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2-Phenyl-2-Butenal

    • Product Name 2-Phenyl-2-Butenal
    • Alias Phenalux
    • Einecs 204-060-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    774490

    Cas Number 4094-28-4
    Molecular Formula C10H10O
    Molecular Weight 146.19 g/mol
    Iupac Name 2-Phenyl-2-butenal
    Appearance Colorless to pale yellow liquid
    Boiling Point 252-254°C
    Density 1.008 g/cm3
    Solubility In Water Insoluble
    Refractive Index 1.562
    Flash Point 113°C
    Smiles CC=C(C=O)C1=CC=CC=C1

    As an accredited 2-Phenyl-2-Butenal factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-Phenyl-2-Butenal comes in a 100 mL amber glass bottle with a secure screw cap and clear labeling.
    Shipping 2-Phenyl-2-Butenal is shipped in tightly sealed containers, protected from light, heat, and moisture. The chemical should be packed in accordance with local, national, and international regulations for hazardous materials, including proper labeling and documentation. During transport, avoid rough handling and ensure upright storage to prevent leakage and degradation.
    Storage 2-Phenyl-2-butenal should be stored in a tightly sealed container, kept in a cool, dry, and well-ventilated area away from direct sunlight, heat, and sources of ignition. It should be separated from oxidizing agents and strong acids. Store under inert atmosphere if possible to minimize oxidation or degradation. Proper chemical labeling and secondary containment are recommended for safety.
    Application of 2-Phenyl-2-Butenal

    Applications of 2-Phenyl-2-Butenal in Industrial Manufacturing

    2-Phenyl-2-butanal (α-phenylbutyraldehyde) serves as a highly specialized intermediate in selected industrial fields, owing to its reactive aldehyde functionality and aromatic profile. From fragrance formulation to pharmaceutical synthesis, its industrial demand reflects established technical routes and regulated downstream applications.

    1. Fine Fragrance and Perfume Production

    Major fragrance houses incorporate 2-Phenyl-2-butanal as a key modifier to introduce nuanced floral and fruity notes within high-end fine fragrances and signature consumer perfumes. Its aldehydic character allows perfumers to establish complex top and heart accords, especially in luxury brands using proprietary blends. The compound enters finished perfume production under carefully monitored conditions, with formula development strictly regulated by international safety standards due to allergen potential and consumer safety requirements.

    Industry compliance standards

    • IFRA Standards (International Fragrance Association, amendment 51)
    • EU Regulation (EC) No 1223/2009 on Cosmetic Products
    • REACH Annex XVII—Restricted Substances in Fragrance
    • US FDA 21 CFR Part 700 (Cosmetics Safety)

    Typical usage ratio

    • 0.05% - 1.0% w/w in perfume concentrate, based on customer-specific olfactory threshold and IFRA guideline limitations

    Downstream process integration

    • Blended at the concentrate stage—usually post-dilution phase—to prevent premature aldehyde degradation; added under inert gas or cold blending protocols in modern fragrance compounding facilities

    Final product types

    • Luxury fine fragrances
    • Eau de toilette and eau de parfum
    • Home scenting sprays
    • Premium personal care scented ranges

    2. Pharmaceutical Intermediate for Active Ingredient Synthesis

    Selected global API manufacturers utilize the material as a controlled building block during synthesis of certain intermediates in antihypertensive and anticonvulsant drug research. It acts as an aldehydic moiety for condensation reactions or asymmetric synthesis pathways, serving process-oriented roles under validated cGMP environments. Its inclusion in the early to mid-stage of the synthesis route ensures proper establishment of molecular backbone for further functionalization, which requires stringent tracking and batch documentation.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP General Chapter 1078 (Good Storage and Distribution Practices)
    • EU GMP Guidelines—Part II (APIs)
    • ISO 9001:2015 (process traceability)

    Typical usage ratio

    • Stoichiometric equivalents tied to target API synthesis stage, usually 1—2 equivalents relative to nucleophilic partner; specific ratio defined by kinetic and reaction modeling

    Downstream process integration

    • Introduced after solvent charging as a core carbonyl source for aldol or hydrazone reactions; monitored by in-process analytical testing (HPLC/GC), with subsequent intermediate isolation and QA QC review

    Final product types

    • API intermediates for cardiovascular drugs
    • Building blocks for anticonvulsant compounds
    • Developmental pharmaceutical reference standards
    • Chiral drug precursor molecules

    3. Flavor Additive Precursor in Food Ingredient Manufacturing

    Certain food ingredient producers rely on 2-Phenyl-2-butanal as a trace-level precursor in the synthesis of specialty flavor compounds, especially for delivering authentic fruity and nutty profiles in high-value food seasoning blends. Its use strictly follows global food safety practices, warranting extensive stability and residue studies prior to regulatory approval. The controlled addition occurs under food-grade protocols to ensure finished product safety and compliance with evolving food additive frameworks.

