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2-Nitroaniline-4-Sulfonic Acid Sodium Salt

    • Product Name 2-Nitroaniline-4-Sulfonic Acid Sodium Salt
    • Alias 2-Nitro-4-aminobenzenesulfonic acid monosodium salt
    • Einecs 242-870-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    599694

    Product Name 2-Nitroaniline-4-Sulfonic Acid Sodium Salt
    Chemical Formula C6H5N2O5SNa
    Molecular Weight 258.17 g/mol
    Appearance Yellow to orange powder
    Solubility In Water Soluble
    Melting Point Decomposes before melting
    Cas Number 127-68-4
    Synonyms Sodium 2-nitro-4-aminobenzenesulfonate
    Storage Conditions Store in a cool, dry place
    Purity Typically ≥98%
    Ph Neutral to slightly alkaline
    Stability Stable under recommended conditions
    Uses Dye intermediate, chemical synthesis
    Hazard Class Irritant
    Color Index Number None assigned

    As an accredited 2-Nitroaniline-4-Sulfonic Acid Sodium Salt factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Packaged in a 500g sealed amber HDPE bottle with a tamper-evident cap, labeled with safety, chemical identification, and hazard information.
    Shipping `2-Nitroaniline-4-Sulfonic Acid Sodium Salt` is shipped in tightly sealed, corrosion-resistant containers to prevent moisture exposure. Packages are clearly labeled and compliant with all relevant chemical transport regulations, including appropriate hazard symbols if necessary. Ensure handling by trained personnel and store in a cool, dry, well-ventilated area during transit.
    Storage **2-Nitroaniline-4-Sulfonic Acid Sodium Salt** should be stored in a cool, dry, and well-ventilated area away from heat, moisture, and incompatible substances such as strong oxidizers. Keep the container tightly closed and properly labeled. Avoid exposure to direct sunlight. Use only with appropriate personal protective equipment and follow all relevant safety guidelines for handling chemicals.
    Application of 2-Nitroaniline-4-Sulfonic Acid Sodium Salt

    Applications of 2-Nitroaniline-4-Sulfonic Acid Sodium Salt in Industrial Manufacturing

    2-Nitroaniline-4-sulfonic acid sodium salt plays an essential role in several specialized chemical sectors, especially where high specificity for diazo coupling, intermediate stability, and controlled reactivity are necessary. As a direct manufacturer, we supply this intermediate for established downstream uses in regulated industrial environments where clarity of performance, assured compliance, and consistency of formulation are critical.

    1. Azo Dye Intermediates for Reactive and Direct Textile Dyes

    Textile dyestuff producers utilize this sodium salt as a key diazo component for synthesizing high-performance azo dyes, valued for colorfastness and chromatic precision in cellulose and polyamide fibers. The compound introduces a controlled sulfonate group, ensuring solubility and reactivity for dyeing processes targeting international clothing and home textile markets. Dyehouses demand narrow consistency on sulfonation degree for batch reproducibility.

    Industry compliance standards

    • Oeko-Tex® Standard 100 (product class I–IV)
    • ZDHC MRSL (Manufacturing Restricted Substances List)
    • EU REACH Annex XVII (Aromatic amines restrictions)
    • GB/T 17592-2011 (Chinese National Standard for banned amines in dyed textiles)

    Typical usage ratio

    • Applied at 0.4–1.6 molar equivalents per dye molecule, depending on shade depth, molecular design, and fiber affinity; color chemists directly match to primary coupling partners and fastness targets.

    Downstream process integration

    • Added during diazotization and subsequent azo coupling stages; introduced as a cold or neutral aqueous solution to minimize byproduct formation and maximize chromophore yield; process steps tightly monitored by in-process HPLC.

