Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-Pentyne

    • Product Name 2-Pentyne
    • Alias Ethylacetylene
    • Einecs 207-919-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    677549

    Cas Number 624-64-6
    Molecular Formula C5H8
    Molar Mass 68.12 g/mol
    Iupac Name Pentyne
    Other Names Ethylacetylene
    Appearance Colorless liquid
    Density 0.696 g/cm³ at 20°C
    Melting Point -104°C
    Boiling Point 55-56°C
    Solubility In Water Insoluble
    Flash Point -17°C (closed cup)
    Refractive Index 1.395 at 20°C
    Vapor Pressure 330 mmHg at 20°C

    As an accredited 2-Pentyne factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-Pentyne is packaged in a 500 mL amber glass bottle with a secure screw cap and chemical hazard labeling.
    Shipping 2-Pentyne should be shipped in tightly sealed containers, under a nitrogen or inert gas atmosphere, to prevent contamination and unwanted reactions. It is classified as a flammable liquid; therefore, shipping must comply with relevant regulations (such as DOT, IATA, IMDG) and utilize appropriate labeling and packaging to ensure safe handling and transport.
    Storage 2-Pentyne should be stored in a tightly closed, properly labeled container in a cool, dry, and well-ventilated area, away from heat, sparks, open flames, and oxidizing agents. It must be kept away from sources of ignition and incompatible substances. Storage areas should be equipped with appropriate fire suppression systems due to the substance's flammability and volatility.
    Application of 2-Pentyne

    Applications of 2-Pentyne in Industrial Manufacturing

    2-Pentyne, as a high-purity alkyne compound, supports key processes in pharmaceutical synthesis, specialty polymer modification, electronic chemical production, agricultural chemical intermediates, and fine chemical synthesis. We manufacture this material to fulfill stringent industry requirements where precise reactivity and defined purity grades are essential for competitive downstream processing.

    1. Active Pharmaceutical Ingredient (API) Intermediate Synthesis

    Leading pharmaceutical producers rely on this alkyne for specific cross-coupling and functionalization steps in the synthesis of heterocyclic intermediates. It acts as a convenient C5 building block, facilitating Sonogashira and other Pd-catalyzed reactions central to small molecule drug frameworks. Process chemists control feed ratios precisely to ensure consistent yields and impurity profiles, meeting the regulatory expectations for multi-stage API production pipelines. The compound enters the route at the cyclization or side-chain introduction stage, allowing for downstream purification and compliance testing.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF monographs for related pharmaceutical intermediates
    • European Pharmacopoeia (Ph. Eur.) regulations
    • 21 CFR Part 211 (US FDA cGMP for finished pharmaceuticals)

    Typical usage ratio

    • 0.8–1.2 molar equivalents relative to halide precursor, adjusted for specific pathway and expected conversion efficiency

    Downstream process integration

    • Alkyne coupling or cyclization in kinase inhibitor backbone assembly
    • Palladium-catalyzed arylation for fragment addition
    • Incorporation in process R&D optimization for route definition

    Final product types

    • Small molecule APIs, such as anti-cancer agents with alkyne linkages
    • Heterocycles in antiviral compound research
    • Advanced pharmaceutical intermediates for further functionalization

    2. Specialty Polymer Crosslinking Additive

    Innovation teams in polymer compounding and material science use the reactivity of this compound in controlled crosslinking reactions, particularly where unsymmetrical C5 units impart fine-tuned mechanical or thermal properties. When formulated into thermoplastics, elastomers, or specialty adhesives, the additive enters at the melt blending or in situ polymerization phase. Its precise incorporation demands technical oversight to balance molecular architecture and performance criteria, especially for high-value engineered materials.

