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HS Code |
782816 |
| Name | 3-(4-Chlorophenyl)Glutaric Acid |
| Molecularformula | C11H11ClO4 |
| Molecularweight | 242.66 g/mol |
| Casnumber | 114709-33-2 |
| Appearance | White to off-white solid |
| Meltingpoint | 114-118 °C |
| Solubility | Slightly soluble in water; soluble in organic solvents |
| Purity | Typically ≥98% |
| Smiles | C1=CC(=CC=C1C(CC(=O)O)CC(=O)O)Cl |
| Inchi | InChI=1S/C11H11ClO4/c12-9-4-2-8(3-5-9)6-7(10(13)14)1-11(15)16/h2-5,7H,1,6H2,(H,13,14)(H,15,16) |
| Synonyms | 4-Chlorophenylglutaric acid |
| Storagecondition | Store at room temperature, tightly closed |
| Hazardstatements | May cause irritation to skin, eyes, and respiratory tract |
As an accredited 3-(4-Chlorophenyl)Glutaric Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White, sealed HDPE bottle containing 100 grams of 3-(4-Chlorophenyl)Glutaric Acid; clear labeling with hazard warnings and batch information. |
| Shipping | **Shipping Description:** 3-(4-Chlorophenyl)Glutaric Acid is shipped in tightly sealed, chemical-resistant containers to prevent contamination and moisture ingress. Packages are labeled according to regulatory standards and handled as non-hazardous unless otherwise specified. During transit, the product is protected from extreme temperatures, direct sunlight, and physical damage, ensuring safe delivery to the destination. |
| Storage | Store **3-(4-Chlorophenyl)glutaric acid** in a tightly sealed container, away from moisture and incompatible substances. Keep it in a cool, dry, and well-ventilated area, protected from direct sunlight and oxidizing agents. Ensure proper labeling, and avoid excessive heat or temperature fluctuations. Use suitable secondary containment and follow all local regulations for hazardous chemical storage. |
Applications of 3-(4-Chlorophenyl)Glutaric Acid in Industrial ManufacturingAs a dedicated manufacturer of 3-(4-Chlorophenyl)Glutaric Acid, we supply this specialty intermediate to multiple industrial sectors where process integrity, quality assurance, and material traceability are mission-critical. Each application scenario presented here reflects real, commercially proven use by established downstream producers, specifying the practical requirements for compliance, dosage, integration, and final product classes. 1. Custom Synthesis of Antipsychotic Active Pharmaceutical IngredientsPharmaceutical companies utilize our material as a core building block in the synthesis of certain antipsychotic APIs, where its aromatic-substituted glutaric acid scaffold is indispensable for targeted molecular development. Its reactivity in ring closure and amidation steps directly supports high-yield manufacturing of key intermediates for psychiatric therapeutic compounds, ensuring strict adherence to regulatory specifications at every scale. Industry compliance standards
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2. Specialty Polyester Resin Production for High-Performance CoatingsOur chemical’s bifunctional acid structure provides a route for engineered polyesters with tailored thermal and mechanical properties, meeting stringent performance demands in industrial coatings. Downstream resin manufacturers capitalize on its unique substitution pattern to balance crosslink density and flexibility in powder coating and coil coating resins. Industry compliance standards
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3. Fine Chemical Intermediates for Agrochemical SynthesisProducers of crop protection actives employ this compound as an intermediate in complex, multi-step synthetic pathways to introduce specific aromatic acid motifs required for selectivity in herbicide molecules. Its inclusion enhances process yields and provides a feedstock for downstream halogenation or amide formation chemistry pivotal to modern agrochemicals. Industry compliance standards
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4. Synthesis of UV-Absorbing Monomers for Polymer AdditivesManufacturers of specialty UV-absorber additives target this aromatic-substituted glutaric acid for expansion of their monomer portfolios, using its structure to build new polymerizable UV-shields required in plastics processing. Its compatibility with acrylation and esterification chemistries permits the creation of monomeric components for durable, long-life UV protection in base polymers. Industry compliance standards
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5. Intermediate for Research-Grade Analytical StandardsCertified reference material producers and analytical laboratories use our high-purity material as a precursor to generate analytical standards, calibration targets, and library compounds employed in chromatographic and spectrometric analysis. Its defined substitution pattern and stability under derivatization are critical for low-background, high-sensitivity detection of complex organic residues. Industry compliance standards
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Every successful batch of 3-(4-Chlorophenyl)Glutaric Acid reflects a careful balance between chemistry, craftsmanship, and reliable technology. Over years working in the field, chemists and operators here have honed both process and quality checks to ensure purity, batch after batch. This compound doesn't just represent another line on a product list. It stands as a result of patience in the lab, troubleshooting during scale-up, and answering customers' feedback through design and control improvements.
From raw material qualification to the last drying stage, each step comes under scrutiny. Whether it’s preparing the chlorinated aromatic feedstock or managing temperature ramping during condensation, there are no shortcuts. Systematic monitoring at critical control points and repeated chromatographic checks make certain that the only thing heading out the door is the product customers expect – no more, no less.
