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3,3-Dimethyl-1-Butanol

    • Product Name 3,3-Dimethyl-1-Butanol
    • Alias 3,3-DMB
    • Einecs 211-225-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    466064

    Iupac Name 3,3-Dimethyl-1-butanol
    Molecular Formula C6H14O
    Molar Mass 102.17 g/mol
    Cas Number 595-85-5
    Appearance Colorless liquid
    Boiling Point 123-125 °C
    Melting Point -60 °C
    Density 0.803 g/cm³
    Solubility In Water Slightly soluble
    Flash Point 30 °C
    Refractive Index 1.412
    Pubchem Cid 10556

    As an accredited 3,3-Dimethyl-1-Butanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 3,3-Dimethyl-1-Butanol is packaged in a 100 mL amber glass bottle with a secure screw cap, labeled for laboratory use.
    Shipping 3,3-Dimethyl-1-Butanol is shipped in tightly sealed containers to prevent leakage or contamination. It should be stored in a cool, dry, and ventilated area, away from sources of ignition. Appropriate labeling and documentation must accompany the shipment, and handling must comply with all relevant chemical transportation regulations and safety guidelines.
    Storage 3,3-Dimethyl-1-butanol should be stored in a cool, dry, well-ventilated area away from sources of ignition and incompatible materials such as strong oxidizers and acids. Keep the container tightly closed when not in use. Store in a chemical-resistant, labeled container. Protect from moisture and direct sunlight. Follow all standard laboratory safety and chemical storage guidelines.
    Application of 3,3-Dimethyl-1-Butanol

    Applications of 3,3-Dimethyl-1-Butanol in Industrial Manufacturing

    3,3-Dimethyl-1-Butanol is a high-purity aliphatic alcohol widely applied as a functional building block and specialty additive across selected downstream industrial processes. Our direct manufacturing experience supports scale-up requirements for advanced materials, performance chemicals, and specialty intermediates in accordance with strict sectoral standards. The following sections outline real-world, compliance-focused application scenarios, referencing batch integration, dosage, certification alignment, and resulting end-use products.

    1. Synthesis of Pharmaceutical Intermediates

    Leading pharmaceutical manufacturers employ 3,3-Dimethyl-1-Butanol in the synthesis of tailor-made intermediates for APIs, particularly through Grignard and alkylation reactions. Its sterically hindered structure introduces specificity in preparing β-branched alcohols and custom side-chains, supporting medicinal chemistry projects where controlled purity and reproducibility are critical for downstream drug substance development.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF (United States Pharmacopeia - National Formulary) guidelines for excipients and raw material authentication
    • EU GMP Part II (API manufacturing standards)

    Typical usage ratio

    • 0.5–5 mol% of target intermediate mass, according to target synthetic step complexity and protection group strategy
    • Fine-tuned based on route optimization and batch yield analysis

    Downstream process integration

    • Added post-activation during alkyl group installation in multi-step API synthesis
    • In-line solvent replacement or direct addition in Grignard/organometallic couplings

    Final product types

    • Pharmaceutical intermediates bearing isobutyl or β-branched side chains
    • Building blocks for anti-infective or CNS drug syntheses
    • Custom monomers for advanced prodrug production

    2. Production of Fragrance and Flavor Intermediates

    Fine fragrance and flavor compound producers use 3,3-Dimethyl-1-Butanol as a precursor for creating specialty esters and high-impact aroma ingredients. Its branched structure provides a unique molecular motif, resulting in specialty base notes and branching in ferments or reaction with acid chlorides to yield proprietary signature ingredients for formulated compounds.

    Industry compliance standards

    • IFRA (International Fragrance Association) Code of Practice
    • FEMA (Flavor and Extract Manufacturers Association) GRAS status confirmation for downstream materials
    • ISO 9235: Natural Aroma Chemicals identification guidelines (for semi-synthetic derivatives)

    Typical usage ratio

    • 1–10% by weight in esterification batches, depending on target aroma strength and volatility requirements
    • Adjusted lower for potent base note formulations

    Downstream process integration

    • Direct batch inclusion for esterification with C2–C8 acid chlorides
    • Fed during perfumery intermediate synthesis in multi-reactor lines

    Final product types

    • Isobutyric or oxo-ester fragrance molecules
    • Keynotes for high-value fine fragrance bases and controlled-release flavor systems
    • Intermediate bulking agents in synthetic musk and specialty aroma compound production

    3. Manufacture of Polymer Modifiers and Plasticizers

    Specialty polymer producers utilize 3,3-Dimethyl-1-Butanol as a key modifier for designing branched plasticizers and reactive diluents, improving flexibility, migration resistance, and molecular weight distribution in PVC, acrylics, and polyolefin-based compounds. Its highly branched structure enhances compatibility with phthalate alternatives and green plasticizer formulations that must meet regional regulatory demands.