    Industry compliance standards

    • ISO 9001:2015 certified production for specialty substances
    • REACH Regulation (EC) No 1907/2006 Annex XVII compliance
    • RoHS Directive 2011/65/EU for electrical polymer applications
    • UL 94 Standard for safety testing in flame-retardant materials (as applicable)

    Typical usage ratio

    • 0.1–2.0 wt% based on resin mass, with adjustment for polymer type and crosslinking density requirements

    Downstream process integration

    • Direct addition in compounding extruder for thermoplastics
    • Introduced during prepolymer mixing for adhesives
    • Solution blending for advanced filler-modified plastics

    Final product types

    • High-performance elastomeric seals and gaskets
    • Conductive polymer films for flexible electronics
    • Epoxy resins with customized modulus profiles

    3. Electronic-Grade Fine Chemical Synthesis

    Manufacturers in semiconductor and advanced electronics segments require high-purity alkynes for tailored organometallic and precursor synthesis. This material serves as a starting point for lithography-grade resists, specialty etchants, and advanced photoactive compounds. The feedstock purity, handling environment, and trace metal content are critical. Processing teams introduce the raw material at the selective functionalization or organolithium reaction stage, with integrated QA for batch traceability.

    Industry compliance standards

    • SEMI C3: Specification for High Purity Chemicals for the Semiconductor Industry
    • ISO 14644 Cleanroom and associated controlled environments
    • IECQ QC 080000 Hazardous Substance Process Management

    Typical usage ratio

    • Feedstocks used at 95–99.99% purity grades, 0.05–0.5 molar equivalents depending on downstream synthetic complexity

    Downstream process integration

    • Input for organometallic pre-cursor preparation
    • Controlled reactive distillation for high-purity intermediate isolation
    • Inline addition in microreactor chip synthesis

    Final product types

    • Photoresist precursors for integrated circuit fabrication
    • Chemical vapor deposition (CVD) reagents
    • Electronic specialty gases with alkyne moieties

    4. Agricultural Chemical Intermediate Manufacturing

    Leading agrochemical companies process this C5 alkyne to construct selective herbicide and insecticide intermediates. The compound’s reactivity profile enables precision introduction into multi-functional frameworks, often via metal-catalyzed additions or controlled substitution. Production lines monitor batch dosing relative to substrate reactivity and downstream step complexity. Material handling integrates at the hydrogenation or halogenation stage, aligning with industry practice for scalability and regulatory registration.

    Industry compliance standards

    • FAO/WHO technical specifications for pesticide active ingredients
    • ISO 9001 and ISO 14001 (environmental management) for synthesis facilities
    • EU REACH registration for agricultural raw materials
    • OECD Good Laboratory Practice (GLP) for developmental studies

    Typical usage ratio

    • 1.1–1.3 stoichiometric equivalents in coupling or chain extension step, tailored for yield optimization and regulatory specification

    Downstream process integration

    • Entrance at halogenation or partial hydrogenation in core structure assembly
    • Use in batch reactors with in-line GC for intermediate identification
    • Integration in pilot-plant scaleup for pre-commercial process validation

    Final product types

    • Pyridine-based herbicide intermediates
    • C5-alkyne functionalized insecticide scaffolds
    • Fine agrochemical intermediates for selective targeting molecules

    5. Advanced Fine Chemical and Perfume Ingredient Production

    Specialty fine chemical producers utilize this compound as a controlled functional group transfer agent and scaffold builder in flavor and fragrance ingredient synthesis. Its well-defined triple bond allows reliable access to rare lactones, aldehydes, and alcohols through selective chemical transformation. Workflows frequently batch-dose the reagent in controlled settings during Grignard reactions or partial reductions, tailoring process temperatures and catalyst loads to preserve desired side-chain configurations.