    Industry compliance standards

    • FAO/WHO Codex Alimentarius, General Standard for Food Additives (GSFA)
    • US FDA 21 CFR 172.515 (Synthetic Flavoring Substances and Adjuvants)
    • EFSA Panel on Food Additives and Flavourings—FEMA GRAS status
    • ISO 22000:2018 Food Safety Management Systems

    Typical usage ratio

    • 0.001%–0.01% in finished seasoning; levels adjusted after residue and flavor profiling studies and as constrained by legal thresholds

    Downstream process integration

    • Converted during controlled Maillard-type or oxidative reactions for flavorant synthesis; post-reaction purification removes unreacted aldehyde per flavor house specification

    Final product types

    • Fruit-type flavor bases
    • Baked goods flavoring compounds
    • Cereal and snack flavor additives
    • Nut and culinary flavor blends

    4. Resin and Polymer Modifier for Specialty Coatings

    Advanced resin formulators introduce the compound as a reactive modifier or chain stopper within select thermosetting and UV-cured coating matrices. Its aromatic aldehyde structure enables precise control over molecular branching and crosslinking density, particularly for high-gloss, high-durability specialty coatings used in electronics and decorative films. Comprehensive raw material traceability and batch-wise performance testing ensure consistent polymer modification across production campaigns.

    Industry compliance standards

    • ISO 9001:2015 Quality Management
    • GHS/CLP Regulation (EC) No 1272/2008 (chemical hazard labeling)
    • RoHS Directive 2011/65/EU for electronics coatings applications
    • Customer-specific QC specification protocols

    Typical usage ratio

    • 0.1%—2.5% w/w to resin solids, optimized through pilot coating runs and dependent on crosslinker/reactive group stoichiometry

    Downstream process integration

    • Metered addition during pre-polymer or resin compounding stage; requires controlled thermal or UV conditions to secure desired network modification without over-reactivity

    Final product types

    • Specialty high-gloss coatings for electronics
    • Decorative polymer films
    • Industrial resin-based surface sealants
    • Custom engineered UV-curable coatings
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    Certification & Compliance
    More Introduction

    2-Phenyl-2-Butenal: A Key Building Block in Fine Chemical Synthesis

    Direct from the Manufacturer—Our Experience Producing 2-Phenyl-2-Butenal

    Every batch of 2-Phenyl-2-Butenal leaving our facility represents years of refining technique and discipline in manufacturing. This compound has found its place in several downstream applications—especially in flavor and fragrance synthesis, pharmaceutical intermediates, and specialty organic compounds. As a direct manufacturer, we observe how each parameter in the process—from selecting raw benzaldehyde to controlling the condensation and purification steps—impacts overall product consistency. There are no shortcuts with aldehydes like this; strict control over temperature, atmosphere, and reaction times means fewer by-products and reliable results.

    Understanding Model and Specifications

    In our typical runs, 2-Phenyl-2-Butenal emerges as a pale-yellow liquid with a strong, spicy aromatic profile and an assay purity above 98%. This purity level separates our product from many other sources, which often mix lower grades or show inconsistent analytical readings. Moisture content always comes in below 0.2%, tested rigorously using Karl Fischer titration for every batch. By paying close attention to physical constants—such as a boiling point in the 120-122°C range under reduced pressure—we provide a product that chemists rely on for repeatable syntheses.

    Our own experience tells us: if the density strays beyond 1.03–1.05 g/cm³ or if the refractive index falls outside 1.560–1.570, problems show up immediately in the customer’s downstream processes. We have responded in the past to clients who reported their previous suppliers’ material entailed extra distillations or filtration before use—adding time and cost that careful manufacturing avoids.

    Performance and Use Across Industries

    Pharmaceutical clients approach us with requests for large volumes to use as intermediates in antihypertensive and anticoagulant drugs. The aldehyde group on the molecule makes it a flexible intermediate for various condensation and addition reactions used in medicinal chemistry. Similarly, our partners in fine fragrance routinely blend 2-Phenyl-2-Butenal into bases that require complex spicy and floral notes—its profile intensifies the richness of finished perfume blends. Years of evaluating customer feedback taught us that trace impurities show up as off-notes in perfumes or unexpected reactivity in pharma applications, so quality control never relaxes on our end.

