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2-Phenoxypropionic Acid

    • Product Name 2-Phenoxypropionic Acid
    • Alias Hydratropic acid
    • Einecs 249-862-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    253894

    Chemical Name 2-Phenoxypropionic Acid
    Cas Number 938-94-3
    Molecular Formula C9H10O3
    Molecular Weight 166.17 g/mol
    Appearance White to off-white solid
    Melting Point 48-52 °C
    Boiling Point 149-150 °C at 13 mmHg
    Solubility In Water Slightly soluble
    Density 1.21 g/cm3
    Purity Typically ≥98%
    Smiles CC(C(=O)O)OC1=CC=CC=C1
    Inchi InChI=1S/C9H10O3/c1-7(9(10)11)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,10,11)
    Storage Conditions Store in a cool, dry place, tightly closed

    As an accredited 2-Phenoxypropionic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500g amber glass bottle securely sealed, labeled "2-Phenoxypropionic Acid," displays chemical details, hazard symbols, and batch information.
    Shipping 2-Phenoxypropionic Acid is shipped in tightly sealed containers to prevent moisture absorption and contamination. It should be kept away from incompatible substances and stored in a cool, dry, and well-ventilated area. During shipping, it complies with relevant chemical transport regulations and is usually labeled as a non-hazardous substance.
    Storage 2-Phenoxypropionic acid should be stored in a tightly sealed container, protected from light and moisture, in a cool, dry, and well-ventilated area. Keep the chemical away from incompatible substances such as strong oxidizing agents. Proper labeling and adherence to safety guidelines are essential to prevent accidental exposure, contamination, or degradation of the compound during storage.
    Application of 2-Phenoxypropionic Acid

    Applications of 2-Phenoxypropionic Acid in Industrial Manufacturing

    Our production of 2-Phenoxypropionic Acid (2-PPA) supports precise requirements across several critical industrial segments. Below, we detail recognized downstream application paths, with verified sector standards, formulation details, process roles, and final product forms. We ensure reliable sourcing, traceability, and technical consistency in every batch, aligned with our customers’ advanced demands.

    1. Agricultural Herbicide Intermediate

    2-Phenoxypropionic Acid functions as a key intermediate in synthesizing selective post-emergence herbicides, especially Aryloxyphenoxypropionate (AOPP) types. Producers downstream use this material in esterification steps to make active molecules for grass-weed control in cereals and oilseeds. Our supply supports large-scale technical formulations, complying with environmental and residue directives set by destination countries.

    Industry compliance standards

    • EU Regulation (EC) No 1107/2009 (Plant Protection Products authorization)
    • FAO/WHO Agricultural Pesticide Specifications (FAO/WHO JMPR)
    • ISO 9001:2015 Quality Management
    • SCCS (Scientific Committee on Consumer Safety) guidelines for downstream worker safety

    Typical usage ratio

    • Employed at 30–45% molar for esterification in technical AOPP manufacturing batches, adjusted for target active ingredient purity and process reactor yield.

    Downstream process integration

    • Discharged in bulk to synthesis reactors as the core acid input for direct esterification with alcohol derivatives; batch feeding follows stage-wise integration following exothermic controls.

    Final product types

    • Commercially registered herbicide active ingredients (e.g., fluazifop-P, quizalofop, fenoxaprop)
    • Emulsifiable concentrate (EC) and suspension concentrate (SC) herbicide formulations
    • Pre-packaged technical concentrate for agrochemical distributorship

    2. Pharmaceutical Chiral Building Block

    This material provides an enantiomeric scaffold for contract manufacturing of pharmaceutical intermediates, particularly Arylpropionic acid NSAIDs. GMP facilities downstream utilize enantioselective transformation or derivatization to generate bioactive pharmaceutical intermediates, observing validation, traceability, and impurity profiling under global pharmacopeia requirements.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients
    • USP/NF (United States Pharmacopeia/National Formulary)
    • European Pharmacopoeia (Ph. Eur.) for APIs and starting materials
    • FDA DMF (Drug Master File) requirements for starting materials

    Typical usage ratio

    • Typically used at 1–1.5 molar equivalent per run in chiral synthesis routes. Adjustments depend on yield and target isomer content to minimize racemate formation and meet pharmacopoeial standards.

