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HS Code |
244025 |
| Chemicalname | 3,4-Dibromobenzaldehyde |
| Casnumber | 34841-35-5 |
| Molecularformula | C7H4Br2O |
| Molecularweight | 279.92 g/mol |
| Appearance | White to off-white solid |
| Meltingpoint | 111-115 °C |
| Purity | Typically ≥98% |
| Solubility | Slightly soluble in water; soluble in organic solvents like ethanol and dichloromethane |
| Density | 2.16 g/cm³ |
| Smiles | C1=CC(=C(C=C1Br)Br)C=O |
| Inchi | InChI=1S/C7H4Br2O/c8-6-2-1-5(4-10)7(9)3-6/h1-4H |
As an accredited 3,4-Dibromobenzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 25-gram amber glass bottle with a screw cap, labeled “3,4-Dibromobenzaldehyde,” featuring safety and handling instructions. |
| Shipping | 3,4-Dibromobenzaldehyde is shipped in tightly sealed containers, protected from light and moisture. It should be stored at room temperature and handled with appropriate safety precautions. Packages must be clearly labeled, comply with local shipping regulations for hazardous chemicals, and may require documentation such as safety data sheets and hazard declarations. |
| Storage | 3,4-Dibromobenzaldehyde should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from incompatible substances such as oxidizing agents. It should be kept away from sources of ignition and direct sunlight. Proper chemical storage cabinets, especially those for organics or hazardous substances, are recommended. Always follow local regulations and safety data sheet (SDS) instructions. |
Applications of 3,4-Dibromobenzaldehyde in Industrial Manufacturing3,4-Dibromobenzaldehyde serves as a core intermediate in modern industrial organic synthesis. With high halogen selectivity and aldehyde reactivity, this material supports specialized transformation steps in several regulated sectors. The following scenarios detail its use in downstream value chains managed by manufacturers that prioritize production reliability and precise formulation standards. 1. Agrochemical Synthesis: Key Intermediate in Fungicide ManufacturingManufacturers utilize this compound as a building block in the synthesis of advanced active ingredients, particularly for strobilurin-type fungicides. Its controlled introduction in multi-step reactions provides the halogenated aromatic core necessary for downstream cyclization and condensation steps, supporting the effective targeting of fungal pathogens in regulated agricultural markets. Industry compliance standards
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2. Pharmaceutical Intermediate: Custom Synthesis for API Building BlocksWithin the pharmaceutical industry, this compound acts as a crucial intermediate for specialty contract manufacturing organizations (CMOs) focused on producing advanced aromatic and heterocyclic systems. Formulators leverage its reactivity for introducing dibromo-selective motifs into complex APIs, adhering to strict traceability and impurity controls during multi-stage synthesis workflows. Industry compliance standards
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3. Specialty Dye and Pigment Synthesis: Aromatic Core for Advanced ColorantsChemical dye manufacturers employ this raw material as a precursor for constructing novel brominated chromophores. Its dual bromine substitution accelerates downstream azo coupling and condensation reactions, which is essential for producing color-stable, high-purity pigments used in industrial inks and plastic coloration, meeting region-specific migration and toxicity guidelines. Industry compliance standards
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4. Liquid Crystal Intermediate: Component in Display Material ProductionProducers of liquid crystal (LC) materials integrate this aromatic aldehyde as an intermediate step in preparing mesogenic compounds with strict purity and alignment performance requirements. The consistent introduction of bromine atoms aids the fine-tuning of dielectric and optical properties required for modern LC displays, in compliance with highly monitored electronic sector protocols. Industry compliance standards
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Years of running reactors, watching the color shift as the process handles each stage of bromination, and running quality checks on the output—they teach a lot about what actually matters in a bottle of 3,4-Dibromobenzaldehyde. This compound, with the formula C7H4Br2O, shows up in labs and production sites wherever fine chemical synthesis needs a well-defined, reliable building block. From my own seat at the plant, I can say the demand for tight control over every batch hasn’t wavered. Our process aims for consistent crystalline product with high purity, typically over 98% by GC, and a melting point that falls reliably in the expected range.
