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3,4-Dichloro-OMega-Nitrostyrene

    • Product Name 3,4-Dichloro-OMega-Nitrostyrene
    • Alias 2,3-Dichloro-β-nitrostyrene
    • Einecs 702-913-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    613983

    Chemical Name 3,4-Dichloro-omega-nitrostyrene
    Molecular Formula C8H5Cl2NO2
    Molecular Weight 218.04 g/mol
    Appearance Yellow to orange crystalline solid
    Melting Point 82-85°C
    Solubility Slightly soluble in water; soluble in organic solvents
    Cas Number 23491-96-7
    Purity Typically ≥98%
    Storage Conditions Store at 2-8°C, protected from light and moisture

    As an accredited 3,4-Dichloro-OMega-Nitrostyrene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 25g amber glass bottle, tightly sealed, labeled "3,4-Dichloro-Ω-Nitrostyrene", with hazard symbols and batch information clearly printed.
    Shipping 3,4-Dichloro-OMega-Nitrostyrene is shipped in accordance with applicable chemical safety regulations. It is securely contained in sealed, labeled containers to prevent leaks and contamination. Packages include safety data sheets (SDS) and hazard labeling, and are transported by certified carriers under temperature-controlled, dry conditions to ensure product stability and regulatory compliance.
    Storage 3,4-Dichloro-ω-nitrostyrene should be stored in a tightly sealed container, away from light, heat, and moisture, in a cool, well-ventilated, and dry area. Ensure the storage area is segregated from incompatible substances such as strong oxidizers and acids. Properly label the container, and handle it using appropriate personal protective equipment to avoid inhalation, ingestion, or skin contact.
    Application of 3,4-Dichloro-OMega-Nitrostyrene

    Applications of 3,4-Dichloro-OMega-Nitrostyrene in Industrial Manufacturing

    As a direct manufacturer of 3,4-Dichloro-OMega-Nitrostyrene, we supply this intermediate to specialized sectors requiring advanced molecular functionalities. Its established performance in downstream chemical synthesis enables high-value transformations in the development of specialty molecules, driven by specific process requirements and stringent regulatory compliance. The following sections outline the principal real-world industrial scenarios where our material integrates into downstream production lines to achieve consistent quality and yield.

    1. Advanced Pharmaceutical Intermediate Synthesis

    This compound is widely employed as a key intermediate in the multi-step synthesis of new-generation active pharmaceutical ingredients (APIs), particularly within the field of synthetic organic medicinal chemistry. Downstream manufacturers utilize its electron-deficient aromatic ring and nitro substituent for Michael addition and cross-coupling reactions, crucial in assembling pharmacologically active heterocyclic systems. Incorporation into multi-ton scale pharmaceutical routes involves direct input into protected stage assemblies, where both regulatory traceability and reproducibility are critical.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia Monographs (Ph. Eur. general chapter 2034)
    • US FDA cGMP (21 CFR Part 210/211)
    • China Pharmacopoeia (ChP) Batch Record Traceability

    Typical usage ratio

    • 0.7-1.5 molar equivalents vs. linking reagent; actual requirement depends on stepwise conversion efficiency and impurity profiling stages

    Downstream process integration

    • Dosed into core condensation or coupling stages after initial fragment assembly; participates in sequential ring-forming or installation stages under inert atmosphere and often in polar aprotic solvents

    Final product types

    • API intermediates for anti-inflammatory, oncology, or anti-infective drugs
    • Heterocyclic scaffolds for pharmaceutical research
    • Precursor blocks for patent-protected small molecules
    • Scale-up samples for clinical development batches

    2. Agrochemical Synthesis Building Block

    Manufacturers of crop protection actives source this material as a valuable halogenated nitro-aromatic precursor in the synthesis of selective herbicides, fungicides, and insecticidal agents. Its reactivity profile supports downstream functionalization, especially in forming substituted anilines or benzenesulfonamides, where robust chlorinated intermediates are needed for structure-activity modified lead compounds.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for Agrochemical Manufacturing
    • China National Standard GB/T 1600-2021 for Pesticide Intermediates
    • EU REACH Regulation (EC 1907/2006) for downstream safety
    • CropLife International Technical Guidelines

