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3-(2-Hydroxyethoxy)Benzaldehyde

    • Product Name 3-(2-Hydroxyethoxy)Benzaldehyde
    • Alias 3-(2-Hydroxyethoxy)benzenecarbaldehyde
    • Einecs 242-950-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    332356

    Productname 3-(2-Hydroxyethoxy)Benzaldehyde
    Casnumber 29885-09-8
    Molecularformula C9H10O3
    Molecularweight 166.18 g/mol
    Appearance Colorless to pale yellow liquid
    Purity Typically ≥ 98%
    Boilingpoint 145-147°C at 2 mmHg
    Density 1.183 g/cm³
    Solubility Soluble in organic solvents such as ethanol and DMSO
    Flashpoint 124°C
    Smiles C1=CC(=CC(=C1)OCCO)C=O
    Inchikey LZYYTFSKGCUFHC-UHFFFAOYSA-N

    As an accredited 3-(2-Hydroxyethoxy)Benzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 3-(2-Hydroxyethoxy)Benzaldehyde is supplied in a sealed amber glass bottle with a tamper-evident screw cap.
    Shipping **Shipping Description:** 3-(2-Hydroxyethoxy)Benzaldehyde is shipped in tightly sealed containers, protected from light and moisture. The packaging ensures stability and prevents leakage. It is transported as a non-hazardous chemical under standard conditions, but care is taken to avoid extreme temperatures and incompatible substances. Safety data sheets accompany each shipment.
    Storage Store **3-(2-Hydroxyethoxy)benzaldehyde** in a tightly sealed container, in a cool, dry, and well-ventilated area away from direct sunlight and incompatible substances such as strong oxidizing agents. Keep it at room temperature, avoiding exposure to moisture and heat. Properly label the container and ensure it is out of reach of unauthorized personnel, following all relevant safety guidelines.
    Application of 3-(2-Hydroxyethoxy)Benzaldehyde

    Applications of 3-(2-Hydroxyethoxy)Benzaldehyde in Industrial Manufacturing

    3-(2-Hydroxyethoxy)Benzaldehyde is a specialty chemical intermediate broadly used in regulated industrial manufacturing processes. The following sections detail authentic downstream applications, with dedicated requirements, ratios, integration methods, and resulting finished products, reflecting best practices and real-world manufacturing standards.

    1. Synthesis of Pharmaceutical Intermediates

    Manufacturers in the pharmaceutical sector adopt this material for precise functionalization in heterocyclic compound synthesis. This compound acts as a vital building block during the production of advanced pharmaceutical intermediates, where strict traceability and structural selectivity are critical. Integration takes place at the condensation or coupling stage with amines or hydrazines to yield specific active pharmaceutical ingredient (API) precursors, guided by validated batch protocols and comprehensive impurity profiling.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 210/211
    • EU EudraLex Volume 4 Annex 1
    • Ph. Eur., USP monographs for intermediates

    Typical usage ratio

    • Usually 0.7%–2.5% w/w relative to main reactant, adjusted by reaction pathway and target purity profile

    Downstream process integration

    • Introduced during early-stage step-growth or condensation reactions in controlled reactor vessels, followed by phase separations and chromatographic purification of resulting intermediates

    Final product types

    • Benzimidazole-based APIs
    • Cephalosporin intermediates
    • Pyridine and isoquinoline derivatives
    • Regulated pharmaceutical building blocks

    2. Fine Fragrance and Aroma Chemical Manufacture

    The material sees critical use in the fragrance sector, particularly for aldehyde notes and complex floral scent composition. It is employed during the synthesis of aroma ingredients intended for high-grade perfumery, where it brings distinct olfactory properties through selective acetalization, reduction, or etherification. Documentation and process control govern its application, especially where supply chain transparency and residual solvent controls are vital.

    Industry compliance standards

    • IFRA Guidelines and Standards
    • REACH (EC No. 1907/2006) for chemical safety
    • ISO 9001:2015 Quality Management for production consistency
    • Certificate of Naturalness traceability for aroma compounds

    Typical usage ratio

    • 1.2%–5.5% in core aroma compound synthesis; level depends on target olfactive intensity and formulation stability

    Downstream process integration

    • Combined with alcohols or ketones at the aroma molecule formation stage, followed by vacuum distillation and deodorization phases

    Final product types

    • Specialty fragrance aldehydes
    • Floral or herbaceous aroma bases
    • High-value perfumery blends
    • Custom aroma compound ranges for consumer products

    3. High-Performance Polymer Synthesis

    Chemical companies in advanced materials use this benzaldehyde derivative for engineering polymer resin production, where functionalized aromatic aldehydes enhance cross-linking density and thermal resistance. It enters formaldehyde-free thermoset or thermoplastic formulations, supporting the creation of polymers with tailored mechanical properties for demanding end-use applications.