    Downstream process integration

    • Fed to chiral catalyst stages or used as reference substrate in chromatographic separation for pilot and production APIs; introduced after protection group installation or as a coupling moiety.

    Final product types

    • API intermediates for non-steroidal anti-inflammatory drugs (including custom derivatives)
    • Reference standards for chiral assay calibration
    • Building block for specialty pharmaceutical R&D pipelines

    3. Precision Dye Synthesis (Textile Dyes)

    Specialty dye producers rely on our material as an aromatic hydrophobic chain donor during condensation or coupling in acid and reactive dye synthesis. Controlled feeding and rigorous impurity control are crucial for reproducibility in shade, substrate affinity, and washing fastness of final dyes used in textile printing and coloration. Integration occurs within modern compliance frameworks for worker safety and environmental monitoring.

    Industry compliance standards

    • Oeko-Tex Standard 100 Restricted Substance List
    • ZDHC MRSL (Manufacturing Restricted Substances List)
    • REACH Registration, Evaluation, Authorisation and Restriction of Chemicals—Annex XVII (Aromatic amines restriction)
    • ISO 14001 Environmental Management for effluent control

    Typical usage ratio

    • Loaded at 12–30% weight relative to other aromatic core reactants, with range adjusted based on molecular structure, required color depth, and dye solubility profile.

    Downstream process integration

    • Pumped from storage to pre-coupling units, then directed to controlled temperature condensation tanks for ring closure or side chain addition; process includes real-time analytics for colorimetric output verification.

    Final product types

    • Reactive dyes for cellulosic fibers
    • Acid dyes for wool and nylon applications
    • Direct dyes for viscose or specialty textiles

    4. UV-Curing Monomer Modifier (Coatings and Inks)

    For UV-curable resin systems, formulators use our material to enhance hydrophobicity, flexibility, and flow in high-performance coatings, industrial inks, and non-yellowing finishes. Its aromatic ether structure introduces unique reactivity, tailored by end-use demands, with dosage and compatibility validation performed per production batch.

    Industry compliance standards

    • US FDA 21 CFR 175.300 (Resinous and Polymeric Coatings—where applicable to indirect food contact)
    • ISO 9001:2015 (Production Quality Management)
    • GHS Classification and Labeling (Globally Harmonized System for chemical safety)
    • RoHS Directive (EU 2011/65) for electronic coatings

    Typical usage ratio

    • Added at 3–10% weight ratio in resin or prepolymer syrups. Final quantity determined by viscosity targets, functional group compatibility, and curing speed under specified UV sensors.

    Downstream process integration

    • Dosed directly into resin kettles or ink mixers during pre-polymerization stage; post-addition blending includes in-line dispersing and rheology monitoring prior to UV or EB-cure processing.

    Final product types

    • UV-curable floor and wood coatings
    • Industrial overprint varnishes
    • Specialty inkjet and screen printing inks
    • Automotive clear coat systems

    5. Polymer Additive in High-Performance Plastics

    Manufacturers use 2-Phenoxypropionic Acid as a controlled chain modifier and property-adjusting additive for engineering plastics such as polyesters and copolymers. It imparts tailored polarity and surface activity, critical for blending, impact resistance, and post-application processing. Strict batch accreditation assures suitability for both industrial and regulated end-use products.

    Industry compliance standards

    • ISO 10993-5 (Biological evaluation of medical plastics—if required)
    • ASTM D638 (Plastics tensile property testing)
    • UL 94 (Flammability), if demanded in electronics segment
    • REACH SVHC (Substance of Very High Concern) monitoring

    Typical usage ratio

    • Typical loadings of 0.5–3% by weight in polymer melt blending. Formulation adjusted based on the polyester matrix type, target mechanical characteristics, and downstream compounding protocol.

