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2-Phenyl-2-Propanol

    • Product Name 2-Phenyl-2-Propanol
    • Alias Benzhydrol
    • Einecs 202-708-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    945296

    Cas Number 617-94-7
    Molecular Formula C9H12O
    Molar Mass 136.19 g/mol
    Appearance White to off-white crystalline solid
    Boiling Point 211-213 °C
    Melting Point 54-58 °C
    Density 1.016 g/cm³
    Solubility In Water Slightly soluble
    Refractive Index 1.527
    Flash Point 96 °C
    Synonyms Benzhydrol, α,α-Dimethylbenzyl alcohol
    Chemical Structure C6H5C(CH3)2OH
    Iupac Name 2-phenylpropan-2-ol
    Vapor Pressure 0.025 mmHg at 25 °C
    Pubchem Cid 12223

    As an accredited 2-Phenyl-2-Propanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle labeled "2-Phenyl-2-Propanol, 99%." Contains 100 mL. Includes hazard symbols, lot number, and safety instructions.
    Shipping 2-Phenyl-2-Propanol is typically shipped in tightly sealed containers to prevent leakage and contamination. It should be transported according to local, national, and international regulations for organic chemicals. This chemical should be kept in a cool, well-ventilated area away from sources of ignition, oxidizers, and incompatible substances during transit.
    Storage 2-Phenyl-2-propanol should be stored in a cool, dry, well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. Keep the container tightly closed and protected from light. Store at room temperature and avoid excessive heat. Use appropriate chemical storage containers, and ensure spill containment measures are in place. Label all storage containers clearly.
    Application of 2-Phenyl-2-Propanol

    Applications of 2-Phenyl-2-Propanol in Industrial Manufacturing

    2-Phenyl-2-Propanol plays a specialized role across several industrial sectors owing to its unique chemical structure and organoleptic profile. As a direct manufacturer, we supply this material for established downstream applications, supporting both large-scale and specialty production processes that rely on precise formulation and regulatory compliance. Below, we outline the principal manufacturing arenas where this compound is essential and detail how our product integrates into each, covering industry regulations, dosage benchmarks, downstream workflows, and resultant end products.

    1. Fragrance Ingredient Manufacturing

    In fragrance compounding, 2-Phenyl-2-Propanol provides nuanced floral and balsamic notes, supporting mid and heart accords in finished perfumes and personal care products. Leading fragrance houses favor its stability and odor profile during both creative formulation and mass production, where safety, purity, and olfactory integrity are mandated by strict IFRA guidelines and client audits. Its use in formulations is finely adjusted based on target scent, volatility, and compatibility with other aromatic compounds.

    Industry compliance standards

    • IFRA Standards (current Amendment)
    • REACH Regulation (EC) No 1907/2006
    • Cosmetics Regulation (EC) No 1223/2009 (for downstream cosmetic applications)
    • ISO 9235:2013 (Aromatic Natural Raw Materials - for blending compliance)

    Typical usage ratio

    • 0.01–1.5% in concentrate, varying with the intensity of the fragrance base; higher for fine fragrance editions, lower for functional perfumery; dosage set during stability and IFRA compliance testing.

    Downstream process integration

    • Added during the oil phase blending after initial fixatives and prior to final top note adjustments; dissolved with other aromatics before compounding; filtered and QC-tested before dilution to final strength.

    Final product types

    • Fine perfumes (EDP, EDT, parfum concentrates)
    • Personal care fragrances (shampoos, shower gels, creams)
    • Air care and home fragrance solutions (candles, diffusers)

    2. Pharmaceutical Intermediate Production

    Pharmaceutical manufacturers use 2-Phenyl-2-Propanol as a structural intermediate in active pharmaceutical ingredient (API) synthesis, especially where specific chiral or aromatic alcohol frameworks form part of the pharmacophore. It supports controlled Grignard and Friedel–Crafts pathways, where pharmaceutical GMP and impurity profiling are stringently monitored. End users demand transparent documentation for each batch entering their validated medicinal chemistry pipelines.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF Monographs where applicable to the target API
    • 21 CFR Part 211 (cGMP for Finished Pharmaceuticals)
    • European Pharmacopoeia (Ph. Eur.) for intermediate handling if routed into EU-authorized medicines

    Typical usage ratio

    • Varies according to stoichiometry in target API synthesis route; typically 1 to 1.2 molar equivalents relative to the limiting reagent, with excess minimized to reduce downstream purification burdens.