    Industry compliance standards

    • ISO 14001 Environmental Management
    • RoHS Directive 2011/65/EU for restricted substances
    • ANSI/ASTM D638 for polymer tensile properties
    • UL 94 for flammability of plastic materials

    Typical usage ratio

    • 0.3%–1.8% relative to base monomer mass, optimized for target polymer cross-linking features and viscosity

    Downstream process integration

    • Added at pre-polymer mixing or initial monomer charging, undergoing in-situ coupling and subsequently cured under controlled temperature and pH

    Final product types

    • Epoxy and phenolic resin additives
    • Polyester and polyamide enhancement agents
    • Insulation film coatings
    • High-heat-resistant composite plastics

    4. Advanced Dye and Pigment Manufacturing

    The field of dyes and colorants includes the use of this raw material as a key intermediate in synthesizing ether-based chromophores and Schiff base pigments. Industrial users integrate it to achieve precise color tuning, solubility, and stability in both liquid and powder dyes. Its inclusion takes place in the downstream coupler synthesis or diazotization processes under closely monitored batch QC protocols and waste minimization practices.

    Industry compliance standards

    • REACH compliant safety and registration
    • OEKO-TEX® Standard 100 for textile chemicals
    • ISO 18314 for analytical colorimetry in pigment productions
    • APEO-free formulation certification

    Typical usage ratio

    • 1.0%–4.0% based on dye batch weight; level tailored according to desired color shade and stability targets

    Downstream process integration

    • Reacted into Schiff base or ether-functionalized dye intermediates, typically in aqueous phase or non-aqueous solvents, before downstream post-purification and powderization

    Final product types

    • Reactive textile dyes
    • Specialty printing ink pigments
    • High-performance organic colorants for plastics
    • Fluorescent marking agents
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    Certification & Compliance
    More Introduction

    Introducing 3-(2-Hydroxyethoxy)Benzaldehyde: Experience from the Manufacturing Floor

    Crafting Quality: What Sets Our 3-(2-Hydroxyethoxy)Benzaldehyde Apart

    Stepping into the chemical production plant every morning means facing the precise nature of molecules and watching batches move from raw materials to pure, reliable products. We’ve been making 3-(2-Hydroxyethoxy)Benzaldehyde for years, growing alongside our customers who need consistent results. Our team handles each process, standing beside the reactors, smelling the change in the air as the aldehyde group forms. The chemical’s IUPAC name might sound complicated, but its value is clear for anyone using it as an intermediate in pharmaceutical, fragrance, or specialty chemical synthesis. Unlike materials shuttled around networks of traders, ours comes straight from the manufacturer’s pipeline, handled with attention that only comes from people doing the hard work.

    3-(2-Hydroxyethoxy)Benzaldehyde carries the formula C9H10O3, and if you look at the molecule, you’ll spot both the benzaldehyde and ethylene glycol backbone. Blending these two functionalities opens up possibilities for downstream chemistry. Whether the goal involves further oxidation, condensation, or forming novel derivatives, having steady supply quality changes how laboratories and plants plan projects. We produce this compound with careful control of temperature, pressure, and purity, batch after batch. Each drum reflects adjustments born of troubleshooting during scale-up. If oddities in color or residue appear, we figure them out fast, using analytical equipment most labs would envy.

    For those exploring aldehyde chemistry, not all forms deliver the same results. The presence of the 2-hydroxyethoxy group on the benzene ring makes this product different from simple benzaldehyde or other hydroxy-substituted analogues. That extra flexibility increases solubility and supports new reaction types. Many customers use this property to drive efficiency in synthesis steps, bypassing problems seen when working with plain benzaldehyde, which can prove unwieldy or prone to unwanted side reactions. This subtle shift in molecular design enables access to unique intermediates and a tailored approach to functional group management.

    Purity as a Reflection of Production Experience

    Crafting consistency in organic synthesis remains a constant challenge. Impurities linger from starting materials, traces of solvents, or reaction byproducts. In our line, we’ve learned that even minor inconsistencies in the feedstock spell trouble weeks later once downstream chemists spot small changes in yield or spectral purity. That realization pushed us to invest in better distillation columns, higher efficiency filtering, and chromatographic checks to trim impurities below legal and industry thresholds. Customers working in active pharmaceutical ingredients pay attention to trace impurities, and even those making flavors can’t afford off-notes.