Handling raw materials and stepping through a multi-stage synthesis process, we’ve seen how subtle shifts in input quality or temperature profiles can make or break an entire lot. 3,4-Dibromobenzaldehyde carries a pale-yellow to off-white appearance, packaged in moisture-tight drums to prevent degradation before it reaches a customer’s hands. Every kilogram that leaves our site undergoes solid state NMR checks and purity confirmation. It’s not hype—it’s experience that sets a manufacturer approach apart from traders. Plant operators work out the bugs so chemists downstream don’t have to.
Well before a bottle lands on a lab bench, we’ve set expectations. The dibromo-substitution at the 3 and 4 positions fundamentally changes the reactivity profile compared with mono-brominated or plain benzaldehyde. In halogenation, the pattern of substitution directs where new functional groups can attach, which gives this aldehyde an advantage for elegance and control in forming specialized ligands, fine organic intermediates, or active pharmaceutical ingredients.
Other manufacturers sometimes blur the distinction between meta- and para-substitution, but the 3,4-connection gives a direct path to target molecules that call for steric hindrance and precise reactivity. Reliability in this position-specific chemistry matters—especially in custom synthesis shops and pharmaceutical process development where scale-up means significant financial risk. More than once we’ve run parallel batches of different isomers, tracing yield differences all the way through a synthesis, and the efficiency gains from correct substitution regularly prove out.
3,4-Dibromobenzaldehyde can serve in Suzuki couplings and other metal-catalyzed reactions that need brominated substrates as the launching point. Start with a low-grade batch—impure, loaded with mono-bromo byproducts or mixed isomer content—and the entire downstream route can stall or fail QC specs. Our in-house approach includes double-checking every step in our own lab, not just for regulatory compliance, but because we see the headaches that come from rework or unpredictable side reactions. Nobody wants to repeat a six-step synthesis because their starting material contained the wrong isomer.
Specialty chemical manufacturers and pharmaceutical teams don’t just call up hoping for any brominated aldehyde—they need consistent charset, no surprises on color, and above all, tightly controlled impurity levels. Over the years, we’ve seen this compound requested for everything from the preparation of complex heterocyclic scaffolds—where the bromine atoms act as handles for cross-coupling—to advanced dye intermediates for OLED and specialty pigment work. In these areas, reproducibility feels less like a marketing slogan and more like a basic requirement.
On the research bench, a chemist may use just a gram or two to pin down a synthetic route. At kilo-lab scale, each batch’s batch-to-batch consistency spells profit or write-off. Our teams support both: smaller quantities packed for academia and pilot projects, and multi-ton orders with full documentation for regulated market production lines. This hands-on versatility isn’t inherited from a catalog—it grew from decades of fielding customer calls about real-world synthesis problems, scale-up bottlenecks, and end-use reliability concerns.
In agrochemical work, 3,4-Dibromobenzaldehyde forms part of the routes toward selective herbicides and fungicides where placement of bromine atoms can mean the difference between biological activity and inactivity. Unintentional substitution switches or contamination with trace unreacted starting material can affect registration processes, export acceptability, and ultimately return-to-vendor situations. Our plant invests in redundancy, both in personnel training and analytical equipment, because a single mistake in a multi-ton order affects not only us but our customers’ timelines and regulatory standing.
Most of the learning happens not from textbooks but from regular conversations with chemists troubleshooting a stalled step or process managers chasing an elusive yield. The biggest difference we see between our product and generic alternatives? It’s in the number of frantic emails or late-night phone calls that come in when something’s gone wrong. Plant operators and QC chemists keep detailed batch records and share analytical data directly—because nobody wants to hear that their scale-up crashed due to a misidentified isomer or contaminant spike that QC overlooked.
Through the years, we’ve re-tooled reactor setups, swapped out filtration systems, and worked hand-in-glove with multi-national pharma partners to hit their target impurity specs—sometimes pushing our own analytical detection limits. One customer’s process repeatedly fouled due to p-bromo impurities. After troubleshooting side reactions, we added an additional purification step, eliminated the impurity, and saw their production run stabilize. Complex synthesis doesn’t just need raw material; it depends on knowing the quirks of each production lot.