    Final product types

    • Reactive dyes for cotton and viscose
    • Direct dyes for paper and regenerated cellulose
    • Acid dyes for nylon and wool
    • Azo pigments for plastics and digital inks

    2. Leather Dye Intermediates for Wet-End and Finish Applications

    Tanneries and leather finishing plants integrate this raw material in synthesizing water-soluble leather dyes with sulfonic acid groups, supporting deep and uniform penetration into hides and skins. Its controlled introduction helps produce dyes free from banned arylamines, a requirement for export-grade leathers in premium markets. This selection gives distinctive shade purity and reduces aftertreatment costs.

    Industry compliance standards

    • ISO 17234-1:2015 (Determination of certain azo colorants in leather)
    • REACH Annex XVII – Leather articles
    • Leather Working Group (LWG) Restricted Substances List
    • AFIRM RSL (Apparel & Footwear International Restricted Substances List)

    Typical usage ratio

    • 0.2–0.8 molar equivalents relative to coupling partner or prepolymer, tuned for penetration depth and migration stability in substrate; process technicians adjust by suede or grain finish requirements.

    Downstream process integration

    • Incorporated during the synthesis step for pre-dye intermediates or as a blending component in late-stage dye baths; stability checks carried out by UV-Vis/LC-MS during batch prep to meet migration and fastness benchmarks.

    Final product types

    • Aniline-free wet-end dyes
    • Finish coat coloring concentrates
    • Shade-corrected crust leather dyes
    • Automotive and fashion leather finishes

    3. Organic Pigments for Printing Ink and Coating Systems

    The sodium salt form of 2-nitroaniline-4-sulfonic acid finds targeted use in the production of high-purity azo pigment intermediates, crucial for printing inks and specialty coatings. Ink producers favor this intermediate for its clean coupling profile, which contributes to high color strength, resistance to migration, and precise particle size control in applications like flexographic, gravure, and inkjet printing.

    Industry compliance standards

    • EN 71-3:2019 (Migration of certain elements in toys/pigments)
    • Swiss Ordinance on Materials and Articles (SR 817.023.21, Annex 10)
    • ASTM D5067 (Pigment quality for printing inks)
    • GMP Regulation (EC) No 2023/2006 (Printing inks for food packaging)

    Typical usage ratio

    • 0.5–1.2 mol equivalents in pigment synthesis, adjusted according to final pigment surface treatment and dispersibility requirements; laboratories conduct pilot batches before scale-up.

    Downstream process integration

    • Fed into the diazotization-coupling reaction in pigment synthesis; post-reacted pigments often subjected to salt milling and surface treatment before dispersion into ink vehicles.

    Final product types

    • Azo yellow and red pigments for flexographic and gravure inks
    • Toner colorants for electrophotographic systems
    • Resin-bound pigments for protective and decorative coatings
    • Aqueous and solvent-based inkjet dispersions

    4. Paper Coloring Agents for Specialty and Security Grades

    Paper manufacturers, especially in the security, currency, and certificate segment, apply this compound as a key intermediate for synthesizing direct dyes with controlled migration and anti-counterfeit properties. Regulatory audit trails and batch traceability remain central, as paper grades for legal and archival documents demand dyes with minimal leaching and high UV stability.

    Industry compliance standards

    • ISO 187:2022 (Paper and board sampling and conditioning)
    • DIN 54378 (Resistance of dyed paper to water and solvents)
    • REACH Annex XVII (Paper dyes – aromatic amine restrictions)
    • FDA 21 CFR 176.170 (Paper and paperboard in contact with aqueous and fatty foods)

    Typical usage ratio

    • 0.1–0.6% by paper dry weight for direct dye intermediates, adjusted for grammage, brightness, and required anti-migration properties; formulation engineers select precise level during lab validation.

    Downstream process integration

    • Added at dye synthesis stage or as semi-finished concentrate blended into paper mill coloring feeds; integration monitored by in-line colorimeter and migration resistance testing according to end use (tickets, official records, security notes).

