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3-(1-Naphthyl)Acrylic Acid

    • Product Name 3-(1-Naphthyl)Acrylic Acid
    • Alias α-Naphthylacrylic acid
    • Einecs 207-477-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    647604

    Productname 3-(1-Naphthyl)Acrylic Acid
    Casnumber 40357-82-8
    Molecularformula C13H10O2
    Molecularweight 198.22
    Appearance White to light yellow crystalline powder
    Meltingpoint 152-155°C
    Solubility Slightly soluble in water, soluble in organic solvents
    Density 1.24 g/cm³ (approximate)
    Purity Typically ≥98%
    Smiles C1=CC=C2C(=C1)C=CC=C2C=CC(=O)O
    Inchi InChI=1S/C13H10O2/c14-13(15)8-7-11-6-5-9-3-1-2-4-10(9)12(11)13/h1-8H,(H,14,15)
    Synonyms β-(1-Naphthyl)acrylic acid
    Storageconditions Store at room temperature, protected from light and moisture

    As an accredited 3-(1-Naphthyl)Acrylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 3-(1-Naphthyl)Acrylic Acid, 25g: Supplied in an amber glass bottle with a secure screw cap and detailed hazard labeling.
    Shipping 3-(1-Naphthyl)Acrylic Acid is shipped in tightly sealed containers, compliant with chemical safety regulations. Packaging ensures protection against moisture, light, and physical damage. Transport follows hazardous materials guidelines, with proper labeling and documentation. Store at controlled room temperature, avoiding exposure to incompatible substances during shipping to maintain chemical integrity and user safety.
    Storage Store 3-(1-Naphthyl)acrylic acid in a cool, dry, and well-ventilated area away from direct sunlight and incompatible substances such as strong oxidizing agents. Keep the container tightly closed and clearly labeled. Avoid exposure to moisture and sources of ignition. Store at room temperature and ensure good laboratory practices when handling or storing this chemical.
    Application of 3-(1-Naphthyl)Acrylic Acid

    Applications of 3-(1-Naphthyl)Acrylic Acid in Industrial Manufacturing

    Our chemical manufacturing facility supplies 3-(1-Naphthyl)acrylic acid directly to industrial customers with precise batch traceability and technical support. This specialty intermediate is widely applied in advanced synthesis for pharmaceuticals, specialty dyes, and fine chemicals. The following sectors represent core application pathways of this material based on established downstream integration.

    1. Synthesis of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intermediates

    Large pharmaceutical manufacturers incorporate this raw material during the synthesis of naphthyl-based NSAID intermediates through Heck-type cross-coupling and further derivatization. This aromatic acrylic acid structure fits as a critical building block in selective modifications for APIs, including molecular scaffolds required for next-generation anti-inflammatory agents.

    Industry compliance standards

    • Active Pharmaceutical Ingredient (API) GMP compliance (ICH Q7, FDA 21 CFR Part 211)
    • European Pharmacopoeia Monographs for intermediates (where applicable)
    • Environmental and occupational safety (OSHA Hazard Communication Standard)
    • REACH registration for use in pharmaceutical synthesis

    Typical usage ratio

    • Usage at 0.12–0.35 molar equivalents relative to the final API batch size, adjusted based on target substitution patterns and process yield optimization.

    Downstream process integration

    • Charged during Stage II or III of multi-step batch synthesis, after initial aryl halide formation, followed by cross-coupling and hydrogenation steps.

    Final product types

    • Non-steroidal anti-inflammatory drug intermediates
    • Research-grade naphthalene derivatives for clinical trial material
    • Bulk pharmaceutical chemicals for custom synthesis contracts
    • Precursor solutions for R&D in medical chemistry innovation pipelines

    2. Advanced Organic Pigment Production

    Specialty pigment manufacturers use this aromatic acrylic acid as a coupling agent for the synthesis of high-performance naphthyl-based pigments. The reactive vinyl group enables precise molecular design and fine-tuning of hue and dispersibility, meeting tight optical and stability specifications for plastics, inks, and coatings.

