scale industrial synthesis. Direct contact with the raw reactions and everyday plant operations teaches us much about its behavior and quirks. Through our hands-on preparation and longstanding manufacturing practice, we know the true character of this material, not just its appearance on paper.
We produce 3,4-Dimethylbenzyl Chloride (C9H11Cl), a compound with methyl groups attached to the third and fourth positions on the benzene ring. Its clear, colorless to pale yellow liquid form makes it easy to recognize during quality checks. Those who have handled different benzyl chlorides can feel the difference in its density and observe subtle distinctions in its boiling point and flow during transfer. The arrangement of two methyl groups on the ring influences not only the physical properties but also the reactivity, showing up during chlorination steps and downstream reactions in the plant.
Seasoned plant workers spot its signature aroma and slightly higher viscosity—a direct result of the extra methyl groups compared to monochlorinated benzyl derivatives. During distillation, careful heating prevents decomposition, and keeping oxygen away preserves the final quality. Time spent running reactors and monitoring product streams tells us that 3,4-Dimethylbenzyl Chloride requires vigilance during temperature transitions and transitions of tank volumes. This compound isn't known for caking or clogging, but meticulous cleaning after each batch prevents cross-contamination, especially if the next job uses a more sensitive feedstock.
Cleanliness matters most for pharmaceutical intermediates and agricultural specialties. We maintain GC purities usually above 99%, which chemists always appreciate in bench and pilot scale trials. In the factory, it arrives at customers’ sites either in steel drums lined against corrosion or in polyethylene containers, depending on the volume and delivery route. We’ve had our share of delivery audits, always fielding questions about trace impurities and ensuring that every sample bottle matches what came off the main reactor. Consistent color, clarity, and odor give peace of mind to QA inspectors who have smelled dozens of products over a career.
Most requests for 3,4-Dimethylbenzyl Chloride originate from fine chemical synthesis work. Over the last decade, customers in the pharmaceutical and agrochemical sectors have used it as a core building block. Its structure allows for regioselective reactions, giving rise to products requiring minimal purification at later stages. We supply this product to companies that keep confidentiality about their end use, but our experience shows it regularly appears in the alkylation step for new active ingredients and as an intermediate for performance additives.
This compound performs differently than unsubstituted benzyl chloride. Those methyl groups confer both hydrophobicity and steric hindrance, impacting how downstream functional groups attach and dictate selectivity. In practical manufacturing terms, this results in fewer byproducts and smoother separations. This is a case where formulation chemists, not just engineers, appreciate how a subtle tweak in substitution can save weeks of process development.
As with all benzyl chlorides, careful handling remains essential. Plant teams follow strict ventilation policies and wear suitable personal protection. We have never treated it as a “routine” job—even minor exposure to the vapor requires prompt decontamination. Routine training and clear protocols keep our team safe, and decades without a lost-time incident on this line show that the protocols work. Drumming up close, you notice the heavier feel compared to unsubstituted analogues, and experienced crew members always double-check drum seals, especially during summer shipments when expansion risk grows.
In spill drills, we prefer granular absorbents. The product can sting if it contacts skin, and we’ve invested in upgraded eyewash and shower stations. Our emergency response guidelines stem from actual incident experience, not theory. Repeated drills reinforce how fast you must act to limit worker risk, especially with larger storage tanks onsite.
After years of manufacturing various substituted benzyl chlorides, we appreciate how much subtle shifts in molecular structure impact reactivity. 3,4-Dimethylbenzyl Chloride resists oxidation more effectively than some mono-methyl variants, something that matters during storage and shipment. Its rate of hydrolysis in alkaline conditions is slower, which simplifies certain workups. We see smaller off-gas volumes and less color development on long-term shelf stability studies compared to 2-methylbenzyl chloride.
