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2-Nitromesitylene

    • Product Name 2-Nitromesitylene
    • Alias 2-Nitro-1,3,5-trimethylbenzene
    • Einecs 221-047-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    840996

    Chemicalname 2-Nitromesitylene
    Casnumber 603-76-9
    Molecularformula C9H11NO2
    Molarmass 165.19 g/mol
    Appearance Yellow crystalline solid
    Meltingpoint 52-54 °C
    Boilingpoint 273-275 °C
    Density 1.17 g/cm3
    Solubilityinwater Insoluble
    Flashpoint 130 °C
    Smiles Cc1cc(C)c([N+](=O)[O-])c(C)c1
    Refractiveindex 1.585 (at 20 °C)
    Pubchemcid 12182

    As an accredited 2-Nitromesitylene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 100 mL, with tamper-evident cap and hazard labels displaying flammable, toxic, and environmental warning symbols.
    Shipping 2-Nitromesitylene is shipped as a hazardous material in accordance with relevant regulations. It should be packed in tightly sealed, chemical-resistant containers and clearly labeled. The shipment must comply with UN regulations, typically under UN1663, and be transported by trained personnel to minimize risks from spills, leaks, or exposure during transit.
    Storage 2-Nitromesitylene should be stored in a tightly closed container in a cool, dry, well-ventilated area away from sources of ignition, heat, and incompatible substances such as strong oxidizers. Protect from direct sunlight and moisture. Proper labeling is essential, and the chemical should be kept away from acids and bases. Safety protocols and local regulations for storage of hazardous chemicals must be followed.
    Application of 2-Nitromesitylene

    Applications of 2-Nitromesitylene in Industrial Manufacturing

    2-Nitromesitylene acts as a fundamental intermediate in multiple specialized chemical conversion processes. As a dedicated manufacturer, we consistently serve downstream partners in fine chemicals, pigments, agrochemical synthesis, pharmaceutical intermediates, electronic chemicals, and specialty polymer production through precise, application-driven material preparation and quality assurance.

    1. Synthesis of Agrochemical Intermediates

    Downstream producers frequently select this raw material to construct key building blocks in selective herbicide and fungicide synthesis. Its methylated aromatic structure, combined with the nitro functional group, enables developers to localize substitution patterns, facilitating efficient chlorination, hydrolysis, and amination steps for next-generation active compounds. Process chemists adjust input ratios to control impurity profiles and maximize conversion yield during scale-up of target agrochemical intermediates.

    Industry compliance standards

    • ISO 9001:2015 Quality Management System
    • REACH Regulation (EC) No 1907/2006
    • China Pesticide Registration Requirements (ICAMA)
    • FAO Specification for Technical Concentrates

    Typical usage ratio

    • 0.8–1.2 molar equivalents to targeted aromatic intermediates, adjusted based on downstream substitution route and byproduct minimization

    Downstream process integration

    • Fed into aromatic nitration, chlorination, or amidation reactors as the primary functionalized substrate in multi-step agrochemical intermediate synthesis
    • Employed during closed-system batch or continuous flow processes with temperature and pH controls for selectivity

    Final product types

    • Precursor compounds for triazole herbicides
    • Fungicide synthetic building blocks
    • Chemical intermediates for select pesticide actives

    2. Dye and High-Performance Pigment Manufacturing

    Producers in the coloring agent sector use our material in the formulation of azo dyes and advanced pigments. Its robust electron-withdrawing and donating substitution pattern supports direct coupling chemistry and, in certain process routes, protects core structures during further nitration or reduction. Because of its consistent batch purity, color developers achieve precise shade reproducibility and high tinctorial strength in premium end-use pigment types.

    Industry compliance standards

    • Standardized methods under DIN EN ISO 4618 for pigments and extenders
    • Oeko-Tex Standard 100 (chemical safety for textile additives)
    • REACH Annex XVII (restriction on certain azo colorants)

    Typical usage ratio

    • 0.5–1.7 molar equivalents per coupling partner, modulated based on chromophore type and dye yield optimization

    Downstream process integration

    • Charged into diazotization or coupling units as the nitroaromatic source in azo pigment manufacture
    • Actively protects key intermediates during complex aromatic transformation stages

    Final product types

    • High-performance organic pigments (red, orange, yellow classes)
    • Azo and metal complex dyes for inks and plastics
    • Coloring agents for technical coatings

    3. Pharmaceutical Intermediate Production

    Our facility supplies this raw material to innovator and generic pharmaceutical manufacturers engaged in the production of specialized intermediates for non-steroidal anti-inflammatory drugs (NSAIDs) and experimental oncology molecules. Unlike traditional aromatic nitro compounds, the methylation pattern enables regioselective downstream reductions and ring-closing reactions under controlled hydrogenation or catalytic systems. This enables process chemists to streamline complex syntheses, reducing step count and improving throughput for critical API intermediates.