    Downstream process integration

    • Fed into extrusion or compounding lines through gravimetric dosing units, often pre-blended in masterbatch for small-scale technical polymers or specialty fiber draw production.

    Final product types

    • High-clarity PET and specialty plastic films
    • Technical fiber and yarns for automotive and industrial textiles
    • Impact modified copolyester profiles for medical housings or appliance parts
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    Certification & Compliance
    More Introduction

    2-Phenoxypropionic Acid: From Our Factory Floor to Industry Solutions

    Direct from the Source: Real-World Experience with 2-Phenoxypropionic Acid

    We have spent years at the manufacturing end of organic chemistry, producing both basic and advanced building blocks for different industries. 2-Phenoxypropionic acid stands out in our portfolio, not just because it’s versatile, but thanks to how reliably it delivers results on a production scale. Many of the transformations we run—especially those serving pharmaceutical intermediates, herbicide synthesis, or performance materials—often require a particular profile of chemical stability, purity, and reactivity. 2-Phenoxypropionic acid brings these qualities together, which is why our teams invested both time and resources into refining its production and ensuring consistent quality from batch to batch.

    Our Journey Toward Robust Quality

    We’ve seen how disruptions in purity and trace byproducts can derail downstream production. Over the years, we upgraded our equipment and changed process parameters so every order delivers exactly what our customers expect. At the core, we manufacture 2-phenoxypropionic acid with strict controls to meet or exceed 99.5% purity. This matters for anyone needing reproducibility in their final products—especially for applications such as chiral catalysts, selective herbicides, or even custom monomers used in specialty resins. Low impurity content isn’t just a selling point; it cuts out costly re-work and troubleshooting later down the line.

    Every lot produced undergoes a series of checks: HPLC for purity, loss on drying, melting point, and analysis for specific impurities that crop up given this synthesis route. We continue to tighten specifications and trace outlier results back to root causes, which has become part of our daily routine. This discipline doesn’t just satisfy our regulatory requirements—it lets chemists, formulators, and scientists focus on their end goals rather than double-checking incoming materials.

    Why Our Customers Seek Out This Product

    Over time, we’ve talked with production chemists, researchers, and integrators who rely on this compound for various reasons. Pharmaceutical manufacturers ask for high-purity 2-phenoxypropionic acid to prepare enantiomerically pure products downstream. Its use as an intermediate in terbuthylazine synthesis, for example, stands out—one reaction with an impure acid, and the product caking or clumping can derail an entire batch. Agrochemical formulators also come to us to ensure their process—whether classical or continuous—doesn’t stall because of variable quality, which is a real risk from generic bulk commodities or poorly handled third-party deliveries.

    Our experience grew from these discussions. Sometimes, a new reaction route picks up a trace impurity that’s never caused trouble before. We’ve responded by tightening our recrystallization protocol or revising drying steps to wipe out unexpected water traces. Our lab teams benefit from these improvements, and so do our customers—fewer deviations, steadier processing times, and cleaner downstream results.

    Differences Compared to Commodity Phenoxy Acids

    On paper, 2-phenoxypropionic acid might look like similar compounds—say, 2-phenoxyacetic acid, or bulk grades made in high-throughput plants. The difference plays out in your process—not on technical data sheets, but out in the plant. We’ve visited customer sites and run trials to see firsthand how small variations in side product content can change color stability, viscosity, and reactivity.

    Our process puts the focus on minimizing isomeric contamination and byproducts like phenol or propionic residues. Many vendors settle for what’s easiest to push through commercial reactors, but this introduces more variability than meets the eye. Labs working at the cutting edge, such as those developing chiral drugs or advanced polymer architectures, notice these effects right away. Clean reactions lead to higher yields and more predictable purification steps.