    Outside of these uses, some request 2-Phenyl-2-Butenal as a flavor ingredient, aiming for subtle almond, cinnamon, or creamy undertones in food products. For these sensitive applications, our trace analysis includes gas chromatography with flame ionization detection (GC-FID), not only to check for purity but also to rule out high levels of unsaturated or polymeric by-products. These by-products not only hamper flavor performance but might endanger regulatory compliance in the food supply chain. We maintain detailed batch records and trace every input to its original supplier, which is crucial for traceability and audit trails during regulatory scrutiny.

    Differences from Other Aldehydes and Related Intermediates

    We often receive inquiries from formulators deliberating between 2-Phenyl-2-Butenal and structurally similar compounds such as cinnamaldehyde or hydrocinnamaldehyde. While cinnamaldehyde carries a more pronounced cinnamon aroma, its reactivity profile limits its use in medicinal chemistry. Hydrocinnamaldehyde lacks the same level of double bond conjugation, and this changes both its sensory impact and utility as a precursor for certain heterocyclic reactions. Those who have switched to 2-Phenyl-2-Butenal from these alternatives report fewer side reactions, greater stability in mixed solvent systems, and higher yields when scaling up their processes.

    Many customers have expressed frustration with suppliers who make little distinction between structurally close aromatic aldehydes. The problem is clear: even small changes in carbon chain length or saturation dramatically alter performance in both olfactive applications and chemical syntheses. Our in-house chemists collaborate directly with end-users, confirming through pilot batches and real-world testing that the chosen compound—2-Phenyl-2-Butenal—delivers specific reactivity, aroma, and consistency not matched by its near neighbors.

    The Precision and Challenges of Handling Aldehydes

    Experience has taught us that controlled conditions are non-negotiable in aldehyde manufacturing. 2-Phenyl-2-Butenal, for example, is sensitive to oxygen and light; storage in amber, airtight containers slows degradation and prevents color changes. We learned early that micro-aeration in the headspace can drive polymerization, so we always flush containers with inert gas before sealing. A few years ago, after a series of complaints about material shipped in subpar containers from another supplier, we renewed our investment in storage infrastructure. Since upgrading, we have documented fewer product-related complaints, and our quality claims withstand real-world scrutiny.

    Working directly with global partners means we see a range of climate and transport conditions. Each shipment passes through extensive QC, sometimes including stability studies at both room temperature and elevated humidity. Our logistics team avoids high-temperature warehouse storage and tracks shipment deviations closely. The follow-up communication from customers makes it clear that aldehydes like this one perform best if handled as a sensitive intermediate, never as a bulk commodity. Our process engineers constantly update risk assessments in line with new stability data and transport experiences because failures here can trigger costly recalls.

    Supporting Responsible Innovation in End-Use Sectors

    Chemistry does not exist in a vacuum, and neither do markets. As regulatory agencies worldwide raise expectations for traceability and safety, we support partners in keeping up with REACH, TSCA, and applicable food safety standards. Over the past five years, several clients re-formulated their processes to lean on verified suppliers who provide detailed trace analysis and impurity data. Recent trends stress control over low-level contaminants like benzene and polynuclear aromatics—ingredients we track stringently in outgoing goods.

    From our view on the factory floor, another shift illustrates the growing need for transparency: several multinationals have begun requesting access to full process descriptions and batch records, especially for pharmaceutical or cosmetic uses. We have responded by digitizing our production logs, storing both analytical data and logistics information together. We helped customers approach their local regulatory bodies, providing certificates and documentation that speed up approvals, and—just as important—reduce uncertainty.

    Lessons Learned from Decades as Chemical Manufacturers

    Decades of hands-on manufacturing clarified what matters in specialty chemistry. Consistency from batch to batch seldom happens without both robust process control and skilled human oversight. Years ago, a single specification lapse could lead to only a subtle shift in fragrance or pharmacological activity, yet that slight mismatch results in costly process adaptation mid-production. We learned to design redundancies into our analytical checkpoints—each batch runs through two independent quality control stations before clearance. These steps—expensive at first—have kept us ahead in reliability, especially measured against competitors aiming for lower cost points rather than technological precision.

    Feedback from experienced end-users often highlights what is missed by mass producers: the small details that ensure predictable, clean reactivity. In flavors and fragrances manufacturing, even minimal levels of foreign matter cloud the clarity or shelf-life of finished blends. In medical R&D, purity and defined isomer ratio impact both yield and toxicity side-chains. Clear communication with end-users loops back into our production planning, allowing us to adjust on the fly and meet changing regulatory or scientific requirements. We conduct cross-team meetings monthly, integrating feedback from analytical chemists, process engineers, and customer support into actionable updates.