    We can’t claim the highest purity because we’ve stumbled on the same batch-to-batch quirks as everyone else in this line of work. Instead of hiding them, we spent years tweaking our cleaning cycles, solvent rinses, and filtration routines. These improvements didn’t happen overnight; they came through close collaboration between production, laboratory, and maintenance crews. Whenever complaints surfaced, we tracked problems to their source rather than offering empty assurances. Those hard lessons now live in the product we supply. Our 3-(2-Hydroxyethoxy)Benzaldehyde typically achieves purity suitable for both pharmaceutical and industrial synthesis, minimizing common contaminants that could compromise sensitive downstream applications. This reliability, honed through cycles of hard work and problem-solving, makes a difference in the hands of end users.

    Usage in Synthetic Chemistry: Real-World Applications

    As chemists and manufacturers ourselves, we’ve watched this aldehyde travel through pipelines into new medicines, polymer modifiers, and specialty scents. In many drug discovery programs, the molecule pops up at the crossroads of library generation—building blocks designed for rapid diversification. Its bifunctional nature, with both the reactive aldehyde and hydroxyethers, broadens the scope for structural elaboration. Real users talk about improved yields when employing this compound instead of less soluble analogues. Whenever a customer shares a successful scale-up story involving 3-(2-Hydroxyethoxy)Benzaldehyde, that feedback circles back through our plant. It validates the focus we’ve placed on keeping water content and trace byproducts low.

    This compound does not behave like simpler aldehydes in every context. The hydroxyethoxy substituent imparts higher polarity, which changes solubility profiles in polar and nonpolar media. Chemists using it for condensations or Wittig reactions note shorter reaction times and fewer unpleasant surprises during product isolation. It also enjoys use in the synthesis of ethers and esters where adjacent hydroxyl groups bump up reactivity toward selective transformations. This means less time spent fighting solubility problems, lower material loss, and often cleaner product streams.

    Differences From Other Benzaldehyde Derivatives

    Choices in starting materials make or break many projects, especially in scale-up and manufacturing. 3-(2-Hydroxyethoxy)Benzaldehyde differs noticeably from the typical suite of benzaldehydes in direct application and process handling. Introducing a hydroxyethoxy group changes how the molecule interacts with other reactants. This is not an abstract benefit—it translates into real reductions in reaction times and the ability to carry out steps under milder conditions. Those attempting similar transformations with simple benzaldehyde or p-hydroxybenzaldehyde usually encounter additional stages just to dissolve salts or handle sticky intermediates. We see far fewer troubleshooting calls when teams start with our material versus more generic aldehydes.

    By the time an organic chemist chooses a substituted benzaldehyde, they already have a path in mind that depends on clean and predictable reactivity. One of the most commonly cited frustrations from users switching from generic products to ours centers around reproducibility. Reproducibility isn’t just about the chemical itself, but also about not wrestling with contaminants or having to re-optimize purification columns for every order. We run frequent GC-MS, HPLC, and NMR tests to ensure no drift in quality from one batch to the next. Open communication between production and R&D teams lies behind this steadiness.

    On a practical level, changes in the substituent pattern influence both storage and transport. Our 3-(2-Hydroxyethoxy)Benzaldehyde, with its moisture-absorbing side group, packs tighter and resists volatilization better than unsubstituted benzaldehyde. That reduces product loss and makes bulk handling safer and less wasteful. We load every drum and tote with this experience in mind, lining and sealing units so customers get the full weight and expected performance. The value lies not just in the molecule, but in the layers of knowledge and experience protecting it from the hazards of real-world shipping and storage.

    Building Trust: Open Lines of Communication and Learning

    Manufacturing puts people face to face with all the things that can go wrong long before any finished product ships out. Our experience with 3-(2-Hydroxyethoxy)Benzaldehyde has taught us that building trust starts with sharing both successes and difficulties, and then putting in the work to address every issue. Too often, the wider specialty chemical market suffers from a lack of transparency. Materials change hands multiple times, specs get trimmed, and suddenly chemists confront product that looks fine on a sheet but acts differently in the flask. By producing this aldehyde ourselves, monitoring each stage, and supporting users directly, we build a feedback cycle that keeps quality in check.