During actual synthesis, reactions involving this compound typically generate fewer side products compared to those using the unsubstituted parent. This translates to higher resource efficiency—a real benefit not just on paper but evident on the plant floor when operators dispose of less waste. Customers accustomed to the hassle of fractionating and recycling solvents with other benzyl chlorides often note smoother operations and better yields with this material.
In production, each lot faces triple inspection before filling. Lightweight containers can deform after long days in the warehouse, so we avoid thin-walled plastics even if they lower shipping costs. Our logistics team prefers metal drums lined with an inner poly layer, based on decades of observing leakage risks and the headache of spillage cleanup. Frequent feedback from end users helped us tweak drum closure systems, adding an extra moisture seal and choosing anti-corrosion coatings that last longer in humid shipping conditions.
We tag every container with a batch identifier and digital summary of lab test results, not just a date and generic product name. This saves headaches in the field, especially for customers who need traceable chain-of-custody for regulated end uses. Simple touches, rooted in long experience—such as unambiguous labeling and reinforced drum lids—mean delivery time focuses on safe product use, not damage control.
After years in the business, we have learned what conditions work best for extended storage. Keeping containers sealed and stored in cool, shaded areas stays effective. Exposure to sunlight or hot, humid air tends to speed up trace color changes, so most shipments move out early each week to limit time sitting in transit. On rare occasions when a drum sits too long at a freight terminal, we inspect color and odor before releasing the inventory. Our storage team relies on continuous temperature and humidity monitoring. Built into our SOP is a policy to reject any drums showing pressure buildup, which has occurred when less-experienced suppliers used subpar containers. Regular stock rotation and container checks help ensure we ship only material with lab-verified specs matching our own release criteria. It’s tempting in procurement to prioritize price, but storage headaches always eat up any savings. Only from years of shipping, storing, and re-certifying old inventory do you learn that reliable packaging prevents 99% of downstream complaints. Stability starts in the factory and continues through every link in the supply chain.
Lab chemists rely on 3,4-Dimethylbenzyl Chloride for critical steps in synthesizing tailored molecules. Academic teams have published methods using this material to alkylate heterocycles and form custom arylamino derivatives. Our own feedback from customers shows that using this particular substitution pattern enhances selectivity, resulting in higher-purity isolates and less need for corrective distillation or extraction. In practice, end users tell us 3,4-Dimethylbenzyl Chloride offers advantages in nucleophilic substitution—yielding target compounds that would otherwise require harsher reagents or longer processing times. Some agricultural chemistry labs have used it to prepare specialty herbicides and seed treatments featuring improved persistence and compatibility. Product developers appreciate how it modifies the durability and function of advanced polymer additives, acting as an efficient anchor for downstream reactions. A handful of battery and electronics research groups purchase small lots to investigate new precursor routes. The compound’s distinct reactivity profile allows them to explore modifications in polymer chains or surface treatments, benefiting from branch selectivity and manageable leaving-group behavior. Recently, the surge in demand for custom fine chemicals has brought more requests from innovators aiming to push the boundaries of catalysis and surface functionalization. The real-world experience gained by supporting these varied sectors reinforces the compound’s versatile role.
Region by region, compliance standards differ. Our experience covering shipments for EU and North American clients means adhering to REACH and TSCA regulations routinely. Pre-shipment inspections and random sample pulls keep us on track. Meeting both customer documentation requirements and local safety data mandates matters to regulators and buyers alike. Occasional process audits by major customers focus not just on documents but also on visible traceability in storage and recordkeeping. Many chemical plants can only speak in theory about audits, but we open our doors regularly and welcome customer representatives for facility walkthroughs. Years of shared learning with quality assurance partners has improved our documentation, keeping us ahead of changing standards.