    Final product types

    • Banknote and stamp papers
    • Security pattern and watermark papers
    • Archival and certification documents
    • Specialty colored copy and cover stocks

    5. Ion-Exchange Resin Functionalization for Chromatography and Separation Media

    Select manufacturers utilize this raw material to introduce defined sulfonic acid and nitro functionalities into cross-linked aromatic resin matrices, enhancing ion-exchange capacity and improving selectivity for analytical or preparative separation columns. The specificity of functional group placement on the aromatic ring supports resin performance for pharmaceutical, water purification, and food processing chromatography systems where lot uniformity stands as a primary QC concern.

    Industry compliance standards

    • USP <645> (Water Conductivity for pharmaceutical applications)
    • EN 12873-1:2003 (Migration from ion-exchange resins for water use)
    • FDA 21 CFR 173.25 (Ion-exchange resins in food processing)
    • ISO 9001:2015 (Quality management for manufacturing traceability)

    Typical usage ratio

    • 0.8–1.3 mmol/g resin, determined from resin crosslink density, performance in breakthrough curves, and final application (analytical, process-scale, or food-grade separation lines).

    Downstream process integration

    • Introduced during post-polymerization functionalization; sulfonation and nitration controlled via batch or continuous flow reactors; content of active sites verified by titration and spectrophotometric QC before shipment to end users.

    Final product types

    • Cation-exchange resins for water purification systems
    • Bioseparation chromatography media
    • Resins for sugar and sweetener processing
    • Analytical grade ion-exchange columns
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    Certification & Compliance
    More Introduction

    Introducing 2-Nitroaniline-4-Sulfonic Acid Sodium Salt: Quality and Consistency from Source to Solution

    Product Background and Model Information

    Our years producing 2-nitroaniline-4-sulfonic acid sodium salt have taught us that reliability starts long before the chemical leaves the gate. Model NASS-440 reflects a careful evolution in both process and material selection, shaped by customer feedback and practical lessons on the shop floor. Every batch is managed from raw material sourcing to packaging under strict process controls, easing challenges that staff and partners used to report. Transparent records accompany production at each stage, which can shave days off troubleshooting and root cause analysis. These steps may slow speed on the front end, yet extending the cycle brings gains later—fewer production upsets, more repeatable performance, and happier end users.

    Chemical purity in our model sits (as analytical testing by high-performance liquid chromatography confirms) at not less than 98%, which reduces unwanted side-reactions. Moisture content—even in climates with seasonal humidity swings—remains under 1% due to our dedicated drying rooms and sealed handling lines. Granular consistency, often overlooked, stops caking during storage and pouring, a lesson we learned the hard way after several cold winters encouraged bridging in our early silos. Color, sometimes a surrogate for unreacted intermediates, runs a clean pale yellow without gray or rusty overtone. When customers comment about small but impactful changes, we’ve tweaked parameters quickly, learning that open ears make better chemists.

    The Real Uses and Their Realities

    2-nitroaniline-4-sulfonic acid sodium salt persists in many chemical production lines, thanks to its reactive amine and sulfonic acid groups. Most customers call for it as an intermediate for azo dyes—especially in yellow and orange shades—where the consistent nitro positioning controls tone, tint, and even stability against sunlight. In our conversations with dyestuff makers, minor changes in structure sometimes break downstream performance. It took firsthand trial runs and joint pilot projects to learn why precision on our end staves off complaints further down the chain.

    A smaller, but important group uses it in pharmaceutical intermediates, exploiting both electronic and solubilizing effects. The sulfonic acid salt simplifies aqueous handling, meaning simple dissolution instead of elaborate pH adjustment or heating steps. This saves energy and improves safety—a benefit our clients rarely considered until we walked through heating cost data side-by-side. Organic chemists often remind us that slower dissolving products can introduce variability between batches. Our drying and granulation upgrades stemmed from these conversations and from watching frustrated operators in partner facilities.

    Other applications include specialty pigment precursors and polymer additives. We work directly with technical teams at several manufacturers to tune specification ranges, ensuring that their final product colors or physical properties remain in spec. These collaborations also inform our future adjustments, because a reading on a certificate of analysis tells only part of the story.