    Downstream process integration

    • Introduced at specific non-aqueous reaction stages; often charged in protected environment with inert gas; subjected to reaction, work-up, then isolation by crystallization or distillation as part of regulated process batch records.

    Final product types

    • Intermediates for antihistamine APIs (e.g., certain alkylamine derivatives)
    • Building blocks for central nervous system drug candidates
    • Chiral auxiliaries employed in production of specialty APIs

    3. Polymer Resin Modifier

    Industrial resin and polymer producers integrate 2-Phenyl-2-Propanol as a modifier to adjust polymer matrix polarity and to improve surface finish or flexibility in engineered plastics and coatings. The aromatic alcohol moiety allows controlled alteration of resin characteristics, supporting enhanced performance in high-spec composites, electronics encapsulants, and specialty adhesives. Here, raw material traceability and compliance to environmental and migration standards are prioritized by QC teams.

    Industry compliance standards

    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances in Electrical Equipment)
    • UL 94 and IEC 60695 (Polymer Flammability and Safety)
    • ISO 9001:2015 Quality Management System (applicable to all certified resin plants)
    • ECHA SVHC (Substances of Very High Concern) List for polymer additives

    Typical usage ratio

    • 0.5–2.0% by weight in polymer matrix; adjustment based on targeted melt viscosity, compatibility with reactive additives, and required mechanical property specification in final product qualification tests.

    Downstream process integration

    • Metered into prepolymer mixture or directly into reaction vessel during melt stage; thoroughly mixed before chain extension and curing; sometimes pre-reacted with co-monomers for copolymer applications.

    Final product types

    • Engineered thermoplastics for electronics housings
    • Specialty coatings and varnishes
    • Industrial adhesives and sealants

    4. Specialty Solvent in Fine Chemical Synthesis

    Producers of fine chemicals adopt 2-Phenyl-2-Propanol as a process solvent and reaction medium, especially where steric and aromatic compatibility can aid solubilization or promote selectivity in arylation, alkylation, or reduction processes. Its physicochemical profile allows strategic use in high-value syntheses demanding low impurity backgrounds and reliable batch-to-batch consistency, with solvent residues managed per sector best practices.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management (for waste handling and emissions)
    • REACH Regulation (EC) No 1907/2006 (substance and mixture handling)
    • Responsible Care® Global Charter (Ethical chemical management in production)
    • EU Solvent Emissions Directive (1999/13/EC)

    Typical usage ratio

    • 10–80% v/v in reaction media according to solubility and selectivity requirements, adjusted by reaction kinetic studies and post-reaction recovery protocols for solvent recapture or exchange.

    Downstream process integration

    • Charged into glass-lined reactors or jacketed vessels as part of solvent blend; kept under controlled temperature and agitation; recovered post-reaction via distillation for multiple cycles depending on process validation.

    Final product types

    • Flavor and fragrance intermediates
    • Agrochemical intermediates
    • Photoinitiators and specialty arylated molecules for electronics
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    Certification & Compliance
    More Introduction

    2-Phenyl-2-Propanol: Factory Perspective on a Trusted Intermediate

    At our plant, 2-Phenyl-2-Propanol stands apart because of the hands-on attention we give at every stage of its production. From sourcing raw materials to final quality checks, we keep one eye on stability, the other on purity. The product carries our model number 125-84-8, an established reference in the catalogue for this compound. We manufacture it with a focus on providing a high standard rather than maximizing output at the expense of consistency.