    Typical usage ratio

    • 1.0-1.4 molar equivalents depending on the target molecule substitution pattern; adjusted in-process as per final conversion and regulatory-mandated impurity limits

    Downstream process integration

    • Dosed at key amination, nitro-reduction, or ring-functionalization steps under strictly monitored reaction conditions to yield specific crop protection active intermediates

    Final product types

    • Pyridine-based herbicides
    • Chlorinated fungicide actives
    • Precursor for phenoxyacetic acid derivatives
    • Finished technical-grade agrochemical actives for formulation

    3. Specialty Dye and Pigment Manufacturing

    Within advanced colorant production, this compound functions in the synthesis of functionalized azo and anthraquinone dye intermediates. Manufacturers exploit its nitro and dichloro substitution for targeted cross-coupling and reduction steps, leading to robust, lightfast coloring agents for industrial and textile-scale applications where spectral stability is critical.

    Industry compliance standards

    • Oeko-Tex Standard 100 (Textile Eco-Toxicological Compliance)
    • ISO 9001 Quality Management in Dyes Manufacturing
    • REACH Annex XVII Restrictions on Aromatic Amine Precursors
    • ZDHC Manufacturing Restricted Substances List (MRSL)

    Typical usage ratio

    • 0.5-1.2 molar equivalents per chromophore synthesis step; adjusted for yield and color intensity across batch scales

    Downstream process integration

    • Introduced during coupling or pre-reduction phase to build intermediate aryl structures, followed by further cyclization or diazotization for colorant finalization

    Final product types

    • Reactive and disperse dyes for polyester/cotton blending
    • High-performance pigments for plastics and inks
    • Special effect colorants for automotive coatings
    • Intermediates for electronic display pigments

    4. Electronic Chemicals: Precursor for Functional Monomers

    Producers of specialized resins and electronic packaging materials utilize this compound to introduce electron-withdrawing substituents into synthetic monomers or oligomers, crucial for developing high-temperature-resistant materials and photoresist components in microelectronics. Its defined reactivity contributes specifically to the fine-tuning of monomer charge transport and dielectric properties.

    Industry compliance standards

    • IPC-4101B (Base Materials for Printed Boards)
    • IEC 61249-2-7:2017 (Materials for Printed Circuits)
    • ISO 14001:2015 (Environmental Management in Electronic Chemicals)
    • RoHS (EU Directive 2011/65/EU) for downstream electronics safety

    Typical usage ratio

    • 0.3-0.9 molar equivalents based on targeted functional group density and resin formulation requirements

    Downstream process integration

    • Charged into monomer functionalization or polymer back-bone modification steps; reacts under controlled temperature and atmosphere before polymerization or further chemical shaping

    Final product types

    • High-performance epoxy resins for PCB fabrication
    • Functionalized monomers for photolithography resists
    • Dielectric materials for microchip encapsulation
    • Specialty polymer blends with halogen resistance

    5. Fine Chemical Synthesis for Research Reagents

    This compound also finds critical use with leading fine chemical companies supplying reagent catalogs, where it forms the backbone for synthesizing reference materials and screening tools. Control over purity, by-product profile, and traceable lot documentation are priorities for these applications, as batches often go directly to R&D or quality control use.