    Industry compliance standards

    • IFRA Standards for ingredient safety and purity
    • ISO 22716:2007 Cosmetics — Good Manufacturing Practices
    • EU Regulation (EC) No 1223/2009 on cosmetic products (for applicable fragrance use)
    • Hazardous Materials Regulations (HMR; 49 CFR Parts 171-180) for shipping and storage

    Typical usage ratio

    • 0.05–0.5 molar equivalents in fine chemical syntheses, ratio set by final compound structure and process yield

    Downstream process integration

    • Dosed during Grignard reagent formation for side-chain extension
    • Introduced in partial reduction steps to manufacture C5 flavor molecules
    • Integrated in continuous or semi-batch reactors for scale-up and pilot runs

    Final product types

    • Cyclopentenone derivatives for fragrance creation
    • C5-aldehyde intermediates for high-grade flavors
    • Alcohol building blocks in perfumery and aroma applications
    Free Quote

    Competitive 2-Pentyne prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-Pentyne: A Manufacturer’s Perspective on Production and Applications

    Overview: Working with 2-Pentyne in Daily Operations

    After years spent synthesizing a diverse palette of chemicals, 2-pentyne stands out as a core specialty alkynic hydrocarbon in our catalog. The chemical formula C5H8 and structure CH3C≡CCH2CH3 describe a material that demonstrates interesting behavior, both in the plant and in downstream chemical processes. Each batch runs clear and colorless, reflecting high standards for purity—a point that distinguishes our product from cracked or recycled grades sometimes found through less experienced sources. In practice, such consistency does more than look good; it makes downstream synthesis and research both more predictable and safer.

    2-Pentyne appears in our reactors most often with a minimum purity above 98%. With GC and NMR as constant companions, we track impurities tied to side-chain isomers, unsaturated hydrocarbons, and residual solvents. Handling and analysis rest in the hands of operators who take pride in mastering alkyne chemistry—an area where uncontrolled reactions or contamination can result in unstable mixtures or dangerous conditions. Where some plant operations rely on high-throughput, our focus on specialty alkynes forces close attention to every kilo, since even trace byproducts might ruin a sensitive organometallic downstream use.

    Over the years, we’ve supplied 2-pentyne to both large-scale chemical innovators and university research teams. Some rely on it for developing new ligands and catalysts that require a clean triple-bonded starting material. Others push it further into specialty polymers, agricultural solutions, and pharmaceutical intermediates. Whatever the application, direct feedback from chemists teaches us that skipping corners in purification or failing to confirm batch consistency results in headaches for those working in the lab or on scale.

    Production Insights: Expertise Shapes Safer, More Reliable Alkynes

    Each run starts with the careful monitoring of precursors, temperature, and reaction time within our alkyne-optimized equipment. Alkynes demand respect; small mistakes can cause pressure build-up or dangerous byproduct formation. Those not hands-on with distillation or gas handling don’t always appreciate just how sensitive the refining of 2-pentyne can get, so we keep checklists from pre-start to collection. Our team trains for weeks before taking responsibility for routine sampling or analysis because errors carry more than financial costs.

    Most of the 2-pentyne in circulation worldwide comes from reactions such as the double dehydrohalogenation of 2-pentanol or careful cracking of longer-chain hydrocarbons under controlled conditions. Sourcing high-purity feedstock and strong bases drives yield and safety, so our procurement team keeps close tabs on suppliers and regularly audits incoming materials. With every batch that reaches packing, our reputation travels with the product in industries that have no tolerance for unanticipated reactivity or trace contamination.

    Model and Logistics: How We Package 2-Pentyne for Industrial Use

    Our clients don’t just value the purity of chemicals—they often depend on predictable packaging and shipping. We deliver 2-pentyne in high-integrity sealed flasks, pressurized cylinders, and bulk containers for larger process facilities. Since 2-pentyne forms explosive mixtures in air and can react violently with strong oxidizers and halogens, our packaging and labeling reflect an ingrained culture of safety. By investing in redundant pressure-relief and inert gas blanketing, we avoid the kind of shipping incidents that reflect poorly on both supplier and customer.

    In some markets, especially outside the main industrial hubs, we’ve witnessed customers purchase lower grade alkynes from traders that don’t appreciate the risks of shipping bulk alkynes in untested drums or tanks. In contrast, we track every drum and cylinder’s integrity, maintain MSDS and COAs tied to specific lots, and give customers guidance for safe storage. Those who work with 2-pentyne quickly learn that compromises in logistics can cost more than time; it risks safety and project outcomes.