    Purity and Consistency Rooted in Real Practice

    Many who work closely with chemical intermediates understand that purity isn’t something to take for granted. With 2-Phenyl-2-Propanol, often called benzyl isopropyl carbinol, unchecked impurities ruin downstream syntheses for flavors, fragrances, or pharmaceuticals. Our batches typically reach a purity exceeding 99%, verified on our chromatography systems and confirmed with NMR as part of the release protocol. Customers have told us how tight purity has reduced off-spec waste and simplified process validation. We don’t pull these purity figures out of thin air — they result from reliable rectification, careful control of reaction temperature, and a distillation setup built from years of working with aromatic alcohols. Not every product with a matching CAS number performs the same; minute contamination with water or leftover acids can spell disaster further down the line.

    Physical Qualities and Why They Matter

    Our 2-Phenyl-2-Propanol arrives as a clear, nearly water-white liquid at room temperature. Boiling occurs near 215 degrees Celsius, and its melting point sits close to 54 degrees — higher than simpler phenyl alcohols, giving a measure of thermal stability that many value in process engineering. Assay on raw and finished product runs at 99% or better. Specific gravity falls around 1.02-1.03, so distributors handling it in bulk see little separation or settling, even during seasonal storage shifts.

    Color holds steady over time. This matters to anyone blending intermediates for high-purity fragrances or pharmaceutical actives where even a trace of coloration betrays underlying instability. Our experience shows that tiny changes in post-synthesis workup — whether in washing solvent, distillation rate, or atmospheric exposure — lead to visible shifts. Decades on the line have taught us how to avoid those problems by having final filtration and nitrogen blanketing right up to packaging.

    Key Uses Driven by Industry Experience

    Years of collaboration with formulation and research teams show real-world demand for 2-Phenyl-2-Propanol as a versatile building block. Makers of flavor and fragrance ingredients rely on its aromatic backbone and moderate volatility. It serves as a primary intermediate for compounds such as 2-phenylpropionic acid derivatives and specialty esters. Our technical partners in synthetic chemistry use it to introduce both phenyl and tertiary alcohol motifs, a combination that broadens the synthetic options far beyond structures accessible from benzyl alcohol or isopropyl alcohol alone.

    On the pharmaceutical intermediary side, the compound forms an essential branch point for drug precursors. Its secondary alcohol structure gives predictable reactivity — more robust than the simpler benzyl alcohol, but not prone to the rearrangements often seen with benzhydrol. Feedback from small-molecule process teams usually highlights its compatibility in Grignard-like setups, oxidation, and etherification, reducing the workload required to block or protect multiple functional groups.

    Fields like materials science also turn to this product for specialized monomer and intermediate synthesis, especially where a balance of solubility and thermal resistance is important. Those requirements turn nuanced when scaling up from bench work, and we’ve seen labs hit snags with off-the-shelf alternatives that don’t meet the same specifications we hold ourselves to day in and day out.

    Differences from Other Aromatic Alcohols

    As a manufacturer, we see customers sometimes try to substitute closely related compounds, expecting identical outcomes. To many, all aromatic alcohols seem similar — benzyl alcohol, benzhydrol, and 2-phenyl-2-propanol look alike on paper until the process moves from milligram bench scale to ton production.

    Benzyl alcohol brings higher volatility and much lower melting point, but lacks the tertiary structure that 2-Phenyl-2-Propanol brings. This structural difference shields our product from rapid oxidation and holds back color formation under heat. In the field, this means mixtures using benzyl alcohol sometimes thin out or degrade during long storage, especially in pressured lines or higher-temperature environments. We’ve tested it: reaction endpoints behave differently, as does solubility in polar organic media. Those nuances only become clear through repeated use on the manufacturing floor, not in generic comparative tables.