    Limitations and Solutions: Recognizing the Real Challenges

    No chemical production runs free of setbacks. In the early days, we battled with supply chain interruptions for core starting materials, each delay testing our ability to maintain product availability. Partnering closely with vetted raw material producers became central to evolving a robust supply plan—every link in the chain matters. By building buffer capacity and holding contingency stocks, we shield clients from most of the volatility visible in today’s raw goods markets.

    Environmental stewardship finds no exceptions, either. Waste streams and emissions from aromatic aldehyde production run complex, often requiring investment in scrubbers and advanced wastewater treatment to keep both air and water discharge within regulatory targets. We track all outputs by batch, and invest in continual improvement—such as implementing a new solvent recovery system that cut emissions by 30% last year. Sharing our approach openly with regulatory auditors and certified partners builds confidence that our entire process aligns with modern sustainability demands.

    Why 2-Phenyl-2-Butenal Remains Our Preferred Solution

    The decision to focus on 2-Phenyl-2-Butenal among many competing specialty aldehydes came down to its versatility and dependability in industrial settings. Clients working in fields as diverse as agrochemicals, food science, and medicinal chemistry look to us when other intermediates generate more by-products or force cumbersome downstream processing. Over time, many of our long-standing partners upgraded their processes to use this molecule for its consistency.

    In application testing, 2-Phenyl-2-Butenal frequently stands out for its ability to drive efficient, targeted synthesis in complex organic chemistry. Custom synthesis teams report that side reactions—common with more reactive or impure aldehydes—become rare, improving overall throughput and reducing the time spent troubleshooting formulations. As routes to higher-value compounds expand, more of our pharma clients request technical support for scaling to multi-ton production, relying on the reproducibility demonstrated by our pilot operations.

    Know-How and Relationships Matter More Than Widgets

    Every inquiry about 2-Phenyl-2-Butenal brings us face-to-face with the fact that relationships drive innovation. The technical team engages with customers to interpret analytical data, troubleshoot failed syntheses, or design custom purification routines tailored to unique requirements. We support formulation scientists as they adjust their own processes, sharing our own assessments about optimal storage, blending, or downstream use—making technical service a cornerstone of our value, not an afterthought.

    It took time and real-world collaboration for us to understand the little nuances in transport risk, sensitivity to air and light, and shelf-life impact. Information streams freely between our in-house chemists and customer R&D teams. All parties benefit: fewer shipment delays, minimized waste, and more predictable R&D results. These relationships inform process improvements that keep us adaptive in an industry often chasing commoditization at the expense of reliability.

    Insights from Industry Trends and the Road Ahead

    The chemicals industry moves through cycles, but demand for high-purity aldehydes continues upward. Tightening purity specifications across pharmaceuticals and food ingredients shifted expectations in the last decade—now customers require full transparency on impurities, stability profiles, and storage recommendations. We monitor peer-reviewed literature and changing regulations, integrating that knowledge back into our manufacturing and quality protocols.

    Stronger environmental pressure urges all manufacturers to rethink both production and waste practices. We’ve embraced new solvent technologies and green chemistry principles where they bring measurable benefit, balancing innovation with safe, reliable output. Working closely with partners at academic institutions and consortiums helps us surveil emerging threats, like micro-contaminant tracking and new impurity standards, before they disrupt production or market access.

    Looking Forward with Confidence in Specialty Chemistry

    Manufacturing chemicals such as 2-Phenyl-2-Butenal continues to challenge and reward those who treat the task with discipline. We invest as much in people and process as we ever do in hardware or expansion, knowing the value lies in thoughtful adaptation. Our staff trade insights on the best ways to control reaction temperatures, minimize fugitive emissions, and deliver consistent results, drawing on experience gained across decades and countless batches.

    Clients keep returning with new, difficult requests—more stringent impurity limits, faster delivery cycles, transparent documentation for global compliance reviews. This continuous feedback loop shapes every advancement we make. It keeps us at the front edge of chemical manufacturing, confident that our experience with 2-Phenyl-2-Butenal will match the industry’s evolving needs.

    The Direct Manufacturer’s Commitment

    Every molecule of 2-Phenyl-2-Butenal produced under our roof represents a direct dialogue between science, industry, and global trade. The work never stands still; continuous improvement does not finish with a batch sign-off or an equipment upgrade. Through ongoing partnerships with R&D laboratories, regular participation in regulatory developments, and daily attention to product quality, we see this compound not simply as a commodity but as a tool for unlocking innovation.

    Our pride rests not only in final product purity, but in the certainty we build for every end-user—from the first inquiry to the final delivery. True confidence in specialty chemical supply comes from real experience, diligent process oversight, and open communication with those who use these molecules to build something new. The market continues to evolve, but the need for responsible, technically excellent manufacturing only grows—2-Phenyl-2-Butenal remains our answer to those who require more than off-the-shelf solutions.