A manufacturer that runs its own chemistry never waits for traders to report an issue. On-the-spot lab support, in-house method development, and a willingness to listen when a customer says, "This isn’t working"—these matter when the project budget’s on the line. Our process chemists have spent weekends running parallel experiments to match a client’s conditions, just to ensure 3,4-Dibromobenzaldehyde performs in real application. The result: once customers lock in a process with our material, they rarely look back.
Every time a truck leaves carrying a batch out to a customer, it carries the weight of lessons learned from batches that didn’t meet the mark. Early on, we battled product darkening during storage. That drove us to overhaul packaging and humidity controls in the warehouse. Customers returned old-style drums because the seals let trace moisture in, changing the melting point and sometimes forming unwanted byproducts. Now, small-change investments in drum liners and vacuum-sealed bags pay off with every successful delivery.
Two of our line managers, with over thirty years’ experience between them, take turns heading final QC sign-off. It’s a practice that started out of necessity—one too many times, a subpar drum slipped through from a rushed night shift. Now, every certified batch indicates not just “QC passed” but also the initials of the chemist who cleared it. Layers of accountability mean less finger-pointing and fewer issues downstream. Process-audit reports are open for partner review; transparency keeps both us and our customers honest.
Upgrades in spectroscopic tools and tighter process analytics began as a way to stop rejections at the receiving dock. The broader impact continues to ripple through the supply chain. Every advance in quality translates directly into more confidence at our customers’ plants. Staff training focuses not only on new equipment, but on the realities of batch-to-batch variability—how to spot a shift in product hue, what a minor scent difference can signal, how to catch off-specification melting behavior before it turns into a shipping headache.
It’s easy for an outsider to price-shop and assume one supplier is as good as another. The reality is, traders and resellers often have little insight into the day-to-day details that separate a reliable batch from a risky one. Our plant operators know every batch code; analytical teams remember which lot required a special purification tweak. If a customer’s lab needs spectra, certificate of analysis, or even a history of raw material batches, we pull them straight from our database as the original producer.
We’re not just moving product off shelves. We defend every bottle’s lineage, and we own the process from start to finish. Knowing the physical location of every raw material bin and the training level of each operator who handled the aldehyde at each production stage doesn’t just build traceability—it ensures accountability when challenges arise. Because our customers count on the fact that after placing an order, they will get the same result every time.
Facing changing regulations, especially those around hazardous substances and transportation, challenges us to stay proactive. Our regulatory teams keep pace with new safety data sheet requirements, shifting transport classifications, and the ever-changing list of substances tracked in international jurisdictions. There’s plenty of paperwork and red tape, but we bear it to protect our customers’ business and our own.
Supply chain hiccups happen no matter how thorough the planning, yet our direct involvement in production gives confidence in continuity and quality. By keeping synthesis and packaging onsite, with supplies of each intermediate under house control, our team can respond quickly to spikes in demand or short-notice shipping requests. Process optimization isn’t just a quarterly meeting agenda—it’s a direct response to the challenges and lessons we see in daily production. Extensive buffer stocks mean customers rarely face delays due to upstream outages or port slowdowns.
We insist on regular dialogues with supply chain partners so raw material purity never catches us off guard. Spot audits, joint investigations into process changes at suppliers, and frequent cross-checking of documentation reveal issues early. Every year, our team adjusts process parameters and often sources new analytical standards to stay ahead of market trends and regulatory shifts. It’s the discipline and hands-on experience of direct manufacturing that allow us to stand behind the quality of 3,4-Dibromobenzaldehyde through every step.
Long-term partnerships thrive on candor and flexibility. We have worked directly with customer R&D and process teams to troubleshoot issues arising from legacy product, odd impurities, or changing environmental regulations. Small batch customizations, otherwise a nightmare through intermediaries, become a discussion. Whether it’s accommodating different particle sizes, unique packaging, or support with regulatory filings, we sort solutions directly between our teams and customers’ technical staff.