    Specific Applications: Bridging Laboratory and Plant-Scale Innovation

    Chemists reach for 2-pentyne because of its strong triple bond and straightforward five-carbon backbone. In our own pilot facilities, we frequently see it serve as a starting point for the synthesis of substituted pentenes, cyclization reactions, and as a building block in catalytic transformations. Unlike bulk feedstock alkynes such as acetylene, 2-pentyne’s performance in these reactions comes from its moderate chain length and relative lack of terminal acidity.

    Research teams tell us they value our 2-pentyne for metal-catalyzed couplings—especially for generating functionalized dienes or constructing ring systems. Some studies leverage the molecule in studies of alkyne metathesis or in the synthesis of ligands for transition metal catalysts. Others push for its use in optimizing cross-coupling reactions, taking advantage of the central triple bond to unlock new synthetic routes.

    A few industrial buyers diverge from the norm. In agricultural chemistry, 2-pentyne’s unique structure lets it function as a key precursor in synthesizing herbicidal or pesticidal agents. We have seen it appear as a handle in stepwise syntheses for unique agrochemicals, where reactivity and chain length both matter for final performance. In specialty elastomer and polymer development, the alkyne group enables unique chain-growth behaviors, opening up new directions for advanced materials.

    Safety and Handling: Why Experience Matters in Alkynes

    Handling 2-pentyne isn’t like working with benign solvents or standard alkanes. A triple bond introduces greater reactivity, and the molecule combines low flash point with volatility. Both lab-scale and bulk users regularly consult our in-house team to avoid common mistakes such as storing near oxidizers or open flames. In our own operations, we run double-checks at every transfer—inert atmospheres using nitrogen or argon, grounding procedures, and continuous monitoring for leaks or pressure build-up.

    Unlike some bigger hydrocarbons, accidental exposure to small amounts of 2-pentyne vapor can mildly irritate mucous membranes or eyes, driving home the value of working in well-ventilated hoods and maintaining PPE compliance. Our SOPs—born from long work in the field—call for ready spill kits, regular training, and clear marking of all storage vessels. Distance from ignition sources, routine gas detection in storage, and a conservative approach to quantities—all learned through daily practice.

    Comparisons: 2-Pentyne Versus Other Alkynes and Olefins

    Within our product range, 2-pentyne stands apart from terminal alkynes like 1-pentyne or smaller alkynes such as acetylene or propyne. Terminal alkynes carry their triple bond at the end, which gives rise to more pronounced acidity—an advantage or disadvantage, depending on reaction goals. 2-Pentyne’s internal triple bond resists protonation or facile deprotonation, so it offers more selectivity in reactions that seek to avoid side pathways.

    Compared to unsaturated olefins like pentene or hexene, the triple bond gives 2-pentyne heightened reactivity in addition reactions with metals and halides. Where simple alkenes operate under milder conditions, 2-pentyne often unlocks faster, more robust changes in molecular scaffolding, letting chemists introduce new functional groups or rearrange carbon chains with greater control.

    More complex isomers such as 3-pentyne exist, but 2-pentyne’s placement of the triple bond provides a sweet spot for industrial transformations, especially when working toward certain pentene derivatives or cyclization products with regular substitution patterns. While a few bulk commodity outlets focus on simpler alkynes, demand for 2-pentyne reflects its predictable reactivity and intermediate molecular weight, which supports both volatility for gas-phase reactions and ease of handling under regulated plant conditions.

    Feedback-Driven Improvements: Lessons from Downstream Users

    Over the years, close contact with research groups and plant chemists shaped our approach to supporting 2-pentyne applications. In one instance, a pharmaceutical partner detected trace impurities in a batch that other vendors missed. Rather than pass blame, our team re-examined our own process controls and dialed in a new purification step. That extra effort soon became routine for all outgoing material, with batch analysis paperwork now matched to individual lots.

    We continually adapt our process in response to new research. Recent requests for diverted side-cut fractions have triggered a review of how we recover and recycle byproducts, aiming to lower waste and meet stricter environmental targets. Customers working at the edge of innovation—be it in advanced materials or green chemistry—trust us only as long as we keep delivering on both purity and openness to improvement.