    Key Differences: How Our Approach Yields a Distinct Product

    Not all 2-nitroaniline-4-sulfonic acid sodium salt performs the same in practical settings. Some makers focus on headline assay and let other characteristics drift. Our own history had this tendency once, until we faced customer lines going off spec due to trace chloride ion or unreacted starting material. It’s easy to dismiss these as minor, but cumulative impacts can sideline a batch or add silent costs—like filter plugging, batch loss, or unscheduled downtime for filter changes. We learned that a product with a robust, consistent impurity profile provides value far beyond its test results.

    The difference comes from the way we control reaction endpoints with redundant instrumentation, along with operator training on visual and analytical cues. We monitor hydrolysis or reduction byproducts carefully, intercepting even low-level contaminants before discharge. In two decades of production, after many customer audits and surprise visits, these choices have made our output less prone to lot-to-lot fluctuations. This means fewer complaints, improved regulatory acceptance, and smoother supply chain certifications for downstream users.

    Our operational philosophy brings the team close to customer production realities. When one major user’s process started fouling filtration units every two months, we sent staff to help run spectra on-site. It turned out that tiny levels of residual potassium, likely from a now-replaced lot of raw reagent, contributed disproportionately to their problem. The fix improved not just their system but also how we verify our incoming streams and cleaning process.

    Real-World Impact: Downstream Process Savings

    Plenty of conversation circles around price or specification sheets, but in our experience the savings stack up more from avoiding headaches than shaving cost per kilo. Dyes produced with consistently pure intermediate process more reliably; less time gets spent reworking or discarding off-color lots. Operators waste less solvent, require shorter filtration cycles, and see steadier yields. In pharmaceutical synthesis, our partners have reported improved crystallization kinetics and less lot-failure due to trace byproducts. Some regulatory submissions have run smoother because batch reproducibility raises reviewer confidence. We never set out to be a regulatory consultancy, yet our consistent outputs have become a passport for our partners facing mounting compliance demands.

    Shipment stability also marks a major difference. Because of our tailored packaging—bags engineered to sweep away static, drums lined for chemical resistance—we notice fewer complaints about caking or moisture pickup, especially in monsoon or snowy seasons. Simple process changes in bag sealing and palletization came only after logistics partners fed back on handling issues in distant ports. A manufacturer can’t ignore these real conditions, and each minor fix inches the product closer to being hassle-free for those who rely on it.

    Improving Safety and Environmental Performance

    Chemical manufacturing involves risk management. Every step of our process reflects direct lessons from near-misses, localized spills, and evolving operator routines. Handling 2-nitroaniline-4-sulfonic acid sodium salt used to rely heavily on personal protective gear and luck, especially in older facilities lacking modern containment. Recognizing the limits of PPE, we invested in closed charging systems, automated feeders, and backup sensors in transfer zones. Spills plummeted. The transition wasn’t easy or cost-free, and line staff struggled until familiarity set in, but the impact registers daily: less downtime, fewer minor injuries, and improved morale.

    Wastewater streams from our sulfonation steps contain both organic and inorganic load. We route all process water through multi-stage treatment, separating solids, neutralizing acidity, and removing organics before blending with municipal effluent. This system grew out of joint audits with local regulators and monthly data reviews. There is pride in staying below environmental thresholds, not because it avoids fines but because it aligns with our responsibility as stewards of the local community and ecosystem.

    We also recycle side-products, using spent acid in neutralization and heat recovery from exothermic steps to reduce utility draw. It doesn’t always pencil out as the easiest route, yet over the years, efficiency gains and reputational benefits have outweighed initial costs. Our partners appreciate running their own lines without added environmental headaches linked to poorly controlled upstream practices.

    Supporting End-User Innovation

    New product development thrives on reliable building blocks. When a research team asks for a batch with tighter control of isomer ratio or a slightly narrower particle size range, we mobilize quickly. Small-scale reactors, pilot lots, and real-time analytical support blend into our routine, as regular customer requests foster our own continuous improvement. Our technical support engineers frequently cross over between plant floor and customer site, breaking down silos between chemistry and application.