    Industry compliance standards

    • REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals)
    • RoHS (Restriction of Hazardous Substances Directive) for electrical plastics
    • EN 71-3: Safety of Toys – migration of certain elements (for flexible toys and consumer products)

    Typical usage ratio

    • 5–20 phr (parts per hundred resin) in plasticizer blends, subject to migration and mechanical property targets
    • Specific adjustment based on resin compatibility and processing method (extrusion or injection molding)

    Downstream process integration

    • Added during melt blending or pre-emulsification with primary plasticizers in heated mixing vessels
    • Introduced as monomer chain extender in specialty acrylic resin reactors

    Final product types

    • Flexible PVC sheets, films, and cable coatings
    • Phthalate-free and non-toxic children’s toy polymers
    • Modified acrylic resins for adhesives and impact modifiers

    4. Production of Industrial Lubricant Additives

    In the specialty lubricant sector, formulators incorporate 3,3-Dimethyl-1-Butanol as a high-temperature additive precursor, synthesizing esters and derivatives that enhance lubricity, oxidation stability, and pour-point properties in both synthetic and mineral oil blends. Its structure generates low-foaming and hydrolytically stable lubricant components, supporting demanding industrial requirements such as those in compressor, gear, and turbine oils.

    Industry compliance standards

    • DIN 51517: Lubricants - Lubricating oils - Minimum requirements
    • ASTM D445/D97: Kinematic viscosity and pour point specifications for industrial oils
    • ISO 6743: Lubricants, industrial oils and related products classification

    Typical usage ratio

    • 0.25–2% by weight as a co-additive precursor in high-performance lubricant bases
    • Optimized via bench testing for viscosity and volatility profiles

    Downstream process integration

    • Charged to esterification reactors with C8–C10 acids during synthesis of diester or polyol ester stocks
    • Blended in additive packages supplied to bulk oil formulators or toll blenders

    Final product types

    • Synthetic compressor and hydraulic oils
    • High-stability gear and turbine lubricants
    • Performance-grade food machinery oils (where incidental contact approval is required)

    5. Custom Synthesis for Crop Protection Active Ingredients

    Leading agrochemical syntheses utilize 3,3-Dimethyl-1-Butanol as a hydrocarbon backbone for selective functionalization, introducing steric bulk in herbicide and insecticide intermediates. Downstream customers leverage its properties to drive activity in target-specific molecule construction, with final actives deployed in regulated agricultural environments requiring traceability and compliance with environmental standards.

    Industry compliance standards

    • FAO/WHO Specifications for Pesticides
    • OECD Principles of Good Laboratory Practice (GLP)
    • EPA 40 CFR Part 180: Tolerances and Exemptions for Pesticide Chemical Residues

    Typical usage ratio

    • 0.8–6 mole% relative to the agrochemical active batch, optimized via active ingredient synthetic route development
    • Adjusted to ensure minimal side product contamination and regulatory residual limits

    Downstream process integration

    • Introduced in controlled addition stages for etherification or alkylation within multi-functional group syntheses
    • Utilized in pilot and full-scale batch reactors with continuous QC monitoring

    Final product types

    • Precursor blocks for novel herbicide and insecticide actives
    • Branched chain intermediates used in crop protection formulation design
    • Bulk technical-grade agrochemical substances for further formulation
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    Certification & Compliance
    More Introduction

    Introducing 3,3-Dimethyl-1-Butanol from a Chemical Manufacturer’s Perspective

    What Sets 3,3-Dimethyl-1-Butanol Apart in Day-to-Day Production

    Within our own production lines, 3,3-Dimethyl-1-Butanol stands out due to its distinct structural profile and versatility on the plant floor. The compound belongs to the family of aliphatic alcohols, featuring a branching at the third carbon with two methyl groups. This subtle modification sounds simple, yet it gives this alcohol qualities that regular butanols and other linear or branched alcohols just don’t show during reactions.

    From the moment the raw materials enter our facility, we choose 3,3-Dimethyl-1-Butanol for processes that require a balance of reactivity and chemical stability. Its molecular arrangement, specifically the dual methyl branching, gives the molecule lower water solubility than its less-branched siblings. In the reactor, this makes it favor certain organic-phase reactions, which we have used to our advantage in developing specialty intermediates and custom applications for clients in coatings, fragrances, and even advanced electronics.