    Industry compliance standards

    • EU REACH (EC No 1907/2006) for pigment feedstock
    • ISO 9001:2015 (Quality Management for pigment processing)
    • ASTM D3723 (Pigment performance testing in plastics)
    • Global Harmonized System (GHS) labeling for chemical pigments

    Typical usage ratio

    • Feedstock incorporation at 3%–14% by mass of pigment raw mix; adjusted lower for high-tinting strength grades, up to 17% in multi-conjugate coupling formulations.

    Downstream process integration

    • Blended during pigment coupling reaction prior to precipitation; followed by filtration, drying, and micronization according to application particle size requirements.

    Final product types

    • High-performance naphthalene pigments for plastics and masterbatches
    • Organic pigment dispersions for inks and digital printing
    • Specialty colorants for automotive and industrial coatings
    • Granulated colored concentrates for thermoplastic extrusion

    3. UV-Absorber and Photostabilizer Intermediate Synthesis

    Producers of ultraviolet absorbers and photostabilizers for polymer applications deploy this substrate in the synthesis of naphthyl acrylic derivatives. The molecule’s conjugated double bond system delivers efficient UV energy absorption, serving as a precursor to advanced light stabilizing additives for films, fibers, and plastic surfaces.

    Industry compliance standards

    • RoHS Directive (EU 2011/65/EU) for additives in electrical/electronic equipment
    • FDA 21 CFR 177.1520 (for photostabilizer use in food-contact plastics, if applicable)
    • ISO 4892-2 (Accelerated weathering test standards for plastics)
    • REACH and EU Ecolabel criteria for polymer additives

    Typical usage ratio

    • Synthesis input at 5–12% by weight for typical batch scales; adjust to 2–6% for low-density applications, or higher ratios for films requiring maximum UV block performance.

    Downstream process integration

    • Introduced during key step of functional group elaboration after initial amide protection, yielding precursor compounds that are further functionalized and purified before blending into polymer additive formulations.

    Final product types

    • UV-absorber intermediates for polyolefin and polyurethane industries
    • Photostabilizers for synthetic fibers and engineering plastics
    • Concentrates for masterbatch production targeting film and sheet extrusion
    • UV-protective coatings for automotive, construction, and packaging films

    4. Synthesis of Functional Monomers for Specialty Polymers

    Producers of specialty polymers utilize the material as a pre-functionalized monomer for advanced acrylic or vinyl copolymer synthesis. Its aromatic and unsaturated structure enables fine chemical tuning of chain properties, adhesive quality, and thermal stability, supporting innovation in high-end adhesives, resins, and engineered plastics.

    Industry compliance standards

    • ISO 14001:2015 (Environmental management in polymer manufacturing)
    • ASTM D4000 (Standard classification for rubber and plastic materials)
    • EU Directive on Packaging and Packaging Waste (94/62/EC, when used in packaging polymers)
    • Compliance with customer-specific quality control and monomer residual limits

    Typical usage ratio

    • Copolymerization loading of 1–6% by mol, tailored for specific mechanical property targets; can be reduced in combination with other functionalized monomers or increased in gelling resin applications.

    Downstream process integration

    • Added to pre-polymerization reactor feed under nitrogen or argon atmosphere at controlled temperature, followed by chain extension or cross-linking with vinyl or methacrylate co-monomers, and subsequent purification to targeted MW and polydispersity.

    Final product types

    • Functional acrylic copolymers for high-performance adhesives
    • Modified engineering resins for electronics and automotive sectors
    • Reactive monomer systems for advanced composites
    • Novel polymer matrices for specialty coatings and encapsulants
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    Certification & Compliance
    More Introduction

    Introducing 3-(1-Naphthyl)Acrylic Acid: Perspective from the Manufacturer

    What 3-(1-Naphthyl)Acrylic Acid Means to Our Facility

    3-(1-Naphthyl)Acrylic Acid, or MNA, remains one of those compounds that turn batches from routine to remarkable on a production floor. We're not just running reactors or filling drums; we're working with molecular structure and chemical behavior each day. As a manufacturer, we recognize how this acid brings real value to applications stretching from chemical synthesis to complex intermediate work in pharmaceutical and agrochemical fields. We shape our processes around its quirks and advantages.