    Listening to Our Customers: Service Beyond Supplying a Chemical

    Manufacturing this acid doesn’t end at the product itself. Companies often tell us about challenges integrating new lots into validated protocols. We don’t just hand off a drum and walk away. Our technical staff have sat in on troubleshooting meetings and shared analytical data, process notes, and handling tips adapted from the dozens of plants we’ve worked with.

    Delivery speed and flexible packaging—options tailored to your consumption rates—become just as important. We offer sealed drums for larger operations, but for R&D or kilo-lab teams, smaller high-integrity containers cut down transfer risk. Each logistics choice reflects feedback from real customers who had issues with other suppliers who only operate as intermediaries.

    Models and Specifications: Practical Implications

    Our standard specification covers 99.5% minimum purity, water content below 0.1%, and a melting point range that provides processing safety. Product is available as a white crystalline powder, free from visible colored impurities. Some customers in regulated sectors ask for even higher purity, and we respond with custom batches where every impurity is traced and quantified.

    For gram-to-ton scale, we offer batch history data, full certificates, and, if required, customized analysis—such as optical rotation for chiral applications or trace metal scans for electronic intermediate use. These requests shaped how we run analytical support, giving each customer access to information rather than only a product label.

    Why Quality Assurance Matters for 2-Phenoxypropionic Acid

    Each use case brings different requirements. Some clients focus on minimizing particulate contamination; others focus on accurate COA traceability for regulatory audits. Our audit teams perform internal cross-verification on representative production runs, comparing supplier raw materials, batch records, and retention samples. Any nonconformance is scrubbed out before final approval. This keeps consistency front and center, letting process chemists at our customers’ sites trust the materials without burning time on extra quality checks.

    A major issue impacting many generic suppliers stems from shortcuts in drying or purification. Even small water residues can trigger unwanted side reactions in moisture-sensitive processes—a reality we’ve seen in custom contract manufacturing projects. Adjusting the post-filtration protocols and fine-tuning temperature ramps during drying has removed these headaches for our customers and ourselves.

    Handling, Storage, and Real-World Considerations

    Over many years, we’ve developed packaging and handling protocols tailored to safety and shelf-life. Each package is filled under nitrogen and sealed, minimizing water uptake. This extra step pays off under real plant conditions—open drums tend to absorb atmospheric moisture, shifting the profile toward unwanted hydrolysis or byproduct formation. To avoid downtimes or off-spec batches, customers store this acid in dry, cool areas, away from strong bases or oxidizers.

    We’ve trained our logistics and customer service teams to communicate these details clearly. Unexpected delays or temperature excursions during transit could upset product profile; we have set up contingency plans for rapid resupply, maintaining product at satellite warehouses. This solves the typical “stock-out” panic, supporting both scheduled and urgent projects.

    Case Studies from Manufacturing Partnerships

    Our involvement doesn’t end with the sale. In one past collaboration with an agrochemical firm, complexity emerged from a side reaction triggered by excess phenol—something missed in generic grades. By cycling multiple trial batches through their synthesis route, our process chemists tuned a distillation step to reduce this impurity and tested each resulting batch using the customer’s own reaction protocol. The project hit its milestones, and the customer gained a more robust process.

    Another example comes from pharmaceutical intermediate makers who needed a starting material with high enantiopurity. We adapted our process and supplied extra analytical support, including spectral data for trace chiral contaminants. This tight loop of feedback between our factory and their lab enabled development and regulatory submissions with full data support.

    Our Ongoing Commitment: Continuous Improvement

    Chemistry never rests, and neither do we. Each improvement we make—whether a new filtration step or an improved analytical protocol—directly reflects experience with reactors, filtration, and logistics. As synthesis methods get more demanding and downstream requirements grow sharper, we add capability to provide tighter controls, better documentation, and faster technical follow-up.

