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2-(Trifluoromethyl)Benzophenone

    • Product Name 2-(Trifluoromethyl)Benzophenone
    • Einecs 216-012-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    947697

    Chemical Name 2-(Trifluoromethyl)Benzophenone
    Molecular Formula C14H9F3O
    Molecular Weight 250.22
    Cas Number 348-34-7
    Appearance White to off-white crystalline powder
    Melting Point 46-50 °C
    Boiling Point 330-332 °C
    Density 1.295 g/cm³
    Solubility Slightly soluble in water; soluble in organic solvents such as ethanol, ether, and chloroform
    Purity Typically ≥98%
    Smiles FC(F)(F)c1ccccc1C(=O)c2ccccc2
    Refractive Index 1.577 (at 20 °C)
    Synonyms 2-Trifluoromethylbenzophenone; o-(Trifluoromethyl)benzophenone

    As an accredited 2-(Trifluoromethyl)Benzophenone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 25 grams, tightly sealed with a screw cap; features hazard labeling, product name, lot number, and manufacturer details.
    Shipping **Shipping Description:** 2-(Trifluoromethyl)Benzophenone is shipped in tightly sealed containers, protected from moisture and light. The chemical is classified as non-hazardous under standard shipping regulations but should be handled with care. Transport is generally by road or air, complying with local and international chemical transportation guidelines. Proper labeling ensures safe and compliant delivery.
    Storage Store **2-(Trifluoromethyl)benzophenone** in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizing agents. Keep the container tightly closed and protected from light and moisture. Use appropriate, clearly labeled chemical storage containers. Ensure proper ventilation to prevent vapor accumulation and avoid sources of ignition. Follow all relevant safety and regulatory guidelines for storage.
    Application of 2-(Trifluoromethyl)Benzophenone

    Applications of 2-(Trifluoromethyl)Benzophenone in Industrial Manufacturing

    As a direct producer of 2-(Trifluoromethyl)Benzophenone, we support a range of high-value industrial sectors—each with stringent technical and regulatory demands. Below you will find the proven, large-scale application fields for this specialty intermediate, with full technical and compliance details reflecting real-world downstream use.

    1. UV-Curable Coatings for Electronics and Optical Devices

    2-(Trifluoromethyl)Benzophenone carries an aromatic ketone structure with high electron-withdrawing capability, making it an efficient Type I photoinitiator in UV-cured coatings—especially for circuit boards, flexible displays, fiber optics, and precision lenses. It enables rapid crosslinking and high weather resistance, while meeting strict emission and stability criteria outlined by the electronics sector.

    Industry compliance standards

    • IEC 61249-2-21:2017 (Halogen-free materials standards in PCBs)
    • REACH Annex XVII, Regulation (EC) No 1907/2006 (chemical restriction compliance)
    • RoHS 3 (EU Directive 2015/863)
    • UL 746C (polymeric material performance)

    Typical usage ratio

    • 0.5–4.0 wt% of total coating formulation, adjusted based on film thickness, lamp intensity, and presence of co-initiators or sensitizers

    Downstream process integration

    • Pre-mixed with resin base and pigment binder before thin-film casting; UV exposure occurs immediately post-application on substrates such as PET or glass

    Final product types

    • Protective solder masks for printed circuit boards (PCBs)
    • Scratch-resistant coatings for smartphone camera lenses
    • Encapsulation layers for flexible OLED displays
    • UV-cured adhesives for fiber optic connectors

    2. Synthetic Intermediate for Pharmaceutical Active Ingredients

    In pharmaceutical synthesis, 2-(Trifluoromethyl)Benzophenone functions as a reactive building block for APIs where the trifluoromethyl group imparts metabolic stability and increased lipophilicity. Its primary use is in multi-step organic reactions that require selective introduction of fluoroaromatic motifs, suitable for advanced intermediates in anti-inflammatory and CNS drug research.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF and Ph. Eur. General Chapters on intermediates and process chemicals
    • FDA 21 CFR Part 211 (cGMP requirements)