    Model: 3-(1-Naphthyl)Acrylic Acid, C13H10O2 Purity: Up to 99% GC confirmed Physical Form: White to off-white crystalline powder Molecular Weight: 198.22 CAS: 4038-16-2 Melting Point: 203–206°C

    Focus on Quality and Consistency

    On our shop floor, every barrel of 3-(1-Naphthyl)Acrylic Acid carries the hours and expertise of personnel who know that superficial uniformity misses the point. What matters is the reproducibility of reactions, batch clarity, and how our acid behaves in the customer’s hands. Lab reports only give half the story. Visual inspection, solubility checks, and repeated melting point analysis help us confirm that our batches avoid the pesky side-products and isomeric drift that can wreck downstream syntheses.

    The biggest concern has always been self-polymerization or caking under variable climate storage. We run humidification trials, and staff input helps tweak our process: slower cooling during crystallization, longer filtration to reduce residual solvent trapped in the grains. These decisions have flattened out the “bad batch” warnings we once received from buyers processing at larger scales or under continuous conditions.

    How Chemists Actually Use It

    Pure 3-(1-Naphthyl)Acrylic Acid carries its weight in certain C–C coupling reactions, especially in laboratories synthesizing active intermediates for drugs, specialty dyes, and some plant-regulating chemicals. Most end-users tell us about directing functional groups to the naphthyl core or using the acid as a building block to prepare extended conjugated systems (π-systems). The acrylic acid side chain opens selective hydrogenation and metathesis doors not available in many similar carboxylic acids.

    Looking at the purchase orders, a good chunk of our regulars—a mix of R&D chemists, API (active pharmaceutical ingredient) developers, and some polymer scientists—prefer our batches because they don’t fight through purification headaches after delivery. We spent years reducing trace naphthol, naphthalene, or unconjugated byproducts, which makes a difference when applications need high signal-to-noise ratios in scientific analysis or tight regulatory specifications.

    What Distinguishes Our Manufacturing Approach

    On a practical level, our team manages unpredictable temperatures, odd feedstock lot behaviors, and more exotic analytics than show up in a typical QA file cabinet. We catch issues that might escape less-involved hands, like impurity profiles shifting from a catalyst change or changes in naphthol input quality. These details matter in a business where the end result depends on the reliability of the starting material.

    In terms of the broader chemical supply chain, some participants buy bulk, repackage, and ship without direct feedback from end-users. As chemical manufacturers, our people handle each step, so we pick up on changing analytical trends, developing purity issues, and the subtleties from one batch of raw material to the next. The number of times our crew discovered off-odors, nonstandard crystal morphology, or slow filtration rates serves as a reminder that knowledge gained on the shop floor trumps what’s found in sales brochures.

    Why 3-(1-Naphthyl)Acrylic Acid Differs from Close Alternatives

    Structurally, 3-(1-Naphthyl)Acrylic Acid differs from simple cinnamic acids or substituted benzenes by way of its bulky naphthyl component. This extra aromatic ring changes electronic properties, solubility profiles, and reactivity, so protocols meant for cinnamic acid don’t always deliver ideal results. In practice, chemists tell us that the naphthyl ring can lengthen stability in extended π-systems, making it a favored intermediate for certain dyes and advanced functional materials. The acid group position (β,β'-configuration on the acrylic chain) alters the way amino group substitution or halogenation proceeds during later steps.

    From a handling perspective, it packs down differently, absorbs moisture at a different rate, and crystallizes more slowly than other carboxylic acids in its weight class. We spend a lot of time teaching new operators why visual cues—luminescence under UV light, subtle odor traces, or even stickiness—signal a lot about product health.

    From Batch Development to Bulk Production

    Scaling production of 3-(1-Naphthyl)Acrylic Acid involves a balancing act between classic organic synthesis and rigorous process control. The route begins with naphthyl aldehyde condensation followed by an aldol reaction, or sometimes through Wittig pathways depending on market pressure and raw material availability. Our engineers decided against continuous-flow for this compound, favoring batch reactors that offer more oversight per run. Each vessel includes temperature and pressure probes, as well as rapid-sampling ports for real-time purity checks.

    Worker experience ranks above textbook-perfect reaction monitoring because the smallest deviation—the wrong color during reflux, off-gassing too soon, sticky crystals after cooling—almost always means a future problem. We’ve seen how excess humidity or a delayed filtration can make solidification inconsistent, which then snowballs into process delays or double-work during milling. Feedback loops among operators, chemists, and quality control create this living knowledge pool that balances reaction tempos, filtration speeds, and drying cycles.