Every seasoned chemical manufacturer faces supply chain disruptions. Price swings in key raw materials, regulatory changes, and unforeseen transportation bottlenecks impact delivery timelines. We only source starting materials from long-vetted suppliers, using real shipment history as the best guide for reliability. Build-ups in regional ports or customs holdups force us to hold safety stocks for routine batches and urgent rush orders. During global logistics slowdowns, we leverage our own warehouse space to buffer disruptions. We learned early that flexibility—dividing large production lots for phased shipments, prioritizing critical orders, and staying in close contact with customer buyers—keeps operations running. Our procurement staff tracks resin and solvent trends to forecast cost jumps that could affect downstream product pricing, and we run regular risk reviews on logistics partners. Supply chain resilience doesn’t come from theory. It comes from reacting quickly when trucks arrive late, or customs imposes unexpected checks. With transparent communication and realistic promises, we keep our customers informed and equipped to face downstream scheduling. We think in terms of long-term partnerships, not one-shipment sales.
Decades in chemical synthesis teach the importance of environmental stewardship. Managing byproducts and process ventilation is not just about compliance; it’s about responsibility to the community and workers. We invested heavily in advanced scrubbers and closed recovery loops, dramatically reducing organochlorine emissions. Production teams take pride in minimizing energy and water use by evaluating each process step for efficiency. Continuous feedback from plant staff led us to implement hourly leak checks and in-line sensors for VOCs. The cost pays off through safer working conditions and less frequent maintenance shutdowns. We work closely with local environmental agencies, hosting tours and sharing data to build trust. Lessons learned from pilot efforts inform how we handle waste, segregate recyclable materials, and optimize cleanup operations. Years ago, wastewater disposal imposed limits on batch frequency. Through process redesign and recycling protocols, we now reuse key solvents in back-to-back runs, slashing both costs and environmental impact. Staff members stay trained and aware of new regulations because change happens quickly in the chemical sector. Feedback from the community and local government, not just from regulators, shapes our environmental strategy. Our reputation grows not by accident but by ongoing dialogue and transparent action in environmental management.
On the plant floor, continuous improvement means everything. We meet each week to assess yields, batch times, and solvent recoveries for the 3,4-Dimethylbenzyl Chloride line. If any operator spots contamination or a slow reaction, managers and engineers review the details immediately, amending procedures as needed. The real value lies in open feedback loops—from the person filling the drums to the teams handling waste. A few years back, we shifted to more precise temperature controls during chlorination, achieving tighter product distributions and fewer off-spec batches. This change came from repeated observations, not just lab data. Similar incremental upgrades include enhanced agitation in reactors, faster drum filling based on ergonomic studies, and routine sampling from different reactor zones to catch heterogenous feeds. Input from customers drives many upgrades. A leading agrochemical client suggested we adjust solvent profiles to reduce cleaning time in their plants. After a pilot run and collaboration, we rolled out a change, saving hours for both parties. In real chemical manufacturing, shared feedback benefits everyone in the chain. Small details make enormous difference—shorter transfer lines to prevent cold spots, insurance spares for pumps, and colorimetric checks at every loading dock. These don’t come from manuals, but from teams committed to learning and improving, every shift.
The chemical landscape keeps evolving, both in technology and market needs. Increasing interest in tailored, high-purity intermediates demands agility from manufacturers. As customers look to greener chemistry and more sustainable supply chains, we continue searching for improvements in both process yield and environmental profile. Our development team tracks emerging research on alternate activation methods for benzyl chlorides, aiming to further reduce side products and waste. Pilot projects already explore new catalyst systems and energy-efficient reactors. The lessons learned from current large-batch syntheses inform every small-scale trial, ensuring new approaches are scalable, safe, and robust. We keep channels of communication open with academic and industrial partners, sharing what we learn from unexpected lab results or unique customer feedback. This open ethos supports progress across the sector and prepares us to meet the next generation of product requirements, whether in pharmaceuticals, agrochemicals, or new material science breakthroughs. After years in the business, it’s clear: manufacturing 3,4-Dimethylbenzyl Chloride is about more than producing a molecule. It’s about safety, precision, teamwork, and a constant drive to do better for the industry and the community. Every drum shipped carries a history of practical know-how and a commitment to continuous improvement.