    Our customer base includes pharmaceutical firms, R&D outfits, polymer specialists, and aroma compound makers. Each group raises unique challenges. Drug manufacturers demand the tightest impurity controls and documentation to meet global regulatory scrutiny. Fragrance companies get directly impacted by faint traces of aromatic impurities, which can change the scent profile on a batch-to-batch basis. Users in the plastics space care less about trace scents, but more about consistency and manageability in large-scale applications. Our team learns from these distinct needs by adjusting process controls and sharing modifications with end users willing to offer detailed technical feedback.

    Pushing for Better: Solutions to Common Industry Pain Points

    Plenty of complaints reach us about other benzaldehyde-derived compounds. Some users struggle with unexpected color changes, sticky residues, or storage problems. Many of those problems trace either to poor purification, inconsistent starting materials, or careless handling in warehouses. Having confronted each one at our own site, we’ve found that day-to-day observation—sample by sample—matters. Our staff regularly checks barrels and storage tanks for off-odors, discoloration, or changes in viscosity. Sampling doesn’t end once a batch leaves the reactor; it continues in the warehouse and loading dock. Each anomaly leads directly to hands-on troubleshooting and, if needed, adjustments to purification steps or even the supply chain feeding raw materials.

    One persistent industry problem involves supply chain delays leading to material degradation. The hydroxyethoxy group in our molecule absorbs water from the air, sometimes speeding up spoilage if stored improperly. Years of handling such issues have led us to double-seal containers, implement short-path logistics with trusted carriers, and educate downstream handlers in best practices for minimizing exposure. We believe every extra hour spent explaining these precautions saves laboratories days of wasted time and product loss.

    Another common issue involves trace metallic contamination picked up from old or corroded processing equipment. We made a conscious decision to invest in high-grade stainless steel reactors and regularly audit all lines for corrosion. At each maintenance interval, our technicians check for residue or discoloration inside vessels. Analytical teams support this hands-on effort with regular ICP-MS testing, confirming that any trace contaminants remain under strict limits. This level of control rarely appears in cheaper, distributor-derived material, where manufacturers often hide behind the confusion of the supply chain.

    Supporting Innovation Through Direct Engagement

    Companies using 3-(2-Hydroxyethoxy)Benzaldehyde for cutting-edge work in pharmaceuticals or high-value coatings rarely need more paperwork—they need trusted access to real technical support. As a manufacturer, we keep open lines with our customers, regularly supporting scale-up, providing extra analytical data, or helping interpret spectroscopic results. More than one pharmaceutical client has called late at night, confronting unexpected peaks on an HPLC trace. Our laboratory staff, the same people who monitor daily production, step in and talk through possible impurities, offering not just standard answers, but personalized guidance on lab procedures or extra purification tweaks.

    Research doesn’t slow for supply chain hiccups. Delays in high-purity chemical supply can derail weeks of planning. Having inventory and flexibility in production scheduling helps, but so does streamlined logistics and customs clearance experience. We manage our export processes directly, preparing documentation and anticipating the regulatory binder updates ahead of each shipment. Whenever changes in destination country rules or import quotas emerge, our staff adjusts quickly. Customers relying on our chemical don’t find themselves stuck waiting for clarification or lost samples in transit.

    Intellectual property protection matters, especially in specialty chemicals. We honor customer confidentiality and have strict internal protocols to secure application details. No formulation recipes, process improvements, or unique uses make their way into marketing materials or third-party databases without direct permission from the customer. This trust, built up over years, enables close technical partnerships leading to better results for both sides.

    Real World Experiences in Quality Control and Feedback Loops

    Running a chemical plant means living with continuous improvement. The sharpest lessons come when something doesn’t work as planned, especially during the ramp-up of a new batch. Each anomaly throws the process team into troubleshooting mode. Real-time pressure readings, chromatographic tracking, and even changes in the way samples handle during weighing tell us what to fix. Over time, we started recording not just standard numbers, but observations from plant floor operators—texture, speed of dissolution, even faint color nuances others might overlook.

    Feedback doesn’t just come from within. Users often act as a second line of QC, sometimes noticing what no engineer or analytical chemist would catch. It’s not always technical; sometimes the way product disperses in a mixing tank or how it handles with a glass rod provides clues. We stay in close touch, openly soliciting feedback and leaving no issue unaddressed. Even if a batch meets specs by instrument, if it fails in the field, we adjust. Frequent post-sale surveys and site visits help us observe products as they integrate with customer equipment and routines, letting us spot opportunities for incremental tweaks that support smoother operations.