    Benzhydrol, or diphenylmethanol, weighs in with even greater bulk due to an extra phenyl ring. That gives a higher melting point and severely reduced solubility in typical organic solvents, translating to painful filtration steps and costly, lengthy crystallization that slows production batches. The single phenyl ring of 2-Phenyl-2-Propanol delivers just enough aromatic stabilization with lower viscosity and easier handing in continuous setups — a practical edge that shows up in yield and throughput figures.

    ROSA, phenoxypropanol, and similar ethers all have their niches, especially when lighter odor notes or oxygen resistance are critical. But once functionalization requires direct hydroxyl or secondary carbon targets on the phenyl ring, our product offers reactivity those ethers simply cannot give. Deciding on the right intermediate isn’t just about what’s available; it’s about years of fine-tuned process design behind the scenes, where batches rise and fall on the quirks of a single raw material.

    Industrial and Regulatory Alignment

    Every batch from us undergoes both purity and trace metal analysis using ICP-OES, with results tracked back through our QC logs for at least five years. This comes in handy as customers in regulated sectors — flavors, food additives, and pharmaceutical actives — increasingly demand a full analytical trail. Our staff regularly updates handling protocols and certificates of analysis to match current market and regulatory standards. This avoids the last-minute panic some smaller suppliers face when documentation gaps appear during an audit.

    Handling the product presents few surprises for warehouse and operations teams. No aggressive fumes, low acute toxicity, and minimal vapor pressure make storage and shipment easier compared to low-molecular-weight aliphatic alcohols. In the case of a leak, neat spills limit environmental consequences compared to solvents with higher volatility or aquatic toxicity. Years spent working with national and international shipping handlers give us confidence that best practices stay current. Ships carry the product in standard steel or HDPE drums, each batch traceable by QR-coded label. Our plant lets us tailor formats for bulk orders or smaller R&D-scale packaging, depending on the project.

    We’ve seen a slow but visible tightening of regulatory scrutiny worldwide. Anticipating requirements, our quality team has invested in batch-level lot tracking, periodic validation audits, and in-house stability testing under ICH conditions. This means less downtime for downstream users, less red tape in international shipping, and confidence for end-users facing regulatory agencies and their own QA inspectors.

    Safety, Sustainability, and Future-Proofing Processes

    Production teams know the realities of working with phenolic intermediates. The process emits little to no noxious vapor, and personal protective equipment guidelines remain straightforward — splash goggles, gloves, and local exhaust during open transfers keep our workers safe. Past experience has shown us that older glass equipment could pit or crack under sudden temperature shifts, so we’ve shifted to steel and specialty-coated reactors for both batch and continuous distillation. Fewer leaks, reduced downtime, more product per run.

    We approach energy use and waste minimization as basic shop-floor priorities. Each run gets tracked for solvent recovery — toluene and heptane come back into new cycles within our plant. Water use, too, falls under the same scrutiny. By recycling washing stages and optimizing steam use, we’ve reduced our effluent by 30% over the last six years. Actual implementation took months, and results showed up in lower operating costs and smoother environmental audits, not just nice words on a brochure.

    We’ve had to adapt our approach where procurement teams or brand managers want more than just a low price-per-kilo. Our response is to shift toward better environmental footprints and longer shelf life, using real-life durability studies to back up claims. Not every substitute or rival product can guarantee the same, especially those routed from multiple smaller plants piecing together their supply. Centralized, consistent output gives us the leverage to certify each monthly batch from a single point of control.

    Real User Feedback and Applied Solutions

    Take the example of a European fragrance customer who faced breakdowns and foul odor from a competitor’s material. Their root-cause investigation traced the problem to high residual acetophenone and trace peroxides in the competitor’s intermediate, which triggered instability in the end perfume oil. Switching to our 2-Phenyl-2-Propanol eliminated days of extra filter cycles and late-night equipment scrubbing. Maintenance logs the following quarter documented a near-complete absence of gel fouling, reducing both labor hours and batch reprocessing. This wasn’t a theoretical outcome; it was the result of real-time process tracing and product troubleshooting with their team on a site visit.