    We’ve encountered occasional batch loss from entering the neutralization too quickly, causing sudden temperature spikes or unexpected precipitation, which then compacts too densely to achieve the right particle size. By slowing the process and training staff on visual and tactile cues, we’ve reduced these events to rare occurrences.

    Supplying for Real-World Demands

    Industrial clients want reliable delivery windows, but more than that, they demand consistent material response in their own pilot or production runs. Our most vocal buyers give us both praise and constructive headaches: joint troubleshooting on scale-ups, after-sales fielding of unusual analytical results, or requests for re-crystallization to support analytical clarity (NMR, HPLC, or mass spec).

    We ship the acid in lined drums or sealed bags (depending on order size and air sensitivity), using only materials we’ve tested for compatibility with both the compound and regional climate challenges. International shipments get extra packing, moisture scavengers, and shipment-by-shipment feedback loops. Dozens of supply partners relay data on shipment integrity; our team logs rate of caking, color changes, and customer-reported impurity levels upon receipt, helping us continuously improve logistics.

    We field requests for purity upgrades, custom particle sizing, or special blends. Each modification means more time in the lab adjusting crystallization rates or blending, but this responsiveness forges longer-term customer relationships. The production floor doesn’t see itself as churning out undifferentiated chemical “widgets”; for us, the repeat orders and technical calls help us tune the process far beyond what a standard chemical distributor could accomplish.

    Downstream Uses and Industry Impact

    Routine feedback from API developers and agrochemical formulators gives us insight into the compound’s journey far past our loading dock. In the pharmaceutical sector, 3-(1-Naphthyl)Acrylic Acid helps in forming intermediates, specifically where aromatic stacking or precise carboxyl group placement proves critical in synthesizing new molecular entities. Dyes and pigment makers also chase its naphthyl backbone, spinning it into extended conjugated networks that achieve richer, more stable hues.

    Some polymer and material science labs turn to this acid for its dual properties—the electron-rich aromatic system and the reactivity of its acrylic side chain—when designing polymers with unique optoelectronic features. Feedback from this sector helped us tighten up moisture control and crystal size, since downstream applications often rely on suspension polymerization or thin-film creation, where batch-to-batch consistency in solid form can either make or break a test campaign.

    Research centers often run screening programs using our product. Based on their reports, low levels of naphthalene or alternative acrylic acids can cause side reactions that either reduce yield or complicate post-reaction purification, especially for lab-scale organic synthesis. Our fine-tuning of the process responded directly to these field data.

    Process Improvements Through Experience

    Years on the plant floor taught the team that small deviations in input quality, environmental swings, and operator turnover can morph into very real production hiccups. Our managers stress on-the-job mentoring, routine cross-checks between lab and floor staff, and unfiltered feedback during shift handovers.

    We rotate operators through each stage: reaction set-up, crystallization monitoring, dry milling, and bulk packing. This cross-training means fewer missed warning bells. Staff notice: a subtle color shift in the reflux stage (from pale yellow to orange hints at oxidative decomposition), the difference in feel between properly dried crystals and slightly damp clusters, or how slow filtration in winter signals a tweak in vacuum adjustments.

    We also rework our raw material contracts regularly. In real terms, this means not just waiting for analytical certificates from suppliers, but independently testing each incoming drum, sometimes rejecting $10,000 lots if the base naphthol fails QA, regardless of delivery schedules.

    Production schedules often hinge on more than textbook timing. Holidays, power outages, and stormy seasons in our region shape our output. We keep target stock levels well above what forecasts demand, using downtime for system upgrades or preventive maintenance so that spikes in customer needs don’t catch us off guard.

    Feedback Loops and Product Evolution

    Interactions with our buyers shift the way we work, often leading to product and process changes. A feedback call about slow dissolution prompted us to tweak our drying regime, improving wettability in polar solvents. Another incident—a recurring, faint off-odor—inspired us to upgrade our extraction solvents, dropping residual aromatic hydrocarbons to below detectable limits.