Discussions with industry peers and customers sometimes reveal how easy it is to confuse different brominated benzaldehydes. Many applications call for a specific position of bromine on the benzene ring, and swapping isomers can impact everything from downstream yields to regulatory approval. 3,4-Dibromobenzaldehyde provides unique access to substitution patterns that can’t be accomplished cleanly with 2,4- or 2,5-dibrominated analogues. For example, pharmaceutical developers prefer this product when precise regioselectivity impacts drug candidate safety and synthesis scalability.
Compared with monobrominated aldehydes, our product supplies two bromine atoms at adjacent positions. This increases the range of functional transformations available in metal-catalyzed reactions, broadening structure-activity relationship studies and scale-up feasibility. Customers gain synthetic flexibility, but only if each batch remains uncontaminated with positional isomers or incomplete reagents. Over the years, we invested in optimizing bromination controls to keep double substitution precise and minimize unwanted byproduct formation.
Bulk offerings from generic sources sometimes reach customers poorly labeled or mischaracterized. Misidentified product can derail synthetic plans and lead to months of lost effort in API production or custom synthesis work. Our practices, honed by constant feedback from analytical teams and downstream users, minimize those risks by controlling every critical variable in firsthand. In instances where a product was delayed in transit, we ran rush re-batches with extra QC measures to preserve process timelines.
As a manufacturer, we have seen firsthand how good communication with end-users transforms a supply relationship into a partnership. The journey from raw materials to finished batch means hundreds of small procedures, checks, and adjustments—and responding to challenges as they arise. Collaboration between engineers, logistics staff, plant operators, and customer technical support teams gives real value to buyers—not just a bag of powder, but assurance that challenges in the lab or plant will have a hands-on response.
We value the feedback that keeps our process sharp. Many of the best process changes came from customer requests: non-standard packaging, data sheets with enhanced impurity profiles, or custom particle sizing. Our lab teams stay ready to match analytical techniques and protocols with customer requirements, ensuring not only compliance but reliable performance in the final reaction.
Modern chemical production involves stricter regulations, tighter impurity profiles, and closer scrutiny from both customers and authorities. We’ve adapted to meet these requirements with investment in analytical staff and continuous operator training. Every team member knows their impact on product quality, and no problem leaves the building without hands-on resolution. That tradition supports the ongoing reliability and reputation of our 3,4-Dibromobenzaldehyde.
Our commitment stretches far beyond production and shipping. Technical support from people who have run the exact same equipment, with the same reagents, builds real trust. The conversation doesn’t end with delivery; it keeps going through process development, troubleshooting, and project completion. Direct manufacturer involvement lets us supply more than just raw material—we provide a full-service experience shaped by years of doing the work ourselves.
This chemical isn’t simply a commodity; it’s the result of hundreds of coordinated steps, dozens of trained eyes, and a continuous loop of feedback and improvement. Partners who reach out about process scale-up, impurity profiling, or updated legislation find a responsive team—because we see our customers' deadlines and risks as our own. That approach continues to pay dividends as projects grow and technology evolves across organic synthesis and specialty chemical markets.
Every batch produced builds on the legacy of those before it, incorporating hard-won lessons and anticipating new requirements. Our customers push for more detailed analytical data, lower impurity levels, or unique packaging options—and our team responds to those needs. Experience shows that innovation is less about expensive equipment and more about the people willing to solve problems as they arise. Our technical staff and operators take pride in turning raw materials into reliable product, batch after batch.
The journey hasn’t been without its stumbles. Every plant manager remembers at least one incident where a subtle QC failure or a miscommunication with logistics caused headaches down the line. Those stories drive investments in better training, smarter systems, and more direct communication across production, quality, and customer-facing roles. It’s this clear-eyed view that gives us confidence in the path ahead. We believe thoughtful chemical manufacturing, transparent partnership, and relentless attention to quality allow us to keep leading in the world of 3,4-Dibromobenzaldehyde—across research, industrial, and pharmaceutical markets.