    Industry compliance standards

    • ICH Q7 GMP Guidelines for Active Pharmaceutical Ingredients
    • USP–NF Monographs (as applicable for intermediates)
    • Chinese Pharmacopoeia General Requirements on Starting Materials

    Typical usage ratio

    • 0.9–1.3 molar equivalents with respect to core scaffolds, adjusted for targeted yield and impurity specifications under cGMP conditions

    Downstream process integration

    • Introduced into reduction or amination vessels as the core precursor during multistep synthesis of pharmaceutical building blocks
    • Batch and continuous hydrogenation processes for targeted functional group transformation

    Final product types

    • Key intermediates for NSAIDs
    • API precursors for oncology research compounds
    • Methylated aminobenzene-type intermediates

    4. Electronic Chemicals and Liquid Crystal Material Synthesis

    Leading electronic chemical manufacturers adopt this compound in the preparation of advanced liquid crystal monomers and specialized aromatic components for display applications. The molecular symmetry and precise substitution facilitate introduction into downstream Friedel–Crafts acylation or Suzuki coupling reactions without destabilizing the aromatic core, supporting exceptional purity and performance in high-value optoelectronic materials. Stringent batch traceability and metal impurity control are enforced throughout the handling process.

    Industry compliance standards

    • ISO 9001:2015 and ISO 14001:2015 certified electronic chemical production
    • IECQ QC 080000 Hazardous Substance Process Management
    • JIS C6107 and RoHS Directive for electronic material safety

    Typical usage ratio

    • 0.4–1.1 parts per part of coupling partner substrate, optimized for monomer reactivity and bulk property consistency

    Downstream process integration

    • Enters coupling or acylation steps during the backbone assembly for liquid crystal monomers and display chemicals
    • Applied as a masked aromatic core in engineering plasticizer ingredient production

    Final product types

    • Monomeric components for LCD and OLED displays
    • Advanced optoelectronic active compounds
    • Chemical building blocks for polymeric electronic materials

    5. Specialty Polymer Additives and Resin Modification

    Resin formulators adopt this material in polymer modification, particularly for introducing specific steric bulk or altering functional group distribution in high-performance resins. The nitroaromatic structure boosts reactivity in condensation and grafting reactions, empowering engineers to design modified polymer backbones for specialty coatings, adhesives, or elastomers. Our consistent impurity control supports high end-use reliability in demanding industrial applications.

    Industry compliance standards

    • ISO 14001:2015 for environmental management in speciality polymer production
    • EN 71-3 for additives in coatings and toys
    • REACH Regulation on monomers and additives

    Typical usage ratio

    • 0.3–1.5 weight percent in final resin feed, controlled according to target mechanical or chemical properties

    Downstream process integration

    • Added during prepolymer preparation or reactive blending for backbone functionalization
    • Utilized as a graft copolymerization precursor

    Final product types

    • Modified epoxy and phenolic resins
    • Specialty adhesives and sealants
    • High-resistance polymer coatings
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    Certification & Compliance
    More Introduction

    2-Nitromesitylene: From Our Plant to Your Process

    Insights From the Factory Floor

    Ask anyone on our team about 2-Nitromesitylene and you won’t get a textbook summary. This compound—aromatic, bright, persistent—marks more than a line on a catalog. Every batch traces a route through our reactors, filtration rigs, drying ovens, inspection stations, and into the hands of chemists who demand reliability. For decades, our experience with nitroaromatics has taught us that each process parameter influences downstream results. Heat profile, catalyst purity, pressure variation, feedstock consistency, and—often underappreciated—equipment cleaning routines. From raw mesitylene drum to the rich, gold-tinged powder that fills our bags, we apply a hands-on approach informed by both lab notes and production records.

    The model we consistently supply is 2-Nitromesitylene (CAS 603-11-2), known for its precise arrangement of methyl and nitro groups on the benzene ring. It’s this regioselectivity—achieved through tightly managed nitration sequencing—that keeps impurity levels under control. Using high-purity mesitylene as our base, we’ve adjusted the acid concentration and optimized contact time over years of trial. Every finished lot passes instrumental checks on GC-MS and HPLC, targeting residual mono- and dinitro impurities well below 0.5%. Water and acidity sit in the low ppm range. These are not assurances driven by spec sheets; they’re benchmarks our QC chemists check in person. Sometimes a seasoned operator will spot a subtle color difference or notice a slight clumping—signs that merit an extra round of purification or drying. Automation covers much of what repetitive tasks need to ensure, but under our roof, human judgment still plays a vital role.