    From handling hundreds of export shipments, we’ve learned that customs and regulatory reviews run more smoothly when our documentation is exhaustive. Certificates of analysis get updated to reflect not just purity by GC, but specific tests for volatiles, trace metals, and unusual contaminants that could delay customer R&D efforts.

    Outbound drums feature batch-specific QR codes, linking end-users directly with lot-level data, change notices, and digital batch certifications. This ongoing transparency tightens end-user confidence and opens doors for direct dialogue, speeding up troubleshooting or collaborative product development when needs shift.

    Regulatory Practice and Environmental Safeguards

    No process stands apart from regulation. In our district, waste water compliance and emission standards bring challenges. Our wastewater gets tested for organic load, pH swings, and trace aromatics. Failures cost not just regulatory headaches, but lost community trust. We keep documentation open-access for regulators, inspired by the view that clean processes build a company’s reputation far more than glossy sales promises.

    In production, our acid separation uses closed reactors and vapor scrubbers. Residual solvents are captured and either recycled or professionally disposed. Drying systems rely on filtered air recirculation and HEPA panels instead of just venting to atmosphere. Attention to these controls changed how our workers see chemical manufacturing—a commitment to health and sustainability over short-term savings.

    On rare occasions, small leaks or spills happen. We treat these as teaching moments, retraining staff and upgrading process protocols. Every environmental audit is treated as an opportunity to re-examine workflows and process safety. We’ve tracked measurable reductions in process-related waste, with efficiency gains funneled back into plant modernization and worker training.

    Comparing Against Widely Available Cinnamic Acids

    Market prices for standard cinnamic acids run lower, but that misses the point for scientists and manufacturers who need the performance profile of a naphthyl-based acrylic acid. Subtle reactivity differences—especially in electrophilic addition, photochemical stability, and aromatic stacking—give our acid an edge in several target markets. The naphthyl ring’s added bulk and resonance effects change downstream chemistry, often delivering better yields and fewer byproducts in certain fine chemical syntheses.

    Commercial-scale processors appreciate that the acid group’s location and steric environment block off certain side reactions while opening up others not possible using phenyl analogues. This shift helps form purer, more crystalline salts, fine-tune reaction kinetics, and reach specificity goals unattainable with other building blocks.

    We track our competitors’ batches, noting subtle odor, caking, or crystal patterning differences. Side-by-side customer feedback studies help us benchmark our quality, while routine lab-scale applications keep us tuned into shifts in global market preference.

    The Realities of Manufacturing and Customer Collaboration

    Producing 3-(1-Naphthyl)Acrylic Acid at scale straddles the line between straightforward organic chemistry and a craftsman’s trade. Chemical engineering minimizes risk and waste, but living knowledge—operator experience, cross-shift dialogue, and direct customer input—shapes what leaves the plant in each shipment.

    We partner with select university labs and industrial R&D teams on process optimization, leading to reduced energy use, smaller environmental footprints, and more consistent endpoints. These collaborations often begin with problem-solving at the user’s bench—unexpected side reactions, slow filtration, or odd crystallization—coming back to our plant with ideas that lead to real changes.

    The cycle keeps evolving: production tweaks born out of field complaints, raw material substitutions based on global supply chain shifts, feedback from on-site application trials, and ongoing dialogue with both our procurement and regulatory teams. We understand the stakes here; a small change upstream can echo through someone’s patent, product launch, or even regulatory dossier, so every modification goes through a rigorous review, technical debate, and staged validation.

    Looking Forward

    Manufacturing 3-(1-Naphthyl)Acrylic Acid draws on years of technical, regulatory, and hands-on experience. The journey from raw naphthyls to finished acid touches chemistry, process control, logistics, safety, and open communication. Our plant continues to refine its output, drawing lessons from operator know-how, regulatory shifts, feedback from real-world users, and field data from a worldwide customer base.

    The product’s success depends on this web of expertise. Its differences from alternatives rest not just in numbers on a spec sheet, but in the ways it meets demanding downstream needs and adapts to ever-evolving requirements. We see ourselves not as producers of a simple reagent, but as partners in our customers’ work. The history of 3-(1-Naphthyl)Acrylic Acid at our facility reflects an approach grounded in practical realities, direct user engagement, and ongoing improvement at every stage of production.