Production focuses on pharmaceutical and formulation-grade 3-(4-Chlorophenyl)Glutaric Acid, with purity values that can reach well above 98%. The molecule presents itself as a crystalline white solid, with melting points falling into a narrow, predictable range for consistency in downstream processing. Batch records, sample retention, and lot approval routines are built to withstand scrutiny—whether it’s for clinical trial inputs or high-purity intermediates.
Handling this compound requires more than knowing its structure or functionality. It means having experience with the tricky steps: solvent selection to avoid uncontrolled side-reactions, monitoring chlorination efficiency without residual contaminants, and achieving controlled crystal formation. Our filters, centrifuges, and reactors get checked daily, not just because internal protocols demand it, but because years of work have shown where minor variations can crop up and compromise quality.
We see the differences in practice, not just on paper. Comparisons with other substituted glutaric acids—like 3-(4-Fluorophenyl)Glutaric Acid or unchlorinated glutaric acid—begin with reactivity, stability, and end use. Chlorine on the para position of the phenyl ring alters not just the physicochemical profile but its compatibility with catalysts and co-reactants in certain synthetic pathways.
Other glutaric analogues might produce more side products or require complex purification, slowing down customer production lines. By sticking to a validated recipe and refusing to skip the thorough ending purification, we help formulators eliminate guesswork. Their researchers report smooth transitions to pilot or bench-scale without stuck valves, vessel fouling, or surprise impurity peaks.
This compound doesn’t just fill shelves. Chemists request it by name thanks to its niche fit in pharmaceutical, agrochemical, and specialty chemical syntheses. Its unique backbone provides a versatile starting point for custom chemical entities. Medicinal development teams often put it through the paces in structure-activity studies, aiming to build drug candidates with targeted properties—thanks to that para-chlorinated aromatic group.
Agrochemical development seeks the same backbone for designing new-generation crop protection agents. The compound’s reliable reactivity provides a launching pad for innovation—making it invaluable not only for established products but for exploratory work that sets the next trend. Polymer scientists, too, occasionally turn to glutaric acid derivatives as specialty modifiers, leveraging selective substitution patterns to manipulate flexibility, adhesion, or resistance characteristics in engineered materials.
Feedback from industrial clients continually shapes our approach. One manufacturer switched from an alternative glutaric acid because of recurring solubility issues and batch irreproducibility in their own downstream esters. The tight melting range and dependable assay readings helped them achieve processes with lower downtime and higher product acceptance rates. That explains the steady growth in repeat orders—not from a desire for novelty but from a need for predictability in scale-up.
It’s tempting to talk about reactions, outputs, and innovative potential. Yet, most feedback—especially from higher-regulation markets—centers on purity. The smallest batch-to-batch fluctuation in 3-(4-Chlorophenyl)Glutaric Acid risks not just a spoiled experiment but months of wasted R&D or sudden failures in release testing. To address this, techniques go beyond routine HPLC or melting-point intervals. In-process controls extend to trace impurity mapping and cross-contaminant risk checks, using NMR and finished product certifications to back each claim.
Customers worry about supply chain integrity. Sourcing directly from a manufacturer means questions get answered by the people who run the lines and live with the consequences of each deviation. There’s no finger-pointing to an unknown upstream party or an imported off-grade substitute with murky provenance.
Our technical staff has supported clients through more than a handful of technology transfers and scale-ups involving 3-(4-Chlorophenyl)Glutaric Acid. The margin for error narrows dramatically from milligram bench-scale trials to multi-kilo or tonnage batches. Even by adjusting grind size or blending rates, the handling behavior—from dustiness to dispersion in solvents—calls for attention and adaptation.
Supplying this product means understanding that not all production environments or reactors look alike. Some run closed, automated dispersion systems. Others maintain open manual charging with batchwise heat-up. The compound’s flow, wettability, and reactivity in those setups get flagged as much as its chemical attributes. Engineering support here has learned to translate those needs into physical property targets, and to troubleshoot issues caused by local humidity, storage lag, or pump incompatibilities on site.
Direct conversations have driven batch modifications or, in rare cases, entirely new approaches to drying, sieving, or controlling agglomerates. Feedback cycles don't filter through layers. If something breaks, we hear about it, tweak processes, and document learnings for the future.
A modern facility doesn’t survive without accountability to local and global standards. Sourcing chlorine, aromatic bases, and glutaric acid precursors often presents more of a challenge than the synthesis itself—not all vendors operate with transparency. After hard lessons in traceability, audits now start at purchasing and end at finished-goods dispatch, with strict lot documentation and waste handling.
Clients working in regulated industries rightfully ask for confirmation of environment-friendly practices. Solvent recycling, emissions controls, and scheduled environmental reporting have become standard, not exceptional. In certain years we’ve faced tough capital outlays—installing scrubbers, switching to less hazardous reagents, or automating pH and temperature controls in scrubber and effluent systems. These aren’t “nice-to-haves,” but direct requirements learned from regulatory reviews and conscientious partners. Keeping up drives both trust and long-term supply contracts in pharmaceutical and fine chemical sectors.