    Why Quality Matters in Aromatic Nitration Products

    In nitroaromatic chemistry, the smallest deviation can trip up scale-up partners. The sharp melting point of our 2-Nitromesitylene reflects purity, typically cited between 74 to 76°C. We work to ensure these physical qualities remain tight year-round, regardless of shifting humidity or temperature in our region. Stability and ease of handling matter as much to our team as to any downstream formulator. Consistently low water content guarantees the compound doesn’t cake on the shelf or react unpredictably in a customer’s reactor. Particle size polishes off the final touch. Most requests land in the 20–120 mesh range, striking a balance between dissolving power and ease of dispensing. Special sieving isn’t outsourced. We run it ourselves so we know exactly how much fine dust or oversized grain leaves the door.

    End users often ask for assurance that our 2-Nitromesitylene matches specs with every batch, not just at product launch. That thread of trust starts with transparency: full test reports accompany all outgoing material, showing exact percentages and analytical data for color, melting range, assay, moisture, acidity, and trace contaminants. Paperwork has its place, but we don’t rely on documents alone. Many customers visit our facility to see our production lines and speak with the team—engineers, supervisors, QC, and pack-out specialists. Real conversations build real confidence. If a batch looks off in their own synthesis labs, callers reach actual production staff, not automated menus.

    Supporting Downstream Synthesis: The Value of Predictable Feedstocks

    2-Nitromesitylene earns its place in chemical factories, research labs, and specialty material shops because its three methyl groups—locked to the benzene ring—limit unwanted side reactions. That selectivity pays off most clearly in agricultural chemistry and pharmaceutical intermediates. Technical teams rely on it for the preparation of various substituted anilines, carboxylic acids, and fine aromatic derivatives. Sometimes we see use in pigment manufacturing, where subtle changes in precursor quality influence batch hues and purity grades. No matter the application, feedstock predictability reduces rework and scales up efficiently.

    Long experience has taught us that even top-tier organizations sometimes miss the subtle link between source material purity and process reliability. Problems that start at the level of an aromatic nitro compound can haunt operations much further downstream—yield losses, impurity carryover, color deviation, even foul odors in the final product. Our feedback loop for adjusting upstream processing began not as a marketing push, but from real production headaches—both our own and those reported by long-time customers. We don’t see requests for clarification as burdens. Instead, we dissect each complaint or odd result, walking through every parameter shift until we pinpoint the root. Sometimes the solution comes down to extra pre-filtration or minor tweaks to the recrystallization solvent ratios. Every shift in production ripples out to customer outcomes.

    Direct Manufacturer Commitment: Consistency, Traceability, Access

    Being a chemical manufacturer—not a trader—carries responsibilities. The 2-Nitromesitylene bags leaving our warehouse reflect the exact process conditions in our own reactors. Each batch’s production date, technician, and even shift information gets retained for years. Any deviation, anomaly, or field complaint triggers batch-specific reviews. Traceability stands at the core of our operation. It’s never a matter of finding out “who sourced what” from a supplier chain. Every drum, pail, or carton can be traced back directly to our batch logs.

    Some customers have used the same nitroarene sources for decades. Brand switches, substitution, and relabeling sometimes bring unknowns—shifting assay values, cloudy solutions, or unexpected residue on filtration. We know that frustration. Our approach? Total process control and open communication. If your end use requires a certain polymorph, or if physical flowability needs tuning, our production team talks directly with your technical staff. Problems don’t shuttle to middlemen or brokers. Real solutions come from experienced manufacturers who recall your last lot number, not from scripts.

    Comparison With Other Nitroarene Products

    Most nitroarenes share signature traits: aromatic base, electron-withdrawing nitro function, certain volatility risks. 2-Nitromesitylene stands out in our catalog for its methyl group arrangements. Structural isomers or related compounds—like 3-nitrotoluene, 2,4-dinitrotoluene, or ortho-nitroanisole—show different reactivity, solubility, and volatility. Unlike mono- or dinitrotoluenes, the symmetric methyl substitution confers both steric protection and particular electronic effects, making 2-Nitromesitylene less reactive in some side-chain oxidation or halogenation processes. It fits applications demanding precise downstream selectivity—where other nitroarenes might foster unwanted byproducts or lower selectivity yields.

    In our experience, customers who tried replacing 2-Nitromesitylene with structurally similar aromatics often report less predictability in further transformations. Melt purity, color spectrum, and acid/base stability consistently set 2-Nitromesitylene a step apart. Some competitive products reach the market with higher residual starting material or off-spec isomeric content, especially when produced outside rigorous reactor controls. The compound’s relatively high melting point aids in shipping during humid seasons, reducing risk of leakage or softening, even when storage conditions fluctuate.