    Industry compliance standards

    • ISO 17034:2016 (Reference Material Producers Accreditation)
    • GLP (OECD Principles of Good Laboratory Practice)
    • REACH Article 5 (Duty to Register)
    • Internal QC protocols for traceability

    Typical usage ratio

    • Varies from 0.2-1.0 molar equivalents, optimized per batch according to required analytical purity or specific target structure outlined in the research synthesis plan

    Downstream process integration

    • Added during initial reagent formation, followed by purification steps tailored to meet catalog-grade or reference-standard quality

    Final product types

    • High-purity research reagents for academic and industrial laboratories
    • Analytical reference materials
    • Screening intermediates for high-throughput discovery
    • Calibration standards for chromatographic systems
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    Certification & Compliance
    More Introduction

    Introducing 3,4-Dichloro-OMega-Nitrostyrene: Insights From the Factory Floor

    What 3,4-Dichloro-OMega-Nitrostyrene Brings to the Table

    Inside any modern chemical plant, specialty intermediates create the backbone of countless applications, but few draw as much attention as 3,4-Dichloro-OMega-Nitrostyrene. We have produced this compound for years, refining its synthesis, monitoring batch integrity, and listening closely to feedback from synthesis chemists, technical buyers, and process managers. Our team spends long hours perfecting each lot because we know the downstream impact touches everything from fine chemicals to rapidly advancing pharmaceutical pipelines.

    Our usual production model carries the designation 3,4-DCONS-PL/AT, a reference to the proprietary route and purification steps we have honed using feedback and rigorous in-process controls. In our facility, this product leaves the reactor with tightly controlled assay levels and minimal byproduct. We focus a great deal on minimizing trace contaminants and optimizing crystallization so that it handles well during transfer and weighing. This product’s appearance—a pale yellow crystalline solid—is much more than a visual cue; we correlate color and form with purity and stability by cross-checking each lot during packaging.

    Real-World Use: The Chemist’s Perspective

    On the shop floor, we watch how the product flows, integrates with solvents, and behaves under various storage conditions. Labs working on new heterocyclic scaffolds, nitroarene coupling, or unique styrene derivatives rely on a consistent melt-point and defined particle size for repeatable results. At our plant, attention to these fine details has meant customers avoid time-consuming purification cycles on arrival. Even after shipping overseas, our lots retain tight physicochemical properties, which keeps research projects on schedule.

    Rarely do spec sheets tell the full story. Syndicated laboratories and pharmaceutical innovators share stories with us after running scale-ups: batches from other vendors produced troublesome off-target condensations or left unexpected residues in their glassware. We keep our own inventory chain clean by continuously screening for these problematic co-products, which we identified after running several failed syntheses during our process development phase.

    Why 3,4-Dichloro-OMega-Nitrostyrene is Sought After

    Market activity for this compound speaks volumes about the demand for high-grade nitrostyrene derivatives. In dye manufacturing and advanced polymer research, subtle changes to backbone substituents unlock entirely new families of materials. We have seen process engineers experiment with our product in high-throughput screens, trying to push yields in aromatic coupling or achieve improved selectivity in hydrogenation steps. The dual chloro groups and the para-nitro substituent break the general electron pattern seen in most styrene derivatives, giving unique reactivity in both base- and acid-catalyzed reactions.

    Production managers in our own facility pay attention to these electronic effects. In regular group meetings, we troubleshoot isolation protocols to avoid loss of the nitro group during drying, as others sometimes see. That preservation of functional groups enables downstream partners to skip requalification, saving both reagents and labor.

    How This Product Differs From Standard Nitrostyrenes

    Many facilities process basic nitrostyrene or single-chloro analogues, but their products don’t deliver consistent reaction profiles in selective transformations. We’ve seen, through hands-on experience, that leaving out a single halogen alters melting range and reactivity. Clients switching from unsubstituted or mono-chloro nitrostyrenes have reported slippage in reaction control or unwanted isomer formation. Our double-chloro, para-nitro product maintains sharper transitions under heat and pressure, which is particularly important during column loading or in pressure vessels.

    Over time, technical teams from both agrochemical and pharmaceutical spheres have highlighted how multi-chloro patterns provide an edge in designing new ligands, energetic materials, or challenge compounds for screening. A batch with only one chloro group often misses the intended target in palladium-catalyzed reactions. In feedback calls, our partners say the dual chloro pattern saves days or weeks in development, reducing the need for post-purification and increasing the overall yield of target molecules.