    Why 3,3-Dimethyl-1-Butanol Earned a Spot on Our Line

    Over years of batch runs, we found the slightly higher boiling point lets us isolate it efficiently by fractional distillation. Each batch yields a pure, colorless liquid with the consistent faint, pleasant odor that characterizes this alcohol. Chemically, it resists unwanted side-reactions compared with standard 1-butanol or even tert-butanol, avoiding headaches during downstream applications.

    Our team keeps a close watch on purity since contaminants shift product performance during esterification and other key steps. Typical shipments meet minimum purity above 98%, leaving little room for process upsets or customer setbacks. In-house, we test for water content by Karl Fischer titration, making sure low moisture levels suit moisture-sensitive syntheses in the lab.

    Common Usage in Manufacturing: Field Lessons

    What really drives our enthusiasm for 3,3-Dimethyl-1-Butanol is its usability. We do more than just ship drums — we go hands-on to scale up formulations for clients, adjusting blends until their process hits production targets. While linear butanols sometimes cause gelling or reaction delays, the additional branching means our customers report smoother, more predictable mixing, especially in complex organometallic syntheses.

    For resin manufacturers, this product serves as a dependable chain stopper, controlling molecular weights during the production of specialty acrylics and polyesters. Its volatility profile lets it evaporate slowly enough during film formation, reducing issues with surface defects or pinholes — a recurring problem with lighter, more volatile alcohols.

    In the fragrance business, its mild odor and chemical backbone let perfumers and R&D labs build new molecules with a crisp, clean note that we haven't matched with simpler C4 or C5 alcohols. Our clients reference its value as a building block for both bulk intermediates and highly specialized aroma compounds. Most alcohols in this size range either linger too heavily or bring a greasiness that limits creative formulas. 3,3-Dimethyl-1-Butanol finds the right middle ground.

    Real-World Performance and Material Handling

    Handling materials at scale means we develop a close relationship with their quirks. 3,3-Dimethyl-1-Butanol flows smoothly through our drum pumps and doesn’t clog transfer hoses, even during cold weather operations. The viscosity remains manageable below room temperature, so plant teams swap fittings without fuss or the need for external heating.

    From a safety and compliance angle, our safety teams appreciate its higher flash point compared to n-butanol, which lets us reduce ventilation needs and improve storage flexibility in the warehouse. We use closed transfer systems to reduce vapor exposure. The vapor itself carries less risk than low-boiling alcohols such as isopropanol, though our teams never lose sight of the need for basic PPE and vapor monitoring in the tank farm and filling lines.

    Comparing 3,3-Dimethyl-1-Butanol With Other Alcohols on the Market

    Colleagues from purchasing always ask why this alcohol justifies the extra cost against commodity butanol or 2-ethylhexanol. Our answer comes back to process reliability and downstream quality. Linear four-carbon alcohols, for all their low cost, sometimes plug filters or form azeotropes with solvents, throwing off separation steps. 3,3-Dimethyl-1-Butanol sidesteps these pitfalls due to its branching, offering easier purification and more straightforward analytics by gas chromatography in QC.

    As a manufacturer, troubleshooting means everything. Simple linear isomers sometimes react too quickly or produce unstable by-products, especially under catalytic conditions or extended processing. Through side-by-side runs, 3,3-Dimethyl-1-Butanol shows cleaner conversions in select oxidation and esterification routes, leading us to recommend it for pilot-scale reactions that require tighter control and fewer by-products. Over time, feedback from the field has shown improved product yields and simpler downstream processing.

    Even in catalyst wash or scavenging steps, the alcohol’s sterics favor selectivity, so yield loss due to side-reactions or unplanned reactivity stays lower than with n-butanol or tert-butanol. Resin producers say batch-to-batch consistency improves, while coatings manufacturers highlight fewer instances of skinning or haze in finished products.

    Supporting Sustainability Goals in Daily Operations

    Demand for greener chemistry grows every year, and we noticed that 3,3-Dimethyl-1-Butanol fits into solvent-recovery cycles better than longer-chain alcohols. Its resistance to oxidation and moderate vapor pressure let us set up solvent reclaim units that run with lower energy input and less off-gas. Plant-level data confirm more product stays in the system and recycles for second and third runs, reducing vessel cleanout frequency and hazardous waste.

    Compared with other short-chain alcohols, the slightly higher molecular weight offers improved separation via distillation—meaning less energy used in the plant utility room and fewer carbon emissions per ton of product shipped. Colleagues working on our green-chemistry task force use this alcohol as an example of incremental environmental improvement without sacrificing process efficiency or finished product consistency.

    Field Feedback and Customer Experience

    After multiple customer audits and technical reviews, we see a high degree of process satisfaction. Blenders using continuous reactors claim they can run longer between maintenance cycles. In high-shear mixing operations, the alcohol doesn’t foam or entrain air to the degree seen with primary butanols. That reliable behavior reduces adjustment cycles, maximizing uptime and saving costs on antifoam additives.