    Process Improvements: Learning From Production History

    Our journey with this molecule didn’t start from perfect graphs or flawless protocols. Early runs saw more byproduct dinitro content, inconsistent granulation, and even rare off-odors traced to aged stock acid mixtures. Incremental learning happened on the line. Adjusting the time profile, phasing in new filtration cloths, and switching to fresher acid sources yielded immediate, measurable improvements. Lab-scale tweaks sometimes failed to scale up, and production staff noted firsthand how slight ambient humidity shifts or longer filter hold times influenced final appearance.

    One crucial process upgrade came after persistent customer feedback on batch-to-batch color drift. Investigation traced the hue change back to minuscule iron pickup during filtration. A switch to inert-lined filtration components didn’t just improve product brightness—it noticeably extended shelf life due to reduced trace contamination. Every year, we review logs for deviations and share actionable findings with partners. These improvements stem directly from operational transparency and ongoing dialogue between supplier and user, not from generic optimization charts.

    Beyond the Products: Responsible Manufacturing and Transparency

    Producing aromatic nitration products implicates much more than conversion efficiency or end-assay. Environmental, health, and operational safety never sit on the periphery for direct manufacturers. Our site’s operations comply with all local and national environmental discharge and emissions standards. Waste acids get processed and recycled in-house wherever feasible, cutting both cost and ecological impact. While visitors might note the efficiency of automated reactors and packaging machines, we place as much emphasis on ventilation upgrades, on-line monitoring for leaks, and responsible chemical storage as on finished product handling.

    To minimize risk along the supply chain, we enforce strict rules on transport preparation. 2-Nitromesitylene ships in double-lined, moisture-sealed drums or cartons. Each container receives tamper-proof closure—no exceptions. Warehousing limits transit temperature swings and sunlight exposure, since nitro compounds tend to destabilize if mishandled. All warehouse and logistics staff receive direct, detailed training—not just certification—on handling and spill emergency responses. We see safety practices not as regulatory hurdles but as vital workplace culture that protects both our workers and yours.

    Application Stories: Field Experience and Customer Outcomes

    Countless synthesis teams have relayed stories where one minor switch in nitroaromatic supplier caused major downstream effects—unexplained yield drops, unexpected side fractions, finicky crystallizations, even sticky mixers or odd product hues. Many problems surface only after hundreds of kilograms pass through. Our technical support responds quickly. Industrial users have even forwarded real-time chromatograms and batch notes to us for troubleshooting. We treat field cases as opportunities for product and process refinement.

    Academic researchers also use our 2-Nitromesitylene, finding consistent results in multi-step aromatic syntheses and structure–activity relationship studies. Smaller scale or research lots receive the same production care, as even 500-gram runs must match the physical and chemical expectations set by much larger industrial orders. Through continuous collaboration—visits to customer plants, round-table meetings, on-site pilot trials—we’ve helped teams adjust temperature profiles, solvent sequences, or reactant addition rates to get cleaner conversions when needed.

    Continuous Feedback: Shaping Future Production

    Feedback from users directly drives our continuous improvement cycle. Recent years have brought demand for ever-tighter residues—pushing us to add off-line purification and new, finer-mesh sieving lines. Customer questions about secondary impurity build-up led us to invest in new purity analysis methods, going beyond standard QC to include advanced spectroscopy and extra stability tracking. Not every change filters down overnight; scaling innovations safely keeps the process robust as we inch improvements from kilo-labs to bulk runs.

    Technical partnerships don’t just polish the product. They strengthen our knowledge base and broaden the application palette for 2-Nitromesitylene—often uncovering new material science applications or custom catalyst protocols that benefit the wider marketplace. Building a process that’s both flexible for innovation and anchored in traceable consistency requires deeper production understanding than mere trading can offer.

    What Partners Value in Genuine Manufacturing Relationships

    Consistency—a word often used, but for us, embodied by every step of production. This extends to how we store, document, and communicate batch data. Customers expect not just purity and prompt delivery; they expect reliability proven through years of repeat orders. We offer a relationship founded on openness, technical dialogue, and practical support at every stage—from early R&D evaluation to high-volume supply chains.

    While marketing copy often focuses on technical metrics, the real-world journey of 2-Nitromesitylene starts and ends with the people making and using it. Every kilogram moves with stories of iterative improvements, troubleshooting, openness, and a commitment to better chemistry—practiced daily in our plant. Being a manufacturer means carrying the full cycle from synthesis through to user satisfaction and long-term process gains, with integrity shaping every batch.