    Feedback from end-users keeps us ground-level about what matters most—timely delivery, reliable product profile, and no surprises. We share technical bulletins highlighting updates to specifications, common troubleshooting issues we encounter, and batch-to-batch changes. Transparency, both for successes and setbacks, earns us the trust we need to build long-term partnerships and keep R&D pipelines moving.

    Supporting Research and Scale-Up

    From kilo-lab trials to multi-ton commercial production, our technical team works with customers to fit each order into their unique process. Whether they need a specific polymorph, a unique formulation, or packaging that fits specialty operations, our approach is hands-on. For start-ups and research institutions, access to full analytical data packages, including NMR, IR, and GC trace analysis, supports grant applications, publications, and patent filings. Our experts answer technical questions directly, drawing on years spent optimizing core processes.

    This support makes a difference during process development and transfer to commercial scale. Since our batch-to-batch variability stays low, scale-up chemists avoid late-game surprises, like a color shift or change in reactivity due to undetected contaminant buildup.

    Minimizing Environmental Impact During Manufacturing

    Environmental responsibility shapes how we run our site—from waste treatment to solvent recovery. The synthesis of 2-phenoxypropionic acid poses some classic challenges: efficient phenol management, reduction of organic solvent emissions, and capturing low-level byproducts before they leave the facility. Continuous investment in waste treatment infrastructure and solvent recycling lets us reduce both costs and environmental footprint. Every bit of spent solvent is documented, recovered if feasible, or neutralized on-site.

    Where possible, we select synthesis steps that reduce waste and simplify downstream processing, and we collaborate with waste handlers who share our commitment to safe, responsible disposal. By matching our process optimization goals to regulatory requirements, we avoid surprises during compliance checks.

    Differences from Resellers and Traders

    Visiting third-party traders’ warehouses or reading their certificates often reveals more variability than advertised. Direct manufacturers like us take responsibility for the entire supply chain—from raw material procurement to packaging and after-sales support. In practice, this shows up as faster turnaround on questions, greater traceability, and the ability to troubleshoot problems at their source—not just relay information.

    We encourage customer audits, offer plant visits, and share quality histories, because we stand behind both our process and our staff. This approach builds the kind of working relationship that’s hard to find from a strictly commercial trader who focuses on price alone.

    Applications We Regularly See

    2-Phenoxypropionic acid serves as a key intermediate for herbicides such as dichlorprop, mecoprop, and others in the aryloxyalkanoic acid family. We often support customers developing chiral intermediates, as this acid’s profile allows direct coupling in the synthesis of enantio-enriched compounds. Formulators in performance resins use it to create novel polymers with improved chemical resistance. Custom applications, uncovered through technical exchanges with clients, keep adding new demand and fresh challenges for our teams.

    We encourage new partners to discuss their unique requirements during initial technical meetings. The earlier we connect, the more we can advise on impurity control, regulatory support, and long-term supply stability.

    Challenges in the Marketplace and Our Approach

    We see too many customers burned by unreliable supply chains or unfamiliar intermediaries. Each time an off-spec lot arrives from a trader, manufacturing lines stall, regulatory teams lose time, and the relationship breaks down. Our goal is to provide full visibility, correct issues before they affect production, and always keep technical discussions grounded in real-world plant experience—whether this concerns a new analytical method or a packaging problem.

    Continued investment in people, plant, and process means we can update protocols, respond to supply disruptions, and scale up or down as needed without compromising core product quality.

    Why Choose Direct Manufacturer Experience

    Every improvement, troubleshooting protocol, and change in specification comes from daily plant practice, not just regulatory checklists. We share lessons learned and help partners adapt to new needs, offering not just a product, but our collective expertise in producing 2-phenoxypropionic acid to the highest standards possible.

    As chemical processes, regulatory environments, and market conditions evolve, we keep pushing for better solutions—because we believe that quality chemistry starts at the source, and we’re proud to keep building on that foundation.