    For dye houses developing colors for sensitive textile applications, we customize on-spec material for prototype runs, keeping impurity profiles documented over numerous batches. This transparency supports our clients’ own innovation without risking scale-up failures. It’s better for both supplier and user to address these needs before full rollout than wrestle with unexpected variability that can eat budgets and time.

    Pharmaceutical partners likewise rely on us for batch-to-batch data transparency. Sometimes development programs need tighter control on a single impurity profile for consistent pharmacology. Close dialogue in these cases helps us fine-tune drying, purification, or reaction times, all within tightly monitored production windows.

    Handling Logistical and Regulatory Complexities

    Moving 2-nitroaniline-4-sulfonic acid sodium salt internationally challenges both paperwork and patience. We document product origin, route, and batch all the way to customer gate in both digital and hard copy, so each pallet’s history remains clear. Quality managers in customer firms sometimes request supporting analyses or supply chain trace lines months after shipment. By storing data for years and training staff on regulatory shifts—including the quirks of chemical labeling laws and transport codes—we help smooth import clearances, even as national guidelines evolve.

    Our compliance team partners with outside experts to read the regulatory weather. Shifting limits for certain anilines, fresh requirements for GHS hazard communication, and export controls for potential dual-use chemicals all affect our sector. We work upstream to integrate these changes into regular production cycles, sheltering end users from panic at short notice or abrupt product gaps.

    From experience, maintaining buffer stocks and rapid redirect capacity—things only possible when manufacturing direct—means that earthquake, flood, or vessel backlog disrupts supply less severely than some competitors. End users have remarked, sometimes in crisis, that consistent direct-from-manufacturer access saves months of production rather than weeks.

    Continuous Improvement from Feedback and Direct Experience

    Direct lines between plant, technical support, and customer, which we have tended for decades, shape every meaningful improvement. When users of our 2-nitroaniline-4-sulfonic acid sodium salt mention application headaches—delayed color development, filter plugging, variable dissolution rates—we bring those complaints home to our lab. Cross-checks of chromatography, pilot syntheses in mini-reactors, and customer process simulation help us identify subtle sources. Sometimes a tiny tweak in the crystallization stage or a change in centrifuge settings brings measurable gains.

    Not all improvements flow from formal complaints. Plant operators themselves spot sticky residues, color drift, or subtle clumping and voice these through our long-standing improvement system. Management invests the time and energy to let line staff steer process upgrades, shelving obsolete gear and upgrading control panels based on real-world experience rather than guesswork or vendor sales talk.

    Each step increases both product consistency and staff pride—a feedback loop driving higher quality product and fewer headaches down the value chain. Our customers and end-use partners deserve a supplier with skin in the game, using process discipline and open communication as foundation stones.

    Setting Expectations: What Direct Manufacturing Means for Our Partners

    Working directly with a manufacturer rather than distributor opens doors to innovation and buffer protection against upstream risk. We field technical inquiries at all levels: whether on the right solvent for dissolution, strategies for reducing micro-contamination, or tips on mild pH operation. End users appreciate more than just product—it’s the hand-in-glove support before, during, and after a run that makes the difference.

    Challenges remain in any specialty chemical scene: demand can spike unexpectedly, standards can shift, and batches can fall wide of spec. Our promise rests not simply on hitting a percentage figure, but on rapid correction, open dialogue, and the willingness to adapt process or logistics. Partners that have run with us for years often cite not only steady performance but also the comfort of consistent communication and credible root-cause investigation when surprises crop up. That confidence, built batch by batch, forms our real value in an industry often buffeted by interruptions, new regulations, and shifting end-market needs.

    2-nitroaniline-4-sulfonic acid sodium salt offers more than a chemical feedstock. Through deliberate engineering, committed teamwork, and hard-won lessons on both failure and success, we keep forging a path that brings benefits to the shop floor and the boardroom table alike. Our team, tuned by years of practical obstacles, stands ready to shoulder not just supply, but a role as problem solver and application partner throughout the journey from raw molecule to final product.