    As more chemical customers pursue sustainability, we’ve begun incorporating green metrics into our production cycle for 2-pentyne. This move includes energy-use monitoring, solvent recycling, and improved vapor recovery. The feedback loop remains direct and personal; our staff regularly visits client sites to watch processes in action, learning about both successes and bottlenecks. Each visit prompts tweaks to formulations or recommendations for better shelf-life or handling.

    Market Realities: Sourcing and Global Chemical Flows

    The global market for alkynes has its cycles, and 2-pentyne moves through it as both a specialty item and semi-bulk intermediate. During tight supply periods, customers who lock in standing contracts insulate themselves from price spikes and delays triggered by geopolitical events or raw material shortages. For export markets, we match regulatory documentation and batch analytics with wider compliance needs, from REACH registration in Europe to customs paperwork in Asia.

    Supply-side disruptions have shown their impact; a missed shipment or feedstock backlog in one part of the world ripples across research and production timelines. Through redundancies in warehousing and close relationships with raw material producers, we can buffer against most shocks. That said, answering technical queries quickly remains one of our key strengths, letting clients avoid poorly informed substitutions that might introduce lower-grade materials or safety hazards.

    Regulatory and Environmental Considerations

    Legislation covering volatile organics, hazardous shipping, and chemical traceability continues to shape every shipment of 2-pentyne from our site. Years working alongside regulatory agencies taught us that cuts to paperwork or documentation almost always cost more in the end. Each outgoing order includes full traceability back to specific batch runs, and our staff stays updated on changes to region-specific toxicology or environmental restrictions.

    Across the industry, a shift toward lower-impact chemical manufacturing has re-shaped the way 2-pentyne enters the market. Clients show increased interest in life-cycle data, residual VOC emissions, and end-of-life handling. We’ve worked with partners to pilot closed-cycle packaging, inert return drums, and on-site vapor capture. Each of these projects not only meets external regulatory goals but fosters new long-term partnerships grounded in practical sustainability.

    Future Developments: Research, Supply Chain, and Customer Collaboration

    Research groups continue to find new ways to harness 2-pentyne’s core chemical properties. We support these projects by providing not just the compound, but also the technical knowledge that comes from hands-on production—how subtle feedstock variations impact catalytic behavior, why certain impurities disrupt polymerization, or what storage temperatures maximize shelf-life. Many breakthroughs come from collaboration between manufacturers and end-users rather than generic solutions.

    We see an uptrend in demand driven by both emerging economies aiming to build their own specialty chemical sectors and established firms optimizing known syntheses. Today’s buyers ask sharper, more technical questions, showing how the market values both performance and transparency. In response, we enhance our technical support and share process data—whether about purification yields or trace contaminant thresholds—turning commercial transactions into deeper partnerships.

    Sometimes customers need small lots for trial work, then later switch to drum shipments as projects reach pilot scale. Our operations maintain flexibility by dedicating certain lines to small-scale production with fast changeover, keeping plant downtime low while still serving a diverse customer base. The goal never shifts: deliver reliable, high-specification 2-pentyne matched to a real-world project’s needs, grounded in long-term experience with the material and its applications.

    Conclusion: Value Through Deep Knowledge and Reliable Practice

    Crafting and supplying 2-pentyne requires more than installing a reactor and filling orders. Real insight comes from years of repetitive synthesis, listening to project chemists, and chasing better yields. We fine-tune everything from quality control to how a flask leaves the warehouse, and carry every lesson forward—sometimes prompted by a customer’s late-night email, other times by internal checks that prevent problems from reaching the loading dock.

    What sets our approach apart is a combination of respect for chemical risk, relentless attention to purity, and a determination to learn both from success and setback. In the world of alkynes, 2-pentyne remains a precise tool. Getting it right rewards everyone in the supply chain—the manufacturer who keeps danger at bay, and the end user who transforms a kilo into tomorrow’s innovations.