    In the pharmaceutical sector, a mid-size API producer had problematic byproduct formation affecting purification downstream. Collaborative adjustment between their process chemists and our technical support — tweaking use rates, storage temperatures, and order-of-addition — optimized their Grignard reaction, improving both throughput and purity on dozens of subsequent runs. They credited the improvement to prompt communication and lot-to-lot consistency that cut R&D investigation time by months. Close dialogue makes this possible, not just a price sheet and a bill of lading.

    Lab teams working on new monomer materials for coatings have repeatedly cited the predictable performance of our 2-Phenyl-2-Propanol in pilot reactors — faster, more even conversion, less fouling than with by-the-ton aromatic blends from spot-market traders. Margin may seem small at the outset, but when downtime and batch loss factor in, their procurement leads make the case with CFOs to stick to a trusted single-source. These hands-on feedback cycles push us to fine-tune both process and after-sales service.

    Hazard Management and End-of-Life Considerations

    A modern chemical operation must face product stewardship with more than lip service. Taking back drum packs for recycling, inspecting for product stability beyond labeled expiration, and supporting customer audits position us as a long-term partner, not just a bulk supplier. Our team regularly checks for off-odor, coloration, or polymer residue as part of after-market surveillance, both to verify shelf life and provide early warnings to clients relying on just-in-time inventory.

    Regulations ask for more than just declarations on paper. We comply with relevant environmental standards, submitting routine waste water analysis and air and vapor emissions reports. We make sure transportation partners handle all shipments in accordance with hazardous goods handling regulations, but hands-on experience gives us a broader picture. Overloading drums, mislabeling, or storing near oxidizers risks more than a simple citation. Our logistics crew has seen real world incidents and learned where to double-check, patch, or shift storage to avoid real harm, guided by practical, factory-floor insight as much as formal paperwork.

    Keeping Pace with Market Needs

    We adapt synthesis protocols and processing schedules according to real industry demand, not just fixed calendar runs. If a downstream project ramps up unexpectedly, our batches adjust flexibly, balancing working capital and tank loads to meet delivery without overstocking. Customers see value in receiving truly fresh-made intermediates, with support documents tracking actual batch production dates and QC release.

    Inside applications labs, a familiar situation plays out: trial reactions or pilot blends either hit spec immediately or miss by a margin, and the prime variable isn’t always obvious. Direct contact with our production and R&D team shortens response time, isolates concerns faster, and sometimes lets a project get back on track in days rather than weeks. That means someone is always available to answer deep technical questions and tweak supply schedules if, for example, a custom viscosity or pre-dilution step is needed.

    We don’t work in a vacuum. From regulatory compliance to analytic upgrades, our operations shift along with requirements from national authorities and blue-chip end users. We actively solicit annual supplier reviews and include real-life audit findings in our internal improvement cycles, using direct customer experience to drive factory floor upgrades, not the other way around.

    Trust Built on Reputation, Not Hype

    Word spreads quickly when a batch runs reliably or sets a new standard. We see the payoff in new requests from buyers who once settled for secondary options where stability or processability mattered less. For those working under pressure to validate, scale, or troubleshoot, cutting corners on core intermediates just isn’t worth the risk. Mastering the nuances of 2-Phenyl-2-Propanol manufacturing means knowing every variable, adjusting quickly, and delivering not just barrels, but a record of safe, reproducible, and well-supported performance at scale.

    For new formulations or existing production lines, our chemical stands out both for consistency and for the accumulated experience behind each shipment. Real-world support, careful process design, and commitment to transparent, high-quality output keep our partners on track, job after job. That goes not just for technical staff building molecules, but for the QC managers who need every box checked and the purchasing teams charged with safeguarding their brand’s reputation. We stand by every batch, because we see the consequence of every deviation long before it hits the customer’s dock.