    We work regularly with application specialists in paints and coatings. They value the alcohol’s compatibility during both batch and continuous production runs. Coating films build uniform gloss and hardness, with as-tested data showing fewer imperfections in cross-hatch adhesion trials. Users on the line comment on the improved wet edge and drying consistency, especially in climate-controlled facilities.

    Problems Encountered and Solutions Developed

    Manufacturing is rarely trouble-free. During a major expansion eight years ago, our reactors ran into a phase-separation issue that hampered ester production using a competitor’s lower-grade dimethyl-butanol variant. After a root-cause analysis, we traced the problem to subtle isomeric impurities. Updated purification strategies for 3,3-Dimethyl-1-Butanol eliminated the trouble, restoring reliable yields.

    We have had cases where customers struggled with older pump seals, designed for pure linear alcohols. Our technical team advised swapping to upgraded elastomers suitable for slightly more hydrophobic molecules, solving swelling and service life complaints. Storage tanks require sealed systems, as with most alcohols, but maintenance issues dropped since minor evaporation losses and odor emissions decreased.

    Regulatory Observations and Handling Documentation

    With evolving environmental and workplace safety regulations, our compliance managers updated documentation to reflect the alcohol’s relatively low toxicity profile, benchmarked against other aliphatic and branched alcohols used in solvents or synthetic intermediates. Local authorities have not flagged issues related to storage or offsite transport, as our certified drums and containers meet hazardous material codes where appropriate.

    In downstream applications, customers receive tailored advice on labeling, waste treatment, and spill management. Our approach to regulatory support draws from years of audits, demonstrating clean handling histories and robust containment infrastructure. Certificates of analysis and batch-specific reports always travel with outbound shipments.

    Supply Reliability and Production Capacity

    Maintaining uninterrupted supply weighs on every manufacturer's mind. Production planning in our facility builds resilience into every run—holding raw material stocks, investing in reliable upstream partners, and scheduling preventive maintenance on reactors and distillation columns. We added new capacity recently, resulting in steady batch turnover and shorter delivery lead times for regional and international clients.

    Customers know our stock strategies, and we welcome multiyear volume commitments to align production schedules with downstream demand cycles. Buffer inventory policies absorbed recent logistics shocks, keeping downstream operations on track even through regional transport delays or port congestion. Our partners trust us because service interruptions rarely occur.

    Supporting Partner Innovation and Joint Projects

    Discovery projects and joint development keep our technical teams running at full tilt. Frequent collaborative pilots introduce new uses for 3,3-Dimethyl-1-Butanol—from advanced surfactant cores to fine chemical intermediates for electronics. Early engagement with R&D specialists means they access process-scale volumes, not just lab samples, speeding up new product validation in real-world conditions.

    Research partners give us honest, rapid feedback. If formulating issues surface, our chemists adjust process routes and purity grades to maintain compatibility with downstream catalysts or sensitive polymers. Direct involvement in scale-up tests ensures the alcohol behaves as intended under demanding commercial conditions—years of experience have shown that this close dialogue makes a difference between project success and costly delays.

    Looking Ahead: Trends and Future Applications

    During the last decade, changes in material science and regulations shaped the kind of chemistries we see in everyday operations—from bio-based plastics to environmentally regulated coatings. 3,3-Dimethyl-1-Butanol now draws more attention in high-performance applications because it avoids legacy issues like unwanted side-reactions and hard-to-separate by-products.

    The emergence of new process technologies, such as continuous flow reactors and on-demand formulation plants, has created fresh demand for precision building blocks. Our in-plant experience with 3,3-Dimethyl-1-Butanol means we anticipate and support these shifts, offering scalable supply, real-world technical data, and access to application experts who roll up their sleeves to solve production challenges alongside our clients.

    Conclusion: Manufacturer Commitment to Quality and Continuous Improvement

    Reliability, process insight, and detailed quality management go into every shipment of 3,3-Dimethyl-1-Butanol. Daily routines at the plant fuse decades of chemical know-how with a practical understanding of shifting industry and regulatory needs. We take pride in the way our product fuels downstream innovation—whether it's lower emissions in solvent recovery, improved film properties in coatings, or efficient chain stopping in polymer synthesis.

    Success with specialty chemicals depends on more than just delivering a molecule. It means listening to user feedback, fixing problems fast, and adapting plant operations as applications change and technology advances. Our experience with 3,3-Dimethyl-1-Butanol stands as a case study in how technical capability, plant diligence, and customer partnership forge a product that does more than fill a drum—it builds new opportunities, process reliability, and trust, batch by batch.