    Packing, storage, and shelf life remain central topics in our development meetings. Without proper stabilization, basic nitrostyrenes degrade more quickly, leading to visible discoloration and shifting assay. We employ packaging protocols built on years of observing small failures—desiccant packs, light-resistant bags, and rapid cool-down after lot preparation. These practical improvements come directly from troubleshooting sessions with clients who operate under GMP or tight specs.

    Production Reliability: Building Trust Through Consistency

    Manufacturing specialty nitrostyrene derivatives takes more than just following a published procedure. Early in our work, batch disparities prompted us to overhaul both the glass-lined reactor cleaning process and the temperature ramp algorithms in product isolation units. By installing inline analytics instead of relying on endpoint QC alone, we now identify and resolve side-reactions in real time.

    One characteristic we focus on is the stability of the nitrostyrene double bond. Manual handling, exposure to atmospheric moisture, and even transport stresses can trigger polymerization or lead to microscale decomposition. Factory teams have iterated container selection repeatedly, finally settling on inert-liner drums and sealed barrier pouches that ship worldwide with consistent results. Customer feedback drove this improvement; receiving sticky or partially decomposed nitrostyrene in poorly sealed packages caused project delays, and customer trust erodes quickly in these scenarios.

    Quality Controls: What Matters in the Laboratory Actually Starts in Production

    We emphasize pre-shipment testing, but the real step change came from instituting ongoing stability trials. Each year, we simulate six-month and one-year storage, including cycles between room temp and intended cold storage. We learned that a single sub-batch, if exposed to less-than-ideal humidity, impacts analytical reproducibility downstream. Our QC lab correlates minor IR or NMR changes with final application success, so no sub-batch leaves the door without tracking data tied back to both normal and stress conditions.

    A large part of our philosophy comes from supporting users who communicate directly. A bench scientist in an industrial research lab or a pilot-plant chemist in need of material for a multistep synthesis both depend on starting materials that align exactly with the data prints we supply. We have witnessed firsthand the impact of receiving out-of-spec precursors—the entire process stalls, costing time and increasing frustration. We treat the incoming requests for additional characterization as opportunities, not annoyances, and use them to sharpen our own monitoring. This approach means the product is more than a number on a certificate—it is a reliable building block for whatever comes next.

    Meeting Real-World Application Demands

    End users—especially in specialty chemical synthesis—often experiment at the edge of what is possible with known substrates. A lead researcher in organometallic chemistry once described how switching to our 3,4-Dichloro-OMega-Nitrostyrene increased their hit rate during catalyst screening, not because of the apparent purity but because trace metals, polymeric fragments, and labile byproducts simply didn’t show up. Those details can’t be faked or glossed over in a spec sheet; they are the difference between a week spent debugging a stalled reaction and a week spent advancing discovery.

    On occasion, we find ourselves coaching first-time users through solvent selections, heating rates, and post-reaction cleanup. From our own pilot-scale optimization, we know that this material tolerates a wide range of solvents, including aromatic hydrocarbons and moderately polar aprotic solvents. Processing speed increases when operators have confidence that the lot in their hands will not seed unplanned side reactions. With every dispatch, we include technical guidance based on our in-house test campaigns, because new application spaces open up day by day.

    Understanding Market Trends in Specialty Nitroaromatics

    Industry shifts toward sustainable routes and more complex target molecules mean demand for specialty substituted nitroaromatics is rising. In the last few years, we have seen orders from fields as varied as high-voltage insulation, specialty inks, and diagnostic kit assembly. These require materials that do not just check off a molecular formula, but pass muster on trace analyte level, long-term supply visibility, and ongoing support during process troubleshooting.