Purchasers and scientists come with very different backgrounds and demands. Both benefit from honest discussion about scale, packaging, and transport. Lab-scale R&D procurement involves flexibility: smaller glass bottles, tamper-evident seals, and custom weights. Large-scale production means pallet shipments, custom drums, or nitrogen-flushed liners to protect from moisture pickup. Insulation or desiccant options prevent caking during transit under fluctuating temperatures. Such choices come out of hard-won experience dealing with customer complaints and logistics hitches.
From the manufacturer’s side, we retain samples from each lot, storing them under real conditions—so we’re ready to investigate if a deviation shows up downstream months later. There’s no glossing over the pressure to keep records airtight when each customer’s workflow may stretch a single lot’s life cycle for years. Re-lotting, certificate re-issues, and stability reruns sometimes become part of the job, not just an afterthought.
Not every product runs flawlessly, especially in new applications. One pharmaceutical development team reported unexpected color changes post-reaction, which prompted a full-scale inquiry on both sides. Trace residuals in an incoming raw material lot, invisible to initial screens, did the damage. The only way to solve it required both laboratory investigation and improvements to supplier vetting—plus a practical change to internal sampling and analysis on every new batch of that input. These experiences inform decisions and prevent repeat problems.
Other times, a customer’s breakthrough validates the extra effort. Medicinal chemists who used a competing supplier’s version noticed recurring process delays due to sticky residues appearing late in synthesis—slowing filtration and raising questions in QA. Switching to our product, made under narrower process conditions, cut cycle times and let the client recover more material per batch. In such instances, technical teams from both firms share findings and adapt protocols. When those adjustments close a loop between procurement, R&D, and plant operations, the relationship strengthens for future collaborations.
Our production team doesn’t stand still. Each lot of 3-(4-Chlorophenyl)Glutaric Acid moves through stages refined by dozens or hundreds of micro-adjustments prototypes. Operator logs and feedback cycles mean that knowledge from experienced hands passes to new staff. Whether adapting new mixing patterns to change crystal habit or adjusting agitation rates to prevent clumping, lessons become part of daily routines—not just theoretical ideals.
Day-to-day, even the most robust process can benefit from technical dialogue with users. Some customers have challenged our assumptions about particle size, wettability, or certain color spec tolerances—leading us to conduct extra studies in the pilot facility. Their insights help align product, packaging, and technical support for each new market or application. Together with recurring feedback from regulatory or external auditors, this steady exchange maintains momentum for product and process optimization.
Recent years have seen sharp changes in global supply chains. Border disruptions, raw material price spikes, and geopolitical shifts all pushed chemical companies toward redundancy and manufacturing control. Customers no longer accept vague promises on source traceability or “gray market” intermediates.
Supplying 3-(4-Chlorophenyl)Glutaric Acid as a direct manufacturer means standing behind every metric ton shipped out as if it will power our clients’ biggest breakthroughs. From secured batch tracking to direct communication on lead times, dock schedules, and potential disruptions, credibility always depends on facts, not marketing spin. Operations staff, supply chain specialists, and senior leadership all share in this responsibility.
Where others might opt for third-party sourcing or “white-label” approaches, the commitment here leans into full transparency. Every pick, blend, and shipment traces back to teams accountable for the outcome. That means direct answers, timely corrections if necessary, and ongoing honesty about what’s possible within current infrastructure and what might require new investment.
Innovation in the specialty intermediates market never lets up. User groups are exploring new uses for glutaric acid derivatives. Biotransformations in pharmaceutical precursors, specialty coatings, and environmentally safer formulations all challenge traditional chemistries. As regulations change, the demand for better impurity control, greener methods, and improved operators’ safety will only grow.
Here, we keep one eye on current production loads, and another on new routes that might use less hazardous reagents, offer higher selectivity, or deliver more robust handling characteristics for customer plants. Investments in automation, simulation-based process controls, and advanced monitoring respond not just to costs, but to the realities of leaner teams and increased audit expectations worldwide. Customers who engage early and openly with production partners often get the jump on rivals—and manufacturers who pay attention to evolving needs carve out their own reputations for reliability and innovation.
3-(4-Chlorophenyl)Glutaric Acid production isn’t a sideline. It’s a product leveraged daily by developers racing toward new medicines, safer crop solutions, or novel engineered materials. We know from experience that what counts isn’t just the product’s chemical structure or a box ticked on a datasheet. The real relationship forms when customers see consistent, traceable shipments, and responsive technical support when needs change or problems arise.
Downtime isn’t an abstract metric on a report; it translates to missed deadlines and blown budgets. Supplying a predictable, high-purity intermediate makes it easier for customers to plan, develop, and deliver in turn. Our commitment to direct manufacturing means every step gets attention, every inquiry a prompt and honest reply, and every shipment stands as proof of our investment in expertise, quality, and support.
In a world where shortcuts and half-measures carry steep risks for innovation and market leadership, sticking to the fundamentals of process reliability and hands-on quality control gives both producers and users safer ground to stand on. For every batch of 3-(4-Chlorophenyl)Glutaric Acid that leaves our facility, that conviction gets tested all over again—and year after year, it’s proven its worth to partners who demand the right balance of chemistry, trust, and practicality.