    For large volume customers, challenges like container contamination or shipping residue occasionally pop up. We invested in sealed, food-grade inner linings and regular testing of every seal and gasket. Routine checks may seem excessive, but prevent expensive recalls and reduce downtime. Reputation doesn’t rest on annual audits but on how quickly and completely we address even minor complaints.

    Shifting Industry Demands: Navigating Evolving Regulatory Expectations

    Every year brings tighter rules around trace contaminants, environmental discharge, and worker exposure to chemicals. 3-(2-Hydroxyethoxy)Benzaldehyde sits in that gray zone, used in products that span regulated drugs, fragrances, and specialty polymers. That intersection means we constantly track new requirements from REACH, the US EPA, and similar agencies abroad. We take regulatory shifts seriously, proactively evaluating raw materials and process aids for suspect lists or blacklist chemicals. When new reporting thresholds or labeling requirements appear, our compliance group communicates with customers, offers full transparency, and adjusts documentation immediately.

    Being a direct manufacturer, we handle documentation at its source. Every certificate of analysis, SDS, and impurity profile is generated in-house and tailored to actual production data. We don’t cut corners by recycling generic spec sheets. When clients need customized documentation, for example for clinical submissions or audits, our technical team compiles the needed details, cross-references data, and delivers support. Those buying through indirect channels rarely enjoy this kind of one-to-one service, an advantage our customers often cite in post-purchase surveys.

    Environmental sustainability continues to grow as a priority for our clients, and by extension, for our production team. Our process engineers constantly search out opportunities to reduce solvent and energy usage, capture and recycle elevated-value waste, and explore alternative raw material providers that manage their own environmental impact. We monitor water effluent and air streams on every batch, closing small leaks before they become environmental or regulatory liabilities. This meant early adoption of vapor mitigation systems, waste exchange partnerships, and energy recovery from heat streams in our reactors.

    Practical Solutions and Plant-Level Innovation

    Finding new ways to lower costs, boost consistency, and respond quickly lies at the heart of being an in-house manufacturer. Our continuous improvement team includes staff from every department, pooling operator experience with lab analytics and real-world logistics know-how. Improvements rarely stem from top-down management decrees alone; they percolate up through daily observations—subtle shifts in product texture, ease of blending, or handling improvements that emerge only after years on the plant floor.

    One example: packaging upgrades resulted from feedback that product caked in the corners of old-style drums. Operations and logistics pulled together, ran trials with different linings and anti-static coatings, and eventually found a film that prevents both moisture transfer and static clumping. Simple, plant-driven changes led to fewer call-backs and less product waste, helping customers get true delivered amounts every single time.

    Another change involved switching to closed-loop filtration, tackling particulate carryover that sporadically surfaced in early product lots. Data tracking, side-by-side comparative runs, and feedback from users working with fine filtration systems led to this upgrade. Since adoption, contamination complaints dropped off dramatically, and user throughput rose. This level of plant engagement—tied directly to customer needs—stands as a main difference between manufacturing in-house and reselling stock.

    Customer Relationships as an Engine for Long-Term Quality

    Sustaining a strong customer base for a complex intermediate like 3-(2-Hydroxyethoxy)Benzaldehyde means more than offering technical compliance and routine specs. Our team engages beyond the point of sale, acting as partners in application development and technical troubleshooting. No two users face the exact same workflow; experience with polymers, drugs, and flavors brings out new questions all the time. Our approach involves listening carefully, adapting processes when recurring issues surface, and returning extra technical clarity when ambiguity threatens project timelines.

    Repeat users tell us that access to both people and product data lowers risk. By encouraging direct contact between production engineers and user chemists, misunderstandings that often plague specialty chemicals give way to productive, trust-based relationships. Whenever a lab or plant needs custom packing, adjusted purity specs, or nonstandard analysis, we work jointly toward the solution instead of hiding behind bureaucracy or third-party reps. In the end, sustained quality comes from a team on both sides striving to improve, one batch at a time.

    Looking Ahead: Evolving Alongside Our Customers’ Needs

    Our work with 3-(2-Hydroxyethoxy)Benzaldehyde constantly evolves. Every regulatory update, market shift, and customer success feeds into our production choices. The know-how built on years of trial, error, and learning by doing shapes every drum and every outgoing shipment. Whether tackling sudden supply chain disruptions, addressing obscure impurity challenges, or working with early-stage researchers racing new products to market, our job remains the same: manufacture with integrity and provide responsive, honest support. Our promise stems not from abstract mission statements but thousands of hours on the plant floor doing the work, learning from every user and every batch that passes through our facility.