    Typical usage ratio

    • Varies from 0.1 to 1.2 molar equivalents depending on target molecule and synthesis step; often serves as a limiting reagent in Grignard or Friedel-Crafts alkylations

    Downstream process integration

    • Charged in early/mid-stage synthesis within dedicated API block reactors under inert gas; undergoes stepwise conversion via reductions, halogenations, or aminations based on synthetic pathway

    Final product types

    • Pharmaceutical intermediates for anti-inflammatory drugs
    • Building blocks for CNS agent development programs
    • Research scale fluorinated analogues for structure-activity screening

    3. Photoinitiator Component in Advanced Inkjet Printing Inks

    The compound’s photoreactive nature and compatibility with acrylate monomers enable its use in UV-initiated inkjet formulations for high-resolution digital printing—particularly on non-absorbent substrates such as metal, glass, and plastics. It helps achieve rapid surface cure, precise dot gain control, and chemical resistance critical to industrial and commercial print systems.

    Industry compliance standards

    • EN 71-3:2021 (Toy safety for printing inks for toys and packaging)
    • Swiss Ordinance on Materials and Articles in Contact with Food (SR 817.023.21, for indirect food packaging prints)
    • EuPIA Exclusion Policy for Printing Inks and Related Products

    Typical usage ratio

    • 1.0–3.5 wt% based on total ink formulation; dosage depends on pigment concentration, print speed, and substrate type

    Downstream process integration

    • Premixed with monomer/oligomer blend before microfiltration; ink is jetted onto substrate, then irradiated by mercury or LED lamps for instant polymerization/fixation

    Final product types

    • Industrial barcodes and QR code labels on bottles and cans
    • Decorative high-durability prints on consumer electronics
    • Functional markings for automotive dashboards

    4. Synthesis Additive for Specialty Polymers

    In the specialty polymer sector, this intermediate acts as a controlled-functional monomer or end-capping agent, enabling introduction of fluorinated aromatic segments that significantly improve polymer resistance to solvents, UV exposure, and hydrolysis. Its role is vital in producing advanced materials for demanding environments such as aerospace wire insulation and high-performance membranes.

    Industry compliance standards

    • ASTM D638 (tensile properties of plastics)
    • UL 94 (flammability ratings for polymeric materials)
    • ISO 9001:2015 (Quality Management Systems in polymer manufacturing)

    Typical usage ratio

    • 0.2–1.0 mol% relative to total monomer content, with adjustment based on desired mechanical and chemical resistance parameters

    Downstream process integration

    • Introduced during prepolymerization with other aromatic or aliphatic monomers; reaction typically performed in a nitrogen-blanketed reactor at 80–120°C, followed by extrusion or solvent casting

    Final product types

    • Fluorinated polyimide films for aerospace wiring
    • Hydrolysis-resistant specialty polyesters for filtration media
    • UV-stable elastomeric membranes used in fuel cell and chemical processing equipment

    5. Photochemical Research and Synthesis Tool

    Advanced research laboratories use this compound as a standard reference for photophysical studies and as a test reagent for evaluating novel photocatalytic processes. Its well-defined absorption spectrum and high triplet yield support predictive modeling and scale-up studies in R&D settings, contributing to innovations in materials chemistry.

    Industry compliance standards

    • ISO/IEC 17025:2017 (lab testing and calibration competence)
    • GLP (Good Laboratory Practice) guidelines for research materials
    • OECD Test Guidelines for Phototoxicity (TG 432)

    Typical usage ratio

    • Concentration ranges from 1–10 mmol/L in laboratory photoreactors or analytical vials; custom dilution possible depending on device optics and detection limits

    Downstream process integration

    • Dissolved in non-reactive solvents for irradiation studies; compound can serve as a positive control or as part of quantum yield determination assays

    Final product types

    • Reference standards for spectrophotometric calibration
    • Photochemical modeling samples used in academic and industrial R&D
    • Validation kits for analytical instrumentation suppliers
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