    We keep an eye on regulatory trends too, particularly those touching handling, transport, and registration of precursors with toxicological flags. Our track record with 3,4-Dichloro-OMega-Nitrostyrene has prompted us to create full chain-of-custody documentation and robust batch tracing, both to aid responsible use and to help downstream partners face their own compliance scrutiny. We allocate batch-recall resources should any anomaly arise, making sure our quality systems are not just paperwork exercises but real, actionable contingency plans. Any flagged batch is quarantined and goes through root-cause analysis before returning to circulation.

    Continuous Improvement and Customer Collaboration

    Day in, day out, our process chemists and product managers meet with counterparts across continents to field application challenges and improvement requests. By logging both near-misses and successful lot qualifications, our team learns which parameters make tangible differences: not only analytical purity, but also dustiness, moisture stability, and ease of weighing. These so-called minor details only seem small until bench work reveals gaps. Our continuous improvement cycles draw not from KPIs alone but from authentic, sometimes painful, stories of failed syntheses, wasted manpower, or scale-up headaches.

    On several occasions, customers have shared analytical profiles from commercial-scale runs, flagging microwave artifacts, trace contamination, or varying crystal morphologies. We return the favor by testing back and suggesting tweaks in storage or handling, all so that their teams can avoid known pitfalls. This two-way street builds community and opens up new opportunities for shared learning. We make no secret of how much our best suggestions come not from internal brainstorming but from nervous emails and after-hours troubleshooting calls.

    Beyond Specification Sheets: Real-World Performance Difference

    A single year’s experience handling thousands of kilograms gives the production team a sense of which tweaks actually show up in application data. We have adapted drying temperatures, blend runs, and filtration steps simply because end-users found outlier properties in downstream analytics. Our technical team reviews customer application notes side by side with plant logs, tracking how long a given batch sits on warehouse shelves and how it responds to cycling climates, both humid and arid. It is one thing to turn out a material that looks fine on the day it ships, but entirely another to achieve this level of field-tested reliability months later.

    In polystyrene derivative synthesis, low levels of residual sodium or potassium can skew catalyst selectivity or even poison benchmark reactions. Recognizing this, our process engineering group identified and eliminated key contamination sources, even running periodic clean breakouts of shared equipment to avoid legacy impurities. Downstream, specialty application users trace improved selectivity and higher reproducibility directly to these interventions.

    The Human Element: Chemical Manufacturing as Craft

    People sometimes overlook how much craft still plays a role in today’s specialty chemical manufacturing. Our plant team applies judgment every time a batch moves from crude product to dried, formulated lot. Some staffers bring decades of experience—having seen fads in process intensification or green chemistry come and go, they know which shortcuts save effort and which risk costly mistakes downstream. We encourage teams to speak up about anomalies before those issues trace forward into customer lots, believing transparency earns more business than excessive claims.

    After a decade refining both process and feedback integration, our approach views specialty materials not as undifferentiated commodities, but as components woven into scientific and industrial progress worldwide. This lesson remains especially true with challenging molecules like 3,4-Dichloro-OMega-Nitrostyrene, where batch-to-batch predictability can make or break the next innovation in fields as varied as electronics, materials science, or advanced analytical chemistry.

    Looking Ahead: Innovation Rooted in Practical Experience

    Next steps in specialty intermediate manufacturing will go beyond incremental improvements. Our participation in multi-site research consortia, combined with continuous investment in analytical tech and operator training, means new derivatives and improved scale-up routes are always in progress. As performance targets and application domains evolve, we pay careful attention to how core products like 3,4-Dichloro-OMega-Nitrostyrene can be adapted through co-crystallization, alternative counterions, or surface treatments that prolong shelf and application life.

    We remain rooted in the tactile, day-by-day practice of making precise chemicals for a demanding world. Every kilogram of 3,4-Dichloro-OMega-Nitrostyrene that leaves our warehouse reflects years of learning, troubleshooting, and human effort—a fact not captured in routine datasheets. Our ongoing communication with users, coupled with hands-on process improvement, ensures that each new lot rises to meet the real, on-the-ground standards of today’s agile industries.